A citation-based method for searching scientific literature

Jang-Hyun Oh, Ju-Yeon Hyun, Alexander Varshavsky. Proc Natl Acad Sci U S A 2017
Times Cited: 34







List of co-cited articles
379 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


N-terminal acetylation of cellular proteins creates specific degradation signals.
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
445
64

Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway.
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
201
64


First Things First: Vital Protein Marks by N-Terminal Acetyltransferases.
Henriette Aksnes, Adrian Drazic, Michaël Marie, Thomas Arnesen. Trends Biochem Sci 2016
146
47

The N-end rule pathway and regulation by proteolysis.
Alexander Varshavsky. Protein Sci 2011
456
44

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes.
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
114
44

The N-terminal methionine of cellular proteins as a degradation signal.
Heon-Ki Kim, Ryu-Ryun Kim, Jang-Hyun Oh, Hanna Cho, Alexander Varshavsky, Cheol-Sang Hwang. Cell 2014
121
41

The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Daniel Finley, Helle D Ulrich, Thomas Sommer, Peter Kaiser. Genetics 2012
267
41

The N-end rule pathway.
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
254
38

The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators.
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T Takahashi, Alexander Varshavsky. Nature 2005
226
35

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments.
Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Proc Natl Acad Sci U S A 2012
102
35

Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
79
35

Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases.
Woo Suk Choi, Byung-Cheon Jeong, Yoo Jin Joo, Myeong-Ryeol Lee, Joon Kim, Michael J Eck, Hyun Kyu Song. Nat Struct Mol Biol 2010
101
32

The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions.
Daniel J Gibbs, Jaume Bacardit, Andreas Bachmair, Michael J Holdsworth. Trends Cell Biol 2014
134
32


The degradation signal in a short-lived protein.
A Bachmair, A Varshavsky. Cell 1989
359
32

N-degron and C-degron pathways of protein degradation.
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
222
32

Ubiquitin Ligases: Structure, Function, and Regulation.
Ning Zheng, Nitzan Shabek. Annu Rev Biochem 2017
581
29

Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Min Kyung Kim, Sun Joo Oh, Byung-Gil Lee, Hyun Kyu Song. Proc Natl Acad Sci U S A 2016
21
47

Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases.
Vinayak Vittal, Mikaela D Stewart, Peter S Brzovic, Rachel E Klevit. J Biol Chem 2015
57
29

Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway.
Konstantin I Piatkov, Jang-Hyun Oh, Yuan Liu, Alexander Varshavsky. Proc Natl Acad Sci U S A 2014
61
26

Structural basis of substrate recognition and specificity in the N-end rule pathway.
Edna Matta-Camacho, Guennadi Kozlov, Flora F Li, Kalle Gehring. Nat Struct Mol Biol 2010
75
26

The N-end rule pathway: from recognition by N-recognins, to destruction by AAA+proteases.
D A Dougan, D Micevski, K N Truscott. Biochim Biophys Acta 2012
85
26

N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Daniel C Scott, Julie K Monda, Eric J Bennett, J Wade Harper, Brenda A Schulman. Science 2011
197
26


N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Petra Van Damme, Marta Lasa, Bogdan Polevoda, Cristina Gazquez, Alberto Elosegui-Artola, Duk Soo Kim, Elena De Juan-Pardo, Kimberly Demeyer, Kristine Hole, Esther Larrea,[...]. Proc Natl Acad Sci U S A 2012
129
26

The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases.
Cheol-Sang Hwang, Anna Shemorry, Daniel Auerbach, Alexander Varshavsky. Nat Cell Biol 2010
102
26

In vivo aspects of protein folding and quality control.
David Balchin, Manajit Hayer-Hartl, F Ulrich Hartl. Science 2016
722
26


Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway.
Jeong-Mok Kim, Ok-Hee Seok, Shinyeong Ju, Ji-Eun Heo, Jeonghun Yeom, Da-Som Kim, Joo-Yeon Yoo, Alexander Varshavsky, Cheolju Lee, Cheol-Sang Hwang. Science 2018
48
26

Basic Medical Research Award. The ubiquitin system.
A Hershko, A Ciechanover, A Varshavsky. Nat Med 2000
538
26

Structure and Function of the 26S Proteasome.
Jared A M Bard, Ellen A Goodall, Eric R Greene, Erik Jonsson, Ken C Dong, Andreas Martin. Annu Rev Biochem 2018
311
26

Understanding the Pro/N-end rule pathway.
David A Dougan, Alexander Varshavsky. Nat Chem Biol 2018
14
64

Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays.
Brandon Wadas, Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. J Biol Chem 2016
20
40

The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.
Konstantin I Piatkov, Luca Colnaghi, Miklos Békés, Alexander Varshavsky, Tony T Huang. Mol Cell 2012
51
23

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans.
Thomas Arnesen, Petra Van Damme, Bogdan Polevoda, Kenny Helsens, Rune Evjenth, Niklaas Colaert, Jan Erik Varhaug, Joël Vandekerckhove, Johan R Lillehaug, Fred Sherman,[...]. Proc Natl Acad Sci U S A 2009
373
23


Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Cheng Dong, Heng Zhang, Li Li, Wolfram Tempel, Peter Loppnau, Jinrong Min. Nat Chem Biol 2018
51
23

Proteasome Structure and Assembly.
Lauren Budenholzer, Chin Leng Cheng, Yanjie Li, Mark Hochstrasser. J Mol Biol 2017
176
23

Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway.
Sang-Eun Park, Jeong-Mok Kim, Ok-Hee Seok, Hanna Cho, Brandon Wadas, Seon-Young Kim, Alexander Varshavsky, Cheol-Sang Hwang. Science 2015
96
20

A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes.
Carsten Janke, Maria M Magiera, Nicole Rathfelder, Christof Taxis, Simone Reber, Hiromi Maekawa, Alexandra Moreno-Borchart, Georg Doenges, Etienne Schwob, Elmar Schiebel,[...]. Yeast 2004
20

An essential role of N-terminal arginylation in cardiovascular development.
Yong Tae Kwon, Anna S Kashina, Ilia V Davydov, Rong-Gui Hu, Jee Young An, Jai Wha Seo, Fangyong Du, Alexander Varshavsky. Science 2002
248
20


Remodeling of a delivery complex allows ClpS-mediated degradation of N-degron substrates.
Izarys Rivera-Rivera, Giselle Román-Hernández, Robert T Sauer, Tania A Baker. Proc Natl Acad Sci U S A 2014
33
21

The Logic of the 26S Proteasome.
Galen Andrew Collins, Alfred L Goldberg. Cell 2017
432
20

Defining the geometry of the two-component proteasome degron.
Tomonao Inobe, Susan Fishbain, Sumit Prakash, Andreas Matouschek. Nat Chem Biol 2011
123
20

N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
Young Dong Yoo, Su Ran Mun, Chang Hoon Ji, Ki Woon Sung, Keum Young Kang, Ah Jung Heo, Su Hyun Lee, Jee Young An, Joonsung Hwang, Xiang-Qun Xie,[...]. Proc Natl Acad Sci U S A 2018
33
21


Functional Roles of the E3 Ubiquitin Ligase UBR5 in Cancer.
Robert F Shearer, Mary Iconomou, Colin K W Watts, Darren N Saunders. Mol Cancer Res 2015
68
20

Structure of the human 26S proteasome at a resolution of 3.9 Å.
Andreas Schweitzer, Antje Aufderheide, Till Rudack, Florian Beck, Günter Pfeifer, Jürgen M Plitzko, Eri Sakata, Klaus Schulten, Friedrich Förster, Wolfgang Baumeister. Proc Natl Acad Sci U S A 2016
140
20


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.