A citation-based method for searching scientific literature

Douglas E Biancur, Joao A Paulo, Beata Małachowska, Maria Quiles Del Rey, Cristovão M Sousa, Xiaoxu Wang, Albert S W Sohn, Gerald C Chu, Steven P Gygi, J Wade Harper, Wojciech Fendler, Joseph D Mancias, Alec C Kimmelman. Nat Commun 2017
Times Cited: 121







List of co-cited articles
1391 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
52

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Shawn M Davidson, Thales Papagiannakopoulos, Benjamin A Olenchock, Julia E Heyman, Mark A Keibler, Alba Luengo, Matthew R Bauer, Abhishek K Jha, James P O'Brien, Kerry A Pierce,[...]. Cell Metab 2016
398
31

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
471
30

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition.
Alexander Muir, Laura V Danai, Dan Y Gui, Chiara Y Waingarten, Caroline A Lewis, Matthew G Vander Heiden. Elife 2017
129
26

From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
642
26

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
26

Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Matt I Gross, Susan D Demo, Jennifer B Dennison, Lijing Chen, Tania Chernov-Rogan, Bindu Goyal, Julie R Janes, Guy J Laidig, Evan R Lewis, Jim Li,[...]. Mol Cancer Ther 2014
484
25

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.
Jurre J Kamphorst, Michel Nofal, Cosimo Commisso, Sean R Hackett, Wenyun Lu, Elda Grabocka, Matthew G Vander Heiden, George Miller, Jeffrey A Drebin, Dafna Bar-Sagi,[...]. Cancer Res 2015
376
24

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Cosimo Commisso, Shawn M Davidson, Rengin G Soydaner-Azeloglu, Seth J Parker, Jurre J Kamphorst, Sean Hackett, Elda Grabocka, Michel Nofal, Jeffrey A Drebin, Craig B Thompson,[...]. Nature 2013
831
23

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
23

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Haoqiang Ying, Alec C Kimmelman, Costas A Lyssiotis, Sujun Hua, Gerald C Chu, Eliot Fletcher-Sananikone, Jason W Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L Coloff,[...]. Cell 2012
22

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.
Saverio Tardito, Anaïs Oudin, Shafiq U Ahmed, Fred Fack, Olivier Keunen, Liang Zheng, Hrvoje Miletic, Per Øystein Sakariassen, Adam Weinstock, Allon Wagner,[...]. Nat Cell Biol 2015
267
21

Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
783
20

The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.
Mariia O Yuneva, Teresa W M Fan, Thaddeus D Allen, Richard M Higashi, Dana V Ferraris, Takashi Tsukamoto, José M Matés, Francisco J Alonso, Chunmei Wang, Youngho Seo,[...]. Cell Metab 2012
398
20

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth.
Lifeng Yang, Abhinav Achreja, Tsz-Lun Yeung, Lingegowda S Mangala, Dahai Jiang, Cecil Han, Joelle Baddour, Juan C Marini, Joseph Ni, Ryuichi Nakahara,[...]. Cell Metab 2016
161
20

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Jared R Mayers, Margaret E Torrence, Laura V Danai, Thales Papagiannakopoulos, Shawn M Davidson, Matthew R Bauer, Allison N Lau, Brian W Ji, Purushottam D Dixit, Aaron M Hosios,[...]. Science 2016
268
19

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
18

Glutamine addiction: a new therapeutic target in cancer.
David R Wise, Craig B Thompson. Trends Biochem Sci 2010
981
18

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
18

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.
Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita, Takafumi Ochi, Karen I Zeller, Angelo M De Marzo, Jennifer E Van Eyk, Joshua T Mendell,[...]. Nature 2009
18

Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo,[...]. Nature 2017
483
18

Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability.
Mark R Sullivan, Laura V Danai, Caroline A Lewis, Sze Ham Chan, Dan Y Gui, Tenzin Kunchok, Emily A Dennstedt, Matthew G Vander Heiden, Alexander Muir. Elife 2019
128
17

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.
Rodrigo Romero, Volkan I Sayin, Shawn M Davidson, Matthew R Bauer, Simranjit X Singh, Sarah E LeBoeuf, Triantafyllia R Karakousi, Donald C Ellis, Arjun Bhutkar, Francisco J Sánchez-Rivera,[...]. Nat Med 2017
235
16

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.
Yan Xiang, Zachary E Stine, Jinsong Xia, Yunqi Lu, Roddy S O'Connor, Brian J Altman, Annie L Hsieh, Arvin M Gouw, Ajit G Thomas, Ping Gao,[...]. J Clin Invest 2015
219
16

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
15

Glutamine Metabolism in Cancer: Understanding the Heterogeneity.
Ahmad A Cluntun, Michael J Lukey, Richard A Cerione, Jason W Locasale. Trends Cancer 2017
191
15

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
David R Wise, Ralph J DeBerardinis, Anthony Mancuso, Nabil Sayed, Xiao-Yong Zhang, Harla K Pfeiffer, Ilana Nissim, Evgueni Daikhin, Marc Yudkoff, Steven B McMahon,[...]. Proc Natl Acad Sci U S A 2008
14

Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation.
Min Pan, Michael A Reid, Xazmin H Lowman, Rajan P Kulkarni, Thai Q Tran, Xiaojing Liu, Ying Yang, Jenny E Hernandez-Davies, Kimberly K Rosales, Haiqing Li,[...]. Nat Cell Biol 2016
149
14

Employing Metabolism to Improve the Diagnosis and Treatment of Pancreatic Cancer.
Christopher J Halbrook, Costas A Lyssiotis. Cancer Cell 2017
146
14

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Christian M Metallo, Paulo A Gameiro, Eric L Bell, Katherine R Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M Jewell, Zachary R Johnson, Darrell J Irvine, Leonard Guarente,[...]. Nature 2011
14

Glutamine and cancer: cell biology, physiology, and clinical opportunities.
Christopher T Hensley, Ajla T Wasti, Ralph J DeBerardinis. J Clin Invest 2013
622
13

Metabolic Heterogeneity in Human Lung Tumors.
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
509
13

Metabolic Interactions in the Tumor Microenvironment.
Costas A Lyssiotis, Alec C Kimmelman. Trends Cell Biol 2017
282
13

Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells.
Aaron M Hosios, Vivian C Hecht, Laura V Danai, Marc O Johnson, Jeffrey C Rathmell, Matthew L Steinhauser, Scott R Manalis, Matthew G Vander Heiden. Dev Cell 2016
267
13

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.
Volkan I Sayin, Sarah E LeBoeuf, Simranjit X Singh, Shawn M Davidson, Douglas Biancur, Betul S Guzelhan, Samantha W Alvarez, Warren L Wu, Triantafyllia R Karakousi, Anastasia Maria Zavitsanou,[...]. Elife 2017
89
14

Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target.
Luika A Timmerman, Thomas Holton, Mariia Yuneva, Raymond J Louie, Mercè Padró, Anneleen Daemen, Min Hu, Denise A Chan, Stephen P Ethier, Laura J van 't Veer,[...]. Cancer Cell 2013
291
13

Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.
Orianne Olivares, Jared R Mayers, Victoire Gouirand, Margaret E Torrence, Tristan Gicquel, Laurence Borge, Sophie Lac, Julie Roques, Marie-Noëlle Lavaut, Patrice Berthezène,[...]. Nat Commun 2017
131
13

Lactate Metabolism in Human Lung Tumors.
Brandon Faubert, Kevin Y Li, Ling Cai, Christopher T Hensley, Jiyeon Kim, Lauren G Zacharias, Chendong Yang, Quyen N Do, Sarah Doucette, Daniel Burguete,[...]. Cell 2017
455
13

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.
Jason R Cantor, Monther Abu-Remaileh, Naama Kanarek, Elizaveta Freinkman, Xin Gao, Abner Louissaint, Caroline A Lewis, David M Sabatini. Cell 2017
160
12

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
929
12

Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone.
Gaurab Chakrabarti, Zachary R Moore, Xiuquan Luo, Mariya Ilcheva, Aktar Ali, Mahesh Padanad, Yunyun Zhou, Yang Xie, Sandeep Burma, Pier P Scaglioni,[...]. Cancer Metab 2015
71
16

Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.
Isaac Marin-Valencia, Chendong Yang, Tomoyuki Mashimo, Steve Cho, Hyeonman Baek, Xiao-Li Yang, Kartik N Rajagopalan, Melissa Maddie, Vamsidhara Vemireddy, Zhenze Zhao,[...]. Cell Metab 2012
339
12

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Kıvanç Birsoy, Tim Wang, Walter W Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M Sabatini. Cell 2015
557
12

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism.
Hongyun Zhao, Lifeng Yang, Joelle Baddour, Abhinav Achreja, Vincent Bernard, Tyler Moss, Juan C Marini, Thavisha Tudawe, Elena G Seviour, F Anthony San Lucas,[...]. Elife 2016
418
12

Reductive carboxylation supports redox homeostasis during anchorage-independent growth.
Lei Jiang, Alexander A Shestov, Pamela Swain, Chendong Yang, Seth J Parker, Qiong A Wang, Lance S Terada, Nicholas D Adams, Michael T McCabe, Beth Pietrak,[...]. Nature 2016
272
11

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors.
Anneleen Daemen, David Peterson, Nisebita Sahu, Ron McCord, Xiangnan Du, Bonnie Liu, Katarzyna Kowanetz, Rebecca Hong, John Moffat, Min Gao,[...]. Proc Natl Acad Sci U S A 2015
157
11

Regulation of cancer cell metabolism.
Rob A Cairns, Isaac S Harris, Tak W Mak. Nat Rev Cancer 2011
11

Aspartate is an endogenous metabolic limitation for tumour growth.
Lucas B Sullivan, Alba Luengo, Laura V Danai, Lauren N Bush, Frances F Diehl, Aaron M Hosios, Allison N Lau, Sarah Elmiligy, Scott Malstrom, Caroline A Lewis,[...]. Nat Cell Biol 2018
114
11

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.
Anne Le, Andrew N Lane, Max Hamaker, Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J Rojas, Barbara S Slusher, Haixia Zhang,[...]. Cell Metab 2012
644
11

Targeting mitochondrial glutaminase activity inhibits oncogenic transformation.
Jian-Bin Wang, Jon W Erickson, Reina Fuji, Sekar Ramachandran, Ping Gao, Ramani Dinavahi, Kristin F Wilson, Andre L B Ambrosio, Sandra M G Dias, Chi V Dang,[...]. Cancer Cell 2010
527
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.