Pete A Williams, Jeffrey M Harder, Nicole E Foxworth, Brynn H Cardozo, Kelly E Cochran, Simon W M John. Front Neurosci 2017
Times Cited: 44
Times Cited: 44
Times Cited
Times Co-cited
Similarity
Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice.
Pete A Williams, Jeffrey M Harder, Nicole E Foxworth, Kelly E Cochran, Vivek M Philip, Vittorio Porciatti, Oliver Smithies, Simon W M John. Science 2017
Pete A Williams, Jeffrey M Harder, Nicole E Foxworth, Kelly E Cochran, Vivek M Philip, Vittorio Porciatti, Oliver Smithies, Simon W M John. Science 2017
70
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma.
Gareth R Howell, Richard T Libby, Tatjana C Jakobs, Richard S Smith, F Campbell Phalan, Joseph W Barter, Jessica M Barbay, Jeffrey K Marchant, Nagaraju Mahesh, Vittorio Porciatti,[...]. J Cell Biol 2007
Gareth R Howell, Richard T Libby, Tatjana C Jakobs, Richard S Smith, F Campbell Phalan, Joseph W Barter, Jessica M Barbay, Jeffrey K Marchant, Nagaraju Mahesh, Vittorio Porciatti,[...]. J Cell Biol 2007
52
Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons.
Jonathan Gilley, Michael P Coleman. PLoS Biol 2010
Jonathan Gilley, Michael P Coleman. PLoS Biol 2010
38
The WldS gene delays axonal but not somatic degeneration in a rat glaucoma model.
Bogdan Beirowski, Elisabetta Babetto, Michael P Coleman, Keith R Martin. Eur J Neurosci 2008
Bogdan Beirowski, Elisabetta Babetto, Michael P Coleman, Keith R Martin. Eur J Neurosci 2008
36
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.
T G Mack, M Reiner, B Beirowski, W Mi, M Emanuelli, D Wagner, D Thomson, T Gillingwater, F Court, L Conforti,[...]. Nat Neurosci 2001
T G Mack, M Reiner, B Beirowski, W Mi, M Emanuelli, D Wagner, D Thomson, T Gillingwater, F Court, L Conforti,[...]. Nat Neurosci 2001
34
Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.
Yih-Chung Tham, Xiang Li, Tien Y Wong, Harry A Quigley, Tin Aung, Ching-Yu Cheng. Ophthalmology 2014
Yih-Chung Tham, Xiang Li, Tien Y Wong, Harry A Quigley, Tin Aung, Ching-Yu Cheng. Ophthalmology 2014
34
Oxidative stress and mitochondrial dysfunction in glaucoma.
Vicki Chrysostomou, Fatemeh Rezania, Ian A Trounce, Jonathan G Crowston. Curr Opin Pharmacol 2013
Vicki Chrysostomou, Fatemeh Rezania, Ian A Trounce, Jonathan G Crowston. Curr Opin Pharmacol 2013
31
Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.
Jeffrey M Harder, Catherine E Braine, Pete A Williams, Xianjun Zhu, Katharine H MacNicoll, Gregory L Sousa, Rebecca A Buchanan, Richard S Smith, Richard T Libby, Gareth R Howell,[...]. Proc Natl Acad Sci U S A 2017
Jeffrey M Harder, Catherine E Braine, Pete A Williams, Xianjun Zhu, Katharine H MacNicoll, Gregory L Sousa, Rebecca A Buchanan, Richard S Smith, Richard T Libby, Gareth R Howell,[...]. Proc Natl Acad Sci U S A 2017
31
Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma.
Pete A Williams, Jeffrey M Harder, Simon W M John. J Glaucoma 2017
Pete A Williams, Jeffrey M Harder, Simon W M John. J Glaucoma 2017
38
Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.
Kimberly A Fernandes, Katherine L Mitchell, Amit Patel, Olivia J Marola, Peter Shrager, Donald J Zack, Richard T Libby, Derek S Welsbie. Exp Eye Res 2018
Kimberly A Fernandes, Katherine L Mitchell, Amit Patel, Olivia J Marola, Peter Shrager, Donald J Zack, Richard T Libby, Derek S Welsbie. Exp Eye Res 2018
40
Wallerian degeneration: an emerging axon death pathway linking injury and disease.
Laura Conforti, Jonathan Gilley, Michael P Coleman. Nat Rev Neurosci 2014
Laura Conforti, Jonathan Gilley, Michael P Coleman. Nat Rev Neurosci 2014
29
Protection of mouse retinal ganglion cell axons and soma from glaucomatous and ischemic injury by cytoplasmic overexpression of Nmnat1.
Yanli Zhu, Lihong Zhang, Yo Sasaki, Jeffrey Milbrandt, Jeffrey M Gidday. Invest Ophthalmol Vis Sci 2013
Yanli Zhu, Lihong Zhang, Yo Sasaki, Jeffrey Milbrandt, Jeffrey M Gidday. Invest Ophthalmol Vis Sci 2013
27
Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage.
Richard T Libby, Yan Li, Olga V Savinova, Joseph Barter, Richard S Smith, Robert W Nickells, Simon W M John. PLoS Genet 2005
Richard T Libby, Yan Li, Olga V Savinova, Joseph Barter, Richard S Smith, Robert W Nickells, Simon W M John. PLoS Genet 2005
27
SARM1 activation triggers axon degeneration locally via NAD⁺ destruction.
Josiah Gerdts, E J Brace, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt. Science 2015
Josiah Gerdts, E J Brace, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt. Science 2015
27
Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma.
Pete A Williams, James R Tribble, Keating W Pepper, Stephen D Cross, B Paul Morgan, James E Morgan, Simon W M John, Gareth R Howell. Mol Neurodegener 2016
Pete A Williams, James R Tribble, Keating W Pepper, Stephen D Cross, B Paul Morgan, James E Morgan, Simon W M John, Gareth R Howell. Mol Neurodegener 2016
25
Transgenic mice expressing the Nmnat1 protein manifest robust delay in axonal degeneration in vivo.
Yo Sasaki, Bhupinder P S Vohra, Robert H Baloh, Jeffrey Milbrandt. J Neurosci 2009
Yo Sasaki, Bhupinder P S Vohra, Robert H Baloh, Jeffrey Milbrandt. J Neurosci 2009
25
Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve.
E R Lunn, V H Perry, M C Brown, H Rosen, S Gordon. Eur J Neurosci 1989
E R Lunn, V H Perry, M C Brown, H Rosen, S Gordon. Eur J Neurosci 1989
25
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.
Toshiyuki Araki, Yo Sasaki, Jeffrey Milbrandt. Science 2004
Toshiyuki Araki, Yo Sasaki, Jeffrey Milbrandt. Science 2004
25
The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration.
Kow Essuman, Daniel W Summers, Yo Sasaki, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt. Neuron 2017
Kow Essuman, Daniel W Summers, Yo Sasaki, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt. Neuron 2017
25
A local mechanism mediates NAD-dependent protection of axon degeneration.
Jing Wang, Qiwei Zhai, Ying Chen, Estelle Lin, Wei Gu, Michael W McBurney, Zhigang He. J Cell Biol 2005
Jing Wang, Qiwei Zhai, Ying Chen, Estelle Lin, Wei Gu, Michael W McBurney, Zhigang He. J Cell Biol 2005
25
Pathological axonal death through a MAPK cascade that triggers a local energy deficit.
Jing Yang, Zhuhao Wu, Nicolas Renier, David J Simon, Kunihiro Uryu, David S Park, Peter A Greer, Cathy Tournier, Roger J Davis, Marc Tessier-Lavigne. Cell 2015
Jing Yang, Zhuhao Wu, Nicolas Renier, David J Simon, Kunihiro Uryu, David S Park, Peter A Greer, Cathy Tournier, Roger J Davis, Marc Tessier-Lavigne. Cell 2015
25
Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration.
Selva Baltan, Denise M Inman, Camelia A Danilov, Richard S Morrison, David J Calkins, Philip J Horner. J Neurosci 2010
Selva Baltan, Denise M Inman, Camelia A Danilov, Richard S Morrison, David J Calkins, Philip J Horner. J Neurosci 2010
25
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma.
Gareth R Howell, Danilo G Macalinao, Gregory L Sousa, Michael Walden, Ileana Soto, Stephen C Kneeland, Jessica M Barbay, Benjamin L King, Jeffrey K Marchant, Matthew Hibbs,[...]. J Clin Invest 2011
Gareth R Howell, Danilo G Macalinao, Gregory L Sousa, Michael Walden, Ileana Soto, Stephen C Kneeland, Jessica M Barbay, Benjamin L King, Jeffrey K Marchant, Matthew Hibbs,[...]. J Clin Invest 2011
22
Metabolic Vulnerability in the Neurodegenerative Disease Glaucoma.
Denise M Inman, Mohammad Harun-Or-Rashid. Front Neurosci 2017
Denise M Inman, Mohammad Harun-Or-Rashid. Front Neurosci 2017
22
dSarm/Sarm1 is required for activation of an injury-induced axon death pathway.
Jeannette M Osterloh, Jing Yang, Timothy M Rooney, A Nicole Fox, Robert Adalbert, Eric H Powell, Amy E Sheehan, Michelle A Avery, Rachel Hackett, Mary A Logan,[...]. Science 2012
Jeannette M Osterloh, Jing Yang, Timothy M Rooney, A Nicole Fox, Robert Adalbert, Eric H Powell, Amy E Sheehan, Michelle A Avery, Rachel Hackett, Mary A Logan,[...]. Science 2012
22
Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial.
Flora Hui, Jessica Tang, Pete A Williams, Myra B McGuinness, Xavier Hadoux, Robert J Casson, Michael Coote, Ian A Trounce, Keith R Martin, Peter van Wijngaarden,[...]. Clin Exp Ophthalmol 2020
Flora Hui, Jessica Tang, Pete A Williams, Myra B McGuinness, Xavier Hadoux, Robert J Casson, Michael Coote, Ian A Trounce, Keith R Martin, Peter van Wijngaarden,[...]. Clin Exp Ophthalmol 2020
23
NAMPT-Mediated NAD(+) Biosynthesis Is Essential for Vision In Mice.
Jonathan B Lin, Shunsuke Kubota, Norimitsu Ban, Mitsukuni Yoshida, Andrea Santeford, Abdoulaye Sene, Rei Nakamura, Nicole Zapata, Miyuki Kubota, Kazuo Tsubota,[...]. Cell Rep 2016
Jonathan B Lin, Shunsuke Kubota, Norimitsu Ban, Mitsukuni Yoshida, Andrea Santeford, Abdoulaye Sene, Rei Nakamura, Nicole Zapata, Miyuki Kubota, Kazuo Tsubota,[...]. Cell Rep 2016
20
Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration.
Y Kitaoka, Y Munemasa, K Kojima, A Hirano, S Ueno, H Takagi. Cell Death Dis 2013
Y Kitaoka, Y Munemasa, K Kojima, A Hirano, S Ueno, H Takagi. Cell Death Dis 2013
20
A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration.
M Di Stefano, I Nascimento-Ferreira, G Orsomando, V Mori, J Gilley, R Brown, L Janeckova, M E Vargas, L A Worrell, A Loreto,[...]. Cell Death Differ 2015
M Di Stefano, I Nascimento-Ferreira, G Orsomando, V Mori, J Gilley, R Brown, L Janeckova, M E Vargas, L A Worrell, A Loreto,[...]. Cell Death Differ 2015
20
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms.
Felicitas Berger, Corinna Lau, Mathias Dahlmann, Mathias Ziegler. J Biol Chem 2005
Felicitas Berger, Corinna Lau, Mathias Dahlmann, Mathias Ziegler. J Biol Chem 2005
20
NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.
Yo Sasaki, Takashi Nakagawa, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt. Elife 2016
Yo Sasaki, Takashi Nakagawa, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt. Elife 2016
20
Wallerian degeneration, wld(s), and nmnat.
Michael P Coleman, Marc R Freeman. Annu Rev Neurosci 2010
Michael P Coleman, Marc R Freeman. Annu Rev Neurosci 2010
18
The number of people with glaucoma worldwide in 2010 and 2020.
H A Quigley, A T Broman. Br J Ophthalmol 2006
H A Quigley, A T Broman. Br J Ophthalmol 2006
18
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.
Samuel A J Trammell, Mark S Schmidt, Benjamin J Weidemann, Philip Redpath, Frank Jaksch, Ryan W Dellinger, Zhonggang Li, E Dale Abel, Marie E Migaud, Charles Brenner. Nat Commun 2016
Samuel A J Trammell, Mark S Schmidt, Benjamin J Weidemann, Philip Redpath, Frank Jaksch, Ryan W Dellinger, Zhonggang Li, E Dale Abel, Marie E Migaud, Charles Brenner. Nat Commun 2016
18
Safety of high-dose nicotinamide: a review.
M Knip, I F Douek, W P Moore, H A Gillmor, A E McLean, P J Bingley, E A Gale. Diabetologia 2000
M Knip, I F Douek, W P Moore, H A Gillmor, A E McLean, P J Bingley, E A Gale. Diabetologia 2000
18
NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.
Hongbo Zhang, Dongryeol Ryu, Yibo Wu, Karim Gariani, Xu Wang, Peiling Luan, Davide D'Amico, Eduardo R Ropelle, Matthias P Lutolf, Ruedi Aebersold,[...]. Science 2016
Hongbo Zhang, Dongryeol Ryu, Yibo Wu, Karim Gariani, Xu Wang, Peiling Luan, Davide D'Amico, Eduardo R Ropelle, Matthias P Lutolf, Ruedi Aebersold,[...]. Science 2016
18
Glaucoma: thinking in new ways-a rôle for autonomous axonal self-destruction and other compartmentalised processes?
Alan V Whitmore, Richard T Libby, Simon W M John. Prog Retin Eye Res 2005
Alan V Whitmore, Richard T Libby, Simon W M John. Prog Retin Eye Res 2005
18
Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences.
Gülgün Tezel. Prog Retin Eye Res 2006
Gülgün Tezel. Prog Retin Eye Res 2006
18
Rescue of peripheral and CNS axon defects in mice lacking NMNAT2.
Jonathan Gilley, Robert Adalbert, Gang Yu, Michael P Coleman. J Neurosci 2013
Jonathan Gilley, Robert Adalbert, Gang Yu, Michael P Coleman. J Neurosci 2013
18
Early microglia activation in a mouse model of chronic glaucoma.
Alejandra Bosco, Michael R Steele, Monica L Vetter. J Comp Neurol 2011
Alejandra Bosco, Michael R Steele, Monica L Vetter. J Comp Neurol 2011
18
Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma.
Gareth R Howell, Ileana Soto, Xianjun Zhu, Margaret Ryan, Danilo G Macalinao, Gregory L Sousa, Lura B Caddle, Katharine H MacNicoll, Jessica M Barbay, Vittorio Porciatti,[...]. J Clin Invest 2012
Gareth R Howell, Ileana Soto, Xianjun Zhu, Margaret Ryan, Danilo G Macalinao, Gregory L Sousa, Lura B Caddle, Katharine H MacNicoll, Jessica M Barbay, Vittorio Porciatti,[...]. J Clin Invest 2012
18
Neuroinflammation in glaucoma: A new opportunity.
Pete A Williams, Nick Marsh-Armstrong, Gareth R Howell. Exp Eye Res 2017
Pete A Williams, Nick Marsh-Armstrong, Gareth R Howell. Exp Eye Res 2017
18
Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation.
Jorge L Cueva Vargas, Ingrid K Osswald, Nicolas Unsain, Mark R Aurousseau, Philip A Barker, Derek Bowie, Adriana Di Polo. J Neurosci 2015
Jorge L Cueva Vargas, Ingrid K Osswald, Nicolas Unsain, Mark R Aurousseau, Philip A Barker, Derek Bowie, Adriana Di Polo. J Neurosci 2015
18
Intrinsic axonal degeneration pathways are critical for glaucomatous damage.
Gareth R Howell, Ileana Soto, Richard T Libby, Simon W M John. Exp Neurol 2013
Gareth R Howell, Ileana Soto, Richard T Libby, Simon W M John. Exp Neurol 2013
18
Distal axonopathy with structural persistence in glaucomatous neurodegeneration.
Samuel D Crish, Rebecca M Sappington, Denise M Inman, Philip J Horner, David J Calkins. Proc Natl Acad Sci U S A 2010
Samuel D Crish, Rebecca M Sappington, Denise M Inman, Philip J Horner, David J Calkins. Proc Natl Acad Sci U S A 2010
18
Investigations into Hypoxia and Oxidative Stress at the Optic Nerve Head in a Rat Model of Glaucoma.
Glyn Chidlow, John P M Wood, Robert J Casson. Front Neurosci 2017
Glyn Chidlow, John P M Wood, Robert J Casson. Front Neurosci 2017
18
Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma.
Gareth R Howell, Katharine H MacNicoll, Catherine E Braine, Ileana Soto, Danilo G Macalinao, Gregory L Sousa, Simon W M John. Neurobiol Dis 2014
Gareth R Howell, Katharine H MacNicoll, Catherine E Braine, Ileana Soto, Danilo G Macalinao, Gregory L Sousa, Simon W M John. Neurobiol Dis 2014
15
Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy.
Robert W Nickells, Gareth R Howell, Ileana Soto, Simon W M John. Annu Rev Neurosci 2012
Robert W Nickells, Gareth R Howell, Ileana Soto, Simon W M John. Annu Rev Neurosci 2012
15
NAD+ and sirtuins in aging and disease.
Shin-ichiro Imai, Leonard Guarente. Trends Cell Biol 2014
Shin-ichiro Imai, Leonard Guarente. Trends Cell Biol 2014
15
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