A citation-based method for searching scientific literature

Claire Vennin, Venessa T Chin, Sean C Warren, Morghan C Lucas, David Herrmann, Astrid Magenau, Pauline Melenec, Stacey N Walters, Gonzalo Del Monte-Nieto, James R W Conway, Max Nobis, Amr H Allam, Rachael A McCloy, Nicola Currey, Mark Pinese, Alice Boulghourjian, Anaiis Zaratzian, Arne A S Adam, Celine Heu, Adnan M Nagrial, Angela Chou, Angela Steinmann, Alison Drury, Danielle Froio, Marc Giry-Laterriere, Nathanial L E Harris, Tri Phan, Rohit Jain, Wolfgang Weninger, Ewan J McGhee, Renee Whan, Amber L Johns, Jaswinder S Samra, Lorraine Chantrill, Anthony J Gill, Maija Kohonen-Corish, Richard P Harvey, Andrew V Biankin, T R Jeffry Evans, Kurt I Anderson, Shane T Grey, Christopher J Ormandy, David Gallego-Ortega, Yingxiao Wang, Michael S Samuel, Owen J Sansom, Andrew Burgess, Thomas R Cox, Jennifer P Morton, Marina Pajic, Paul Timpson. Sci Transl Med 2017
Times Cited: 147







List of co-cited articles
1491 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.
Berna C Özdemir, Tsvetelina Pentcheva-Hoang, Julienne L Carstens, Xiaofeng Zheng, Chia-Chin Wu, Tyler R Simpson, Hanane Laklai, Hikaru Sugimoto, Christoph Kahlert, Sergey V Novitskiy,[...]. Cancer Cell 2014
31

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Kenneth P Olive, Michael A Jacobetz, Christian J Davidson, Aarthi Gopinathan, Dominick McIntyre, Davina Honess, Basetti Madhu, Mae A Goldgraben, Meredith E Caldwell, David Allard,[...]. Science 2009
27

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma.
Paolo P Provenzano, Carlos Cuevas, Amy E Chang, Vikas K Goel, Daniel D Von Hoff, Sunil R Hingorani. Cancer Cell 2012
25

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.
Andrew D Rhim, Paul E Oberstein, Dafydd H Thomas, Emily T Mirek, Carmine F Palermo, Stephen A Sastra, Erin N Dekleva, Tyler Saunders, Claudia P Becerra, Ian W Tattersall,[...]. Cancer Cell 2014
25

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Hanane Laklai, Yekaterina A Miroshnikova, Michael W Pickup, Eric A Collisson, Grace E Kim, Alex S Barrett, Ryan C Hill, Johnathon N Lakins, David D Schlaepfer, Janna K Mouw,[...]. Nat Med 2016
305
24

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth.
Nicola Rath, Jennifer P Morton, Linda Julian, Lena Helbig, Shereen Kadir, Ewan J McGhee, Kurt I Anderson, Gabriela Kalna, Margaret Mullin, Andreia V Pinho,[...]. EMBO Mol Med 2017
80
30

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
Daniel Öhlund, Abram Handly-Santana, Giulia Biffi, Ela Elyada, Ana S Almeida, Mariano Ponz-Sarvise, Vincenzo Corbo, Tobiloba E Oni, Stephen A Hearn, Eun Jung Lee,[...]. J Exp Med 2017
821
21

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.
Michael A Jacobetz, Derek S Chan, Albrecht Neesse, Tashinga E Bapiro, Natalie Cook, Kristopher K Frese, Christine Feig, Tomoaki Nakagawa, Meredith E Caldwell, Heather I Zecchini,[...]. Gut 2013
626
20

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.
Hong Jiang, Samarth Hegde, Brett L Knolhoff, Yu Zhu, John M Herndon, Melissa A Meyer, Timothy M Nywening, William G Hawkins, Irina M Shapiro, David T Weaver,[...]. Nat Med 2016
479
20

Matrix crosslinking forces tumor progression by enhancing integrin signaling.
Kandice R Levental, Hongmei Yu, Laura Kass, Johnathon N Lakins, Mikala Egeblad, Janine T Erler, Sheri F T Fong, Katalin Csiszar, Amato Giaccia, Wolfgang Weninger,[...]. Cell 2009
19

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.
Mara H Sherman, Ruth T Yu, Dannielle D Engle, Ning Ding, Annette R Atkins, Herve Tiriac, Eric A Collisson, Frances Connor, Terry Van Dyke, Serguei Kozlov,[...]. Cell 2014
588
19

HALO 202: Randomized Phase II Study of PEGPH20 Plus Nab-Paclitaxel/Gemcitabine Versus Nab-Paclitaxel/Gemcitabine in Patients With Untreated, Metastatic Pancreatic Ductal Adenocarcinoma.
Sunil R Hingorani, Lei Zheng, Andrea J Bullock, Tara E Seery, William P Harris, Darren S Sigal, Fadi Braiteh, Paul S Ritch, Mark M Zalupski, Nathan Bahary,[...]. J Clin Oncol 2018
226
17

Genomic analyses identify molecular subtypes of pancreatic cancer.
Peter Bailey, David K Chang, Katia Nones, Amber L Johns, Ann-Marie Patch, Marie-Claude Gingras, David K Miller, Angelika N Christ, Tim J C Bruxner, Michael C Quinn,[...]. Nature 2016
17


CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan.
Claire Vennin, Pauline Mélénec, Romain Rouet, Max Nobis, Aurélie S Cazet, Kendelle J Murphy, David Herrmann, Daniel A Reed, Morghan C Lucas, Sean C Warren,[...]. Nat Commun 2019
90
17

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.
Bryan W Miller, Jennifer P Morton, Mark Pinese, Grazia Saturno, Nigel B Jamieson, Ewan McGhee, Paul Timpson, Joshua Leach, Lynn McGarry, Emma Shanks,[...]. EMBO Mol Med 2015
157
15

Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth.
Michael S Samuel, Jose I Lopez, Ewan J McGhee, Daniel R Croft, David Strachan, Paul Timpson, June Munro, Ewald Schröder, Jing Zhou, Valerie G Brunton,[...]. Cancer Cell 2011
359
15

Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer.
Claire Vennin, Kendelle J Murphy, Jennifer P Morton, Thomas R Cox, Marina Pajic, Paul Timpson. Gastroenterology 2018
113
15

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.
Richard A Moffitt, Raoud Marayati, Elizabeth L Flate, Keith E Volmar, S Gabriela Herrera Loeza, Katherine A Hoadley, Naim U Rashid, Lindsay A Williams, Samuel C Eaton, Alexander H Chung,[...]. Nat Genet 2015
816
15

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels.
Vikash P Chauhan, John D Martin, Hao Liu, Delphine A Lacorre, Saloni R Jain, Sergey V Kozin, Triantafyllos Stylianopoulos, Ahmed S Mousa, Xiaoxing Han, Pichet Adstamongkonkul,[...]. Nat Commun 2013
500
15

Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer.
Daniel V T Catenacci, Melissa R Junttila, Theodore Karrison, Nathan Bahary, Margit N Horiba, Sreenivasa R Nattam, Robert Marsh, James Wallace, Mark Kozloff, Lakshmi Rajdev,[...]. J Clin Oncol 2015
288
14

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine.
Daniel D Von Hoff, Thomas Ervin, Francis P Arena, E Gabriela Chiorean, Jeffrey Infante, Malcolm Moore, Thomas Seay, Sergei A Tjulandin, Wen Wee Ma, Mansoor N Saleh,[...]. N Engl J Med 2013
14

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.
Christine Feig, James O Jones, Matthew Kraman, Richard J B Wells, Andrew Deonarine, Derek S Chan, Claire M Connell, Edward W Roberts, Qi Zhao, Otavia L Caballero,[...]. Proc Natl Acad Sci U S A 2013
958
14

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.
Ela Elyada, Mohan Bolisetty, Pasquale Laise, William F Flynn, Elise T Courtois, Richard A Burkhart, Jonathan A Teinor, Pascal Belleau, Giulia Biffi, Matthew S Lucito,[...]. Cancer Discov 2019
404
14

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer.
Thierry Conroy, Françoise Desseigne, Marc Ychou, Olivier Bouché, Rosine Guimbaud, Yves Bécouarn, Antoine Adenis, Jean-Luc Raoul, Sophie Gourgou-Bourgade, Christelle de la Fouchardière,[...]. N Engl J Med 2011
13

Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth.
Nicola Rath, June Munro, Marie Francene Cutiongco, Alicja Jagiełło, Nikolaj Gadegaard, Lynn McGarry, Mathieu Unbekandt, Evdokia Michalopoulou, Jurre J Kamphorst, David Sumpton,[...]. Cancer Res 2018
39
33

Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors.
Benjamin Diop-Frimpong, Vikash P Chauhan, Stephen Krane, Yves Boucher, Rakesh K Jain. Proc Natl Acad Sci U S A 2011
411
13

IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma.
Giulia Biffi, Tobiloba E Oni, Benjamin Spielman, Yuan Hao, Ela Elyada, Youngkyu Park, Jonathan Preall, David A Tuveson. Cancer Discov 2019
359
13

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.
Max Nobis, David Herrmann, Sean C Warren, Shereen Kadir, Wilfred Leung, Monica Killen, Astrid Magenau, David Stevenson, Morghan C Lucas, Nadine Reischmann,[...]. Cell Rep 2017
56
21

Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
John J Lee, Rushika M Perera, Huaijun Wang, Dai-Chen Wu, X Shawn Liu, Shiwei Han, Julien Fitamant, Phillip D Jones, Krishna S Ghanta, Sally Kawano,[...]. Proc Natl Acad Sci U S A 2014
305
12

Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States.
Lola Rahib, Benjamin D Smith, Rhonda Aizenberg, Allison B Rosenzweig, Julie M Fleshman, Lynn M Matrisian. Cancer Res 2014
12

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells.
Cedric Gaggioli, Steven Hooper, Cristina Hidalgo-Carcedo, Robert Grosse, John F Marshall, Kevin Harrington, Erik Sahai. Nat Cell Biol 2007
968
12

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.
Fernando Calvo, Nil Ege, Araceli Grande-Garcia, Steven Hooper, Robert P Jenkins, Shahid I Chaudhry, Kevin Harrington, Peter Williamson, Emad Moeendarbary, Guillaume Charras,[...]. Nat Cell Biol 2013
705
12

A framework for advancing our understanding of cancer-associated fibroblasts.
Erik Sahai, Igor Astsaturov, Edna Cukierman, David G DeNardo, Mikala Egeblad, Ronald M Evans, Douglas Fearon, Florian R Greten, Sunil R Hingorani, Tony Hunter,[...]. Nat Rev Cancer 2020
699
12

Whole genomes redefine the mutational landscape of pancreatic cancer.
Nicola Waddell, Marina Pajic, Ann-Marie Patch, David K Chang, Karin S Kassahn, Peter Bailey, Amber L Johns, David Miller, Katia Nones, Kelly Quek,[...]. Nature 2015
11

Remodelling the extracellular matrix in development and disease.
Caroline Bonnans, Jonathan Chou, Zena Werb. Nat Rev Mol Cell Biol 2014
11

ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion.
Antonios Chronopoulos, Benjamin Robinson, Muge Sarper, Ernesto Cortes, Vera Auernheimer, Dariusz Lachowski, Simon Attwood, Rebeca García, Saba Ghassemi, Ben Fabry,[...]. Nat Commun 2016
137
11

A Phase I Study of FOLFIRINOX Plus IPI-926, a Hedgehog Pathway Inhibitor, for Advanced Pancreatic Adenocarcinoma.
Andrew H Ko, Noelle LoConte, Margaret A Tempero, Evan J Walker, R Kate Kelley, Stephanie Lewis, Wei-Chou Chang, Emily Kantoff, Michael W Vannier, Daniel V Catenacci,[...]. Pancreas 2016
122
11

Tensional homeostasis and the malignant phenotype.
Matthew J Paszek, Nastaran Zahir, Kandice R Johnson, Johnathon N Lakins, Gabriela I Rozenberg, Amit Gefen, Cynthia A Reinhart-King, Susan S Margulies, Micah Dembo, David Boettiger,[...]. Cancer Cell 2005
11

Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors.
Hélène Salmon, Katarzyna Franciszkiewicz, Diane Damotte, Marie-Caroline Dieu-Nosjean, Pierre Validire, Alain Trautmann, Fathia Mami-Chouaib, Emmanuel Donnadieu. J Clin Invest 2012
436
11

The extracellular matrix modulates the hallmarks of cancer.
Michael W Pickup, Janna K Mouw, Valerie M Weaver. EMBO Rep 2014
852
10

Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling.
Eishu Hirata, Maria Romina Girotti, Amaya Viros, Steven Hooper, Bradley Spencer-Dene, Michiyuki Matsuda, James Larkin, Richard Marais, Erik Sahai. Cancer Cell 2015
331
10

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice.
Sunil R Hingorani, Lifu Wang, Asha S Multani, Chelsea Combs, Therese B Deramaudt, Ralph H Hruban, Anil K Rustgi, Sandy Chang, David A Tuveson. Cancer Cell 2005
10

Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53.
Paul Timpson, Ewan J McGhee, Jennifer P Morton, Alex von Kriegsheim, Juliane P Schwarz, Saadia A Karim, Brendan Doyle, Jean A Quinn, Neil O Carragher, Mike Edward,[...]. Cancer Res 2011
105
10

Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer.
Clifford J Whatcott, Serina Ng, Michael T Barrett, Galen Hostetter, Daniel D Von Hoff, Haiyong Han. PLoS One 2017
40
25

Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma.
Abasi Ene-Obong, Andrew J Clear, Jennifer Watt, Jun Wang, Rewas Fatah, John C Riches, John F Marshall, Joanne Chin-Aleong, Claude Chelala, John G Gribben,[...]. Gastroenterology 2013
279
10

Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis.
Jacky G Goetz, Susana Minguet, Inmaculada Navarro-Lérida, Juan José Lazcano, Rafael Samaniego, Enrique Calvo, Marta Tello, Teresa Osteso-Ibáñez, Teijo Pellinen, Asier Echarri,[...]. Cell 2011
462
10

Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer.
Sunil R Hingorani, William P Harris, J Thaddeus Beck, Boris A Berdov, Stephanie A Wagner, Eduard M Pshevlotsky, Sergei A Tjulandin, Oleg A Gladkov, Randall F Holcombe, Ronald Korn,[...]. Clin Cancer Res 2016
196
10

The extracellular matrix: a dynamic niche in cancer progression.
Pengfei Lu, Valerie M Weaver, Zena Werb. J Cell Biol 2012
10

Collagen reorganization at the tumor-stromal interface facilitates local invasion.
Paolo P Provenzano, Kevin W Eliceiri, Jay M Campbell, David R Inman, John G White, Patricia J Keely. BMC Med 2006
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.