A citation-based method for searching scientific literature

A Phillip West, Gerald S Shadel. Nat Rev Immunol 2017
Times Cited: 387







List of co-cited articles
724 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Circulating mitochondrial DAMPs cause inflammatory responses to injury.
Qin Zhang, Mustafa Raoof, Yu Chen, Yuka Sumi, Tolga Sursal, Wolfgang Junger, Karim Brohi, Kiyoshi Itagaki, Carl J Hauser. Nature 2010
25

Mitochondrial DNA stress primes the antiviral innate immune response.
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
789
22

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,[...]. Nat Immunol 2011
21

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
18

Mitochondrial DNA in inflammation and immunity.
Joel S Riley, Stephen Wg Tait. EMBO Rep 2020
158
16

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.
Takafumi Oka, Shungo Hikoso, Osamu Yamaguchi, Manabu Taneike, Toshihiro Takeda, Takahito Tamai, Jota Oyabu, Tomokazu Murakawa, Hiroyuki Nakayama, Kazuhiko Nishida,[...]. Nature 2012
703
14

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.
Jeonghan Kim, Rajeev Gupta, Luz P Blanco, Shutong Yang, Anna Shteinfer-Kuzmine, Kening Wang, Jun Zhu, Hee Eun Yoon, Xinghao Wang, Martijn Kerkhofs,[...]. Science 2019
137
11

Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses.
L Vincent Collins, Shahin Hajizadeh, Elisabeth Holme, Ing-Marie Jonsson, Andrej Tarkowski. J Leukoc Biol 2004
298
10

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
10

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.
Christian Lood, Luz P Blanco, Monica M Purmalek, Carmelo Carmona-Rivera, Suk S De Ravin, Carolyne K Smith, Harry L Malech, Jeffrey A Ledbetter, Keith B Elkon, Mariana J Kaplan. Nat Med 2016
668
10

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis.
Joel S Riley, Giovanni Quarato, Catherine Cloix, Jonathan Lopez, Jim O'Prey, Matthew Pearson, James Chapman, Hiromi Sesaki, Leo M Carlin, João F Passos,[...]. EMBO J 2018
156
10

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.
Kate McArthur, Lachlan W Whitehead, John M Heddleston, Lucy Li, Benjamin S Padman, Viola Oorschot, Niall D Geoghegan, Stephane Chappaz, Sophia Davidson, Hui San Chin,[...]. Science 2018
307
10

Parkin and PINK1 mitigate STING-induced inflammation.
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
495
10

Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Anthony Rongvaux, Ruaidhrí Jackson, Christian C D Harman, Tuo Li, A Phillip West, Marcel R de Zoete, Youtong Wu, Brian Yordy, Saquib A Lakhani, Chia-Yi Kuan,[...]. Cell 2014
420
9

Mitochondria are the powerhouses of immunity.
Evanna L Mills, Beth Kelly, Luke A J O'Neill. Nat Immunol 2017
407
9

Mitochondrial DNA in the regulation of innate immune responses.
Chunju Fang, Xiawei Wei, Yuquan Wei. Protein Cell 2016
88
10

Mitochondria in innate immune responses.
A Phillip West, Gerald S Shadel, Sankar Ghosh. Nat Rev Immunol 2011
763
9

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Zhenyu Zhong, Shuang Liang, Elsa Sanchez-Lopez, Feng He, Shabnam Shalapour, Xue-Jia Lin, Jerry Wong, Siyuan Ding, Ekihiro Seki, Bernd Schnabl,[...]. Nature 2018
382
9


Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.
Selene Glück, Baptiste Guey, Muhammet Fatih Gulen, Katharina Wolter, Tae-Won Kang, Niklas Arndt Schmacke, Anne Bridgeman, Jan Rehwinkel, Lars Zender, Andrea Ablasser. Nat Cell Biol 2017
424
8

Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
Michael J White, Kate McArthur, Donald Metcalf, Rachael M Lane, John C Cambier, Marco J Herold, Mark F van Delft, Sammy Bedoui, Guillaume Lessene, Matthew E Ritchie,[...]. Cell 2014
459
8

Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue.
Jian-Zheng Zhang, Zhi Liu, Jia Liu, Ji-Xin Ren, Tian-Sheng Sun. Int J Mol Med 2014
141
8

A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
8

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
Chien-Hsiung Yu, Sophia Davidson, Cassandra R Harapas, James B Hilton, Michael J Mlodzianoski, Pawat Laohamonthonkul, Cynthia Louis, Ronnie Ren Jie Low, Jonas Moecking, Dominic De Nardo,[...]. Cell 2020
139
8


Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING.
Lauren D Aarreberg, Katharina Esser-Nobis, Connor Driscoll, Andrey Shuvarikov, Justin A Roby, Michael Gale. Mol Cell 2019
91
7

Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus.
Simone Caielli, Shruti Athale, Bojana Domic, Elise Murat, Manjari Chandra, Romain Banchereau, Jeanine Baisch, Kate Phelps, Sandra Clayton, Mei Gong,[...]. J Exp Med 2016
225
7


cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung. Nature 2013
787
7

Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann,[...]. Cell 2013
531
6

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
6

Structural basis of STING binding with and phosphorylation by TBK1.
Conggang Zhang, Guijun Shang, Xiang Gui, Xuewu Zhang, Xiao-Chen Bai, Zhijian J Chen. Nature 2019
222
6

DNA sensing by the cGAS-STING pathway in health and disease.
Mona Motwani, Scott Pesiridis, Katherine A Fitzgerald. Nat Rev Genet 2019
341
6

Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3.
Xiaohan Ning, Yutao Wang, Miao Jing, Mengyin Sha, Mengze Lv, Pengfei Gao, Rui Zhang, Xiaojun Huang, Ji-Ming Feng, Zhengfan Jiang. Mol Cell 2019
96
6

DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway.
Juli Bai, Christopher Cervantes, Juan Liu, Sijia He, Haiyan Zhou, Bilin Zhang, Huan Cai, Dongqing Yin, Derong Hu, Zhi Li,[...]. Proc Natl Acad Sci U S A 2017
93
6

ccf-mtDNA as a Potential Link Between the Brain and Immune System in Neuro-Immunological Disorders.
Stefano Gambardella, Fiona Limanaqi, Rosangela Ferese, Francesca Biagioni, Rosa Campopiano, Diego Centonze, Francesco Fornai. Front Immunol 2019
43
13

Mitochondrial TCA cycle metabolites control physiology and disease.
Inmaculada Martínez-Reyes, Navdeep S Chandel. Nat Commun 2020
417
6

Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
6

Sequence and organization of the human mitochondrial genome.
S Anderson, A T Bankier, B G Barrell, M H de Bruijn, A R Coulson, J Drouin, I C Eperon, D P Nierlich, B A Roe, F Sanger,[...]. Nature 1981
6

Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C.
Björn Ingelsson, Daniel Söderberg, Tobias Strid, Anita Söderberg, Ann-Charlotte Bergh, Vesa Loitto, Kourosh Lotfi, Mårten Segelmark, Giannis Spyrou, Anders Rosén. Proc Natl Acad Sci U S A 2018
61
8


Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis.
Ki Wung Chung, Poonam Dhillon, Shizheng Huang, Xin Sheng, Rojesh Shrestha, Chengxiang Qiu, Brett A Kaufman, Jihwan Park, Liming Pei, Joseph Baur,[...]. Cell Metab 2019
127
5

Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.
Xu Zhang, Heping Shi, Jiaxi Wu, Xuewu Zhang, Lijun Sun, Chuo Chen, Zhijian J Chen. Mol Cell 2013
538
5

Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9.
Irma Garcia-Martinez, Nicola Santoro, Yonglin Chen, Rafaz Hoque, Xinshou Ouyang, Sonia Caprio, Mark J Shlomchik, Robert Lee Coffman, Albert Candia, Wajahat Zafar Mehal. J Clin Invest 2016
252
5

Self-DNA Sensing in Lung Inflammatory Diseases.
Sulayman Benmerzoug, Bernhard Ryffel, Dieudonnée Togbe, Valerie F J Quesniaux. Trends Immunol 2019
24
20

cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
658
5

cGAS in action: Expanding roles in immunity and inflammation.
Andrea Ablasser, Zhijian J Chen. Science 2019
271
5

DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria.
Lisa S Shock, Prashant V Thakkar, Erica J Peterson, Richard G Moran, Shirley M Taylor. Proc Natl Acad Sci U S A 2011
338
5

Mitochondrial double-stranded RNA triggers antiviral signalling in humans.
Ashish Dhir, Somdutta Dhir, Lukasz S Borowski, Laura Jimenez, Michael Teitell, Agnès Rötig, Yanick J Crow, Gillian I Rice, Darragh Duffy, Christelle Tamby,[...]. Nature 2018
205
5

Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing.
Nadine Gehrke, Christina Mertens, Thomas Zillinger, Jörg Wenzel, Tobias Bald, Sabine Zahn, Thomas Tüting, Gunther Hartmann, Winfried Barchet. Immunity 2013
231
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.