P Hemachandra Reddy, Maria Manczak, XiangLing Yin. J Alzheimers Dis 2017
Times Cited: 56
Times Cited: 56
Times Cited
Times Co-cited
Similarity
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
60
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
50
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
41
Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
Seung Hyun Baek, So Jung Park, Jae In Jeong, Sung Hyun Kim, Jihoon Han, Jae Won Kyung, Sang-Ha Baik, Yuri Choi, Bo Youn Choi, Jin Su Park,[...]. J Neurosci 2017
Seung Hyun Baek, So Jung Park, Jae In Jeong, Sung Hyun Kim, Jihoon Han, Jae Won Kyung, Sang-Ha Baik, Yuri Choi, Bo Youn Choi, Jin Su Park,[...]. J Neurosci 2017
37
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
37
Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Maria Manczak, Ramesh Kandimalla, David Fry, Hiromi Sesaki, P Hemachandra Reddy. Hum Mol Genet 2016
Maria Manczak, Ramesh Kandimalla, David Fry, Hiromi Sesaki, P Hemachandra Reddy. Hum Mol Genet 2016
30
Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model.
Wenzhang Wang, Jun Yin, Xiaopin Ma, Fanpeng Zhao, Sandra L Siedlak, Zhenlian Wang, Sandy Torres, Hisashi Fujioka, Ying Xu, George Perry,[...]. Hum Mol Genet 2017
Wenzhang Wang, Jun Yin, Xiaopin Ma, Fanpeng Zhao, Sandra L Siedlak, Zhenlian Wang, Sandy Torres, Hisashi Fujioka, Ying Xu, George Perry,[...]. Hum Mol Genet 2017
28
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization.
Ann Cassidy-Stone, Jerry E Chipuk, Elena Ingerman, Cheng Song, Choong Yoo, Tomomi Kuwana, Mark J Kurth, Jared T Shaw, Jenny E Hinshaw, Douglas R Green,[...]. Dev Cell 2008
Ann Cassidy-Stone, Jerry E Chipuk, Elena Ingerman, Cheng Song, Choong Yoo, Tomomi Kuwana, Mark J Kurth, Jared T Shaw, Jenny E Hinshaw, Douglas R Green,[...]. Dev Cell 2008
26
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
26
A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.
Xin Qi, Nir Qvit, Yu-Chin Su, Daria Mochly-Rosen. J Cell Sci 2013
Xin Qi, Nir Qvit, Yu-Chin Su, Daria Mochly-Rosen. J Cell Sci 2013
25
Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2018
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2018
25
Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons.
Maria Manczak, Peizhong Mao, Marcus J Calkins, Anda Cornea, Arubala P Reddy, Michael P Murphy, Hazel H Szeto, Byung Park, P Hemachandra Reddy. J Alzheimers Dis 2010
Maria Manczak, Peizhong Mao, Marcus J Calkins, Anda Cornea, Arubala P Reddy, Michael P Murphy, Hazel H Szeto, Byung Park, P Hemachandra Reddy. J Alzheimers Dis 2010
23
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease.
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
23
Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
Ramesh Kandimalla, Maria Manczak, David Fry, Yeguvapalli Suneetha, Hiromi Sesaki, P Hemachandra Reddy. Hum Mol Genet 2016
Ramesh Kandimalla, Maria Manczak, David Fry, Yeguvapalli Suneetha, Hiromi Sesaki, P Hemachandra Reddy. Hum Mol Genet 2016
21
Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Ramesh Kandimalla, Maria Manczak, Xiangling Yin, Rui Wang, P Hemachandra Reddy. Hum Mol Genet 2018
Ramesh Kandimalla, Maria Manczak, Xiangling Yin, Rui Wang, P Hemachandra Reddy. Hum Mol Genet 2018
21
Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
P Hemachandra Reddy, XiangLing Yin, Maria Manczak, Subodh Kumar, Jangampalli Adi Pradeepkiran, Murali Vijayan, Arubala P Reddy. Hum Mol Genet 2018
P Hemachandra Reddy, XiangLing Yin, Maria Manczak, Subodh Kumar, Jangampalli Adi Pradeepkiran, Murali Vijayan, Arubala P Reddy. Hum Mol Genet 2018
21
Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics.
P Hemachandra Reddy, Raghav Tripathi, Quang Troung, Karuna Tirumala, Tejaswini P Reddy, Vishwanath Anekonda, Ulziibat P Shirendeb, Marcus J Calkins, Arubala P Reddy, Peizhong Mao,[...]. Biochim Biophys Acta 2012
P Hemachandra Reddy, Raghav Tripathi, Quang Troung, Karuna Tirumala, Tejaswini P Reddy, Vishwanath Anekonda, Ulziibat P Shirendeb, Marcus J Calkins, Arubala P Reddy, Peizhong Mao,[...]. Biochim Biophys Acta 2012
19
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model.
Heng Du, Lan Guo, Shiqiang Yan, Alexander A Sosunov, Guy M McKhann, Shirley ShiDu Yan. Proc Natl Acad Sci U S A 2010
Heng Du, Lan Guo, Shiqiang Yan, Alexander A Sosunov, Guy M McKhann, Shirley ShiDu Yan. Proc Natl Acad Sci U S A 2010
19
Synergistic Protective Effects of Mitochondrial Division Inhibitor 1 and Mitochondria-Targeted Small Peptide SS31 in Alzheimer's Disease.
P Hemachandra Reddy, Maria Manczak, XiangLing Yin, Arubala P Reddy. J Alzheimers Dis 2018
P Hemachandra Reddy, Maria Manczak, XiangLing Yin, Arubala P Reddy. J Alzheimers Dis 2018
26
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo.
Phillip M Rappold, Mei Cui, Jonathan C Grima, Rebecca Z Fan, Karen L de Mesy-Bentley, Linan Chen, Xiaoxi Zhuang, William J Bowers, Kim Tieu. Nat Commun 2014
Phillip M Rappold, Mei Cui, Jonathan C Grima, Rebecca Z Fan, Karen L de Mesy-Bentley, Linan Chen, Xiaoxi Zhuang, William J Bowers, Kim Tieu. Nat Commun 2014
17
The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species.
Evan A Bordt, Pascaline Clerc, Brian A Roelofs, Andrew J Saladino, László Tretter, Vera Adam-Vizi, Edward Cherok, Ahmed Khalil, Nagendra Yadava, Shealinna X Ge,[...]. Dev Cell 2017
Evan A Bordt, Pascaline Clerc, Brian A Roelofs, Andrew J Saladino, László Tretter, Vera Adam-Vizi, Edward Cherok, Ahmed Khalil, Nagendra Yadava, Shealinna X Ge,[...]. Dev Cell 2017
17
Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases.
P Hemachandra Reddy, Tejaswini P Reddy, Maria Manczak, Marcus J Calkins, Ulziibat Shirendeb, Peizhong Mao. Brain Res Rev 2011
P Hemachandra Reddy, Tejaswini P Reddy, Maria Manczak, Marcus J Calkins, Ulziibat Shirendeb, Peizhong Mao. Brain Res Rev 2011
17
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients.
Xinglong Wang, Bo Su, Hisashi Fujioka, Xiongwei Zhu. Am J Pathol 2008
Xinglong Wang, Bo Su, Hisashi Fujioka, Xiongwei Zhu. Am J Pathol 2008
17
17
Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.
Ulziibat P Shirendeb, Marcus J Calkins, Maria Manczak, Vishwanath Anekonda, Brett Dufour, Jodi L McBride, Peizhong Mao, P Hemachandra Reddy. Hum Mol Genet 2012
Ulziibat P Shirendeb, Marcus J Calkins, Maria Manczak, Vishwanath Anekonda, Brett Dufour, Jodi L McBride, Peizhong Mao, P Hemachandra Reddy. Hum Mol Genet 2012
17
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
17
Mitochondrial division inhibitor 1 protects against mutant huntingtin-induced abnormal mitochondrial dynamics and neuronal damage in Huntington's disease.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2015
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2015
18
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
16
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
Hsiuchen Chen, Scott A Detmer, Andrew J Ewald, Erik E Griffin, Scott E Fraser, David C Chan. J Cell Biol 2003
16
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.
Ulziibat Shirendeb, Arubala P Reddy, Maria Manczak, Marcus J Calkins, Peizhong Mao, Danilo A Tagle, P Hemachandra Reddy. Hum Mol Genet 2011
Ulziibat Shirendeb, Arubala P Reddy, Maria Manczak, Marcus J Calkins, Peizhong Mao, Danilo A Tagle, P Hemachandra Reddy. Hum Mol Genet 2011
16
Mitochondrial medicine for aging and neurodegenerative diseases.
P Hemachandra Reddy. Neuromolecular Med 2008
P Hemachandra Reddy. Neuromolecular Med 2008
16
Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
14
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
14
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.
Michael T Lin, M Flint Beal. Nature 2006
Michael T Lin, M Flint Beal. Nature 2006
14
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury.
Dong-Hyung Cho, Tomohiro Nakamura, Jianguo Fang, Piotr Cieplak, Adam Godzik, Zezong Gu, Stuart A Lipton. Science 2009
Dong-Hyung Cho, Tomohiro Nakamura, Jianguo Fang, Piotr Cieplak, Adam Godzik, Zezong Gu, Stuart A Lipton. Science 2009
14
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.
Wenjun Song, Jin Chen, Alejandra Petrilli, Geraldine Liot, Eva Klinglmayr, Yue Zhou, Patrick Poquiz, Jonathan Tjong, Mahmoud A Pouladi, Michael R Hayden,[...]. Nat Med 2011
Wenjun Song, Jin Chen, Alejandra Petrilli, Geraldine Liot, Eva Klinglmayr, Yue Zhou, Patrick Poquiz, Jonathan Tjong, Mahmoud A Pouladi, Michael R Hayden,[...]. Nat Med 2011
14
Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease.
Amit U Joshi, Nay L Saw, Mehrdad Shamloo, Daria Mochly-Rosen. Oncotarget 2017
Amit U Joshi, Nay L Saw, Mehrdad Shamloo, Daria Mochly-Rosen. Oncotarget 2017
14
Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP.
Emily Filichia, Barry Hoffer, Xin Qi, Yu Luo. Sci Rep 2016
Emily Filichia, Barry Hoffer, Xin Qi, Yu Luo. Sci Rep 2016
14
Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell.
Xueqi Gan, Shengbin Huang, Long Wu, Yongfu Wang, Gang Hu, Guangyue Li, Hongju Zhang, Haiyang Yu, Russell Howard Swerdlow, John Xi Chen,[...]. Biochim Biophys Acta 2014
Xueqi Gan, Shengbin Huang, Long Wu, Yongfu Wang, Gang Hu, Guangyue Li, Hongju Zhang, Haiyang Yu, Russell Howard Swerdlow, John Xi Chen,[...]. Biochim Biophys Acta 2014
12
Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration.
Xing Guo, Marie-Helene Disatnik, Marie Monbureau, Mehrdad Shamloo, Daria Mochly-Rosen, Xin Qi. J Clin Invest 2013
Xing Guo, Marie-Helene Disatnik, Marie Monbureau, Mehrdad Shamloo, Daria Mochly-Rosen, Xin Qi. J Clin Invest 2013
12
The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice.
Junko Wakabayashi, Zhongyan Zhang, Nobunao Wakabayashi, Yasushi Tamura, Masahiro Fukaya, Thomas W Kensler, Miho Iijima, Hiromi Sesaki. J Cell Biol 2009
Junko Wakabayashi, Zhongyan Zhang, Nobunao Wakabayashi, Yasushi Tamura, Masahiro Fukaya, Thomas W Kensler, Miho Iijima, Hiromi Sesaki. J Cell Biol 2009
12
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease.
Heng Du, Lan Guo, Fang Fang, Doris Chen, Alexander A Sosunov, Guy M McKhann, Yilin Yan, Chunyu Wang, Hong Zhang, Jeffery D Molkentin,[...]. Nat Med 2008
Heng Du, Lan Guo, Fang Fang, Doris Chen, Alexander A Sosunov, Guy M McKhann, Yilin Yan, Chunyu Wang, Hong Zhang, Jeffery D Molkentin,[...]. Nat Med 2008
12
Dynasore, a cell-permeable inhibitor of dynamin.
Eric Macia, Marcelo Ehrlich, Ramiro Massol, Emmanuel Boucrot, Christian Brunner, Tomas Kirchhausen. Dev Cell 2006
Eric Macia, Marcelo Ehrlich, Ramiro Massol, Emmanuel Boucrot, Christian Brunner, Tomas Kirchhausen. Dev Cell 2006
12
Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease.
P Hemachandra Reddy. Brain Res 2011
P Hemachandra Reddy. Brain Res 2011
12
Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis.
Ramesh Kandimalla, P Hemachandra Reddy. Biochim Biophys Acta 2016
Ramesh Kandimalla, P Hemachandra Reddy. Biochim Biophys Acta 2016
12
Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.
Casper Caspersen, Ning Wang, Jun Yao, Alexander Sosunov, Xi Chen, Joyce W Lustbader, Hong Wei Xu, David Stern, Guy McKhann, Shi Du Yan. FASEB J 2005
Casper Caspersen, Ning Wang, Jun Yao, Alexander Sosunov, Xi Chen, Joyce W Lustbader, Hong Wei Xu, David Stern, Guy McKhann, Shi Du Yan. FASEB J 2005
12
Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease.
P Hemachandra Reddy, Shannon McWeeney, Byung S Park, Maria Manczak, Ramana V Gutala, Dara Partovi, Youngsin Jung, Vincent Yau, Robert Searles, Motomi Mori,[...]. Hum Mol Genet 2004
P Hemachandra Reddy, Shannon McWeeney, Byung S Park, Maria Manczak, Ramana V Gutala, Dara Partovi, Youngsin Jung, Vincent Yau, Robert Searles, Motomi Mori,[...]. Hum Mol Genet 2004
12
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.
Xiongwei Zhu, George Perry, Mark A Smith, Xinglong Wang. J Alzheimers Dis 2013
Xiongwei Zhu, George Perry, Mark A Smith, Xinglong Wang. J Alzheimers Dis 2013
12
Mitochondrial abnormalities in Alzheimer's disease.
K Hirai, G Aliev, A Nunomura, H Fujioka, R L Russell, C S Atwood, A B Johnson, Y Kress, H V Vinters, M Tabaton,[...]. J Neurosci 2001
K Hirai, G Aliev, A Nunomura, H Fujioka, R L Russell, C S Atwood, A B Johnson, Y Kress, H V Vinters, M Tabaton,[...]. J Neurosci 2001
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.