A citation-based method for searching scientific literature

A Phillip West, Gerald S Shadel. Nat Rev Immunol 2017
Times Cited: 284







List of co-cited articles
772 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Circulating mitochondrial DAMPs cause inflammatory responses to injury.
Qin Zhang, Mustafa Raoof, Yu Chen, Yuka Sumi, Tolga Sursal, Wolfgang Junger, Karim Brohi, Kiyoshi Itagaki, Carl J Hauser. Nature 2010
28

Mitochondrial DNA stress primes the antiviral innate immune response.
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
629
25

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,[...]. Nat Immunol 2011
20

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
999
17

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Zhenyu Zhong, Shuang Liang, Elsa Sanchez-Lopez, Feng He, Shabnam Shalapour, Xue-Jia Lin, Jerry Wong, Siyuan Ding, Ekihiro Seki, Bernd Schnabl,[...]. Nature 2018
273
14

Parkin and PINK1 mitigate STING-induced inflammation.
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
349
12

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.
Christian Lood, Luz P Blanco, Monica M Purmalek, Carmelo Carmona-Rivera, Suk S De Ravin, Carolyne K Smith, Harry L Malech, Jeffrey A Ledbetter, Keith B Elkon, Mariana J Kaplan. Nat Med 2016
545
12

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.
Jeonghan Kim, Rajeev Gupta, Luz P Blanco, Shutong Yang, Anna Shteinfer-Kuzmine, Kening Wang, Jun Zhu, Hee Eun Yoon, Xinghao Wang, Martijn Kerkhofs,[...]. Science 2019
70
17

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.
Kate McArthur, Lachlan W Whitehead, John M Heddleston, Lucy Li, Benjamin S Padman, Viola Oorschot, Niall D Geoghegan, Stephane Chappaz, Sophia Davidson, Hui San Chin,[...]. Science 2018
225
11

Mitochondria in innate immune responses.
A Phillip West, Gerald S Shadel, Sankar Ghosh. Nat Rev Immunol 2011
683
11

Mitochondrial DNA in inflammation and immunity.
Joel S Riley, Stephen Wg Tait. EMBO Rep 2020
69
15

Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Anthony Rongvaux, Ruaidhrí Jackson, Christian C D Harman, Tuo Li, A Phillip West, Marcel R de Zoete, Youtong Wu, Brian Yordy, Saquib A Lakhani, Chia-Yi Kuan,[...]. Cell 2014
346
10

Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus.
Simone Caielli, Shruti Athale, Bojana Domic, Elise Murat, Manjari Chandra, Romain Banchereau, Jeanine Baisch, Kate Phelps, Sandra Clayton, Mei Gong,[...]. J Exp Med 2016
186
10

Mitochondrial double-stranded RNA triggers antiviral signalling in humans.
Ashish Dhir, Somdutta Dhir, Lukasz S Borowski, Laura Jimenez, Michael Teitell, Agnès Rötig, Yanick J Crow, Gillian I Rice, Darragh Duffy, Christelle Tamby,[...]. Nature 2018
145
10

Mitochondria are the powerhouses of immunity.
Evanna L Mills, Beth Kelly, Luke A J O'Neill. Nat Immunol 2017
309
10

Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
Michael J White, Kate McArthur, Donald Metcalf, Rachael M Lane, John C Cambier, Marco J Herold, Mark F van Delft, Sammy Bedoui, Guillaume Lessene, Matthew E Ritchie,[...]. Cell 2014
386
9

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.
Takafumi Oka, Shungo Hikoso, Osamu Yamaguchi, Manabu Taneike, Toshihiro Takeda, Takahito Tamai, Jota Oyabu, Tomokazu Murakawa, Hiroyuki Nakayama, Kazuhiko Nishida,[...]. Nature 2012
623
9

Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses.
L Vincent Collins, Shahin Hajizadeh, Elisabeth Holme, Ing-Marie Jonsson, Andrej Tarkowski. J Leukoc Biol 2004
256
9


The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases.
Kiichi Nakahira, Shu Hisata, Augustine M K Choi. Antioxid Redox Signal 2015
110
9

A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
8

cGAS in action: Expanding roles in immunity and inflammation.
Andrea Ablasser, Zhijian J Chen. Science 2019
182
8

Mitochondrial diseases.
Gráinne S Gorman, Patrick F Chinnery, Salvatore DiMauro, Michio Hirano, Yasutoshi Koga, Robert McFarland, Anu Suomalainen, David R Thorburn, Massimo Zeviani, Douglass M Turnbull. Nat Rev Dis Primers 2016
387
8

Mitochondrial DNA Stress Signalling Protects the Nuclear Genome.
Zheng Wu, Sebastian Oeck, A Phillip West, Kailash C Mangalhara, Alva G Sainz, Laura E Newman, Xiao-Ou Zhang, Lizhen Wu, Qin Yan, Marcus Bosenberg,[...]. Nat Metab 2019
18
44

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis.
Joel S Riley, Giovanni Quarato, Catherine Cloix, Jonathan Lopez, Jim O'Prey, Matthew Pearson, James Chapman, Hiromi Sesaki, Leo M Carlin, João F Passos,[...]. EMBO J 2018
98
7

Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation.
Kiichi Nakahira, Sun-Young Kyung, Angela J Rogers, Lee Gazourian, Sojung Youn, Anthony F Massaro, Carolina Quintana, Juan C Osorio, Zhaoxi Wang, Yang Zhao,[...]. PLoS Med 2013
232
7

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
7

Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING.
Lauren D Aarreberg, Katharina Esser-Nobis, Connor Driscoll, Andrey Shuvarikov, Justin A Roby, Michael Gale. Mol Cell 2019
54
12

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis.
Ki Wung Chung, Poonam Dhillon, Shizheng Huang, Xin Sheng, Rojesh Shrestha, Chengxiang Qiu, Brett A Kaufman, Jihwan Park, Liming Pei, Joseph Baur,[...]. Cell Metab 2019
63
11

Mitochondrial TCA cycle metabolites control physiology and disease.
Inmaculada Martínez-Reyes, Navdeep S Chandel. Nat Commun 2020
180
7

Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
6


Neutrophil extracellular traps kill bacteria.
Volker Brinkmann, Ulrike Reichard, Christian Goosmann, Beatrix Fauler, Yvonne Uhlemann, David S Weiss, Yvette Weinrauch, Arturo Zychlinsky. Science 2004
6

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.
A Phillip West, Igor E Brodsky, Christoph Rahner, Dong Kyun Woo, Hediye Erdjument-Bromage, Paul Tempst, Matthew C Walsh, Yongwon Choi, Gerald S Shadel, Sankar Ghosh. Nature 2011
826
6

Pattern recognition receptors and inflammation.
Osamu Takeuchi, Shizuo Akira. Cell 2010
6

Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue.
Jian-Zheng Zhang, Zhi Liu, Jia Liu, Ji-Xin Ren, Tian-Sheng Sun. Int J Mol Med 2014
122
6

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
426
6

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
6

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging.
G C Kujoth, A Hiona, T D Pugh, S Someya, K Panzer, S E Wohlgemuth, T Hofer, A Y Seo, R Sullivan, W A Jobling,[...]. Science 2005
6

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.
Qi Chen, Lijun Sun, Zhijian J Chen. Nat Immunol 2016
615
5

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation.
Naeha Subramanian, Kannan Natarajan, Menna R Clatworthy, Ze Wang, Ronald N Germain. Cell 2013
343
5

Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury.
Mohammad Naimul Islam, Shonit R Das, Memet T Emin, Michelle Wei, Li Sun, Kristin Westphalen, David J Rowlands, Sadiqa K Quadri, Sunita Bhattacharya, Jahar Bhattacharya. Nat Med 2012
703
5

Degraded mitochondrial DNA is a newly identified subtype of the damage associated molecular pattern (DAMP) family and possible trigger of neurodegeneration.
Alex Mathew, Tara A Lindsley, Anna Sheridan, Devang L Bhoiwala, Shazaan F Hushmendy, Eric J Yager, Elizabeth A Ruggiero, Dana R Crawford. J Alzheimers Dis 2012
63
7

Mechanisms of mitophagy.
Richard J Youle, Derek P Narendra. Nat Rev Mol Cell Biol 2011
5

Mitochondrial permeability transition triggers the release of mtDNA fragments.
M Patrushev, V Kasymov, V Patrusheva, T Ushakova, V Gogvadze, A Gaziev. Cell Mol Life Sci 2004
65
7

Mitochondrial transcription factor A regulates mtDNA copy number in mammals.
Mats I Ekstrand, Maria Falkenberg, Anja Rantanen, Chan Bae Park, Martina Gaspari, Kjell Hultenby, Pierre Rustin, Claes M Gustafsson, Nils-Göran Larsson. Hum Mol Genet 2004
551
5

The source of cell-free mitochondrial DNA in trauma and potential therapeutic strategies.
Kabilan Thurairajah, Gabrielle Daisy Briggs, Zsolt Janos Balogh. Eur J Trauma Emerg Surg 2018
32
15


Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps.
S Yousefi, C Mihalache, E Kozlowski, I Schmid, H U Simon. Cell Death Differ 2009
461
5

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Edward T Chouchani, Victoria R Pell, Edoardo Gaude, Dunja Aksentijević, Stephanie Y Sundier, Ellen L Robb, Angela Logan, Sergiy M Nadtochiy, Emily N J Ord, Anthony C Smith,[...]. Nature 2014
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.