Annabel Romero-Hernandez, Hiro Furukawa. Mol Pharmacol 2017
Times Cited: 17
Times Cited: 17
Times Cited
Times Co-cited
Similarity
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease.
Pierre Paoletti, Camilla Bellone, Qiang Zhou. Nat Rev Neurosci 2013
Pierre Paoletti, Camilla Bellone, Qiang Zhou. Nat Rev Neurosci 2013
82
Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.
David H Hackos, Patrick J Lupardus, Teddy Grand, Yelin Chen, Tzu-Ming Wang, Paul Reynen, Amy Gustafson, Heidi J A Wallweber, Matthew Volgraf, Benjamin D Sellers,[...]. Neuron 2016
David H Hackos, Patrick J Lupardus, Teddy Grand, Yelin Chen, Tzu-Ming Wang, Paul Reynen, Amy Gustafson, Heidi J A Wallweber, Matthew Volgraf, Benjamin D Sellers,[...]. Neuron 2016
70
Structural insights into competitive antagonism in NMDA receptors.
Annie Jespersen, Nami Tajima, Gabriela Fernandez-Cuervo, Ethel C Garnier-Amblard, Hiro Furukawa. Neuron 2014
Annie Jespersen, Nami Tajima, Gabriela Fernandez-Cuervo, Ethel C Garnier-Amblard, Hiro Furukawa. Neuron 2014
70
Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.
Feng Yi, Tung-Chung Mou, Katherine N Dorsett, Robert A Volkmann, Frank S Menniti, Stephen R Sprang, Kasper B Hansen. Neuron 2016
Feng Yi, Tung-Chung Mou, Katherine N Dorsett, Robert A Volkmann, Frank S Menniti, Stephen R Sprang, Kasper B Hansen. Neuron 2016
64
Glutamate receptor ion channels: structure, regulation, and function.
Stephen F Traynelis, Lonnie P Wollmuth, Chris J McBain, Frank S Menniti, Katie M Vance, Kevin K Ogden, Kasper B Hansen, Hongjie Yuan, Scott J Myers, Ray Dingledine. Pharmacol Rev 2010
Stephen F Traynelis, Lonnie P Wollmuth, Chris J McBain, Frank S Menniti, Katie M Vance, Kevin K Ogden, Kasper B Hansen, Hongjie Yuan, Scott J Myers, Ray Dingledine. Pharmacol Rev 2010
64
Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits.
Genevieve E Lind, Tung-Chung Mou, Lucia Tamborini, Martin G Pomper, Carlo De Micheli, Paola Conti, Andrea Pinto, Kasper B Hansen. Proc Natl Acad Sci U S A 2017
Genevieve E Lind, Tung-Chung Mou, Lucia Tamborini, Martin G Pomper, Carlo De Micheli, Paola Conti, Andrea Pinto, Kasper B Hansen. Proc Natl Acad Sci U S A 2017
64
Crystal structure of a heterotetrameric NMDA receptor ion channel.
Erkan Karakas, Hiro Furukawa. Science 2014
Erkan Karakas, Hiro Furukawa. Science 2014
58
Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core.
Hiroyasu Furukawa, Eric Gouaux. EMBO J 2003
Hiroyasu Furukawa, Eric Gouaux. EMBO J 2003
58
Subunit arrangement and function in NMDA receptors.
Hiroyasu Furukawa, Satinder K Singh, Romina Mancusso, Eric Gouaux. Nature 2005
Hiroyasu Furukawa, Satinder K Singh, Romina Mancusso, Eric Gouaux. Nature 2005
58
Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Annabel Romero-Hernandez, Noriko Simorowski, Erkan Karakas, Hiro Furukawa. Neuron 2016
Annabel Romero-Hernandez, Noriko Simorowski, Erkan Karakas, Hiro Furukawa. Neuron 2016
58
NMDA receptor structures reveal subunit arrangement and pore architecture.
Chia-Hsueh Lee, Wei Lü, Jennifer Carlisle Michel, April Goehring, Juan Du, Xianqiang Song, Eric Gouaux. Nature 2014
Chia-Hsueh Lee, Wei Lü, Jennifer Carlisle Michel, April Goehring, Juan Du, Xianqiang Song, Eric Gouaux. Nature 2014
52
Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors.
Kasper B Hansen, Nami Tajima, Rune Risgaard, Riley E Perszyk, Lars Jørgensen, Katie M Vance, Kevin K Ogden, Rasmus P Clausen, Hiro Furukawa, Stephen F Traynelis. Mol Pharmacol 2013
Kasper B Hansen, Nami Tajima, Rune Risgaard, Riley E Perszyk, Lars Jørgensen, Katie M Vance, Kevin K Ogden, Rasmus P Clausen, Hiro Furukawa, Stephen F Traynelis. Mol Pharmacol 2013
52
Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.
Wei Lü, Juan Du, April Goehring, Eric Gouaux. Science 2017
Wei Lü, Juan Du, April Goehring, Eric Gouaux. Science 2017
52
Activation of NMDA receptors and the mechanism of inhibition by ifenprodil.
Nami Tajima, Erkan Karakas, Timothy Grant, Noriko Simorowski, Ruben Diaz-Avalos, Nikolaus Grigorieff, Hiro Furukawa. Nature 2016
Nami Tajima, Erkan Karakas, Timothy Grant, Noriko Simorowski, Ruben Diaz-Avalos, Nikolaus Grigorieff, Hiro Furukawa. Nature 2016
52
Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Katie M Vance, Noriko Simorowski, Stephen F Traynelis, Hiro Furukawa. Nat Commun 2011
Katie M Vance, Noriko Simorowski, Stephen F Traynelis, Hiro Furukawa. Nat Commun 2011
52
Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Erkan Karakas, Noriko Simorowski, Hiro Furukawa. Nature 2011
Erkan Karakas, Noriko Simorowski, Hiro Furukawa. Nature 2011
52
Developmental and regional expression in the rat brain and functional properties of four NMDA receptors.
H Monyer, N Burnashev, D J Laurie, B Sakmann, P H Seeburg. Neuron 1994
H Monyer, N Burnashev, D J Laurie, B Sakmann, P H Seeburg. Neuron 1994
47
Mechanism of partial agonist action at the NR1 subunit of NMDA receptors.
Atsushi Inanobe, Hiroyasu Furukawa, Eric Gouaux. Neuron 2005
Atsushi Inanobe, Hiroyasu Furukawa, Eric Gouaux. Neuron 2005
47
Distinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors.
Kasper B Hansen, Kevin K Ogden, Hongjie Yuan, Stephen F Traynelis. Neuron 2014
Kasper B Hansen, Kevin K Ogden, Hongjie Yuan, Stephen F Traynelis. Neuron 2014
41
Conformational analysis of NMDA receptor GluN1, GluN2, and GluN3 ligand-binding domains reveals subtype-specific characteristics.
Yongneng Yao, John Belcher, Anthony J Berger, Mark L Mayer, Albert Y Lau. Structure 2013
Yongneng Yao, John Belcher, Anthony J Berger, Mark L Mayer, Albert Y Lau. Structure 2013
41
Mechanism of NMDA Receptor Inhibition and Activation.
Shujia Zhu, Richard A Stein, Craig Yoshioka, Chia-Hsueh Lee, April Goehring, Hassane S Mchaourab, Eric Gouaux. Cell 2016
Shujia Zhu, Richard A Stein, Craig Yoshioka, Chia-Hsueh Lee, April Goehring, Hassane S Mchaourab, Eric Gouaux. Cell 2016
41
Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.
Matthew Volgraf, Benjamin D Sellers, Yu Jiang, Guosheng Wu, Cuong Q Ly, Elisia Villemure, Richard M Pastor, Po-wai Yuen, Aijun Lu, Xifeng Luo,[...]. J Med Chem 2016
Matthew Volgraf, Benjamin D Sellers, Yu Jiang, Guosheng Wu, Cuong Q Ly, Elisia Villemure, Richard M Pastor, Po-wai Yuen, Aijun Lu, Xifeng Luo,[...]. J Med Chem 2016
41
Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Michael C Regan, Timothy Grant, Miranda J McDaniel, Erkan Karakas, Jing Zhang, Stephen F Traynelis, Nikolaus Grigorieff, Hiro Furukawa. Neuron 2018
Michael C Regan, Timothy Grant, Miranda J McDaniel, Erkan Karakas, Jing Zhang, Stephen F Traynelis, Nikolaus Grigorieff, Hiro Furukawa. Neuron 2018
41
Structure, function, and allosteric modulation of NMDA receptors.
Kasper B Hansen, Feng Yi, Riley E Perszyk, Hiro Furukawa, Lonnie P Wollmuth, Alasdair J Gibb, Stephen F Traynelis. J Gen Physiol 2018
Kasper B Hansen, Feng Yi, Riley E Perszyk, Hiro Furukawa, Lonnie P Wollmuth, Alasdair J Gibb, Stephen F Traynelis. J Gen Physiol 2018
41
5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition.
Yves P Auberson, Hans Allgeier, Serge Bischoff, Kurt Lingenhoehl, Robert Moretti, Markus Schmutz. Bioorg Med Chem Lett 2002
Yves P Auberson, Hans Allgeier, Serge Bischoff, Kurt Lingenhoehl, Robert Moretti, Markus Schmutz. Bioorg Med Chem Lett 2002
35
Control of NMDA receptor function by the NR2 subunit amino-terminal domain.
Hongjie Yuan, Kasper B Hansen, Katie M Vance, Kevin K Ogden, Stephen F Traynelis. J Neurosci 2009
Hongjie Yuan, Kasper B Hansen, Katie M Vance, Kevin K Ogden, Stephen F Traynelis. J Neurosci 2009
35
Changing subunit composition of heteromeric NMDA receptors during development of rat cortex.
M Sheng, J Cummings, L A Roldan, Y N Jan, L Y Jan. Nature 1994
M Sheng, J Cummings, L A Roldan, Y N Jan, L Y Jan. Nature 1994
35
Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy.
Wenjuan Chen, Anel Tankovic, Pieter B Burger, Hirofumi Kusumoto, Stephen F Traynelis, Hongjie Yuan. Mol Pharmacol 2017
Wenjuan Chen, Anel Tankovic, Pieter B Burger, Hirofumi Kusumoto, Stephen F Traynelis, Hongjie Yuan. Mol Pharmacol 2017
35
A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists.
David Stroebel, Derek L Buhl, John D Knafels, Pranab K Chanda, Michael Green, Simone Sciabola, Laetitia Mony, Pierre Paoletti, Jayvardhan Pandit. Mol Pharmacol 2016
David Stroebel, Derek L Buhl, John D Knafels, Pranab K Chanda, Michael Green, Simone Sciabola, Laetitia Mony, Pierre Paoletti, Jayvardhan Pandit. Mol Pharmacol 2016
35
Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors.
Yongneng Yao, Chris B Harrison, Peter L Freddolino, Klaus Schulten, Mark L Mayer. EMBO J 2008
Yongneng Yao, Chris B Harrison, Peter L Freddolino, Klaus Schulten, Mark L Mayer. EMBO J 2008
35
Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit.
Erkan Karakas, Noriko Simorowski, Hiro Furukawa. EMBO J 2009
Erkan Karakas, Noriko Simorowski, Hiro Furukawa. EMBO J 2009
35
Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors.
Jin-Bao Zhang, Shenghai Chang, Pan Xu, Miao Miao, Hangjun Wu, Youyi Zhang, Tongtong Zhang, Han Wang, Jilin Zhang, Chun Xie,[...]. Cell Rep 2018
Jin-Bao Zhang, Shenghai Chang, Pan Xu, Miao Miao, Hangjun Wu, Youyi Zhang, Tongtong Zhang, Han Wang, Jilin Zhang, Chun Xie,[...]. Cell Rep 2018
35
Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor.
Farzad Jalali-Yazdi, Sandipan Chowdhury, Craig Yoshioka, Eric Gouaux. Cell 2018
Farzad Jalali-Yazdi, Sandipan Chowdhury, Craig Yoshioka, Eric Gouaux. Cell 2018
35
Equilibrium constants for (R)-[(S)-1-(4-bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic acid (NVP-AAM077) acting at recombinant NR1/NR2A and NR1/NR2B N-methyl-D-aspartate receptors: Implications for studies of synaptic transmission.
Pamela A Frizelle, Philip E Chen, David J A Wyllie. Mol Pharmacol 2006
Pamela A Frizelle, Philip E Chen, David J A Wyllie. Mol Pharmacol 2006
29
Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator.
Alpa Khatri, Pieter B Burger, Sharon A Swanger, Kasper B Hansen, Sommer Zimmerman, Erkan Karakas, Dennis C Liotta, Hiro Furukawa, James P Snyder, Stephen F Traynelis. Mol Pharmacol 2014
Alpa Khatri, Pieter B Burger, Sharon A Swanger, Kasper B Hansen, Sommer Zimmerman, Erkan Karakas, Dennis C Liotta, Hiro Furukawa, James P Snyder, Stephen F Traynelis. Mol Pharmacol 2014
29
Reduced curvature of ligand-binding domain free-energy surface underlies partial agonism at NMDA receptors.
Jian Dai, Huan-Xiang Zhou. Structure 2015
Jian Dai, Huan-Xiang Zhou. Structure 2015
29
Mechanical coupling maintains the fidelity of NMDA receptor-mediated currents.
Rashek Kazi, Jian Dai, Cameron Sweeney, Huan-Xiang Zhou, Lonnie P Wollmuth. Nat Neurosci 2014
Rashek Kazi, Jian Dai, Cameron Sweeney, Huan-Xiang Zhou, Lonnie P Wollmuth. Nat Neurosci 2014
29
GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile.
Elisia Villemure, Matthew Volgraf, Yu Jiang, Guosheng Wu, Cuong Q Ly, Po-Wai Yuen, Aijun Lu, Xifeng Luo, Mingcui Liu, Shun Zhang,[...]. ACS Med Chem Lett 2016
Elisia Villemure, Matthew Volgraf, Yu Jiang, Guosheng Wu, Cuong Q Ly, Po-Wai Yuen, Aijun Lu, Xifeng Luo, Mingcui Liu, Shun Zhang,[...]. ACS Med Chem Lett 2016
29
Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones.
M L Mayer, G L Westbrook, P B Guthrie. Nature 1984
M L Mayer, G L Westbrook, P B Guthrie. Nature 1984
29
Mechanism of NMDA receptor channel block by MK-801 and memantine.
Xianqiang Song, Morten Ø Jensen, Vishwanath Jogini, Richard A Stein, Chia-Hsueh Lee, Hassane S Mchaourab, David E Shaw, Eric Gouaux. Nature 2018
Xianqiang Song, Morten Ø Jensen, Vishwanath Jogini, Richard A Stein, Chia-Hsueh Lee, Hassane S Mchaourab, David E Shaw, Eric Gouaux. Nature 2018
29
Mechanism of differential control of NMDA receptor activity by NR2 subunits.
Marc Gielen, Beth Siegler Retchless, Laetitia Mony, Jon W Johnson, Pierre Paoletti. Nature 2009
Marc Gielen, Beth Siegler Retchless, Laetitia Mony, Jon W Johnson, Pierre Paoletti. Nature 2009
29
Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats.
C Akazawa, R Shigemoto, Y Bessho, S Nakanishi, N Mizuno. J Comp Neurol 1994
C Akazawa, R Shigemoto, Y Bessho, S Nakanishi, N Mizuno. J Comp Neurol 1994
29
Emerging structural insights into the function of ionotropic glutamate receptors.
Erkan Karakas, Michael C Regan, Hiro Furukawa. Trends Biochem Sci 2015
Erkan Karakas, Michael C Regan, Hiro Furukawa. Trends Biochem Sci 2015
29
Identification and characterization of novel NMDA receptor antagonists selective for NR2A- over NR2B-containing receptors.
Ezio Bettini, Anna Sava, Cristiana Griffante, Corrado Carignani, Alberto Buson, Anna Maria Capelli, Michele Negri, Filippo Andreetta, Sergio A Senar-Sancho, Lorena Guiral,[...]. J Pharmacol Exp Ther 2010
Ezio Bettini, Anna Sava, Cristiana Griffante, Corrado Carignani, Alberto Buson, Anna Maria Capelli, Michele Negri, Filippo Andreetta, Sergio A Senar-Sancho, Lorena Guiral,[...]. J Pharmacol Exp Ther 2010
29
Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors.
Michael C Regan, Zongjian Zhu, Hongjie Yuan, Scott J Myers, Dave S Menaldino, Yesim A Tahirovic, Dennis C Liotta, Stephen F Traynelis, Hiro Furukawa. Nat Commun 2019
Michael C Regan, Zongjian Zhu, Hongjie Yuan, Scott J Myers, Dave S Menaldino, Yesim A Tahirovic, Dennis C Liotta, Stephen F Traynelis, Hiro Furukawa. Nat Commun 2019
29
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Paul D Adams, Pavel V Afonine, Gábor Bunkóczi, Vincent B Chen, Ian W Davis, Nathaniel Echols, Jeffrey J Headd, Li-Wei Hung, Gary J Kapral, Ralf W Grosse-Kunstleve,[...]. Acta Crystallogr D Biol Crystallogr 2010
Paul D Adams, Pavel V Afonine, Gábor Bunkóczi, Vincent B Chen, Ian W Davis, Nathaniel Echols, Jeffrey J Headd, Li-Wei Hung, Gary J Kapral, Ralf W Grosse-Kunstleve,[...]. Acta Crystallogr D Biol Crystallogr 2010
23
[20] Processing of X-ray diffraction data collected in oscillation mode.
Zbyszek Otwinowski, Wladek Minor. Methods Enzymol 1997
Zbyszek Otwinowski, Wladek Minor. Methods Enzymol 1997
23
MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.
Robert A Volkmann, Christopher M Fanger, David R Anderson, Venkata Ramana Sirivolu, Kathy Paschetto, Earl Gordon, Caterina Virginio, Melanie Gleyzes, Bruno Buisson, Esther Steidl,[...]. PLoS One 2016
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23
The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B).
J Luo, Y Wang, R P Yasuda, A W Dunah, B B Wolfe. Mol Pharmacol 1997
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23
Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site.
Trine Kvist, Thomas Bielefeldt Steffensen, Jeremy R Greenwood, Fatemeh Mehrzad Tabrizi, Kasper B Hansen, Michael Gajhede, Darryl S Pickering, Stephen F Traynelis, Jette Sandholm Kastrup, Hans Bräuner-Osborne. J Biol Chem 2013
Trine Kvist, Thomas Bielefeldt Steffensen, Jeremy R Greenwood, Fatemeh Mehrzad Tabrizi, Kasper B Hansen, Michael Gajhede, Darryl S Pickering, Stephen F Traynelis, Jette Sandholm Kastrup, Hans Bräuner-Osborne. J Biol Chem 2013
26
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.