Kun Qian, Hailong Huang, Andrew Peterson, Baoyang Hu, Nicholas J Maragakis, Guo-Li Ming, Hong Chen, Su-Chun Zhang. Stem Cell Reports 2017
Times Cited: 70
Times Cited: 70
Times Cited
Times Co-cited
Similarity
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.
Amanda M Haidet-Phillips, Mark E Hester, Carlos J Miranda, Kathrin Meyer, Lyndsey Braun, Ashley Frakes, SungWon Song, Shibi Likhite, Matthew J Murtha, Kevin D Foust,[...]. Nat Biotechnol 2011
Amanda M Haidet-Phillips, Mark E Hester, Carlos J Miranda, Kathrin Meyer, Lyndsey Braun, Ashley Frakes, SungWon Song, Shibi Likhite, Matthew J Murtha, Kevin D Foust,[...]. Nat Biotechnol 2011
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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
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Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS.
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
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Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
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Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Andrea Serio, Bilada Bilican, Sami J Barmada, Dale Michael Ando, Chen Zhao, Rick Siller, Karen Burr, Ghazal Haghi, David Story, Agnes Lumi Nishimura,[...]. Proc Natl Acad Sci U S A 2013
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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model.
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
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Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms.
Martin Madill, Katya McDonagh, Jun Ma, Alice Vajda, Paul McLoughlin, Timothy O'Brien, Orla Hardiman, Sanbing Shen. Mol Brain 2017
Martin Madill, Katya McDonagh, Jun Ma, Alice Vajda, Paul McLoughlin, Timothy O'Brien, Orla Hardiman, Sanbing Shen. Mol Brain 2017
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Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.
Claire E Hall, Zhi Yao, Minee Choi, Giulia E Tyzack, Andrea Serio, Raphaelle Luisier, Jasmine Harley, Elisavet Preza, Charlie Arber, Sarah J Crisp,[...]. Cell Rep 2017
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Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity.
Anastasya Birger, Israel Ben-Dor, Miri Ottolenghi, Tikva Turetsky, Yaniv Gil, Sahar Sweetat, Liat Perez, Vitali Belzer, Natania Casden, Debora Steiner,[...]. EBioMedicine 2019
Anastasya Birger, Israel Ben-Dor, Miri Ottolenghi, Tikva Turetsky, Yaniv Gil, Sahar Sweetat, Liat Perez, Vitali Belzer, Natania Casden, Debora Steiner,[...]. EBioMedicine 2019
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Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.
Akshata A Almad, Arpitha Doreswamy, Sarah K Gross, Jean-Philippe Richard, Yuqing Huo, Norman Haughey, Nicholas J Maragakis. Glia 2016
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Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells.
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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
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PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease.
Minna Oksanen, Andrew J Petersen, Nikolay Naumenko, Katja Puttonen, Šárka Lehtonen, Max Gubert Olivé, Anastasia Shakirzyanova, Stina Leskelä, Timo Sarajärvi, Matti Viitanen,[...]. Stem Cell Reports 2017
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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
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Onset and progression in inherited ALS determined by motor neurons and microglia.
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Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease.
Angelo C Lepore, Britta Rauck, Christine Dejea, Andrea C Pardo, Mahendra S Rao, Jeffrey D Rothstein, Nicholas J Maragakis. Nat Neurosci 2008
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Necroptosis drives motor neuron death in models of both sporadic and familial ALS.
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Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.
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Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.
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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
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Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism.
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Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.
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Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
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Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.
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Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress.
Fabiola Rojas, Nicole Cortes, Sebastian Abarzua, Agnieszka Dyrda, Brigitte van Zundert. Front Cell Neurosci 2014
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Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats.
Jianbin Tong, Cao Huang, Fangfang Bi, Qinxue Wu, Bo Huang, Xionghao Liu, Fang Li, Hongxia Zhou, Xu-Gang Xia. EMBO J 2013
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A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models.
Giulia E Tyzack, Claire E Hall, Christopher R Sibley, Tomasz Cymes, Serhiy Forostyak, Giulia Carlino, Ione F Meyer, Giampietro Schiavo, Su-Chun Zhang, George M Gibbons,[...]. Nat Commun 2017
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Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.
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Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1.
Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R Klim, A Sophie de Boer, Sahil Agrawal, Jackson Sandoe, Claudia S Lopes, Karolyn Sassi Ogliari, Luis A Williams, Matthew Shear,[...]. Stem Cell Reports 2017
Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R Klim, A Sophie de Boer, Sahil Agrawal, Jackson Sandoe, Claudia S Lopes, Karolyn Sassi Ogliari, Luis A Williams, Matthew Shear,[...]. Stem Cell Reports 2017
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Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Kazutoshi Takahashi, Shinya Yamanaka. Cell 2006
Kazutoshi Takahashi, Shinya Yamanaka. Cell 2006
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Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS.
André Varcianna, Monika A Myszczynska, Lydia M Castelli, Brendan O'Neill, Yeseul Kim, Jordan Talbot, Sophie Nyberg, Immanuelle Nyamali, Paul R Heath, Matthew J Stopford,[...]. EBioMedicine 2019
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Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology.
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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond.
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Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells.
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Focal transplantation of human iPSC-derived glial-rich neural progenitors improves lifespan of ALS mice.
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Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways.
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Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse.
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RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention.
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Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha.
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Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.
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Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease.
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Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis.
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Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.
Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
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C9orf72 is required for proper macrophage and microglial function in mice.
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Human-derived neural progenitors functionally replace astrocytes in adult mice.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.