Yin Cai, Vidya Kandula, Ramoji Kosuru, Xiaodong Ye, Michael G Irwin, Zhengyuan Xia. Cell Cycle 2017
Times Cited: 24
Times Cited: 24
Times Cited
Times Co-cited
Similarity
A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance.
Paula Martínez, Gonzalo Gómez-López, David G Pisano, Juana M Flores, Maria A Blasco. Aging Cell 2016
Paula Martínez, Gonzalo Gómez-López, David G Pisano, Juana M Flores, Maria A Blasco. Aging Cell 2016
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RAP1 protects from obesity through its extratelomeric role regulating gene expression.
Paula Martínez, Gonzalo Gómez-López, Fernando García, Evi Mercken, Sarah Mitchell, Juana M Flores, Rafael de Cabo, Maria A Blasco. Cell Rep 2013
Paula Martínez, Gonzalo Gómez-López, Fernando García, Evi Mercken, Sarah Mitchell, Juana M Flores, Rafael de Cabo, Maria A Blasco. Cell Rep 2013
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Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal.
Agnel Sfeir, Shaheen Kabir, Megan van Overbeek, Giulia B Celli, Titia de Lange. Science 2010
Agnel Sfeir, Shaheen Kabir, Megan van Overbeek, Giulia B Celli, Titia de Lange. Science 2010
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Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression.
Hsiangling Teo, Sourav Ghosh, Hendrik Luesch, Arkasubhra Ghosh, Ee Tsin Wong, Najib Malik, Anthony Orth, Paul de Jesus, Anthony S Perry, Jeffrey D Oliver,[...]. Nat Cell Biol 2010
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Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
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Identification of human Rap1: implications for telomere evolution.
B Li, S Oestreich, T de Lange. Cell 2000
B Li, S Oestreich, T de Lange. Cell 2000
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Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites.
Paula Martinez, Maria Thanasoula, Ana R Carlos, Gonzalo Gómez-López, Agueda M Tejera, Stefan Schoeftner, Orlando Dominguez, David G Pisano, Madalena Tarsounas, Maria A Blasco. Nat Cell Biol 2010
Paula Martinez, Maria Thanasoula, Ana R Carlos, Gonzalo Gómez-López, Agueda M Tejera, Stefan Schoeftner, Orlando Dominguez, David G Pisano, Madalena Tarsounas, Maria A Blasco. Nat Cell Biol 2010
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Cancer. Cancer and telomeres--an ALTernative to telomerase.
Jerry W Shay, Roger R Reddel, Woodring E Wright. Science 2012
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Ras and Rap1: A tale of two GTPases.
Seema Shah, Ethan J Brock, Kyungmin Ji, Raymond R Mattingly. Semin Cancer Biol 2019
Seema Shah, Ethan J Brock, Kyungmin Ji, Raymond R Mattingly. Semin Cancer Biol 2019
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Rap1 induces cytokine production in pro-inflammatory macrophages through NFκB signaling and is highly expressed in human atherosclerotic lesions.
Yin Cai, Galina K Sukhova, Hoi Kin Wong, Aimin Xu, Vinay Tergaonkar, Paul M Vanhoutte, Eva Hoi Ching Tang. Cell Cycle 2015
Yin Cai, Galina K Sukhova, Hoi Kin Wong, Aimin Xu, Vinay Tergaonkar, Paul M Vanhoutte, Eva Hoi Ching Tang. Cell Cycle 2015
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Telomeres in cancer: tumour suppression and genome instability.
John Maciejowski, Titia de Lange. Nat Rev Mol Cell Biol 2017
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Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription.
D E Gottschling, O M Aparicio, B L Billington, V A Zakian. Cell 1990
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Telomeres and telomerase: three decades of progress.
Jerry W Shay, Woodring E Wright. Nat Rev Genet 2019
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Mammalian telomeres and their partnership with lamins.
Romina Burla, Mattia La Torre, Isabella Saggio. Nucleus 2016
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Telomere dysfunction induces metabolic and mitochondrial compromise.
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Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes.
Bruce Neal, Vlado Perkovic, Kenneth W Mahaffey, Dick de Zeeuw, Greg Fulcher, Ngozi Erondu, Wayne Shaw, Gordon Law, Mehul Desai, David R Matthews. N Engl J Med 2017
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Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle,[...]. N Engl J Med 2015
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Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
Sandy Chang, Asha S Multani, Noelia G Cabrera, Maria L Naylor, Purnima Laud, David Lombard, Sen Pathak, Leonard Guarente, Ronald A DePinho. Nat Genet 2004
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Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.
Dirk Hockemeyer, Jan-Peter Daniels, Hiroyuki Takai, Titia de Lange. Cell 2006
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Longevity, stress response, and cancer in aging telomerase-deficient mice.
K L Rudolph, S Chang, H W Lee, M Blasco, G J Gottlieb, C Greider, R A DePinho. Cell 1999
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Essential role of mouse telomerase in highly proliferative organs.
H W Lee, M A Blasco, G J Gottlieb, J W Horner, C W Greider, R A DePinho. Nature 1998
H W Lee, M A Blasco, G J Gottlieb, J W Horner, C W Greider, R A DePinho. Nature 1998
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TRF1 is a stem cell marker and is essential for the generation of induced pluripotent stem cells.
Ralph P Schneider, Ianire Garrobo, Miguel Foronda, Jose A Palacios, Rosa M Marión, Ignacio Flores, Sagrario Ortega, Maria A Blasco. Nat Commun 2013
Ralph P Schneider, Ianire Garrobo, Miguel Foronda, Jose A Palacios, Rosa M Marión, Ignacio Flores, Sagrario Ortega, Maria A Blasco. Nat Commun 2013
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Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
Maria Eriksson, W Ted Brown, Leslie B Gordon, Michael W Glynn, Joel Singer, Laura Scott, Michael R Erdos, Christiane M Robbins, Tracy Y Moses, Peter Berglund,[...]. Nature 2003
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Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery.
K L Rudolph, S Chang, M Millard, N Schreiber-Agus, R A DePinho. Science 2000
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Circulating miRNA Profiles Associated With Hyperglycemia in Patients With Type 1 Diabetes.
Eiichiro Satake, Marcus G Pezzolesi, Zaipul I Md Dom, Adam M Smiles, Monika A Niewczas, Andrzej S Krolewski. Diabetes 2018
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Rap1B promotes VEGF-induced endothelial permeability and is required for dynamic regulation of the endothelial barrier.
Sribalaji Lakshmikanthan, Magdalena Sobczak, Sergio Li Calzi, Lynn Shaw, Maria B Grant, Magdalena Chrzanowska-Wodnicka. J Cell Sci 2018
Sribalaji Lakshmikanthan, Magdalena Sobczak, Sergio Li Calzi, Lynn Shaw, Maria B Grant, Magdalena Chrzanowska-Wodnicka. J Cell Sci 2018
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Licochalcone F alleviates glucose tolerance and chronic inflammation in diet-induced obese mice through Akt and p38 MAPK.
Eun-Jung Bak, Kyung-Chul Choi, Sungil Jang, Gye-Hyeong Woo, Ho-Geun Yoon, Younghwa Na, Yun-Jung Yoo, Youngseok Lee, Yangsik Jeong, Jeong-Heon Cha. Clin Nutr 2016
Eun-Jung Bak, Kyung-Chul Choi, Sungil Jang, Gye-Hyeong Woo, Ho-Geun Yoon, Younghwa Na, Yun-Jung Yoo, Youngseok Lee, Yangsik Jeong, Jeong-Heon Cha. Clin Nutr 2016
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TAB3 involves in hepatic insulin resistance through activation of MAPK pathway.
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Global aetiology and epidemiology of type 2 diabetes mellitus and its complications.
Yan Zheng, Sylvia H Ley, Frank B Hu. Nat Rev Endocrinol 2018
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Role of Telomeric TRF2 in Orosphere Formation and CSC Phenotype Maintenance Through Efficient DNA Repair Pathway and its Correlation with Recurrence in OSCC.
Arka Saha, Souvick Roy, Madhabananda Kar, Shomereeta Roy, Shweta Thakur, SwatiShree Padhi, Yusuf Akhter, Birendranath Banerjee. Stem Cell Rev Rep 2018
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Removal of shelterin reveals the telomere end-protection problem.
Agnel Sfeir, Titia de Lange. Science 2012
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TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions.
Rekha Rai, Yong Chen, Ming Lei, Sandy Chang. Nat Commun 2016
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Taking apart Rap1: an adaptor protein with telomeric and non-telomeric functions.
Shaheen Kabir, Agnel Sfeir, Titia de Lange. Cell Cycle 2010
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A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis.
C W Greider, E H Blackburn. Nature 1989
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Deletion of Rap1 disrupts redox balance and impairs endothelium-dependent relaxations.
Kenneth H K Wong, Yin Cai, Fan Ying, Xinyi Chen, Paul M Vanhoutte, Eva H C Tang. J Mol Cell Cardiol 2018
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Rap1 affects the length and heterogeneity of human telomeres.
Bibo Li, Titia de Lange. Mol Biol Cell 2003
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A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends.
Nancy S Bae, Peter Baumann. Mol Cell 2007
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Mice lacking prostaglandin E receptor subtype 4 manifest disrupted lipid metabolism attributable to impaired triglyceride clearance.
Yin Cai, Fan Ying, Erfei Song, Yu Wang, Aimin Xu, Paul M Vanhoutte, Eva Hoi-Ching Tang. FASEB J 2015
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Replicating through telomeres: a means to an end.
Paula Martínez, Maria A Blasco. Trends Biochem Sci 2015
Paula Martínez, Maria A Blasco. Trends Biochem Sci 2015
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Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis.
Xing Zhang, Zunpeng Liu, Xiaoqian Liu, Si Wang, Yiyuan Zhang, Xiaojuan He, Shuhui Sun, Shuai Ma, Ng Shyh-Chang, Feng Liu,[...]. Protein Cell 2019
Xing Zhang, Zunpeng Liu, Xiaoqian Liu, Si Wang, Yiyuan Zhang, Xiaojuan He, Shuhui Sun, Shuai Ma, Ng Shyh-Chang, Feng Liu,[...]. Protein Cell 2019
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Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length.
L Sussel, D Shore. Proc Natl Acad Sci U S A 1991
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Human telomeric proteins occupy selective interstitial sites.
Dong Yang, Yuanyan Xiong, Hyeung Kim, Quanyuan He, Yumei Li, Rui Chen, Zhou Songyang. Cell Res 2011
Dong Yang, Yuanyan Xiong, Hyeung Kim, Quanyuan He, Yumei Li, Rui Chen, Zhou Songyang. Cell Res 2011
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Molecular mechanisms of activity and derepression of alternative lengthening of telomeres.
Hilda A Pickett, Roger R Reddel. Nat Struct Mol Biol 2015
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Noncanonical functions of telomerase: implications in telomerase-targeted cancer therapies.
Yinghui Li, Vinay Tergaonkar. Cancer Res 2014
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Alternative lengthening of telomeres and loss of ATRX are frequent events in pleomorphic and dedifferentiated liposarcomas.
Jen-Chieh Lee, Yung-Ming Jeng, Jau-Yu Liau, Jia-Huei Tsai, Hung-Han Hsu, Ching-Yao Yang. Mod Pathol 2015
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Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.
Jian Hu, Soyoon Sarah Hwang, Marc Liesa, Boyi Gan, Ergun Sahin, Mariela Jaskelioff, Zhihu Ding, Haoqiang Ying, Adam T Boutin, Hailei Zhang,[...]. Cell 2012
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The Many Faces of Rap1 GTPase.
Anna Jaśkiewicz, Beata Pająk, Arkadiusz Orzechowski. Int J Mol Sci 2018
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.