Fuguo Jiang, Jennifer A Doudna. Annu Rev Biophys 2017
Times Cited: 619
Times Cited: 619
Times Cited
Times Co-cited
Similarity
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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Multiplex genome engineering using CRISPR/Cas systems.
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Genome editing. The new frontier of genome engineering with CRISPR-Cas9.
Jennifer A Doudna, Emmanuelle Charpentier. Science 2014
Jennifer A Doudna, Emmanuelle Charpentier. Science 2014
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Crystal structure of Cas9 in complex with guide RNA and target DNA.
Hiroshi Nishimasu, F Ann Ran, Patrick D Hsu, Silvana Konermann, Soraya I Shehata, Naoshi Dohmae, Ryuichiro Ishitani, Feng Zhang, Osamu Nureki. Cell 2014
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CRISPR provides acquired resistance against viruses in prokaryotes.
Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau, Melissa Richards, Patrick Boyaval, Sylvain Moineau, Dennis A Romero, Philippe Horvath. Science 2007
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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.
Giedrius Gasiunas, Rodolphe Barrangou, Philippe Horvath, Virginijus Siksnys. Proc Natl Acad Sci U S A 2012
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Search-and-replace genome editing without double-strand breaks or donor DNA.
Andrew V Anzalone, Peyton B Randolph, Jessie R Davis, Alexander A Sousa, Luke W Koblan, Jonathan M Levy, Peter J Chen, Christopher Wilson, Gregory A Newby, Aditya Raguram,[...]. Nature 2019
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Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product.
Y Ishino, H Shinagawa, K Makino, M Amemura, A Nakata. J Bacteriol 1987
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Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
Bernd Zetsche, Jonathan S Gootenberg, Omar O Abudayyeh, Ian M Slaymaker, Kira S Makarova, Patrick Essletzbichler, Sara E Volz, Julia Joung, John van der Oost, Aviv Regev,[...]. Cell 2015
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
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RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
15
Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.
Carolin Anders, Ole Niewoehner, Alessia Duerst, Martin Jinek. Nature 2014
Carolin Anders, Ole Niewoehner, Alessia Duerst, Martin Jinek. Nature 2014
15
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Martin Jinek, Fuguo Jiang, David W Taylor, Samuel H Sternberg, Emine Kaya, Enbo Ma, Carolin Anders, Michael Hauer, Kaihong Zhou, Steven Lin,[...]. Science 2014
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15
Rationally engineered Cas9 nucleases with improved specificity.
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
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15
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
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14
Nucleic acid detection with CRISPR-Cas13a/C2c2.
Jonathan S Gootenberg, Omar O Abudayyeh, Jeong Wook Lee, Patrick Essletzbichler, Aaron J Dy, Julia Joung, Vanessa Verdine, Nina Donghia, Nichole M Daringer, Catherine A Freije,[...]. Science 2017
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ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering.
Thomas Gaj, Charles A Gersbach, Carlos F Barbas. Trends Biotechnol 2013
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Development and applications of CRISPR-Cas9 for genome engineering.
Patrick D Hsu, Eric S Lander, Feng Zhang. Cell 2014
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Delivering CRISPR: a review of the challenges and approaches.
Christopher A Lino, Jason C Harper, James P Carney, Jerilyn A Timlin. Drug Deliv 2018
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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
13
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III.
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13
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.
Janice S Chen, Enbo Ma, Lucas B Harrington, Maria Da Costa, Xinran Tian, Joel M Palefsky, Jennifer A Doudna. Science 2018
Janice S Chen, Enbo Ma, Lucas B Harrington, Maria Da Costa, Xinran Tian, Joel M Palefsky, Jennifer A Doudna. Science 2018
13
Genome engineering using the CRISPR-Cas9 system.
F Ann Ran, Patrick D Hsu, Jason Wright, Vineeta Agarwala, David A Scott, Feng Zhang. Nat Protoc 2013
F Ann Ran, Patrick D Hsu, Jason Wright, Vineeta Agarwala, David A Scott, Feng Zhang. Nat Protoc 2013
13
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.
Omar O Abudayyeh, Jonathan S Gootenberg, Silvana Konermann, Julia Joung, Ian M Slaymaker, David B T Cox, Sergey Shmakov, Kira S Makarova, Ekaterina Semenova, Leonid Minakhin,[...]. Science 2016
Omar O Abudayyeh, Jonathan S Gootenberg, Silvana Konermann, Julia Joung, Ian M Slaymaker, David B T Cox, Sergey Shmakov, Kira S Makarova, Ekaterina Semenova, Leonid Minakhin,[...]. Science 2016
12
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
Samuel H Sternberg, Sy Redding, Martin Jinek, Eric C Greene, Jennifer A Doudna. Nature 2014
Samuel H Sternberg, Sy Redding, Martin Jinek, Eric C Greene, Jennifer A Doudna. Nature 2014
12
Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.
Janice S Chen, Yavuz S Dagdas, Benjamin P Kleinstiver, Moira M Welch, Alexander A Sousa, Lucas B Harrington, Samuel H Sternberg, J Keith Joung, Ahmet Yildiz, Jennifer A Doudna. Nature 2017
Janice S Chen, Yavuz S Dagdas, Benjamin P Kleinstiver, Moira M Welch, Alexander A Sousa, Lucas B Harrington, Samuel H Sternberg, J Keith Joung, Ahmet Yildiz, Jennifer A Doudna. Nature 2017
12
DNA targeting specificity of RNA-guided Cas9 nucleases.
Patrick D Hsu, David A Scott, Joshua A Weinstein, F Ann Ran, Silvana Konermann, Vineeta Agarwala, Yinqing Li, Eli J Fine, Xuebing Wu, Ophir Shalem,[...]. Nat Biotechnol 2013
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11
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
11
Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins.
Sojung Kim, Daesik Kim, Seung Woo Cho, Jungeun Kim, Jin-Soo Kim. Genome Res 2014
Sojung Kim, Daesik Kim, Seung Woo Cho, Jungeun Kim, Jin-Soo Kim. Genome Res 2014
11
Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer.
You Lu, Jianxin Xue, Tao Deng, Xiaojuan Zhou, Kun Yu, Lei Deng, Meijuan Huang, Xin Yi, Maozhi Liang, Yu Wang,[...]. Nat Med 2020
You Lu, Jianxin Xue, Tao Deng, Xiaojuan Zhou, Kun Yu, Lei Deng, Meijuan Huang, Xin Yi, Maozhi Liang, Yu Wang,[...]. Nat Med 2020
10
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
Yanfang Fu, Jennifer A Foden, Cyd Khayter, Morgan L Maeder, Deepak Reyon, J Keith Joung, Jeffry D Sander. Nat Biotechnol 2013
Yanfang Fu, Jennifer A Foden, Cyd Khayter, Morgan L Maeder, Deepak Reyon, J Keith Joung, Jeffry D Sander. Nat Biotechnol 2013
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Field-deployable viral diagnostics using CRISPR-Cas13.
Cameron Myhrvold, Catherine A Freije, Jonathan S Gootenberg, Omar O Abudayyeh, Hayden C Metsky, Ann F Durbin, Max J Kellner, Amanda L Tan, Lauren M Paul, Leda A Parham,[...]. Science 2018
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10
Base editing: precision chemistry on the genome and transcriptome of living cells.
Holly A Rees, David R Liu. Nat Rev Genet 2018
Holly A Rees, David R Liu. Nat Rev Genet 2018
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CRISPR-engineered T cells in patients with refractory cancer.
Edward A Stadtmauer, Joseph A Fraietta, Megan M Davis, Adam D Cohen, Kristy L Weber, Eric Lancaster, Patricia A Mangan, Irina Kulikovskaya, Minnal Gupta, Fang Chen,[...]. Science 2020
Edward A Stadtmauer, Joseph A Fraietta, Megan M Davis, Adam D Cohen, Kristy L Weber, Eric Lancaster, Patricia A Mangan, Irina Kulikovskaya, Minnal Gupta, Fang Chen,[...]. Science 2020
9
History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology.
Yoshizumi Ishino, Mart Krupovic, Patrick Forterre. J Bacteriol 2018
Yoshizumi Ishino, Mart Krupovic, Patrick Forterre. J Bacteriol 2018
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Diversity, classification and evolution of CRISPR-Cas systems.
Eugene V Koonin, Kira S Makarova, Feng Zhang. Curr Opin Microbiol 2017
Eugene V Koonin, Kira S Makarova, Feng Zhang. Curr Opin Microbiol 2017
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STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition.
Fuguo Jiang, Kaihong Zhou, Linlin Ma, Saskia Gressel, Jennifer A Doudna. Science 2015
Fuguo Jiang, Kaihong Zhou, Linlin Ma, Saskia Gressel, Jennifer A Doudna. Science 2015
9
In vivo genome editing using Staphylococcus aureus Cas9.
F Ann Ran, Le Cong, Winston X Yan, David A Scott, Jonathan S Gootenberg, Andrea J Kriz, Bernd Zetsche, Ophir Shalem, Xuebing Wu, Kira S Makarova,[...]. Nature 2015
F Ann Ran, Le Cong, Winston X Yan, David A Scott, Jonathan S Gootenberg, Andrea J Kriz, Bernd Zetsche, Ophir Shalem, Xuebing Wu, Kira S Makarova,[...]. Nature 2015
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Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors.
Andrew V Anzalone, Luke W Koblan, David R Liu. Nat Biotechnol 2020
Andrew V Anzalone, Luke W Koblan, David R Liu. Nat Biotechnol 2020
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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA.
Josiane E Garneau, Marie-Ève Dupuis, Manuela Villion, Dennis A Romero, Rodolphe Barrangou, Patrick Boyaval, Christophe Fremaux, Philippe Horvath, Alfonso H Magadán, Sylvain Moineau. Nature 2010
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9
A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing.
Jonathan D Finn, Amy Rhoden Smith, Mihir C Patel, Lucinda Shaw, Madeleine R Youniss, Jane van Heteren, Tanner Dirstine, Corey Ciullo, Reynald Lescarbeau, Jessica Seitzer,[...]. Cell Rep 2018
Jonathan D Finn, Amy Rhoden Smith, Mihir C Patel, Lucinda Shaw, Madeleine R Youniss, Jane van Heteren, Tanner Dirstine, Corey Ciullo, Reynald Lescarbeau, Jessica Seitzer,[...]. Cell Rep 2018
8
RNA editing with CRISPR-Cas13.
David B T Cox, Jonathan S Gootenberg, Omar O Abudayyeh, Brian Franklin, Max J Kellner, Julia Joung, Feng Zhang. Science 2017
David B T Cox, Jonathan S Gootenberg, Omar O Abudayyeh, Brian Franklin, Max J Kellner, Julia Joung, Feng Zhang. Science 2017
8
RNA targeting with CRISPR-Cas13.
Omar O Abudayyeh, Jonathan S Gootenberg, Patrick Essletzbichler, Shuo Han, Julia Joung, Joseph J Belanto, Vanessa Verdine, David B T Cox, Max J Kellner, Aviv Regev,[...]. Nature 2017
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8
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
F Ann Ran, Patrick D Hsu, Chie-Yu Lin, Jonathan S Gootenberg, Silvana Konermann, Alexandro E Trevino, David A Scott, Azusa Inoue, Shogo Matoba, Yi Zhang,[...]. Cell 2013
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CRISPR-CasΦ from huge phages is a hypercompact genome editor.
Patrick Pausch, Basem Al-Shayeb, Ezra Bisom-Rapp, Connor A Tsuchida, Zheng Li, Brady F Cress, Gavin J Knott, Steven E Jacobsen, Jillian F Banfield, Jennifer A Doudna. Science 2020
Patrick Pausch, Basem Al-Shayeb, Ezra Bisom-Rapp, Connor A Tsuchida, Zheng Li, Brady F Cress, Gavin J Knott, Steven E Jacobsen, Jillian F Banfield, Jennifer A Doudna. Science 2020
8
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects.
Hongyi Li, Yang Yang, Weiqi Hong, Mengyuan Huang, Min Wu, Xia Zhao. Signal Transduct Target Ther 2020
Hongyi Li, Yang Yang, Weiqi Hong, Mengyuan Huang, Min Wu, Xia Zhao. Signal Transduct Target Ther 2020
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Identification of genes that are associated with DNA repeats in prokaryotes.
Ruud Jansen, Jan D A van Embden, Wim Gaastra, Leo M Schouls. Mol Microbiol 2002
Ruud Jansen, Jan D A van Embden, Wim Gaastra, Leo M Schouls. Mol Microbiol 2002
8
Identification of preexisting adaptive immunity to Cas9 proteins in humans.
Carsten T Charlesworth, Priyanka S Deshpande, Daniel P Dever, Joab Camarena, Viktor T Lemgart, M Kyle Cromer, Christopher A Vakulskas, Michael A Collingwood, Liyang Zhang, Nicole M Bode,[...]. Nat Med 2019
Carsten T Charlesworth, Priyanka S Deshpande, Daniel P Dever, Joab Camarena, Viktor T Lemgart, M Kyle Cromer, Christopher A Vakulskas, Michael A Collingwood, Liyang Zhang, Nicole M Bode,[...]. Nat Med 2019
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.