Yoshiharu Muto, Masaaki Nishiyama, Akihiro Nita, Toshiro Moroishi, Keiichi I Nakayama. Nat Commun 2017
Times Cited: 34
Times Cited: 34
Times Cited
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Similarity
Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice.
Xin Jin, Xiaoyuan He, Xiaoli Cao, Ping Xu, Yi Xing, Songnan Sui, Luqiao Wang, Juanxia Meng, Wenyi Lu, Rui Cui,[...]. Haematologica 2018
Xin Jin, Xiaoyuan He, Xiaoli Cao, Ping Xu, Yi Xing, Songnan Sui, Luqiao Wang, Juanxia Meng, Wenyi Lu, Rui Cui,[...]. Haematologica 2018
23
Two to tango: regulation of Mammalian iron metabolism.
Matthias W Hentze, Martina U Muckenthaler, Bruno Galy, Clara Camaschella. Cell 2010
Matthias W Hentze, Martina U Muckenthaler, Bruno Galy, Clara Camaschella. Cell 2010
17
The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo.
Toshiro Moroishi, Masaaki Nishiyama, Yukiko Takeda, Kazuhiro Iwai, Keiichi I Nakayama. Cell Metab 2011
Toshiro Moroishi, Masaaki Nishiyama, Yukiko Takeda, Kazuhiro Iwai, Keiichi I Nakayama. Cell Metab 2011
17
ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice.
Xiao Chai, Deguan Li, Xiaoli Cao, Yuchen Zhang, Juan Mu, Wenyi Lu, Xia Xiao, Chengcheng Li, Juanxia Meng, Jie Chen,[...]. Sci Rep 2015
Xiao Chai, Deguan Li, Xiaoli Cao, Yuchen Zhang, Juan Mu, Wenyi Lu, Xia Xiao, Chengcheng Li, Juanxia Meng, Jie Chen,[...]. Sci Rep 2015
14
An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis.
Ameen A Salahudeen, Joel W Thompson, Julio C Ruiz, He-Wen Ma, Lisa N Kinch, Qiming Li, Nick V Grishin, Richard K Bruick. Science 2009
Ameen A Salahudeen, Joel W Thompson, Julio C Ruiz, He-Wen Ma, Lisa N Kinch, Qiming Li, Nick V Grishin, Richard K Bruick. Science 2009
14
Ferroptosis: an iron-dependent form of nonapoptotic cell death.
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
14
Identification of erythroferrone as an erythroid regulator of iron metabolism.
Léon Kautz, Grace Jung, Erika V Valore, Stefano Rivella, Elizabeta Nemeth, Tomas Ganz. Nat Genet 2014
Léon Kautz, Grace Jung, Erika V Valore, Stefano Rivella, Elizabeta Nemeth, Tomas Ganz. Nat Genet 2014
14
Free iron catalyzes oxidative damage to hematopoietic cells/mesenchymal stem cells in vitro and suppresses hematopoiesis in iron overload patients.
Wenyi Lu, Mingfeng Zhao, Sajin Rajbhandary, Fang Xie, Xiao Chai, Juan Mu, Juanxia Meng, Yongjun Liu, Yan Jiang, Xinnv Xu,[...]. Eur J Haematol 2013
Wenyi Lu, Mingfeng Zhao, Sajin Rajbhandary, Fang Xie, Xiao Chai, Juan Mu, Juanxia Meng, Yongjun Liu, Yan Jiang, Xinnv Xu,[...]. Eur J Haematol 2013
11
11
Control of iron homeostasis by an iron-regulated ubiquitin ligase.
Ajay A Vashisht, Kimberly B Zumbrennen, Xinhua Huang, David N Powers, Armando Durazo, Dahui Sun, Nimesh Bhaskaran, Anja Persson, Mathias Uhlen, Olle Sangfelt,[...]. Science 2009
Ajay A Vashisht, Kimberly B Zumbrennen, Xinhua Huang, David N Powers, Armando Durazo, Dahui Sun, Nimesh Bhaskaran, Anja Persson, Mathias Uhlen, Olle Sangfelt,[...]. Science 2009
11
The IRP/IRE system in vivo: insights from mouse models.
Nicole Wilkinson, Kostas Pantopoulos. Front Pharmacol 2014
Nicole Wilkinson, Kostas Pantopoulos. Front Pharmacol 2014
11
Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability.
Rosa Viñas-Castells, Álex Frías, Estefanía Robles-Lanuza, Kun Zhang, Gregory D Longmore, Antonio García de Herreros, Víctor M Díaz. Nucleic Acids Res 2014
Rosa Viñas-Castells, Álex Frías, Estefanía Robles-Lanuza, Kun Zhang, Gregory D Longmore, Antonio García de Herreros, Víctor M Díaz. Nucleic Acids Res 2014
11
Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression.
Chia-Hsin Chan, John Kenneth Morrow, Chien-Feng Li, Yuan Gao, Guoxiang Jin, Asad Moten, Loren J Stagg, John E Ladbury, Zhen Cai, Dazhi Xu,[...]. Cell 2013
Chia-Hsin Chan, John Kenneth Morrow, Chien-Feng Li, Yuan Gao, Guoxiang Jin, Asad Moten, Loren J Stagg, John E Ladbury, Zhen Cai, Dazhi Xu,[...]. Cell 2013
11
FBXL5 modulates HIF-1α transcriptional activity by degradation of CITED2.
Gisela Machado-Oliveira, Eduarda Guerreiro, Ana Catarina Matias, João Facucho-Oliveira, Ivette Pacheco-Leyva, José Bragança. Arch Biochem Biophys 2015
Gisela Machado-Oliveira, Eduarda Guerreiro, Ana Catarina Matias, João Facucho-Oliveira, Ivette Pacheco-Leyva, José Bragança. Arch Biochem Biophys 2015
25
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer.
David Frescas, Michele Pagano. Nat Rev Cancer 2008
David Frescas, Michele Pagano. Nat Rev Cancer 2008
11
Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex.
Douglas I Lin, Olena Barbash, K G Suresh Kumar, Jason D Weber, J Wade Harper, Andres J P Klein-Szanto, Anil Rustgi, Serge Y Fuchs, J Alan Diehl. Mol Cell 2006
Douglas I Lin, Olena Barbash, K G Suresh Kumar, Jason D Weber, J Wade Harper, Andres J P Klein-Szanto, Anil Rustgi, Serge Y Fuchs, J Alan Diehl. Mol Cell 2006
11
A Red Carpet for Iron Metabolism.
Martina U Muckenthaler, Stefano Rivella, Matthias W Hentze, Bruno Galy. Cell 2017
Martina U Muckenthaler, Stefano Rivella, Matthias W Hentze, Bruno Galy. Cell 2017
11
FBXL12 regulates T-cell differentiation in a cell-autonomous manner.
Akihiro Nita, Masaaki Nishiyama, Yoshiharu Muto, Keiichi I Nakayama. Genes Cells 2016
Akihiro Nita, Masaaki Nishiyama, Yoshiharu Muto, Keiichi I Nakayama. Genes Cells 2016
80
Effects of iron overload on the bone marrow microenvironment in mice.
Yuchen Zhang, Wenjing Zhai, Mingfeng Zhao, Deguan Li, Xiao Chai, Xiaoli Cao, Juanxia Meng, Jie Chen, Xia Xiao, Qing Li,[...]. PLoS One 2015
Yuchen Zhang, Wenjing Zhai, Mingfeng Zhao, Deguan Li, Xiao Chai, Xiaoli Cao, Juanxia Meng, Jie Chen, Xia Xiao, Qing Li,[...]. PLoS One 2015
8
Iron overload promotes mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/MFF/Drp1 pathway.
Qingqing Zheng, Youshan Zhao, Juan Guo, Sida Zhao, Chengming Fei, Chao Xiao, Dong Wu, Lingyun Wu, Xiao Li, Chunkang Chang. Cell Death Dis 2018
Qingqing Zheng, Youshan Zhao, Juan Guo, Sida Zhao, Chengming Fei, Chao Xiao, Dong Wu, Lingyun Wu, Xiao Li, Chunkang Chang. Cell Death Dis 2018
8
The second transferrin receptor regulates red blood cell production in mice.
Antonella Nai, Maria Rosa Lidonnici, Marco Rausa, Giacomo Mandelli, Alessia Pagani, Laura Silvestri, Giuliana Ferrari, Clara Camaschella. Blood 2015
Antonella Nai, Maria Rosa Lidonnici, Marco Rausa, Giacomo Mandelli, Alessia Pagani, Laura Silvestri, Giuliana Ferrari, Clara Camaschella. Blood 2015
8
Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.
Manik C Ghosh, De-Liang Zhang, Suh Young Jeong, Gennadiy Kovtunovych, Hayden Ollivierre-Wilson, Audrey Noguchi, Tiffany Tu, Thomas Senecal, Gabrielle Robinson, Daniel R Crooks,[...]. Cell Metab 2013
Manik C Ghosh, De-Liang Zhang, Suh Young Jeong, Gennadiy Kovtunovych, Hayden Ollivierre-Wilson, Audrey Noguchi, Tiffany Tu, Thomas Senecal, Gabrielle Robinson, Daniel R Crooks,[...]. Cell Metab 2013
8
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.
Brent R Stockwell, José Pedro Friedmann Angeli, Hülya Bayir, Ashley I Bush, Marcus Conrad, Scott J Dixon, Simone Fulda, Sergio Gascón, Stavroula K Hatzios, Valerian E Kagan,[...]. Cell 2017
Brent R Stockwell, José Pedro Friedmann Angeli, Hülya Bayir, Ashley I Bush, Marcus Conrad, Scott J Dixon, Simone Fulda, Sergio Gascón, Stavroula K Hatzios, Valerian E Kagan,[...]. Cell 2017
8
The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption.
Sheila A Anderson, Christopher P Nizzi, Yuan-I Chang, Kathryn M Deck, Paul J Schmidt, Bruno Galy, Alisa Damnernsawad, Aimee T Broman, Christina Kendziorski, Matthias W Hentze,[...]. Cell Metab 2013
Sheila A Anderson, Christopher P Nizzi, Yuan-I Chang, Kathryn M Deck, Paul J Schmidt, Bruno Galy, Alisa Damnernsawad, Aimee T Broman, Christina Kendziorski, Matthias W Hentze,[...]. Cell Metab 2013
8
Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency.
Mayka Sanchez, Bruno Galy, Martina U Muckenthaler, Matthias W Hentze. Nat Struct Mol Biol 2007
Mayka Sanchez, Bruno Galy, Martina U Muckenthaler, Matthias W Hentze. Nat Struct Mol Biol 2007
8
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis.
Esther G Meyron-Holtz, Manik C Ghosh, Kazuhiro Iwai, Timothy LaVaute, Xavier Brazzolotto, Urs V Berger, William Land, Hayden Ollivierre-Wilson, Alex Grinberg, Paul Love,[...]. EMBO J 2004
Esther G Meyron-Holtz, Manik C Ghosh, Kazuhiro Iwai, Timothy LaVaute, Xavier Brazzolotto, Urs V Berger, William Land, Hayden Ollivierre-Wilson, Alex Grinberg, Paul Love,[...]. EMBO J 2004
8
FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.
Takayoshi Yamauchi, Masaaki Nishiyama, Toshiro Moroishi, Atsuki Kawamura, Keiichi I Nakayama. Mol Cell Biol 2017
Takayoshi Yamauchi, Masaaki Nishiyama, Toshiro Moroishi, Atsuki Kawamura, Keiichi I Nakayama. Mol Cell Biol 2017
23
Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms.
Srinivas Chollangi, Joel W Thompson, Julio C Ruiz, Kevin H Gardner, Richard K Bruick. J Biol Chem 2012
Srinivas Chollangi, Joel W Thompson, Julio C Ruiz, Kevin H Gardner, Richard K Bruick. J Biol Chem 2012
11
FBXL5 attenuates RhoGDI2-induced cisplatin resistance in gastric cancer cells.
W-D Wu, M Wang, H-H Ding, Z-J Qiu. Eur Rev Med Pharmacol Sci 2016
W-D Wu, M Wang, H-H Ding, Z-J Qiu. Eur Rev Med Pharmacol Sci 2016
17
FBXL5 inhibits metastasis of gastric cancer through suppressing Snail1.
Weidong Wu, Honghua Ding, Jun Cao, Weihao Zhang. Cell Physiol Biochem 2015
Weidong Wu, Honghua Ding, Jun Cao, Weihao Zhang. Cell Physiol Biochem 2015
8
FBXL5 interacts with p150Glued and regulates its ubiquitination.
Ning Zhang, Jing Liu, Xia Ding, Felix Aikhionbare, Changjiang Jin, Xuebiao Yao. Biochem Biophys Res Commun 2007
Ning Zhang, Jing Liu, Xia Ding, Felix Aikhionbare, Changjiang Jin, Xuebiao Yao. Biochem Biophys Res Commun 2007
16
FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response.
Zhi-Wei Chen, Bin Liu, Nai-Wang Tang, Yun-Hua Xu, Xiang-Yun Ye, Zi-Ming Li, Xiao-Min Niu, Sheng-Ping Shen, Shun Lu, Ling Xu. Nucleic Acids Res 2014
Zhi-Wei Chen, Bin Liu, Nai-Wang Tang, Yun-Hua Xu, Xiang-Yun Ye, Zi-Ming Li, Xiao-Min Niu, Sheng-Ping Shen, Shun Lu, Ling Xu. Nucleic Acids Res 2014
11
FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes.
Arisa Hirano, Kanae Yumimoto, Ryosuke Tsunematsu, Masaki Matsumoto, Masaaki Oyama, Hiroko Kozuka-Hata, Tomoki Nakagawa, Darin Lanjakornsiripan, Keiichi I Nakayama, Yoshitaka Fukada. Cell 2013
Arisa Hirano, Kanae Yumimoto, Ryosuke Tsunematsu, Masaki Matsumoto, Masaaki Oyama, Hiroko Kozuka-Hata, Tomoki Nakagawa, Darin Lanjakornsiripan, Keiichi I Nakayama, Yoshitaka Fukada. Cell 2013
8
The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation.
Laura Pontano Vaites, Eric K Lee, Zhaorui Lian, Olena Barbash, Darshan Roy, Mariusz Wasik, Andres J P Klein-Szanto, Anil K Rustgi, J Alan Diehl. Mol Cell Biol 2011
Laura Pontano Vaites, Eric K Lee, Zhaorui Lian, Olena Barbash, Darshan Roy, Mariusz Wasik, Andres J P Klein-Szanto, Anil K Rustgi, J Alan Diehl. Mol Cell Biol 2011
8
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins.
Luca Busino, Florian Bassermann, Alessio Maiolica, Choogon Lee, Patrick M Nolan, Sofia I H Godinho, Giulio F Draetta, Michele Pagano. Science 2007
Luca Busino, Florian Bassermann, Alessio Maiolica, Choogon Lee, Patrick M Nolan, Sofia I H Godinho, Giulio F Draetta, Michele Pagano. Science 2007
8
Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.
Sandra M Siepka, Seung-Hee Yoo, Junghea Park, Weimin Song, Vivek Kumar, Yinin Hu, Choogon Lee, Joseph S Takahashi. Cell 2007
Sandra M Siepka, Seung-Hee Yoo, Junghea Park, Weimin Song, Vivek Kumar, Yinin Hu, Choogon Lee, Joseph S Takahashi. Cell 2007
8
Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.
Ichiro Onoyama, Ryosuke Tsunematsu, Akinobu Matsumoto, Taichi Kimura, Ignacio Moreno de Alborán, Keiko Nakayama, Keiichi I Nakayama. J Exp Med 2007
Ichiro Onoyama, Ryosuke Tsunematsu, Akinobu Matsumoto, Taichi Kimura, Ignacio Moreno de Alborán, Keiko Nakayama, Keiichi I Nakayama. J Exp Med 2007
8
SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama, Daming Gao, Alan Tseng, Richard S Maser, Bo Zhai, Lixin Wan, Alejandro Gutierrez, Alan W Lau,[...]. Nature 2011
Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama, Daming Gao, Alan Tseng, Richard S Maser, Bo Zhai, Lixin Wan, Alejandro Gutierrez, Alan W Lau,[...]. Nature 2011
8
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.
Sahoko Matsuoka, Yuichi Oike, Ichiro Onoyama, Atsushi Iwama, Fumio Arai, Keiyo Takubo, Yoichi Mashimo, Hideyuki Oguro, Eriko Nitta, Keisuke Ito,[...]. Genes Dev 2008
Sahoko Matsuoka, Yuichi Oike, Ichiro Onoyama, Atsushi Iwama, Fumio Arai, Keiyo Takubo, Yoichi Mashimo, Hideyuki Oguro, Eriko Nitta, Keisuke Ito,[...]. Genes Dev 2008
8
Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains.
Yukiko Yoshida, Fuminori Tokunaga, Tomoki Chiba, Kazuhiro Iwai, Keiji Tanaka, Tadashi Tai. J Biol Chem 2003
Yukiko Yoshida, Fuminori Tokunaga, Tomoki Chiba, Kazuhiro Iwai, Keiji Tanaka, Tadashi Tai. J Biol Chem 2003
8
Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7.
Benjamin J Thompson, Vladimir Jankovic, Jie Gao, Silvia Buonamici, Alan Vest, Jennifer May Lee, Jiri Zavadil, Stephen D Nimer, Iannis Aifantis. J Exp Med 2008
Benjamin J Thompson, Vladimir Jankovic, Jie Gao, Silvia Buonamici, Alan Vest, Jennifer May Lee, Jiri Zavadil, Stephen D Nimer, Iannis Aifantis. J Exp Med 2008
8
F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage.
Manas K Santra, Narendra Wajapeyee, Michael R Green. Nature 2009
Manas K Santra, Narendra Wajapeyee, Michael R Green. Nature 2009
8
FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
Roya Babaei-Jadidi, Ningning Li, Anas Saadeddin, Bradley Spencer-Dene, Anett Jandke, Belal Muhammad, ElSayed E Ibrahim, Ranjithmenon Muraleedharan, Mohammed Abuzinadah, Hayley Davis,[...]. J Exp Med 2011
Roya Babaei-Jadidi, Ningning Li, Anas Saadeddin, Bradley Spencer-Dene, Anett Jandke, Belal Muhammad, ElSayed E Ibrahim, Ranjithmenon Muraleedharan, Mohammed Abuzinadah, Hayley Davis,[...]. J Exp Med 2011
8
The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period.
Sofia I H Godinho, Elizabeth S Maywood, Linda Shaw, Valter Tucci, Alun R Barnard, Luca Busino, Michele Pagano, Rachel Kendall, Mohamed M Quwailid, M Rosario Romero,[...]. Science 2007
Sofia I H Godinho, Elizabeth S Maywood, Linda Shaw, Valter Tucci, Alun R Barnard, Luca Busino, Michele Pagano, Rachel Kendall, Mohamed M Quwailid, M Rosario Romero,[...]. Science 2007
8
Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression.
Linsey Reavie, Shannon M Buckley, Evangelia Loizou, Shoichiro Takeishi, Beatriz Aranda-Orgilles, Delphine Ndiaye-Lobry, Omar Abdel-Wahab, Sherif Ibrahim, Keiichi I Nakayama, Iannis Aifantis. Cancer Cell 2013
Linsey Reavie, Shannon M Buckley, Evangelia Loizou, Shoichiro Takeishi, Beatriz Aranda-Orgilles, Delphine Ndiaye-Lobry, Omar Abdel-Wahab, Sherif Ibrahim, Keiichi I Nakayama, Iannis Aifantis. Cancer Cell 2013
8
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.
Hui-Kuan Lin, Zhenbang Chen, Guocan Wang, Caterina Nardella, Szu-Wei Lee, Chia-Hsin Chan, Wei-Lei Yang, Jing Wang, Ainara Egia, Keiichi I Nakayama,[...]. Nature 2010
Hui-Kuan Lin, Zhenbang Chen, Guocan Wang, Caterina Nardella, Szu-Wei Lee, Chia-Hsin Chan, Wei-Lei Yang, Jing Wang, Ainara Egia, Keiichi I Nakayama,[...]. Nature 2010
8
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation.
Anne Wilson, Mark J Murphy, Thordur Oskarsson, Konstantinos Kaloulis, Michael D Bettess, Gabriela M Oser, Anne-Catherine Pasche, Christian Knabenhans, H Robson Macdonald, Andreas Trumpp. Genes Dev 2004
Anne Wilson, Mark J Murphy, Thordur Oskarsson, Konstantinos Kaloulis, Michael D Bettess, Gabriela M Oser, Anne-Catherine Pasche, Christian Knabenhans, H Robson Macdonald, Andreas Trumpp. Genes Dev 2004
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.