Jang-Hyun Oh, Ju-Yeon Hyun, Alexander Varshavsky. Proc Natl Acad Sci U S A 2017
Times Cited: 34
Times Cited: 34
Times Cited
Times Co-cited
Similarity
N-terminal acetylation of cellular proteins creates specific degradation signals.
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
64
Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway.
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
64
In vivo half-life of a protein is a function of its amino-terminal residue.
A Bachmair, D Finley, A Varshavsky. Science 1986
A Bachmair, D Finley, A Varshavsky. Science 1986
52
First Things First: Vital Protein Marks by N-Terminal Acetyltransferases.
Henriette Aksnes, Adrian Drazic, Michaël Marie, Thomas Arnesen. Trends Biochem Sci 2016
Henriette Aksnes, Adrian Drazic, Michaël Marie, Thomas Arnesen. Trends Biochem Sci 2016
47
44
An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes.
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
44
The N-terminal methionine of cellular proteins as a degradation signal.
Heon-Ki Kim, Ryu-Ryun Kim, Jang-Hyun Oh, Hanna Cho, Alexander Varshavsky, Cheol-Sang Hwang. Cell 2014
Heon-Ki Kim, Ryu-Ryun Kim, Jang-Hyun Oh, Hanna Cho, Alexander Varshavsky, Cheol-Sang Hwang. Cell 2014
41
The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Daniel Finley, Helle D Ulrich, Thomas Sommer, Peter Kaiser. Genetics 2012
Daniel Finley, Helle D Ulrich, Thomas Sommer, Peter Kaiser. Genetics 2012
41
The N-end rule pathway.
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
38
The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators.
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T Takahashi, Alexander Varshavsky. Nature 2005
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T Takahashi, Alexander Varshavsky. Nature 2005
35
The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments.
Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Proc Natl Acad Sci U S A 2012
Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Proc Natl Acad Sci U S A 2012
35
Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
35
Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases.
Woo Suk Choi, Byung-Cheon Jeong, Yoo Jin Joo, Myeong-Ryeol Lee, Joon Kim, Michael J Eck, Hyun Kyu Song. Nat Struct Mol Biol 2010
Woo Suk Choi, Byung-Cheon Jeong, Yoo Jin Joo, Myeong-Ryeol Lee, Joon Kim, Michael J Eck, Hyun Kyu Song. Nat Struct Mol Biol 2010
32
The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions.
Daniel J Gibbs, Jaume Bacardit, Andreas Bachmair, Michael J Holdsworth. Trends Cell Biol 2014
Daniel J Gibbs, Jaume Bacardit, Andreas Bachmair, Michael J Holdsworth. Trends Cell Biol 2014
32
Life and death of proteins after protease cleavage: protein degradation by the N-end rule pathway.
Nico Dissmeyer, Susana Rivas, Emmanuelle Graciet. New Phytol 2018
Nico Dissmeyer, Susana Rivas, Emmanuelle Graciet. New Phytol 2018
32
N-degron and C-degron pathways of protein degradation.
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
32
Ubiquitin Ligases: Structure, Function, and Regulation.
Ning Zheng, Nitzan Shabek. Annu Rev Biochem 2017
Ning Zheng, Nitzan Shabek. Annu Rev Biochem 2017
29
Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.
Min Kyung Kim, Sun Joo Oh, Byung-Gil Lee, Hyun Kyu Song. Proc Natl Acad Sci U S A 2016
Min Kyung Kim, Sun Joo Oh, Byung-Gil Lee, Hyun Kyu Song. Proc Natl Acad Sci U S A 2016
47
Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases.
Vinayak Vittal, Mikaela D Stewart, Peter S Brzovic, Rachel E Klevit. J Biol Chem 2015
Vinayak Vittal, Mikaela D Stewart, Peter S Brzovic, Rachel E Klevit. J Biol Chem 2015
29
Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway.
Konstantin I Piatkov, Jang-Hyun Oh, Yuan Liu, Alexander Varshavsky. Proc Natl Acad Sci U S A 2014
Konstantin I Piatkov, Jang-Hyun Oh, Yuan Liu, Alexander Varshavsky. Proc Natl Acad Sci U S A 2014
26
Structural basis of substrate recognition and specificity in the N-end rule pathway.
Edna Matta-Camacho, Guennadi Kozlov, Flora F Li, Kalle Gehring. Nat Struct Mol Biol 2010
Edna Matta-Camacho, Guennadi Kozlov, Flora F Li, Kalle Gehring. Nat Struct Mol Biol 2010
26
The N-end rule pathway: from recognition by N-recognins, to destruction by AAA+proteases.
D A Dougan, D Micevski, K N Truscott. Biochim Biophys Acta 2012
D A Dougan, D Micevski, K N Truscott. Biochim Biophys Acta 2012
26
N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.
Daniel C Scott, Julie K Monda, Eric J Bennett, J Wade Harper, Brenda A Schulman. Science 2011
Daniel C Scott, Julie K Monda, Eric J Bennett, J Wade Harper, Brenda A Schulman. Science 2011
26
Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability.
H Rao, F Uhlmann, K Nasmyth, A Varshavsky. Nature 2001
H Rao, F Uhlmann, K Nasmyth, A Varshavsky. Nature 2001
26
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Petra Van Damme, Marta Lasa, Bogdan Polevoda, Cristina Gazquez, Alberto Elosegui-Artola, Duk Soo Kim, Elena De Juan-Pardo, Kimberly Demeyer, Kristine Hole, Esther Larrea,[...]. Proc Natl Acad Sci U S A 2012
Petra Van Damme, Marta Lasa, Bogdan Polevoda, Cristina Gazquez, Alberto Elosegui-Artola, Duk Soo Kim, Elena De Juan-Pardo, Kimberly Demeyer, Kristine Hole, Esther Larrea,[...]. Proc Natl Acad Sci U S A 2012
26
The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases.
Cheol-Sang Hwang, Anna Shemorry, Daniel Auerbach, Alexander Varshavsky. Nat Cell Biol 2010
Cheol-Sang Hwang, Anna Shemorry, Daniel Auerbach, Alexander Varshavsky. Nat Cell Biol 2010
26
In vivo aspects of protein folding and quality control.
David Balchin, Manajit Hayer-Hartl, F Ulrich Hartl. Science 2016
David Balchin, Manajit Hayer-Hartl, F Ulrich Hartl. Science 2016
26
'Spalog' and 'sequelog': neutral terms for spatial and sequence similarity.
Alexander Varshavsky. Curr Biol 2004
Alexander Varshavsky. Curr Biol 2004
26
Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway.
Jeong-Mok Kim, Ok-Hee Seok, Shinyeong Ju, Ji-Eun Heo, Jeonghun Yeom, Da-Som Kim, Joo-Yeon Yoo, Alexander Varshavsky, Cheolju Lee, Cheol-Sang Hwang. Science 2018
Jeong-Mok Kim, Ok-Hee Seok, Shinyeong Ju, Ji-Eun Heo, Jeonghun Yeom, Da-Som Kim, Joo-Yeon Yoo, Alexander Varshavsky, Cheolju Lee, Cheol-Sang Hwang. Science 2018
26
Basic Medical Research Award. The ubiquitin system.
A Hershko, A Ciechanover, A Varshavsky. Nat Med 2000
A Hershko, A Ciechanover, A Varshavsky. Nat Med 2000
26
Structure and Function of the 26S Proteasome.
Jared A M Bard, Ellen A Goodall, Eric R Greene, Erik Jonsson, Ken C Dong, Andreas Martin. Annu Rev Biochem 2018
Jared A M Bard, Ellen A Goodall, Eric R Greene, Erik Jonsson, Ken C Dong, Andreas Martin. Annu Rev Biochem 2018
26
64
Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays.
Brandon Wadas, Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. J Biol Chem 2016
Brandon Wadas, Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. J Biol Chem 2016
40
The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.
Konstantin I Piatkov, Luca Colnaghi, Miklos Békés, Alexander Varshavsky, Tony T Huang. Mol Cell 2012
Konstantin I Piatkov, Luca Colnaghi, Miklos Békés, Alexander Varshavsky, Tony T Huang. Mol Cell 2012
23
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans.
Thomas Arnesen, Petra Van Damme, Bogdan Polevoda, Kenny Helsens, Rune Evjenth, Niklaas Colaert, Jan Erik Varhaug, Joël Vandekerckhove, Johan R Lillehaug, Fred Sherman,[...]. Proc Natl Acad Sci U S A 2009
Thomas Arnesen, Petra Van Damme, Bogdan Polevoda, Kenny Helsens, Rune Evjenth, Niklaas Colaert, Jan Erik Varhaug, Joël Vandekerckhove, Johan R Lillehaug, Fred Sherman,[...]. Proc Natl Acad Sci U S A 2009
23
Crosstalk and Interplay between the Ubiquitin-Proteasome System and Autophagy.
Chang Hoon Ji, Yong Tae Kwon. Mol Cells 2017
Chang Hoon Ji, Yong Tae Kwon. Mol Cells 2017
23
Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Cheng Dong, Heng Zhang, Li Li, Wolfram Tempel, Peter Loppnau, Jinrong Min. Nat Chem Biol 2018
Cheng Dong, Heng Zhang, Li Li, Wolfram Tempel, Peter Loppnau, Jinrong Min. Nat Chem Biol 2018
23
Proteasome Structure and Assembly.
Lauren Budenholzer, Chin Leng Cheng, Yanjie Li, Mark Hochstrasser. J Mol Biol 2017
Lauren Budenholzer, Chin Leng Cheng, Yanjie Li, Mark Hochstrasser. J Mol Biol 2017
23
Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway.
Sang-Eun Park, Jeong-Mok Kim, Ok-Hee Seok, Hanna Cho, Brandon Wadas, Seon-Young Kim, Alexander Varshavsky, Cheol-Sang Hwang. Science 2015
Sang-Eun Park, Jeong-Mok Kim, Ok-Hee Seok, Hanna Cho, Brandon Wadas, Seon-Young Kim, Alexander Varshavsky, Cheol-Sang Hwang. Science 2015
20
A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes.
Carsten Janke, Maria M Magiera, Nicole Rathfelder, Christof Taxis, Simone Reber, Hiromi Maekawa, Alexandra Moreno-Borchart, Georg Doenges, Etienne Schwob, Elmar Schiebel,[...]. Yeast 2004
Carsten Janke, Maria M Magiera, Nicole Rathfelder, Christof Taxis, Simone Reber, Hiromi Maekawa, Alexandra Moreno-Borchart, Georg Doenges, Etienne Schwob, Elmar Schiebel,[...]. Yeast 2004
20
An essential role of N-terminal arginylation in cardiovascular development.
Yong Tae Kwon, Anna S Kashina, Ilia V Davydov, Rong-Gui Hu, Jee Young An, Jai Wha Seo, Fangyong Du, Alexander Varshavsky. Science 2002
Yong Tae Kwon, Anna S Kashina, Ilia V Davydov, Rong-Gui Hu, Jee Young An, Jai Wha Seo, Fangyong Du, Alexander Varshavsky. Science 2002
20
Yeast N-terminal amidase. A new enzyme and component of the N-end rule pathway.
R T Baker, A Varshavsky. J Biol Chem 1995
R T Baker, A Varshavsky. J Biol Chem 1995
20
Remodeling of a delivery complex allows ClpS-mediated degradation of N-degron substrates.
Izarys Rivera-Rivera, Giselle Román-Hernández, Robert T Sauer, Tania A Baker. Proc Natl Acad Sci U S A 2014
Izarys Rivera-Rivera, Giselle Román-Hernández, Robert T Sauer, Tania A Baker. Proc Natl Acad Sci U S A 2014
21
Defining the geometry of the two-component proteasome degron.
Tomonao Inobe, Susan Fishbain, Sumit Prakash, Andreas Matouschek. Nat Chem Biol 2011
Tomonao Inobe, Susan Fishbain, Sumit Prakash, Andreas Matouschek. Nat Chem Biol 2011
20
N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
Young Dong Yoo, Su Ran Mun, Chang Hoon Ji, Ki Woon Sung, Keum Young Kang, Ah Jung Heo, Su Hyun Lee, Jee Young An, Joonsung Hwang, Xiang-Qun Xie,[...]. Proc Natl Acad Sci U S A 2018
Young Dong Yoo, Su Ran Mun, Chang Hoon Ji, Ki Woon Sung, Keum Young Kang, Ah Jung Heo, Su Hyun Lee, Jee Young An, Joonsung Hwang, Xiang-Qun Xie,[...]. Proc Natl Acad Sci U S A 2018
21
Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway.
G C Turner, F Du, A Varshavsky. Nature 2000
G C Turner, F Du, A Varshavsky. Nature 2000
20
Functional Roles of the E3 Ubiquitin Ligase UBR5 in Cancer.
Robert F Shearer, Mary Iconomou, Colin K W Watts, Darren N Saunders. Mol Cancer Res 2015
Robert F Shearer, Mary Iconomou, Colin K W Watts, Darren N Saunders. Mol Cancer Res 2015
20
Structure of the human 26S proteasome at a resolution of 3.9 Å.
Andreas Schweitzer, Antje Aufderheide, Till Rudack, Florian Beck, Günter Pfeifer, Jürgen M Plitzko, Eri Sakata, Klaus Schulten, Friedrich Förster, Wolfgang Baumeister. Proc Natl Acad Sci U S A 2016
Andreas Schweitzer, Antje Aufderheide, Till Rudack, Florian Beck, Günter Pfeifer, Jürgen M Plitzko, Eri Sakata, Klaus Schulten, Friedrich Förster, Wolfgang Baumeister. Proc Natl Acad Sci U S A 2016
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.