A citation-based method for searching scientific literature

Shane M Harding, Joseph L Benci, Jerome Irianto, Dennis E Discher, Andy J Minn, Roger A Greenberg. Nature 2017
Times Cited: 684







List of co-cited articles
1214 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
732
65

Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli, Jiajun Zhu, Payel Sen, Kirk J Wangensteen, Johayra Simithy, Yemin Lan, Yanping Lin, Zhuo Zhou,[...]. Nature 2017
552
29

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.
Selene Glück, Baptiste Guey, Muhammet Fatih Gulen, Katharina Wolter, Tae-Won Kang, Niklas Arndt Schmacke, Anne Bridgeman, Jan Rehwinkel, Lars Zender, Andrea Ablasser. Nat Cell Biol 2017
486
28

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
27

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
Liufu Deng, Hua Liang, Meng Xu, Xuanming Yang, Byron Burnette, Ainhoa Arina, Xiao-Dong Li, Helena Mauceri, Michael Beckett, Thomas Darga,[...]. Immunity 2014
23

cGAS is essential for cellular senescence.
Hui Yang, Hanze Wang, Junyao Ren, Qi Chen, Zhijian J Chen. Proc Natl Acad Sci U S A 2017
452
21

Chromosomal instability drives metastasis through a cytosolic DNA response.
Samuel F Bakhoum, Bryan Ngo, Ashley M Laughney, Julie-Ann Cavallo, Charles J Murphy, Peter Ly, Pragya Shah, Roshan K Sriram, Thomas B K Watkins, Neil K Taunk,[...]. Nature 2018
587
20

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Haipeng Liu, Haiping Zhang, Xiangyang Wu, Dapeng Ma, Juehui Wu, Lin Wang, Yan Jiang, Yiyan Fei, Chenggang Zhu, Rong Tan,[...]. Nature 2018
270
19

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
18

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity.
Claire Vanpouille-Box, Amandine Alard, Molykutty J Aryankalayil, Yasmeen Sarfraz, Julie M Diamond, Robert J Schneider, Giorgio Inghirami, C Norman Coleman, Silvia C Formenti, Sandra Demaria. Nat Commun 2017
842
18

The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death.
Christian Zierhut, Norihiro Yamaguchi, Maria Paredes, Ji-Dung Luo, Thomas Carroll, Hironori Funabiki. Cell 2019
177
17


cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung. Nature 2013
854
16


STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.
Seng-Ryong Woo, Mercedes B Fuertes, Leticia Corrales, Stefani Spranger, Michael J Furdyna, Michael Y K Leung, Ryan Duggan, Ying Wang, Glen N Barber, Katherine A Fitzgerald,[...]. Immunity 2014
895
16

Catastrophic nuclear envelope collapse in cancer cell micronuclei.
Emily M Hatch, Andrew H Fischer, Thomas J Deerinck, Martin W Hetzer. Cell 2013
394
15

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.
Qi Chen, Lijun Sun, Zhijian J Chen. Nat Immunol 2016
892
15

Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death.
Hui Jiang, Xiaoyu Xue, Swarupa Panda, Ajinkya Kawale, Richard M Hooy, Fengshan Liang, Jungsan Sohn, Patrick Sung, Nelson O Gekara. EMBO J 2019
107
14

Structural mechanism of cytosolic DNA sensing by cGAS.
Filiz Civril, Tobias Deimling, Carina C de Oliveira Mann, Andrea Ablasser, Manuela Moldt, Gregor Witte, Veit Hornung, Karl-Peter Hopfner. Nature 2013
423
14

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.
Xiang Gui, Hui Yang, Tuo Li, Xiaojun Tan, Peiqing Shi, Minghao Li, Fenghe Du, Zhijian J Chen. Nature 2019
375
14

Molecular mechanisms and cellular functions of cGAS-STING signalling.
Karl-Peter Hopfner, Veit Hornung. Nat Rev Mol Cell Biol 2020
337
13


Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.
Gillian Dunphy, Sinéad M Flannery, Jessica F Almine, Dympna J Connolly, Christina Paulus, Kasper L Jønsson, Martin R Jakobsen, Michael M Nevels, Andrew G Bowie, Leonie Unterholzner. Mol Cell 2018
256
13

The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells.
Samantha S W Ho, Wendy Y L Zhang, Nikki Yi Jie Tan, Muznah Khatoo, Manuel A Suter, Shubhita Tripathi, Florence S G Cheung, Weng Khong Lim, Puay Hoon Tan, Joanne Ngeow,[...]. Immunity 2016
128
13

ER-directed TREX1 limits cGAS activation at micronuclei.
Lisa Mohr, Eléonore Toufektchan, Patrick von Morgen, Kevan Chu, Aakanksha Kapoor, John Maciejowski. Mol Cell 2021
47
25

Trex1 prevents cell-intrinsic initiation of autoimmunity.
Daniel B Stetson, Joan S Ko, Thierry Heidmann, Ruslan Medzhitov. Cell 2008
865
12

Tight nuclear tethering of cGAS is essential for preventing autoreactivity.
Hannah E Volkman, Stephanie Cambier, Elizabeth E Gray, Daniel B Stetson. Elife 2019
114
11

DNA breaks and chromosome pulverization from errors in mitosis.
Karen Crasta, Neil J Ganem, Regina Dagher, Alexandra B Lantermann, Elena V Ivanova, Yunfeng Pan, Luigi Nezi, Alexei Protopopov, Dipanjan Chowdhury, David Pellman. Nature 2012
782
11

Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.
Xin Li, Chang Shu, Guanghui Yi, Catherine T Chaton, Catherine L Shelton, Jiasheng Diao, Xiaobing Zuo, C Cheng Kao, Andrew B Herr, Pingwei Li. Immunity 2013
315
11

DNA sensing by the cGAS-STING pathway in health and disease.
Mona Motwani, Scott Pesiridis, Katherine A Fitzgerald. Nat Rev Genet 2019
412
11

Mitochondrial DNA stress primes the antiviral innate immune response.
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
858
11

Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer.
Eileen E Parkes, Steven M Walker, Laura E Taggart, Nuala McCabe, Laura A Knight, Richard Wilkinson, Karen D McCloskey, Niamh E Buckley, Kienan I Savage, Manuel Salto-Tellez,[...]. J Natl Cancer Inst 2016
237
11

DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells.
Hiro Sato, Atsuko Niimi, Takaaki Yasuhara, Tiara Bunga Mayang Permata, Yoshihiko Hagiwara, Mayu Isono, Endang Nuryadi, Ryota Sekine, Takahiro Oike, Sangeeta Kakoti,[...]. Nat Commun 2017
322
11

The Cytosolic DNA-Sensing cGAS-STING Pathway in Cancer.
John Kwon, Samuel F Bakhoum. Cancer Discov 2020
247
11

DNA-PK is a DNA sensor for IRF-3-dependent innate immunity.
Brian J Ferguson, Daniel S Mansur, Nicholas E Peters, Hongwei Ren, Geoffrey L Smith. Elife 2012
265
11

DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity.
Anetta Härtlova, Saskia F Erttmann, Faizal Am Raffi, Anja M Schmalz, Ulrike Resch, Sharath Anugula, Stefan Lienenklaus, Lisa M Nilsson, Andrea Kröger, Jonas A Nilsson,[...]. Immunity 2015
431
11




The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop.
Xu Zhang, Jiaxi Wu, Fenghe Du, Hui Xu, Lijun Sun, Zhe Chen, Chad A Brautigam, Xuewu Zhang, Zhijian J Chen. Cell Rep 2014
251
10

Phosphorylation and chromatin tethering prevent cGAS activation during mitosis.
Tuo Li, Tuozhi Huang, Mingjian Du, Xiang Chen, Fenghe Du, Junyao Ren, Zhijian J Chen. Science 2021
61
16

SAMHD1 acts at stalled replication forks to prevent interferon induction.
Flavie Coquel, Maria-Joao Silva, Hervé Técher, Karina Zadorozhny, Sushma Sharma, Jadwiga Nieminuszczy, Clément Mettling, Elodie Dardillac, Antoine Barthe, Anne-Lyne Schmitz,[...]. Nature 2018
198
10

Activation of STING requires palmitoylation at the Golgi.
Kojiro Mukai, Hiroyasu Konno, Tatsuya Akiba, Takefumi Uemura, Satoshi Waguri, Toshihide Kobayashi, Glen N Barber, Hiroyuki Arai, Tomohiko Taguchi. Nat Commun 2016
248
10

ATR inhibition potentiates ionizing radiation-induced interferon response via cytosolic nucleic acid-sensing pathways.
Xu Feng, Anthony Tubbs, Chunchao Zhang, Mengfan Tang, Sriram Sridharan, Chao Wang, Dadi Jiang, Dan Su, Huimin Zhang, Zhen Chen,[...]. EMBO J 2020
48
20

PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer.
Constantia Pantelidou, Olmo Sonzogni, Mateus De Oliveria Taveira, Anita K Mehta, Aditi Kothari, Dan Wang, Tanvi Visal, Michelle K Li, Jocelin Pinto, Jessica A Castrillon,[...]. Cancer Discov 2019
263
10

Structural basis of STING binding with and phosphorylation by TBK1.
Conggang Zhang, Guijun Shang, Xiang Gui, Xuewu Zhang, Xiao-Chen Bai, Zhijian J Chen. Nature 2019
272
10

Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann,[...]. Cell 2013
573
10

Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.
Xu Zhang, Heping Shi, Jiaxi Wu, Xuewu Zhang, Lijun Sun, Chuo Chen, Zhijian J Chen. Mol Cell 2013
585
10

The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.
Matteo Gentili, Xavier Lahaye, Francesca Nadalin, Guilherme P F Nader, Emilia Puig Lombardi, Solène Herve, Nilushi S De Silva, Derek C Rookhuizen, Elina Zueva, Christel Goudot,[...]. Cell Rep 2019
100
9

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
667
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.