Olivia C Küster, Daria Laptinskaya, Patrick Fissler, Cathrin Schnack, Martina Zügel, Verena Nold, Franka Thurm, Sina Pleiner, Alexander Karabatsiakis, Björn von Einem, Patrick Weydt, André Liesener, Andreas Borta, Alexander Woll, Bastian Hengerer, Iris-Tatjana Kolassa, Christine A F von Arnim. J Alzheimers Dis 2017
Times Cited: 49
Times Cited: 49
Times Cited
Times Co-cited
Similarity
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Pontus Boström, Jun Wu, Mark P Jedrychowski, Anisha Korde, Li Ye, James C Lo, Kyle A Rasbach, Elisabeth Almer Boström, Jang Hyun Choi, Jonathan Z Long,[...]. Nature 2012
Pontus Boström, Jun Wu, Mark P Jedrychowski, Anisha Korde, Li Ye, James C Lo, Kyle A Rasbach, Elisabeth Almer Boström, Jang Hyun Choi, Jonathan Z Long,[...]. Nature 2012
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Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway.
Christiane D Wrann, James P White, John Salogiannnis, Dina Laznik-Bogoslavski, Jun Wu, Di Ma, Jiandie D Lin, Michael E Greenberg, Bruce M Spiegelman. Cell Metab 2013
Christiane D Wrann, James P White, John Salogiannnis, Dina Laznik-Bogoslavski, Jun Wu, Di Ma, Jiandie D Lin, Michael E Greenberg, Bruce M Spiegelman. Cell Metab 2013
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Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.
Mychael V Lourenco, Rudimar L Frozza, Guilherme B de Freitas, Hong Zhang, Grasielle C Kincheski, Felipe C Ribeiro, Rafaella A Gonçalves, Julia R Clarke, Danielle Beckman, Agnieszka Staniszewski,[...]. Nat Med 2019
Mychael V Lourenco, Rudimar L Frozza, Guilherme B de Freitas, Hong Zhang, Grasielle C Kincheski, Felipe C Ribeiro, Rafaella A Gonçalves, Julia R Clarke, Danielle Beckman, Agnieszka Staniszewski,[...]. Nat Med 2019
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Exercise training increases size of hippocampus and improves memory.
Kirk I Erickson, Michelle W Voss, Ruchika Shaurya Prakash, Chandramallika Basak, Amanda Szabo, Laura Chaddock, Jennifer S Kim, Susie Heo, Heloisa Alves, Siobhan M White,[...]. Proc Natl Acad Sci U S A 2011
Kirk I Erickson, Michelle W Voss, Ruchika Shaurya Prakash, Chandramallika Basak, Amanda Szabo, Laura Chaddock, Jennifer S Kim, Susie Heo, Heloisa Alves, Siobhan M White,[...]. Proc Natl Acad Sci U S A 2011
20
Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry.
Mark P Jedrychowski, Christiane D Wrann, Joao A Paulo, Kaitlyn K Gerber, John Szpyt, Matthew M Robinson, K Sreekumaran Nair, Steven P Gygi, Bruce M Spiegelman. Cell Metab 2015
Mark P Jedrychowski, Christiane D Wrann, Joao A Paulo, Kaitlyn K Gerber, John Szpyt, Matthew M Robinson, K Sreekumaran Nair, Steven P Gygi, Bruce M Spiegelman. Cell Metab 2015
20
The novel exercise-induced hormone irisin protects against neuronal injury via activation of the Akt and ERK1/2 signaling pathways and contributes to the neuroprotection of physical exercise in cerebral ischemia.
Dong-Jie Li, Yong-Hua Li, Hong-Bin Yuan, Le-Feng Qu, Pei Wang. Metabolism 2017
Dong-Jie Li, Yong-Hua Li, Hong-Bin Yuan, Le-Feng Qu, Pei Wang. Metabolism 2017
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Irisin - a myth rather than an exercise-inducible myokine.
Elke Albrecht, Frode Norheim, Bernd Thiede, Torgeir Holen, Tomoo Ohashi, Lisa Schering, Sindre Lee, Julia Brenmoehl, Selina Thomas, Christian A Drevon,[...]. Sci Rep 2015
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16
Physiology and role of irisin in glucose homeostasis.
Nikolaos Perakakis, Georgios A Triantafyllou, José Manuel Fernández-Real, Joo Young Huh, Kyung Hee Park, Jochen Seufert, Christos S Mantzoros. Nat Rev Endocrinol 2017
Nikolaos Perakakis, Georgios A Triantafyllou, José Manuel Fernández-Real, Joo Young Huh, Kyung Hee Park, Jochen Seufert, Christos S Mantzoros. Nat Rev Endocrinol 2017
14
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.
Hyeonwoo Kim, Christiane D Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A Parkman, Scott J Novick,[...]. Cell 2018
Hyeonwoo Kim, Christiane D Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A Parkman, Scott J Novick,[...]. Cell 2018
14
A role for FNDC5/Irisin in the beneficial effects of exercise on the brain and in neurodegenerative diseases.
Michael F Young, Sophia Valaris, Christiane D Wrann. Prog Cardiovasc Dis 2019
Michael F Young, Sophia Valaris, Christiane D Wrann. Prog Cardiovasc Dis 2019
15
Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance.
José María Moreno-Navarrete, Francisco Ortega, Marta Serrano, Ester Guerra, Gerard Pardo, Francisco Tinahones, Wifredo Ricart, José Manuel Fernández-Real. J Clin Endocrinol Metab 2013
José María Moreno-Navarrete, Francisco Ortega, Marta Serrano, Ester Guerra, Gerard Pardo, Francisco Tinahones, Wifredo Ricart, José Manuel Fernández-Real. J Clin Endocrinol Metab 2013
14
The effects of acute and chronic exercise on PGC-1α, irisin and browning of subcutaneous adipose tissue in humans.
Frode Norheim, Torgrim Mikal Langleite, Marit Hjorth, Torgeir Holen, Anders Kielland, Hans Kristian Stadheim, Hanne Løvdal Gulseth, Kåre Inge Birkeland, Jørgen Jensen, Christian A Drevon. FEBS J 2014
Frode Norheim, Torgrim Mikal Langleite, Marit Hjorth, Torgeir Holen, Anders Kielland, Hans Kristian Stadheim, Hanne Løvdal Gulseth, Kåre Inge Birkeland, Jørgen Jensen, Christian A Drevon. FEBS J 2014
12
Serum irisin levels are regulated by acute strenuous exercise.
Dennis Löffler, Ulrike Müller, Kathrin Scheuermann, Daniela Friebe, Julia Gesing, Julia Bielitz, Sandra Erbs, Kathrin Landgraf, Isabel Viola Wagner, Wieland Kiess,[...]. J Clin Endocrinol Metab 2015
Dennis Löffler, Ulrike Müller, Kathrin Scheuermann, Daniela Friebe, Julia Gesing, Julia Bielitz, Sandra Erbs, Kathrin Landgraf, Isabel Viola Wagner, Wieland Kiess,[...]. J Clin Endocrinol Metab 2015
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Transport of brain-derived neurotrophic factor across the blood-brain barrier.
W Pan, W A Banks, M B Fasold, J Bluth, A J Kastin. Neuropharmacology 1998
W Pan, W A Banks, M B Fasold, J Bluth, A J Kastin. Neuropharmacology 1998
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"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.
M F Folstein, S E Folstein, P R McHugh. J Psychiatr Res 1975
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Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health.
Igor Cervenka, Leandro Z Agudelo, Jorge L Ruas. Science 2017
Igor Cervenka, Leandro Z Agudelo, Jorge L Ruas. Science 2017
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Detection and quantitation of irisin in human cerebrospinal fluid by tandem mass spectrometry.
Qingwei Ruan, Limin Zhang, Jian Ruan, Xixue Zhang, Jie Chen, Cheng Ma, Zhuowei Yu. Peptides 2018
Qingwei Ruan, Limin Zhang, Jian Ruan, Xixue Zhang, Jie Chen, Cheng Ma, Zhuowei Yu. Peptides 2018
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Pharmacological concentrations of irisin increase cell proliferation without influencing markers of neurite outgrowth and synaptogenesis in mouse H19-7 hippocampal cell lines.
Hyun-Seuk Moon, Fadime Dincer, Christos S Mantzoros. Metabolism 2013
Hyun-Seuk Moon, Fadime Dincer, Christos S Mantzoros. Metabolism 2013
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BDNF Responses in Healthy Older Persons to 35 Minutes of Physical Exercise, Cognitive Training, and Mindfulness: Associations with Working Memory Function.
Krister Håkansson, Aurélie Ledreux, Kirk Daffner, Yvonne Terjestam, Patrick Bergman, Roger Carlsson, Miia Kivipelto, Bengt Winblad, Ann-Charlotte Granholm, Abdul Kadir H Mohammed. J Alzheimers Dis 2017
Krister Håkansson, Aurélie Ledreux, Kirk Daffner, Yvonne Terjestam, Patrick Bergman, Roger Carlsson, Miia Kivipelto, Bengt Winblad, Ann-Charlotte Granholm, Abdul Kadir H Mohammed. J Alzheimers Dis 2017
12
FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise.
Joo Young Huh, Grigorios Panagiotou, Vassilis Mougios, Mary Brinkoetter, Maria T Vamvini, Benjamin E Schneider, Christos S Mantzoros. Metabolism 2012
Joo Young Huh, Grigorios Panagiotou, Vassilis Mougios, Mary Brinkoetter, Maria T Vamvini, Benjamin E Schneider, Christos S Mantzoros. Metabolism 2012
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Neuroplasticity - exercise-induced response of peripheral brain-derived neurotrophic factor: a systematic review of experimental studies in human subjects.
Kristel Knaepen, Maaike Goekint, Elsa Marie Heyman, Romain Meeusen. Sports Med 2010
Kristel Knaepen, Maaike Goekint, Elsa Marie Heyman, Romain Meeusen. Sports Med 2010
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Evidence for a release of brain-derived neurotrophic factor from the brain during exercise.
Peter Rasmussen, Patrice Brassard, Helle Adser, Martin V Pedersen, Lotte Leick, Emma Hart, Niels H Secher, Bente K Pedersen, Henriette Pilegaard. Exp Physiol 2009
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Exercise builds brain health: key roles of growth factor cascades and inflammation.
Carl W Cotman, Nicole C Berchtold, Lori-Ann Christie. Trends Neurosci 2007
Carl W Cotman, Nicole C Berchtold, Lori-Ann Christie. Trends Neurosci 2007
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Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans.
Maja Schlittler, Michel Goiny, Leandro Z Agudelo, Tomas Venckunas, Marius Brazaitis, Albertas Skurvydas, Sigitas Kamandulis, Jorge L Ruas, Sophie Erhardt, Håkan Westerblad,[...]. Am J Physiol Cell Physiol 2016
Maja Schlittler, Michel Goiny, Leandro Z Agudelo, Tomas Venckunas, Marius Brazaitis, Albertas Skurvydas, Sigitas Kamandulis, Jorge L Ruas, Sophie Erhardt, Håkan Westerblad,[...]. Am J Physiol Cell Physiol 2016
10
Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression.
Leandro Z Agudelo, Teresa Femenía, Funda Orhan, Margareta Porsmyr-Palmertz, Michel Goiny, Vicente Martinez-Redondo, Jorge C Correia, Manizheh Izadi, Maria Bhat, Ina Schuppe-Koistinen,[...]. Cell 2014
Leandro Z Agudelo, Teresa Femenía, Funda Orhan, Margareta Porsmyr-Palmertz, Michel Goiny, Vicente Martinez-Redondo, Jorge C Correia, Manizheh Izadi, Maria Bhat, Ina Schuppe-Koistinen,[...]. Cell 2014
10
Direct effects of exercise on kynurenine metabolism in people with normal glucose tolerance or type 2 diabetes.
Jonathan M Mudry, Petter S Alm, Sophie Erhardt, Michel Goiny, Tomas Fritz, Kenneth Caidahl, Juleen R Zierath, Anna Krook, Harriet Wallberg-Henriksson. Diabetes Metab Res Rev 2016
Jonathan M Mudry, Petter S Alm, Sophie Erhardt, Michel Goiny, Tomas Fritz, Kenneth Caidahl, Juleen R Zierath, Anna Krook, Harriet Wallberg-Henriksson. Diabetes Metab Res Rev 2016
16
Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling.
Yuan Zhang, Rui Li, Yan Meng, Shiwu Li, William Donelan, Yan Zhao, Lei Qi, Mingxiang Zhang, Xingli Wang, Taixing Cui,[...]. Diabetes 2014
Yuan Zhang, Rui Li, Yan Meng, Shiwu Li, William Donelan, Yan Zhao, Lei Qi, Mingxiang Zhang, Xingli Wang, Taixing Cui,[...]. Diabetes 2014
10
The relationship between brain-derived neurotrophic factor, irisin and cognitive skills of endurance athletes.
Muaz Belviranli, Nilsel Okudan, Banu Kabak, Murat Erdoğan, Muharrem Karanfilci. Phys Sportsmed 2016
Muaz Belviranli, Nilsel Okudan, Banu Kabak, Murat Erdoğan, Muharrem Karanfilci. Phys Sportsmed 2016
15
Evidence against a beneficial effect of irisin in humans.
Silja Raschke, Manuela Elsen, Hans Gassenhuber, Mark Sommerfeld, Uwe Schwahn, Barbara Brockmann, Raphael Jung, Ulrik Wisløff, Arnt E Tjønna, Truls Raastad,[...]. PLoS One 2013
Silja Raschke, Manuela Elsen, Hans Gassenhuber, Mark Sommerfeld, Uwe Schwahn, Barbara Brockmann, Raphael Jung, Ulrik Wisløff, Arnt E Tjønna, Truls Raastad,[...]. PLoS One 2013
10
FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle.
B M Varela-Rodríguez, L Pena-Bello, P Juiz-Valiña, B Vidal-Bretal, F Cordido, S Sangiao-Alvarellos. Sci Rep 2016
B M Varela-Rodríguez, L Pena-Bello, P Juiz-Valiña, B Vidal-Bretal, F Cordido, S Sangiao-Alvarellos. Sci Rep 2016
10
Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans.
Paul Lee, Joyce D Linderman, Sheila Smith, Robert J Brychta, Juan Wang, Christopher Idelson, Rachel M Perron, Charlotte D Werner, Giao Q Phan, Udai S Kammula,[...]. Cell Metab 2014
Paul Lee, Joyce D Linderman, Sheila Smith, Robert J Brychta, Juan Wang, Christopher Idelson, Rachel M Perron, Charlotte D Werner, Giao Q Phan, Udai S Kammula,[...]. Cell Metab 2014
10
The structure of irisin reveals a novel intersubunit β-sheet fibronectin type III (FNIII) dimer: implications for receptor activation.
Maria A Schumacher, Nagababu Chinnam, Tomoo Ohashi, Riddhi Sanjay Shah, Harold P Erickson. J Biol Chem 2013
Maria A Schumacher, Nagababu Chinnam, Tomoo Ohashi, Riddhi Sanjay Shah, Harold P Erickson. J Biol Chem 2013
10
Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies.
Timea Kurdiova, Miroslav Balaz, Marek Vician, Denisa Maderova, Miroslav Vlcek, Ladislav Valkovic, Miroslav Srbecky, Richard Imrich, Olga Kyselovicova, Vitazoslav Belan,[...]. J Physiol 2014
Timea Kurdiova, Miroslav Balaz, Marek Vician, Denisa Maderova, Miroslav Vlcek, Ladislav Valkovic, Miroslav Srbecky, Richard Imrich, Olga Kyselovicova, Vitazoslav Belan,[...]. J Physiol 2014
10
FNDC5/irisin is not only a myokine but also an adipokine.
Arturo Roca-Rivada, Cecilia Castelao, Lucía L Senin, María O Landrove, Javier Baltar, Ana Belén Crujeiras, Luisa María Seoane, Felipe F Casanueva, María Pardo. PLoS One 2013
Arturo Roca-Rivada, Cecilia Castelao, Lucía L Senin, María O Landrove, Javier Baltar, Ana Belén Crujeiras, Luisa María Seoane, Felipe F Casanueva, María Pardo. PLoS One 2013
10
The myokine irisin increases cortical bone mass.
Graziana Colaianni, Concetta Cuscito, Teresa Mongelli, Paolo Pignataro, Cinzia Buccoliero, Peng Liu, Ping Lu, Loris Sartini, Mariasevera Di Comite, Giorgio Mori,[...]. Proc Natl Acad Sci U S A 2015
Graziana Colaianni, Concetta Cuscito, Teresa Mongelli, Paolo Pignataro, Cinzia Buccoliero, Peng Liu, Ping Lu, Loris Sartini, Mariasevera Di Comite, Giorgio Mori,[...]. Proc Natl Acad Sci U S A 2015
10
Irisin in response to acute and chronic whole-body vibration exercise in humans.
Joo Young Huh, Vassilis Mougios, Athanasios Skraparlis, Athanasios Kabasakalis, Christos S Mantzoros. Metabolism 2014
Joo Young Huh, Vassilis Mougios, Athanasios Skraparlis, Athanasios Kabasakalis, Christos S Mantzoros. Metabolism 2014
8
Neurotrophin regulation of neural circuit development and function.
Hyungju Park, Mu-ming Poo. Nat Rev Neurosci 2013
Hyungju Park, Mu-ming Poo. Nat Rev Neurosci 2013
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Mouse PeP: a novel peroxisomal protein linked to myoblast differentiation and development.
Andreu Ferrer-Martínez, Pilar Ruiz-Lozano, Kenneth R Chien. Dev Dyn 2002
Andreu Ferrer-Martínez, Pilar Ruiz-Lozano, Kenneth R Chien. Dev Dyn 2002
8
Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?
Harold P Erickson. Adipocyte 2013
Harold P Erickson. Adipocyte 2013
8
The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function.
Lee T Ferris, James S Williams, Chwan-Li Shen. Med Sci Sports Exerc 2007
Lee T Ferris, James S Williams, Chwan-Li Shen. Med Sci Sports Exerc 2007
8
Metabolic signatures of exercise in human plasma.
Gregory D Lewis, Laurie Farrell, Malissa J Wood, Maryann Martinovic, Zoltan Arany, Glenn C Rowe, Amanda Souza, Susan Cheng, Elizabeth L McCabe, Elaine Yang,[...]. Sci Transl Med 2010
Gregory D Lewis, Laurie Farrell, Malissa J Wood, Maryann Martinovic, Zoltan Arany, Glenn C Rowe, Amanda Souza, Susan Cheng, Elizabeth L McCabe, Elaine Yang,[...]. Sci Transl Med 2010
8
Exercise affects symptom severity but not biological measures in depression and somatization - results on IL-6, neopterin, tryptophan, kynurenine and 5-HIAA.
Anika Hennings, Markus J Schwarz, Sabine Riemer, Theresa M Stapf, Verena B Selberdinger, Winfried Rief. Psychiatry Res 2013
Anika Hennings, Markus J Schwarz, Sabine Riemer, Theresa M Stapf, Verena B Selberdinger, Winfried Rief. Psychiatry Res 2013
14
Association between irisin and major chronic diseases: a review.
M C Gouveia, J P Vella, F R Cafeo, F L Affonso Fonseca, M R Bacci. Eur Rev Med Pharmacol Sci 2016
M C Gouveia, J P Vella, F R Cafeo, F L Affonso Fonseca, M R Bacci. Eur Rev Med Pharmacol Sci 2016
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Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition.
Shoshanna Vaynman, Zhe Ying, Fernando Gomez-Pinilla. Eur J Neurosci 2004
Shoshanna Vaynman, Zhe Ying, Fernando Gomez-Pinilla. Eur J Neurosci 2004
8
Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health?
Satu Pekkala, Petri K Wiklund, Juha J Hulmi, Juha P Ahtiainen, Mia Horttanainen, Eija Pöllänen, Kari A Mäkelä, Heikki Kainulainen, Keijo Häkkinen, Kai Nyman,[...]. J Physiol 2013
Satu Pekkala, Petri K Wiklund, Juha J Hulmi, Juha P Ahtiainen, Mia Horttanainen, Eija Pöllänen, Kari A Mäkelä, Heikki Kainulainen, Keijo Häkkinen, Kai Nyman,[...]. J Physiol 2013
8
Exercise-induced irisin secretion is independent of age or fitness level and increased irisin may directly modulate muscle metabolism through AMPK activation.
Joo Young Huh, Vassilis Mougios, Athanasios Kabasakalis, Ioannis Fatouros, Aikaterina Siopi, Ioannis I Douroudos, Andreas Filippaios, Grigorios Panagiotou, Kyung Hee Park, Christos S Mantzoros. J Clin Endocrinol Metab 2014
Joo Young Huh, Vassilis Mougios, Athanasios Kabasakalis, Ioannis Fatouros, Aikaterina Siopi, Ioannis I Douroudos, Andreas Filippaios, Grigorios Panagiotou, Kyung Hee Park, Christos S Mantzoros. J Clin Endocrinol Metab 2014
8
Irisin regulates the expression of BDNF and glycometabolism in diabetic rats.
Lingning Huang, Sunjie Yan, Li Luo, Liyong Yang. Mol Med Rep 2019
Lingning Huang, Sunjie Yan, Li Luo, Liyong Yang. Mol Med Rep 2019
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Acute and chronic effects of exercise on the kynurenine pathway in humans - A brief review and future perspectives.
Alan J Metcalfe, Christina Koliamitra, Florian Javelle, Wilhelm Bloch, Philipp Zimmer. Physiol Behav 2018
Alan J Metcalfe, Christina Koliamitra, Florian Javelle, Wilhelm Bloch, Philipp Zimmer. Physiol Behav 2018
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Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function.
Hyo Youl Moon, Andreas Becke, David Berron, Benjamin Becker, Nirnath Sah, Galit Benoni, Emma Janke, Susan T Lubejko, Nigel H Greig, Julie A Mattison,[...]. Cell Metab 2016
Hyo Youl Moon, Andreas Becke, David Berron, Benjamin Becker, Nirnath Sah, Galit Benoni, Emma Janke, Susan T Lubejko, Nigel H Greig, Julie A Mattison,[...]. Cell Metab 2016
8
Irisin a Novel Metabolic Biomarker: Present Knowledge and Future Directions.
Ilse Yessabel Martinez Munoz, Eneida Del Socorro Camarillo Romero, Jose de Jesus Garduno Garcia. Int J Endocrinol 2018
Ilse Yessabel Martinez Munoz, Eneida Del Socorro Camarillo Romero, Jose de Jesus Garduno Garcia. Int J Endocrinol 2018
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.