Sydney M Shaffer, Margaret C Dunagin, Stefan R Torborg, Eduardo A Torre, Benjamin Emert, Clemens Krepler, Marilda Beqiri, Katrin Sproesser, Patricia A Brafford, Min Xiao, Elliott Eggan, Ioannis N Anastopoulos, Cesar A Vargas-Garcia, Abhyudai Singh, Katherine L Nathanson, Meenhard Herlyn, Arjun Raj. Nature 2017
Times Cited: 477
Times Cited: 477
Times Cited
Times Co-cited
Similarity
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations.
Sreenath V Sharma, Diana Y Lee, Bihua Li, Margaret P Quinlan, Fumiyuki Takahashi, Shyamala Maheswaran, Ultan McDermott, Nancy Azizian, Lee Zou, Michael A Fischbach,[...]. Cell 2010
Sreenath V Sharma, Diana Y Lee, Bihua Li, Margaret P Quinlan, Fumiyuki Takahashi, Shyamala Maheswaran, Ultan McDermott, Nancy Azizian, Lee Zou, Michael A Fischbach,[...]. Cell 2010
35
Toward Minimal Residual Disease-Directed Therapy in Melanoma.
Florian Rambow, Aljosja Rogiers, Oskar Marin-Bejar, Sara Aibar, Julia Femel, Michael Dewaele, Panagiotis Karras, Daniel Brown, Young Hwan Chang, Maria Debiec-Rychter,[...]. Cell 2018
Florian Rambow, Aljosja Rogiers, Oskar Marin-Bejar, Sara Aibar, Julia Femel, Michael Dewaele, Panagiotis Karras, Daniel Brown, Young Hwan Chang, Maria Debiec-Rychter,[...]. Cell 2018
22
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
Itay Tirosh, Benjamin Izar, Sanjay M Prakadan, Marc H Wadsworth, Daniel Treacy, John J Trombetta, Asaf Rotem, Christopher Rodman, Christine Lian, George Murphy,[...]. Science 2016
Itay Tirosh, Benjamin Izar, Sanjay M Prakadan, Marc H Wadsworth, Daniel Treacy, John J Trombetta, Asaf Rotem, Christopher Rodman, Christine Lian, George Murphy,[...]. Science 2016
19
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.
Anoop P Patel, Itay Tirosh, John J Trombetta, Alex K Shalek, Shawn M Gillespie, Hiroaki Wakimoto, Daniel P Cahill, Brian V Nahed, William T Curry, Robert L Martuza,[...]. Science 2014
Anoop P Patel, Itay Tirosh, John J Trombetta, Alex K Shalek, Shawn M Gillespie, Hiroaki Wakimoto, Daniel P Cahill, Brian V Nahed, William T Curry, Robert L Martuza,[...]. Science 2014
14
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition.
Aaron N Hata, Matthew J Niederst, Hannah L Archibald, Maria Gomez-Caraballo, Faria M Siddiqui, Hillary E Mulvey, Yosef E Maruvka, Fei Ji, Hyo-eun C Bhang, Viveksagar Krishnamurthy Radhakrishna,[...]. Nat Med 2016
Aaron N Hata, Matthew J Niederst, Hannah L Archibald, Maria Gomez-Caraballo, Faria M Siddiqui, Hillary E Mulvey, Yosef E Maruvka, Fei Ji, Hyo-eun C Bhang, Viveksagar Krishnamurthy Radhakrishna,[...]. Nat Med 2016
13
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.
Brian B Liau, Cem Sievers, Laura K Donohue, Shawn M Gillespie, William A Flavahan, Tyler E Miller, Andrew S Venteicher, Christine H Hebert, Christopher D Carey, Scott J Rodig,[...]. Cell Stem Cell 2017
Brian B Liau, Cem Sievers, Laura K Donohue, Shawn M Gillespie, William A Flavahan, Tyler E Miller, Andrew S Venteicher, Christine H Hebert, Christopher D Carey, Scott J Rodig,[...]. Cell Stem Cell 2017
13
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.
Alexander Roesch, Mizuho Fukunaga-Kalabis, Elizabeth C Schmidt, Susan E Zabierowski, Patricia A Brafford, Adina Vultur, Devraj Basu, Phyllis Gimotty, Thomas Vogt, Meenhard Herlyn. Cell 2010
Alexander Roesch, Mizuho Fukunaga-Kalabis, Elizabeth C Schmidt, Susan E Zabierowski, Patricia A Brafford, Adina Vultur, Devraj Basu, Phyllis Gimotty, Thomas Vogt, Meenhard Herlyn. Cell 2010
13
Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells.
Piyush B Gupta, Christine M Fillmore, Guozhi Jiang, Sagi D Shapira, Kai Tao, Charlotte Kuperwasser, Eric S Lander. Cell 2011
Piyush B Gupta, Christine M Fillmore, Guozhi Jiang, Sagi D Shapira, Kai Tao, Charlotte Kuperwasser, Eric S Lander. Cell 2011
13
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.
Matthew J Hangauer, Vasanthi S Viswanathan, Matthew J Ryan, Dhruv Bole, John K Eaton, Alexandre Matov, Jacqueline Galeas, Harshil D Dhruv, Michael E Berens, Stuart L Schreiber,[...]. Nature 2017
Matthew J Hangauer, Vasanthi S Viswanathan, Matthew J Ryan, Dhruv Bole, John K Eaton, Alexandre Matov, Jacqueline Galeas, Harshil D Dhruv, Michael E Berens, Stuart L Schreiber,[...]. Nature 2017
13
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Yapeng Su, Wei Wei, Lidia Robert, Min Xue, Jennifer Tsoi, Angel Garcia-Diaz, Blanca Homet Moreno, Jungwoo Kim, Rachel H Ng, Jihoon W Lee,[...]. Proc Natl Acad Sci U S A 2017
Yapeng Su, Wei Wei, Lidia Robert, Min Xue, Jennifer Tsoi, Angel Garcia-Diaz, Blanca Homet Moreno, Jungwoo Kim, Rachel H Ng, Jihoon W Lee,[...]. Proc Natl Acad Sci U S A 2017
13
Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing.
Charissa Kim, Ruli Gao, Emi Sei, Rachel Brandt, Johan Hartman, Thomas Hatschek, Nicola Crosetto, Theodoros Foukakis, Nicholas E Navin. Cell 2018
Charissa Kim, Ruli Gao, Emi Sei, Rachel Brandt, Johan Hartman, Thomas Hatschek, Nicola Crosetto, Theodoros Foukakis, Nicholas E Navin. Cell 2018
12
Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells.
Michael Ramirez, Satwik Rajaram, Robert J Steininger, Daria Osipchuk, Maike A Roth, Leanna S Morinishi, Louise Evans, Weiyue Ji, Chien-Hsiang Hsu, Kevin Thurley,[...]. Nat Commun 2016
Michael Ramirez, Satwik Rajaram, Robert J Steininger, Daria Osipchuk, Maike A Roth, Leanna S Morinishi, Louise Evans, Weiyue Ji, Chien-Hsiang Hsu, Kevin Thurley,[...]. Nat Commun 2016
12
Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells.
Alexander Roesch, Adina Vultur, Ivan Bogeski, Huan Wang, Katharina M Zimmermann, David Speicher, Christina Körbel, Matthias W Laschke, Phyllis A Gimotty, Stephan E Philipp,[...]. Cancer Cell 2013
Alexander Roesch, Adina Vultur, Ivan Bogeski, Huan Wang, Katharina M Zimmermann, David Speicher, Christina Körbel, Matthias W Laschke, Phyllis A Gimotty, Stephan E Philipp,[...]. Cancer Cell 2013
11
11
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.
Sabrina L Spencer, Suzanne Gaudet, John G Albeck, John M Burke, Peter K Sorger. Nature 2009
Sabrina L Spencer, Suzanne Gaudet, John G Albeck, John M Burke, Peter K Sorger. Nature 2009
10
Epigenetic plasticity and the hallmarks of cancer.
William A Flavahan, Elizabeth Gaskell, Bradley E Bernstein. Science 2017
William A Flavahan, Elizabeth Gaskell, Bradley E Bernstein. Science 2017
10
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.
Judith Müller, Oscar Krijgsman, Jennifer Tsoi, Lidia Robert, Willy Hugo, Chunying Song, Xiangju Kong, Patricia A Possik, Paulien D M Cornelissen-Steijger, Marnix H Geukes Foppen,[...]. Nat Commun 2014
Judith Müller, Oscar Krijgsman, Jennifer Tsoi, Lidia Robert, Willy Hugo, Chunying Song, Xiangju Kong, Patricia A Possik, Paulien D M Cornelissen-Steijger, Marnix H Geukes Foppen,[...]. Nat Commun 2014
10
Non-Darwinian dynamics in therapy-induced cancer drug resistance.
Angela Oliveira Pisco, Amy Brock, Joseph Zhou, Andreas Moor, Mitra Mojtahedi, Dean Jackson, Sui Huang. Nat Commun 2013
Angela Oliveira Pisco, Amy Brock, Joseph Zhou, Andreas Moor, Mitra Mojtahedi, Dean Jackson, Sui Huang. Nat Commun 2013
10
Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.
Chong Sun, Liqin Wang, Sidong Huang, Guus J J E Heynen, Anirudh Prahallad, Caroline Robert, John Haanen, Christian Blank, Jelle Wesseling, Stefan M Willems,[...]. Nature 2014
Chong Sun, Liqin Wang, Sidong Huang, Guus J J E Heynen, Anirudh Prahallad, Caroline Robert, John Haanen, Christian Blank, Jelle Wesseling, Stefan M Willems,[...]. Nature 2014
10
Non-genetic cancer cell plasticity and therapy-induced stemness in tumour relapse: 'What does not kill me strengthens me'.
A O Pisco, S Huang. Br J Cancer 2015
A O Pisco, S Huang. Br J Cancer 2015
10
Non-genetic mechanisms of therapeutic resistance in cancer.
Jean-Christophe Marine, Sarah-Jane Dawson, Mark A Dawson. Nat Rev Cancer 2020
Jean-Christophe Marine, Sarah-Jane Dawson, Mark A Dawson. Nat Rev Cancer 2020
10
Non-genomic and Immune Evolution of Melanoma Acquiring MAPKi Resistance.
Willy Hugo, Hubing Shi, Lu Sun, Marco Piva, Chunying Song, Xiangju Kong, Gatien Moriceau, Aayoung Hong, Kimberly B Dahlman, Douglas B Johnson,[...]. Cell 2015
Willy Hugo, Hubing Shi, Lu Sun, Marco Piva, Chunying Song, Xiangju Kong, Gatien Moriceau, Aayoung Hong, Kimberly B Dahlman, Douglas B Johnson,[...]. Cell 2015
9
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.
David J Konieczkowski, Cory M Johannessen, Omar Abudayyeh, Jong Wook Kim, Zachary A Cooper, Adriano Piris, Dennie T Frederick, Michal Barzily-Rokni, Ravid Straussman, Rizwan Haq,[...]. Cancer Discov 2014
David J Konieczkowski, Cory M Johannessen, Omar Abudayyeh, Jong Wook Kim, Zachary A Cooper, Adriano Piris, Dennie T Frederick, Michal Barzily-Rokni, Ravid Straussman, Rizwan Haq,[...]. Cancer Discov 2014
9
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets.
Evan Z Macosko, Anindita Basu, Rahul Satija, James Nemesh, Karthik Shekhar, Melissa Goldman, Itay Tirosh, Allison R Bialas, Nolan Kamitaki, Emily M Martersteck,[...]. Cell 2015
Evan Z Macosko, Anindita Basu, Rahul Satija, James Nemesh, Karthik Shekhar, Melissa Goldman, Itay Tirosh, Allison R Bialas, Nolan Kamitaki, Emily M Martersteck,[...]. Cell 2015
9
Tumour heterogeneity and resistance to cancer therapies.
Ibiayi Dagogo-Jack, Alice T Shaw. Nat Rev Clin Oncol 2018
Ibiayi Dagogo-Jack, Alice T Shaw. Nat Rev Clin Oncol 2018
9
The great escape: tumour cell plasticity in resistance to targeted therapy.
Soufiane Boumahdi, Frederic J de Sauvage. Nat Rev Drug Discov 2020
Soufiane Boumahdi, Frederic J de Sauvage. Nat Rev Drug Discov 2020
9
The Genetic/Non-genetic Duality of Drug 'Resistance' in Cancer.
Ravi Salgia, Prakash Kulkarni. Trends Cancer 2018
Ravi Salgia, Prakash Kulkarni. Trends Cancer 2018
9
Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress.
Jennifer Tsoi, Lidia Robert, Kim Paraiso, Carlos Galvan, Katherine M Sheu, Johnson Lay, Deborah J L Wong, Mohammad Atefi, Roksana Shirazi, Xiaoyan Wang,[...]. Cancer Cell 2018
Jennifer Tsoi, Lidia Robert, Kim Paraiso, Carlos Galvan, Katherine M Sheu, Johnson Lay, Deborah J L Wong, Mohammad Atefi, Roksana Shirazi, Xiaoyan Wang,[...]. Cancer Cell 2018
9
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state.
Mohammad Fallahi-Sichani, Verena Becker, Benjamin Izar, Gregory J Baker, Jia-Ren Lin, Sarah A Boswell, Parin Shah, Asaf Rotem, Levi A Garraway, Peter K Sorger. Mol Syst Biol 2017
Mohammad Fallahi-Sichani, Verena Becker, Benjamin Izar, Gregory J Baker, Jia-Ren Lin, Sarah A Boswell, Parin Shah, Asaf Rotem, Levi A Garraway, Peter K Sorger. Mol Syst Biol 2017
9
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
9
Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy.
Hubing Shi, Willy Hugo, Xiangju Kong, Aayoung Hong, Richard C Koya, Gatien Moriceau, Thinle Chodon, Rongqing Guo, Douglas B Johnson, Kimberly B Dahlman,[...]. Cancer Discov 2014
Hubing Shi, Willy Hugo, Xiangju Kong, Aayoung Hong, Richard C Koya, Gatien Moriceau, Thinle Chodon, Rongqing Guo, Douglas B Johnson, Kimberly B Dahlman,[...]. Cancer Discov 2014
8
Nature, nurture, or chance: stochastic gene expression and its consequences.
Arjun Raj, Alexander van Oudenaarden. Cell 2008
Arjun Raj, Alexander van Oudenaarden. Cell 2008
8
Memory Sequencing Reveals Heritable Single-Cell Gene Expression Programs Associated with Distinct Cellular Behaviors.
Sydney M Shaffer, Benjamin L Emert, Raúl A Reyes Hueros, Christopher Cote, Guillaume Harmange, Dylan L Schaff, Ann E Sizemore, Rohit Gupte, Eduardo Torre, Abhyudai Singh,[...]. Cell 2020
Sydney M Shaffer, Benjamin L Emert, Raúl A Reyes Hueros, Christopher Cote, Guillaume Harmange, Dylan L Schaff, Ann E Sizemore, Rohit Gupte, Eduardo Torre, Abhyudai Singh,[...]. Cell 2020
17
Intratumor Heterogeneity: The Rosetta Stone of Therapy Resistance.
Andriy Marusyk, Michalina Janiszewska, Kornelia Polyak. Cancer Cell 2020
Andriy Marusyk, Michalina Janiszewska, Kornelia Polyak. Cancer Cell 2020
8
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
Hyo-eun C Bhang, David A Ruddy, Viveksagar Krishnamurthy Radhakrishna, Justina X Caushi, Rui Zhao, Matthew M Hims, Angad P Singh, Iris Kao, Daniel Rakiec, Pamela Shaw,[...]. Nat Med 2015
Hyo-eun C Bhang, David A Ruddy, Viveksagar Krishnamurthy Radhakrishna, Justina X Caushi, Rui Zhao, Matthew M Hims, Angad P Singh, Iris Kao, Daniel Rakiec, Pamela Shaw,[...]. Nat Med 2015
7
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution.
Nicholas McGranahan, Charles Swanton. Cancer Cell 2015
Nicholas McGranahan, Charles Swanton. Cancer Cell 2015
7
STAR: ultrafast universal RNA-seq aligner.
Alexander Dobin, Carrie A Davis, Felix Schlesinger, Jorg Drenkow, Chris Zaleski, Sonali Jha, Philippe Batut, Mark Chaisson, Thomas R Gingeras. Bioinformatics 2013
Alexander Dobin, Carrie A Davis, Felix Schlesinger, Jorg Drenkow, Chris Zaleski, Sonali Jha, Philippe Batut, Mark Chaisson, Thomas R Gingeras. Bioinformatics 2013
7
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
7
Simultaneous epitope and transcriptome measurement in single cells.
Marlon Stoeckius, Christoph Hafemeister, William Stephenson, Brian Houck-Loomis, Pratip K Chattopadhyay, Harold Swerdlow, Rahul Satija, Peter Smibert. Nat Methods 2017
Marlon Stoeckius, Christoph Hafemeister, William Stephenson, Brian Houck-Loomis, Pratip K Chattopadhyay, Harold Swerdlow, Rahul Satija, Peter Smibert. Nat Methods 2017
7
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.
Cyril Neftel, Julie Laffy, Mariella G Filbin, Toshiro Hara, Marni E Shore, Gilbert J Rahme, Alyssa R Richman, Dana Silverbush, McKenzie L Shaw, Christine M Hebert,[...]. Cell 2019
Cyril Neftel, Julie Laffy, Mariella G Filbin, Toshiro Hara, Marni E Shore, Gilbert J Rahme, Alyssa R Richman, Dana Silverbush, McKenzie L Shaw, Christine M Hebert,[...]. Cell 2019
7
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.
Marco Gerlinger, Andrew J Rowan, Stuart Horswell, M Math, James Larkin, David Endesfelder, Eva Gronroos, Pierre Martinez, Nicholas Matthews, Aengus Stewart,[...]. N Engl J Med 2012
Marco Gerlinger, Andrew J Rowan, Stuart Horswell, M Math, James Larkin, David Endesfelder, Eva Gronroos, Pierre Martinez, Nicholas Matthews, Aengus Stewart,[...]. N Engl J Med 2012
7
Tumour evolution inferred by single-cell sequencing.
Nicholas Navin, Jude Kendall, Jennifer Troge, Peter Andrews, Linda Rodgers, Jeanne McIndoo, Kerry Cook, Asya Stepansky, Dan Levy, Diane Esposito,[...]. Nature 2011
Nicholas Navin, Jude Kendall, Jennifer Troge, Peter Andrews, Linda Rodgers, Jeanne McIndoo, Kerry Cook, Asya Stepansky, Dan Levy, Diane Esposito,[...]. Nature 2011
7
Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction.
Gatien Moriceau, Willy Hugo, Aayoung Hong, Hubing Shi, Xiangju Kong, Clarissa C Yu, Richard C Koya, Ahmed A Samatar, Negar Khanlou, Jonathan Braun,[...]. Cancer Cell 2015
Gatien Moriceau, Willy Hugo, Aayoung Hong, Hubing Shi, Xiangju Kong, Clarissa C Yu, Richard C Koya, Ahmed A Samatar, Negar Khanlou, Jonathan Braun,[...]. Cancer Cell 2015
7
The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.
Eliezer M Van Allen, Nikhil Wagle, Antje Sucker, Daniel J Treacy, Cory M Johannessen, Eva M Goetz, Chelsea S Place, Amaro Taylor-Weiner, Steven Whittaker, Gregory V Kryukov,[...]. Cancer Discov 2014
Eliezer M Van Allen, Nikhil Wagle, Antje Sucker, Daniel J Treacy, Cory M Johannessen, Eva M Goetz, Chelsea S Place, Amaro Taylor-Weiner, Steven Whittaker, Gregory V Kryukov,[...]. Cancer Discov 2014
7
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
Ramin Nazarian, Hubing Shi, Qi Wang, Xiangju Kong, Richard C Koya, Hane Lee, Zugen Chen, Mi-Kyung Lee, Narsis Attar, Hooman Sazegar,[...]. Nature 2010
Ramin Nazarian, Hubing Shi, Qi Wang, Xiangju Kong, Richard C Koya, Hane Lee, Zugen Chen, Mi-Kyung Lee, Narsis Attar, Hooman Sazegar,[...]. Nature 2010
7
Cancer drug resistance: an evolving paradigm.
Caitriona Holohan, Sandra Van Schaeybroeck, Daniel B Longley, Patrick G Johnston. Nat Rev Cancer 2013
Caitriona Holohan, Sandra Van Schaeybroeck, Daniel B Longley, Patrick G Johnston. Nat Rev Cancer 2013
7
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future.
Nicholas McGranahan, Charles Swanton. Cell 2017
Nicholas McGranahan, Charles Swanton. Cell 2017
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.