Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
Times Cited: 717
Times Cited: 717
Times Cited
Times Co-cited
Similarity
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
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The diverse roles of DNA methylation in mammalian development and disease.
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
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The DNA methyltransferase family: a versatile toolkit for epigenetic regulation.
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DNA methylation: roles in mammalian development.
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
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Lisa D Moore, Thuc Le, Guoping Fan. Neuropsychopharmacology 2013
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Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
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Impact of cytosine methylation on DNA binding specificities of human transcription factors.
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TETonic shift: biological roles of TET proteins in DNA demethylation and transcription.
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Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
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Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors.
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The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.
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5-Hydroxymethylcytosine is a predominantly stable DNA modification.
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
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Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
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Reversing DNA methylation: mechanisms, genomics, and biological functions.
Hao Wu, Yi Zhang. Cell 2014
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UHRF1 plays a role in maintaining DNA methylation in mammalian cells.
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Mutation in TET2 in myeloid cancers.
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6
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
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Christine Guo Lian, Yufei Xu, Craig Ceol, Feizhen Wu, Allison Larson, Karen Dresser, Wenqi Xu, Li Tan, Yeguang Hu, Qian Zhan,[...]. Cell 2012
6
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.
Cyril Quivoron, Lucile Couronné, Véronique Della Valle, Cécile K Lopez, Isabelle Plo, Orianne Wagner-Ballon, Marcio Do Cruzeiro, Francois Delhommeau, Bertrand Arnulf, Marc-Henri Stern,[...]. Cancer Cell 2011
Cyril Quivoron, Lucile Couronné, Véronique Della Valle, Cécile K Lopez, Isabelle Plo, Orianne Wagner-Ballon, Marcio Do Cruzeiro, Francois Delhommeau, Bertrand Arnulf, Marc-Henri Stern,[...]. Cancer Cell 2011
6
Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6.
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Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies.
Chan-Wang J Lio, Hiroshi Yuita, Anjana Rao. Blood 2019
Chan-Wang J Lio, Hiroshi Yuita, Anjana Rao. Blood 2019
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Human DNA methylomes at base resolution show widespread epigenomic differences.
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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals.
Rudolf Jaenisch, Adrian Bird. Nat Genet 2003
Rudolf Jaenisch, Adrian Bird. Nat Genet 2003
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Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.
Yujiang Shi, Fei Lan, Caitlin Matson, Peter Mulligan, Johnathan R Whetstine, Philip A Cole, Robert A Casero, Yang Shi. Cell 2004
Yujiang Shi, Fei Lan, Caitlin Matson, Peter Mulligan, Johnathan R Whetstine, Philip A Cole, Robert A Casero, Yang Shi. Cell 2004
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Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role.
Krista S Crider, Thomas P Yang, Robert J Berry, Lynn B Bailey. Adv Nutr 2012
Krista S Crider, Thomas P Yang, Robert J Berry, Lynn B Bailey. Adv Nutr 2012
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TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
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The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.
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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.
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Dynamic DNA methylation: In the right place at the right time.
Chongyuan Luo, Petra Hajkova, Joseph R Ecker. Science 2018
Chongyuan Luo, Petra Hajkova, Joseph R Ecker. Science 2018
5
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
Alain R Weber, Claudia Krawczyk, Adam B Robertson, Anna Kuśnierczyk, Cathrine B Vågbø, David Schuermann, Arne Klungland, Primo Schär. Nat Commun 2016
Alain R Weber, Claudia Krawczyk, Adam B Robertson, Anna Kuśnierczyk, Cathrine B Vågbø, David Schuermann, Arne Klungland, Primo Schär. Nat Commun 2016
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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Myunggon Ko, Yun Huang, Anna M Jankowska, Utz J Pape, Mamta Tahiliani, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Kian Peng Koh, Rebecca Ganetzky,[...]. Nature 2010
Myunggon Ko, Yun Huang, Anna M Jankowska, Utz J Pape, Mamta Tahiliani, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Kian Peng Koh, Rebecca Ganetzky,[...]. Nature 2010
5
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.
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5
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies.
Zhe Li, Xiaoqiang Cai, Chen-Leng Cai, Jiapeng Wang, Wenyong Zhang, Bruce E Petersen, Feng-Chun Yang, Mingjiang Xu. Blood 2011
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5
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice.
Myunggon Ko, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Elizabeth C Thompson, Ryan Hastie, Angeliki Tsangaratou, Klaus Rajewsky, Sergei B Koralov, Anjana Rao. Proc Natl Acad Sci U S A 2011
Myunggon Ko, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Elizabeth C Thompson, Ryan Hastie, Angeliki Tsangaratou, Klaus Rajewsky, Sergei B Koralov, Anjana Rao. Proc Natl Acad Sci U S A 2011
5
WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.
Yiping Wang, Mengtao Xiao, Xiufei Chen, Leilei Chen, Yanping Xu, Lei Lv, Pu Wang, Hui Yang, Shenghong Ma, Huaipeng Lin,[...]. Mol Cell 2015
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5
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.
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Myunggon Ko, Jungeun An, Hozefa S Bandukwala, Lukas Chavez, Tarmo Aijö, William A Pastor, Matthew F Segal, Huiming Li, Kian Peng Koh, Harri Lähdesmäki,[...]. Nature 2013
5
Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.
Di Wu, Di Hu, Hao Chen, Guoming Shi, Irfete S Fetahu, Feizhen Wu, Kimberlie Rabidou, Rui Fang, Li Tan, Shuyun Xu,[...]. Nature 2018
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5
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.