A citation-based method for searching scientific literature

Daniel Wacker, Raymond C Stevens, Bryan L Roth. Cell 2017
Times Cited: 266







List of co-cited articles
792 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Trends in GPCR drug discovery: new agents, targets and indications.
Alexander S Hauser, Misty M Attwood, Mathias Rask-Andersen, Helgi B Schiöth, David E Gloriam. Nat Rev Drug Discov 2017
980
27


The Molecular Basis of G Protein-Coupled Receptor Activation.
William I Weis, Brian K Kobilka. Annu Rev Biochem 2018
357
13

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints.
Robert Fredriksson, Malin C Lagerström, Lars-Gustav Lundin, Helgi B Schiöth. Mol Pharmacol 2003
11

Structure and dynamics of GPCR signaling complexes.
Daniel Hilger, Matthieu Masureel, Brian K Kobilka. Nat Struct Mol Biol 2018
341
10

Biased signalling: from simple switches to allosteric microprocessors.
Jeffrey S Smith, Robert J Lefkowitz, Sudarshan Rajagopal. Nat Rev Drug Discov 2018
309
9

Mechanisms of signalling and biased agonism in G protein-coupled receptors.
Denise Wootten, Arthur Christopoulos, Maria Marti-Solano, M Madan Babu, Patrick M Sexton. Nat Rev Mol Cell Biol 2018
237
9

A comprehensive map of molecular drug targets.
Rita Santos, Oleg Ursu, Anna Gaulton, A Patrícia Bento, Ramesh S Donadi, Cristian G Bologa, Anneli Karlsson, Bissan Al-Lazikani, Anne Hersey, Tudor I Oprea,[...]. Nat Rev Drug Discov 2017
879
9

Impact of GPCR Structures on Drug Discovery.
Miles Congreve, Chris de Graaf, Nigel A Swain, Christopher G Tate. Cell 2020
85
10

Structural diversity of G protein-coupled receptors and significance for drug discovery.
Malin C Lagerström, Helgi B Schiöth. Nat Rev Drug Discov 2008
989
8

Structure of the µ-opioid receptor-Gi protein complex.
Antoine Koehl, Hongli Hu, Shoji Maeda, Yan Zhang, Qianhui Qu, Joseph M Paggi, Naomi R Latorraca, Daniel Hilger, Roger Dawson, Hugues Matile,[...]. Nature 2018
301
8

Pharmacogenomics of GPCR Drug Targets.
Alexander S Hauser, Sreenivas Chavali, Ikuo Masuho, Leonie J Jahn, Kirill A Martemyanov, David E Gloriam, M Madan Babu. Cell 2018
268
8

Molecular signatures of G-protein-coupled receptors.
A J Venkatakrishnan, Xavier Deupi, Guillaume Lebon, Christopher G Tate, Gebhard F Schertler, M Madan Babu. Nature 2013
956
8

Ultra-large library docking for discovering new chemotypes.
Jiankun Lyu, Sheng Wang, Trent E Balius, Isha Singh, Anat Levit, Yurii S Moroz, Matthew J O'Meara, Tao Che, Enkhjargal Algaa, Kateryna Tolmachova,[...]. Nature 2019
266
7

Functional selectivity and classical concepts of quantitative pharmacology.
Jonathan D Urban, William P Clarke, Mark von Zastrow, David E Nichols, Brian Kobilka, Harel Weinstein, Jonathan A Javitch, Bryan L Roth, Arthur Christopoulos, Patrick M Sexton,[...]. J Pharmacol Exp Ther 2007
812
7

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling.
Aashish Manglik, Tae Hun Kim, Matthieu Masureel, Christian Altenbach, Zhongyu Yang, Daniel Hilger, Michael T Lerch, Tong Sun Kobilka, Foon Sun Thian, Wayne L Hubbell,[...]. Cell 2015
387
7

Advances in therapeutic peptides targeting G protein-coupled receptors.
Anthony P Davenport, Conor C G Scully, Chris de Graaf, Alastair J H Brown, Janet J Maguire. Nat Rev Drug Discov 2020
63
11

GPCR Signaling Regulation: The Role of GRKs and Arrestins.
Vsevolod V Gurevich, Eugenia V Gurevich. Front Pharmacol 2019
169
6

The role of kinetic context in apparent biased agonism at GPCRs.
Carmen Klein Herenbrink, David A Sykes, Prashant Donthamsetti, Meritxell Canals, Thomas Coudrat, Jeremy Shonberg, Peter J Scammells, Ben Capuano, Patrick M Sexton, Steven J Charlton,[...]. Nat Commun 2016
208
6

Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone.
Sheng Wang, Tao Che, Anat Levit, Brian K Shoichet, Daniel Wacker, Bryan L Roth. Nature 2018
203
6

D4 dopamine receptor high-resolution structures enable the discovery of selective agonists.
Sheng Wang, Daniel Wacker, Anat Levit, Tao Che, Robin M Betz, John D McCorvy, A J Venkatakrishnan, Xi-Ping Huang, Ron O Dror, Brian K Shoichet,[...]. Science 2017
111
6

Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Andrew C Kruse, Aaron M Ring, Aashish Manglik, Jianxin Hu, Kelly Hu, Katrin Eitel, Harald Hübner, Els Pardon, Celine Valant, Patrick M Sexton,[...]. Nature 2013
600
6

Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex.
Kaavya Krishna Kumar, Moran Shalev-Benami, Michael J Robertson, Hongli Hu, Samuel D Banister, Scott A Hollingsworth, Naomi R Latorraca, Hideaki E Kato, Daniel Hilger, Shoji Maeda,[...]. Cell 2019
186
6

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors.
Stephen P H Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding,[...]. Br J Pharmacol 2019
486
6

Signalling bias in new drug discovery: detection, quantification and therapeutic impact.
Terry Kenakin, Arthur Christopoulos. Nat Rev Drug Discov 2013
525
6

Transduction of receptor signals by beta-arrestins.
Robert J Lefkowitz, Sudha K Shenoy. Science 2005
6

Biased Receptor Signaling in Drug Discovery.
Terry Kenakin. Pharmacol Rev 2019
109
6

Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
X Edward Zhou, Yuanzheng He, Parker W de Waal, Xiang Gao, Yanyong Kang, Ned Van Eps, Yanting Yin, Kuntal Pal, Devrishi Goswami, Thomas A White,[...]. Cell 2017
219
6

Seven-transmembrane receptors.
Kristen L Pierce, Richard T Premont, Robert J Lefkowitz. Nat Rev Mol Cell Biol 2002
6

New Binding Sites, New Opportunities for GPCR Drug Discovery.
H C Stephen Chan, Yi Li, Thamani Dahoun, Horst Vogel, Shuguang Yuan. Trends Biochem Sci 2019
65
9

Anatomical profiling of G protein-coupled receptor expression.
Jean B Regard, Isaac T Sato, Shaun R Coughlin. Cell 2008
430
5

Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist.
Ellen Y T Chien, Wei Liu, Qiang Zhao, Vsevolod Katritch, Gye Won Han, Michael A Hanson, Lei Shi, Amy Hauck Newman, Jonathan A Javitch, Vadim Cherezov,[...]. Science 2010
866
5

The physiology, signaling, and pharmacology of dopamine receptors.
Jean-Martin Beaulieu, Raul R Gainetdinov. Pharmacol Rev 2011
5

Regulation, Signaling, and Physiological Functions of G-Proteins.
Viktoriya Syrovatkina, Kamela O Alegre, Raja Dey, Xin-Yun Huang. J Mol Biol 2016
153
5

Illuminating G-Protein-Coupling Selectivity of GPCRs.
Asuka Inoue, Francesco Raimondi, Francois Marie Ngako Kadji, Gurdeep Singh, Takayuki Kishi, Akiharu Uwamizu, Yuki Ono, Yuji Shinjo, Satoru Ishida, Nadia Arang,[...]. Cell 2019
164
5

Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go.
Javier García-Nafría, Rony Nehmé, Patricia C Edwards, Christopher G Tate. Nature 2018
124
5

Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes.
Shoji Maeda, Qianhui Qu, Michael J Robertson, Georgios Skiniotis, Brian K Kobilka. Science 2019
121
5

Heterotrimeric G-proteins: a short history.
Graeme Milligan, Evi Kostenis. Br J Pharmacol 2006
254
5

G-protein-coupled receptors at a glance.
Wesley K Kroeze, Douglas J Sheffler, Bryan L Roth. J Cell Sci 2003
212
5

Morphine side effects in beta-arrestin 2 knockout mice.
Kirsten M Raehal, Julia K L Walker, Laura M Bohn. J Pharmacol Exp Ther 2005
389
5

Morphine-induced respiratory depression is independent of β-arrestin2 signalling.
Andrea Kliewer, Alexander Gillis, Rob Hill, Frank Schmiedel, Chris Bailey, Eamonn Kelly, Graeme Henderson, Macdonald J Christie, Stefan Schulz. Br J Pharmacol 2020
96
5

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome.
Wesley K Kroeze, Maria F Sassano, Xi-Ping Huang, Katherine Lansu, John D McCorvy, Patrick M Giguère, Noah Sciaky, Bryan L Roth. Nat Struct Mol Biol 2015
289
5

PHENIX: a comprehensive Python-based system for macromolecular structure solution.
Paul D Adams, Pavel V Afonine, Gábor Bunkóczi, Vincent B Chen, Ian W Davis, Nathaniel Echols, Jeffrey J Headd, Li-Wei Hung, Gary J Kapral, Ralf W Grosse-Kunstleve,[...]. Acta Crystallogr D Biol Crystallogr 2010
5

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Yanyong Kang, X Edward Zhou, Xiang Gao, Yuanzheng He, Wei Liu, Andrii Ishchenko, Anton Barty, Thomas A White, Oleksandr Yefanov, Gye Won Han,[...]. Nature 2015
475
5

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Tao Che, Susruta Majumdar, Saheem A Zaidi, Pauline Ondachi, John D McCorvy, Sheng Wang, Philip D Mosier, Rajendra Uprety, Eyal Vardy, Brian E Krumm,[...]. Cell 2018
200
5

Structural insights into µ-opioid receptor activation.
Weijiao Huang, Aashish Manglik, A J Venkatakrishnan, Toon Laeremans, Evan N Feinberg, Adrian L Sanborn, Hideaki E Kato, Kathryn E Livingston, Thor S Thorsen, Ralf C Kling,[...]. Nature 2015
516
5

Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Søren G F Rasmussen, Brian T DeVree, Yaozhong Zou, Andrew C Kruse, Ka Young Chung, Tong Sun Kobilka, Foon Sun Thian, Pil Seok Chae, Els Pardon, Diane Calinski,[...]. Nature 2011
5

The structure and function of G-protein-coupled receptors.
Daniel M Rosenbaum, Søren G F Rasmussen, Brian K Kobilka. Nature 2009
5

Structural features for functional selectivity at serotonin receptors.
Daniel Wacker, Chong Wang, Vsevolod Katritch, Gye Won Han, Xi-Ping Huang, Eyal Vardy, John D McCorvy, Yi Jiang, Meihua Chu, Fai Yiu Siu,[...]. Science 2013
462
5

Structure of the neurotensin receptor 1 in complex with β-arrestin 1.
Weijiao Huang, Matthieu Masureel, Qianhui Qu, John Janetzko, Asuka Inoue, Hideaki E Kato, Michael J Robertson, Khanh C Nguyen, Jeffrey S Glenn, Georgios Skiniotis,[...]. Nature 2020
115
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.