A citation-based method for searching scientific literature

Clifford J Bailey. Diabetologia 2017
Times Cited: 243







List of co-cited articles
837 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The mechanisms of action of metformin.
Graham Rena, D Grahame Hardie, Ewan R Pearson. Diabetologia 2017
675
25

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Anila K Madiraju, Derek M Erion, Yasmeen Rahimi, Xian-Man Zhang, Demetrios T Braddock, Ronald A Albright, Brett J Prigaro, John L Wood, Sanjay Bhanot, Michael J MacDonald,[...]. Nature 2014
672
15

Role of AMP-activated protein kinase in mechanism of metformin action.
G Zhou, R Myers, Y Li, Y Chen, X Shen, J Fenyk-Melody, M Wu, J Ventre, T Doebber, N Fujii,[...]. J Clin Invest 2001
13

Clinical pharmacokinetics of metformin.
Garry G Graham, Jeroen Punt, Manit Arora, Richard O Day, Matthew P Doogue, Janna K Duong, Timothy J Furlong, Jerry R Greenfield, Louise C Greenup, Carl M Kirkpatrick,[...]. Clin Pharmacokinet 2011
605
13

Metformin Treatment Was Associated with Decreased Mortality in COVID-19 Patients with Diabetes in a Retrospective Analysis.
Pan Luo, Lin Qiu, Yi Liu, Xiu-Lan Liu, Jian-Ling Zheng, Hui-Ying Xue, Wen-Hua Liu, Dong Liu, Juan Li. Am J Trop Med Hyg 2020
111
12

Metformin: clinical use in type 2 diabetes.
Elizabeth Sanchez-Rangel, Silvio E Inzucchi. Diabetologia 2017
126
11

Metformin as a Tool to Target Aging.
Nir Barzilai, Jill P Crandall, Stephen B Kritchevsky, Mark A Espeland. Cell Metab 2016
426
10


Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status.
Amy R Cameron, Vicky L Morrison, Daniel Levin, Mohapradeep Mohan, Calum Forteath, Craig Beall, Alison D McNeilly, David J K Balfour, Terhi Savinko, Aaron K F Wong,[...]. Circ Res 2016
264
10

Metformin and reduced risk of cancer in diabetic patients.
Josie M M Evans, Louise A Donnelly, Alistair M Emslie-Smith, Dario R Alessi, Andrew D Morris. BMJ 2005
9

Cellular and molecular mechanisms of metformin: an overview.
Benoit Viollet, Bruno Guigas, Nieves Sanz Garcia, Jocelyne Leclerc, Marc Foretz, Fabrizio Andreelli. Clin Sci (Lond) 2012
964
9

Metformin: from mechanisms of action to therapies.
Marc Foretz, Bruno Guigas, Luc Bertrand, Michael Pollak, Benoit Viollet. Cell Metab 2014
611
9

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.
M Y El-Mir, V Nogueira, E Fontaine, N Avéret, M Rigoulet, X Leverve. J Biol Chem 2000
933
9

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.
Russell A Miller, Qingwei Chu, Jianxin Xie, Marc Foretz, Benoit Viollet, Morris J Birnbaum. Nature 2013
502
9

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria.
Hannah R Bridges, Andrew J Y Jones, Michael N Pollak, Judy Hirst. Biochem J 2014
364
9

GDF15 mediates the effects of metformin on body weight and energy balance.
Anthony P Coll, Michael Chen, Pranali Taskar, Debra Rimmington, Satish Patel, John A Tadross, Irene Cimino, Ming Yang, Paul Welsh, Samuel Virtue,[...]. Nature 2020
124
9

Metformin and the gastrointestinal tract.
Laura J McCreight, Clifford J Bailey, Ewan R Pearson. Diabetologia 2016
276
9

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells.
Mahvash Zakikhani, Ryan Dowling, I George Fantus, Nahum Sonenberg, Michael Pollak. Cancer Res 2006
806
8

The beneficial effects of metformin on cancer prevention and therapy: a comprehensive review of recent advances.
Pouya Saraei, Ilia Asadi, Muhammad Azam Kakar, Nasroallah Moradi-Kor. Cancer Manag Res 2019
96
8

Clinical pharmacokinetics of metformin.
A J Scheen. Clin Pharmacokinet 1996
384
8

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Marc Foretz, Sophie Hébrard, Jocelyne Leclerc, Elham Zarrinpashneh, Maud Soty, Gilles Mithieux, Kei Sakamoto, Fabrizio Andreelli, Benoit Viollet. J Clin Invest 2010
810
8



Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.
Yan Shu, Steven A Sheardown, Chaline Brown, Ryan P Owen, Shuzhong Zhang, Richard A Castro, Alexandra G Ianculescu, Lin Yue, Joan C Lo, Esteban G Burchard,[...]. J Clin Invest 2007
603
8

Metformin in COVID-19: A possible role beyond diabetes.
Swati Sharma, Avik Ray, Balakrishnan Sadasivam. Diabetes Res Clin Pract 2020
83
9

Mechanism of Metformin: A Tale of Two Sites.
Ruisheng Song. Diabetes Care 2016
67
11

Repurposing metformin for cancer treatment: current clinical studies.
Young Kwang Chae, Ayush Arya, Mary-Kate Malecek, Daniel Sanghoon Shin, Benedito Carneiro, Sunandana Chandra, Jason Kaplan, Aparna Kalyan, Jessica K Altman, Leonidas Platanias,[...]. Oncotarget 2016
175
7

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug.
Hao Wu, Eduardo Esteve, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås-Holm, Marcus Ståhlman, Lisa M Olsson, Matteo Serino, Mercè Planas-Fèlix,[...]. Nat Med 2017
577
7

Repositioning metformin for cancer prevention and treatment.
Brendan J Quinn, Hiroshi Kitagawa, Regan M Memmott, Joell J Gills, Phillip A Dennis. Trends Endocrinol Metab 2013
193
7

Metformin action: concentrations matter.
Ling He, Fredric E Wondisford. Cell Metab 2015
219
7


Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Adem Kalender, Anand Selvaraj, So Young Kim, Pawan Gulati, Sophie Brûlé, Benoit Viollet, Bruce E Kemp, Nabeel Bardeesy, Patrick Dennis, John J Schlager,[...]. Cell Metab 2010
574
7

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus.
Marc Foretz, Bruno Guigas, Benoit Viollet. Nat Rev Endocrinol 2019
135
7

Metformin--mode of action and clinical implications for diabetes and cancer.
Ida Pernicova, Márta Korbonits. Nat Rev Endocrinol 2014
615
6


Metformin pathways: pharmacokinetics and pharmacodynamics.
Li Gong, Srijib Goswami, Kathleen M Giacomini, Russ B Altman, Teri E Klein. Pharmacogenet Genomics 2012
232
6

Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo.
Anila K Madiraju, Yang Qiu, Rachel J Perry, Yasmeen Rahimi, Xian-Man Zhang, Dongyan Zhang, João-Paulo G Camporez, Gary W Cline, Gina M Butrico, Bruce E Kemp,[...]. Nat Med 2018
94
6

The Primary Glucose-Lowering Effect of Metformin Resides in the Gut, Not the Circulation: Results From Short-term Pharmacokinetic and 12-Week Dose-Ranging Studies.
John B Buse, Ralph A DeFronzo, Julio Rosenstock, Terri Kim, Colleen Burns, Sharon Skare, Alain Baron, Mark Fineman. Diabetes Care 2016
171
6

Is Metformin a Perfect Drug? Updates in Pharmacokinetics and Pharmacodynamics.
Magdalena Markowicz-Piasecka, Kristiina M Huttunen, Lukasz Mateusiak, Elzbieta Mikiciuk-Olasik, Joanna Sikora. Curr Pharm Des 2017
38
15

10-year follow-up of intensive glucose control in type 2 diabetes.
Rury R Holman, Sanjoy K Paul, M Angelyn Bethel, David R Matthews, H Andrew W Neil. N Engl J Med 2008
6


Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle,[...]. N Engl J Med 2015
6

In Vivo Imaging of Human 11C-Metformin in Peripheral Organs: Dosimetry, Biodistribution, and Kinetic Analyses.
Lars C Gormsen, Elias Immanuel Sundelin, Jonas Brorson Jensen, Mikkel Holm Vendelbo, Steen Jakobsen, Ole Lajord Munk, Mette Marie Hougaard Christensen, Kim Brøsen, Jørgen Frøkiær, Niels Jessen. J Nucl Med 2016
65
9

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.
Kristoffer Forslund, Falk Hildebrand, Trine Nielsen, Gwen Falony, Emmanuelle Le Chatelier, Shinichi Sunagawa, Edi Prifti, Sara Vieira-Silva, Valborg Gudmundsdottir, Helle K Pedersen,[...]. Nature 2015
909
6

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis.
William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, Gr Scott Budigner,[...]. Elife 2014
574
6

Benefits of Metformin in Attenuating the Hallmarks of Aging.
Ameya S Kulkarni, Sriram Gubbi, Nir Barzilai. Cell Metab 2020
92
6

2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
John B Buse, Deborah J Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A D'Alessio, Melanie J Davies. Diabetes Care 2020
358
6

Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes.
Xu Cheng, Ye-Mao Liu, Haomiao Li, Xin Zhang, Fang Lei, Juan-Juan Qin, Ze Chen, Ke-Qiong Deng, Lijin Lin, Ming-Ming Chen,[...]. Cell Metab 2020
56
10


Cellular and Molecular Mechanisms of Metformin Action.
Traci E LaMoia, Gerald I Shulman. Endocr Rev 2021
31
19


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.