Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
Times Cited: 717
Times Cited: 717
Times Cited
Times Co-cited
Similarity
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
24
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
16
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
15
The diverse roles of DNA methylation in mammalian development and disease.
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
14
The DNA methyltransferase family: a versatile toolkit for epigenetic regulation.
Frank Lyko. Nat Rev Genet 2018
Frank Lyko. Nat Rev Genet 2018
13
DNA methylation: roles in mammalian development.
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
12
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
12
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
M Okano, D W Bell, D A Haber, E Li. Cell 1999
M Okano, D W Bell, D A Haber, E Li. Cell 1999
11
DNA methylation and its basic function.
Lisa D Moore, Thuc Le, Guoping Fan. Neuropsychopharmacology 2013
Lisa D Moore, Thuc Le, Guoping Fan. Neuropsychopharmacology 2013
10
Role of TET enzymes in DNA methylation, development, and cancer.
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
10
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
9
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K Das, Teemu Kivioja, Kashyap Dave, Fan Zhong,[...]. Science 2017
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K Das, Teemu Kivioja, Kashyap Dave, Fan Zhong,[...]. Science 2017
9
Regulation of chromatin by histone modifications.
Andrew J Bannister, Tony Kouzarides. Cell Res 2011
Andrew J Bannister, Tony Kouzarides. Cell Res 2011
8
8
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription.
William A Pastor, L Aravind, Anjana Rao. Nat Rev Mol Cell Biol 2013
William A Pastor, L Aravind, Anjana Rao. Nat Rev Mol Cell Biol 2013
8
8
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
Wei Xu, Hui Yang, Ying Liu, Ying Yang, Ping Wang, Se-Hee Kim, Shinsuke Ito, Chen Yang, Pu Wang, Meng-Tao Xiao,[...]. Cancer Cell 2011
Wei Xu, Hui Yang, Ying Liu, Ying Yang, Ping Wang, Se-Hee Kim, Shinsuke Ito, Chen Yang, Pu Wang, Meng-Tao Xiao,[...]. Cancer Cell 2011
8
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors.
Mengtao Xiao, Hui Yang, Wei Xu, Shenghong Ma, Huaipeng Lin, Honguang Zhu, Lixia Liu, Ying Liu, Chen Yang, Yanhui Xu,[...]. Genes Dev 2012
Mengtao Xiao, Hui Yang, Wei Xu, Shenghong Ma, Huaipeng Lin, Honguang Zhu, Lixia Liu, Ying Liu, Chen Yang, Yanhui Xu,[...]. Genes Dev 2012
8
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
7
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.
Tian-Peng Gu, Fan Guo, Hui Yang, Hai-Ping Wu, Gui-Fang Xu, Wei Liu, Zhi-Guo Xie, Linyu Shi, Xinyi He, Seung-gi Jin,[...]. Nature 2011
Tian-Peng Gu, Fan Guo, Hui Yang, Hai-Ping Wu, Gui-Fang Xu, Wei Liu, Zhi-Guo Xie, Linyu Shi, Xinyi He, Seung-gi Jin,[...]. Nature 2011
7
5-Hydroxymethylcytosine is a predominantly stable DNA modification.
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
7
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Kelly Moran-Crusio, Linsey Reavie, Alan Shih, Omar Abdel-Wahab, Delphine Ndiaye-Lobry, Camille Lobry, Maria E Figueroa, Aparna Vasanthakumar, Jay Patel, Xinyang Zhao,[...]. Cancer Cell 2011
Kelly Moran-Crusio, Linsey Reavie, Alan Shih, Omar Abdel-Wahab, Delphine Ndiaye-Lobry, Camille Lobry, Maria E Figueroa, Aparna Vasanthakumar, Jay Patel, Xinyang Zhao,[...]. Cancer Cell 2011
7
7
Reversing DNA methylation: mechanisms, genomics, and biological functions.
Hao Wu, Yi Zhang. Cell 2014
Hao Wu, Yi Zhang. Cell 2014
7
UHRF1 plays a role in maintaining DNA methylation in mammalian cells.
Magnolia Bostick, Jong Kyong Kim, Pierre-Olivier Estève, Amander Clark, Sriharsa Pradhan, Steven E Jacobsen. Science 2007
Magnolia Bostick, Jong Kyong Kim, Pierre-Olivier Estève, Amander Clark, Sriharsa Pradhan, Steven E Jacobsen. Science 2007
6
Mutation in TET2 in myeloid cancers.
François Delhommeau, Sabrina Dupont, Véronique Della Valle, Chloé James, Severine Trannoy, Aline Massé, Olivier Kosmider, Jean-Pierre Le Couedic, Fabienne Robert, Antonio Alberdi,[...]. N Engl J Med 2009
François Delhommeau, Sabrina Dupont, Véronique Della Valle, Chloé James, Severine Trannoy, Aline Massé, Olivier Kosmider, Jean-Pierre Le Couedic, Fabienne Robert, Antonio Alberdi,[...]. N Engl J Med 2009
6
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Christine Guo Lian, Yufei Xu, Craig Ceol, Feizhen Wu, Allison Larson, Karen Dresser, Wenqi Xu, Li Tan, Yeguang Hu, Qian Zhan,[...]. Cell 2012
Christine Guo Lian, Yufei Xu, Craig Ceol, Feizhen Wu, Allison Larson, Karen Dresser, Wenqi Xu, Li Tan, Yeguang Hu, Qian Zhan,[...]. Cell 2012
6
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
Cyril Quivoron, Lucile Couronné, Véronique Della Valle, Cécile K Lopez, Isabelle Plo, Orianne Wagner-Ballon, Marcio Do Cruzeiro, Francois Delhommeau, Bertrand Arnulf, Marc-Henri Stern,[...]. Cancer Cell 2011
Cyril Quivoron, Lucile Couronné, Véronique Della Valle, Cécile K Lopez, Isabelle Plo, Orianne Wagner-Ballon, Marcio Do Cruzeiro, Francois Delhommeau, Bertrand Arnulf, Marc-Henri Stern,[...]. Cancer Cell 2011
6
Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6.
Qian Zhang, Kai Zhao, Qicong Shen, Yanmei Han, Yan Gu, Xia Li, Dezhi Zhao, Yiqi Liu, Chunmei Wang, Xiang Zhang,[...]. Nature 2015
Qian Zhang, Kai Zhao, Qicong Shen, Yanmei Han, Yan Gu, Xia Li, Dezhi Zhao, Yiqi Liu, Chunmei Wang, Xiang Zhang,[...]. Nature 2015
6
Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies.
Chan-Wang J Lio, Hiroshi Yuita, Anjana Rao. Blood 2019
Chan-Wang J Lio, Hiroshi Yuita, Anjana Rao. Blood 2019
9
Human DNA methylomes at base resolution show widespread epigenomic differences.
Ryan Lister, Mattia Pelizzola, Robert H Dowen, R David Hawkins, Gary Hon, Julian Tonti-Filippini, Joseph R Nery, Leonard Lee, Zhen Ye, Que-Minh Ngo,[...]. Nature 2009
Ryan Lister, Mattia Pelizzola, Robert H Dowen, R David Hawkins, Gary Hon, Julian Tonti-Filippini, Joseph R Nery, Leonard Lee, Zhen Ye, Que-Minh Ngo,[...]. Nature 2009
6
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals.
Rudolf Jaenisch, Adrian Bird. Nat Genet 2003
Rudolf Jaenisch, Adrian Bird. Nat Genet 2003
5
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.
Yujiang Shi, Fei Lan, Caitlin Matson, Peter Mulligan, Johnathan R Whetstine, Philip A Cole, Robert A Casero, Yang Shi. Cell 2004
Yujiang Shi, Fei Lan, Caitlin Matson, Peter Mulligan, Johnathan R Whetstine, Philip A Cole, Robert A Casero, Yang Shi. Cell 2004
5
Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role.
Krista S Crider, Thomas P Yang, Robert J Berry, Lynn B Bailey. Adv Nutr 2012
Krista S Crider, Thomas P Yang, Robert J Berry, Lynn B Bailey. Adv Nutr 2012
5
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
5
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.
Patrick S Ward, Jay Patel, David R Wise, Omar Abdel-Wahab, Bryson D Bennett, Hilary A Coller, Justin R Cross, Valeria R Fantin, Cyrus V Hedvat, Alexander E Perl,[...]. Cancer Cell 2010
Patrick S Ward, Jay Patel, David R Wise, Omar Abdel-Wahab, Bryson D Bennett, Hilary A Coller, Justin R Cross, Valeria R Fantin, Cyrus V Hedvat, Alexander E Perl,[...]. Cancer Cell 2010
5
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.
Lenny Dang, David W White, Stefan Gross, Bryson D Bennett, Mark A Bittinger, Edward M Driggers, Valeria R Fantin, Hyun Gyung Jang, Shengfang Jin, Marie C Keenan,[...]. Nature 2009
Lenny Dang, David W White, Stefan Gross, Bryson D Bennett, Mark A Bittinger, Edward M Driggers, Valeria R Fantin, Hyun Gyung Jang, Shengfang Jin, Marie C Keenan,[...]. Nature 2009
5
Dynamic DNA methylation: In the right place at the right time.
Chongyuan Luo, Petra Hajkova, Joseph R Ecker. Science 2018
Chongyuan Luo, Petra Hajkova, Joseph R Ecker. Science 2018
5
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
Alain R Weber, Claudia Krawczyk, Adam B Robertson, Anna Kuśnierczyk, Cathrine B Vågbø, David Schuermann, Arne Klungland, Primo Schär. Nat Commun 2016
Alain R Weber, Claudia Krawczyk, Adam B Robertson, Anna Kuśnierczyk, Cathrine B Vågbø, David Schuermann, Arne Klungland, Primo Schär. Nat Commun 2016
5
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Myunggon Ko, Yun Huang, Anna M Jankowska, Utz J Pape, Mamta Tahiliani, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Kian Peng Koh, Rebecca Ganetzky,[...]. Nature 2010
Myunggon Ko, Yun Huang, Anna M Jankowska, Utz J Pape, Mamta Tahiliani, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Kian Peng Koh, Rebecca Ganetzky,[...]. Nature 2010
5
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.
Omar Abdel-Wahab, Ann Mullally, Cyrus Hedvat, Guillermo Garcia-Manero, Jay Patel, Martha Wadleigh, Sebastien Malinge, JinJuan Yao, Outi Kilpivaara, Rukhmi Bhat,[...]. Blood 2009
Omar Abdel-Wahab, Ann Mullally, Cyrus Hedvat, Guillermo Garcia-Manero, Jay Patel, Martha Wadleigh, Sebastien Malinge, JinJuan Yao, Outi Kilpivaara, Rukhmi Bhat,[...]. Blood 2009
5
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies.
Zhe Li, Xiaoqiang Cai, Chen-Leng Cai, Jiapeng Wang, Wenyong Zhang, Bruce E Petersen, Feng-Chun Yang, Mingjiang Xu. Blood 2011
Zhe Li, Xiaoqiang Cai, Chen-Leng Cai, Jiapeng Wang, Wenyong Zhang, Bruce E Petersen, Feng-Chun Yang, Mingjiang Xu. Blood 2011
5
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice.
Myunggon Ko, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Elizabeth C Thompson, Ryan Hastie, Angeliki Tsangaratou, Klaus Rajewsky, Sergei B Koralov, Anjana Rao. Proc Natl Acad Sci U S A 2011
Myunggon Ko, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Elizabeth C Thompson, Ryan Hastie, Angeliki Tsangaratou, Klaus Rajewsky, Sergei B Koralov, Anjana Rao. Proc Natl Acad Sci U S A 2011
5
WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.
Yiping Wang, Mengtao Xiao, Xiufei Chen, Leilei Chen, Yanping Xu, Lei Lv, Pu Wang, Hui Yang, Shenghong Ma, Huaipeng Lin,[...]. Mol Cell 2015
Yiping Wang, Mengtao Xiao, Xiufei Chen, Leilei Chen, Yanping Xu, Lei Lv, Pu Wang, Hui Yang, Shenghong Ma, Huaipeng Lin,[...]. Mol Cell 2015
5
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.
Myunggon Ko, Jungeun An, Hozefa S Bandukwala, Lukas Chavez, Tarmo Aijö, William A Pastor, Matthew F Segal, Huiming Li, Kian Peng Koh, Harri Lähdesmäki,[...]. Nature 2013
Myunggon Ko, Jungeun An, Hozefa S Bandukwala, Lukas Chavez, Tarmo Aijö, William A Pastor, Matthew F Segal, Huiming Li, Kian Peng Koh, Harri Lähdesmäki,[...]. Nature 2013
5
Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.
Di Wu, Di Hu, Hao Chen, Guoming Shi, Irfete S Fetahu, Feizhen Wu, Kimberlie Rabidou, Rui Fang, Li Tan, Shuyun Xu,[...]. Nature 2018
Di Wu, Di Hu, Hao Chen, Guoming Shi, Irfete S Fetahu, Feizhen Wu, Kimberlie Rabidou, Rui Fang, Li Tan, Shuyun Xu,[...]. Nature 2018
5
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.