A citation-based method for searching scientific literature

Steven Wang, Alexandra M Pike, Stella S Lee, Margaret A Strong, Carla J Connelly, Carol W Greider. Nucleic Acids Res 2017
Times Cited: 19

List of co-cited articles
158 articles co-cited >1

Times Cited
  Times     Co-cited

BRD4 and Cancer: going beyond transcriptional regulation.
Benedetta Donati, Eugenia Lorenzini, Alessia Ciarrocchi. Mol Cancer 2018

BET bromodomain inhibition as a therapeutic strategy to target c-Myc.
Jake E Delmore, Ghayas C Issa, Madeleine E Lemieux, Peter B Rahl, Junwei Shi, Hannah M Jacobs, Efstathios Kastritis, Timothy Gilpatrick, Ronald M Paranal, Jun Qi,[...]. Cell 2011

Selective inhibition of BET bromodomains.
Panagis Filippakopoulos, Jun Qi, Sarah Picaud, Yao Shen, William B Smith, Oleg Fedorov, Elizabeth M Morse, Tracey Keates, Tyler T Hickman, Ildiko Felletar,[...]. Nature 2010

BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer.
Xiangyi Li, GuemHee Baek, Susmita G Ramanand, Adam Sharp, Yunpeng Gao, Wei Yuan, Jon Welti, Daniel N Rodrigues, David Dolling, Ines Figueiredo,[...]. Cell Rep 2018

The bromodomain protein Brd4 stimulates G1 gene transcription and promotes progression to S phase.
Kazuki Mochizuki, Akira Nishiyama, Moon Kyoo Jang, Anup Dey, Anu Ghosh, Tomohiko Tamura, Hiroko Natsume, Hongjie Yao, Keiko Ozato. J Biol Chem 2008

Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA.
Bo Huang, Xiao-Dong Yang, Ming-Ming Zhou, Keiko Ozato, Lin-Feng Chen. Mol Cell Biol 2009

Chromatin reader Brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining.
Andre Stanlie, Ashraf S Yousif, Hideo Akiyama, Tasuku Honjo, Nasim A Begum. Mol Cell 2014

Histone recognition and large-scale structural analysis of the human bromodomain family.
Panagis Filippakopoulos, Sarah Picaud, Maria Mangos, Tracy Keates, Jean-Philippe Lambert, Dalia Barsyte-Lovejoy, Ildiko Felletar, Rudolf Volkmer, Susanne Müller, Tony Pawson,[...]. Cell 2012

Structure and function of telomeres.
E H Blackburn. Nature 1991

RUNX2 expression in thyroid and breast cancer requires the cooperation of three non-redundant enhancers under the control of BRD4 and c-JUN.
Valentina Sancisi, Gloria Manzotti, Mila Gugnoni, Teresa Rossi, Greta Gandolfi, Giulia Gobbi, Federica Torricelli, Francesca Catellani, Italo Faria do Valle, Daniel Remondini,[...]. Nucleic Acids Res 2017

Selective inhibition of tumor oncogenes by disruption of super-enhancers.
Jakob Lovén, Heather A Hoke, Charles Y Lin, Ashley Lau, David A Orlando, Christopher R Vakoc, James E Bradner, Tong Ihn Lee, Richard A Young. Cell 2013

Bromodomain inhibitor OTX015 in patients with lymphoma or multiple myeloma: a dose-escalation, open-label, pharmacokinetic, phase 1 study.
Sandy Amorim, Anastasios Stathis, Mary Gleeson, Sunil Iyengar, Valeria Magarotto, Xavier Leleu, Franck Morschhauser, Lionel Karlin, Florence Broussais, Keyvan Rezai,[...]. Lancet Haematol 2016

Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study.
Céline Berthon, Emmanuel Raffoux, Xavier Thomas, Norbert Vey, Carlos Gomez-Roca, Karen Yee, David Christopher Taussig, Keyvan Rezai, Christophe Roumier, Patrice Herait,[...]. Lancet Haematol 2016

How shelterin protects mammalian telomeres.
Wilhelm Palm, Titia de Lange. Annu Rev Genet 2008

BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin.
Ballachanda N Devaiah, Chanelle Case-Borden, Anne Gegonne, Chih Hao Hsu, Qingrong Chen, Daoud Meerzaman, Anup Dey, Keiko Ozato, Dinah S Singer. Nat Struct Mol Biol 2016

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Mark A Dawson, Rab K Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel C Robson, Chun-wa Chung, Carsten Hopf, Mikhail M Savitski,[...]. Nature 2011

BRD4 facilitates replication stress-induced DNA damage response.
Jingwen Zhang, Austin M Dulak, Maureen M Hattersley, Brandon S Willis, Jenni Nikkilä, Anderson Wang, Alan Lau, Corinne Reimer, Michael Zinda, Stephen E Fawell,[...]. Oncogene 2018

Long-Range Chromatin Interactions Drive Mutant TERT Promoter Activation.
Semih Can Akıncılar, Ekta Khattar, Priscilla Li Shan Boon, Bilal Unal, Melissa Jane Fullwood, Vinay Tergaonkar. Cancer Discov 2016

High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML.
Yue Zhao, Qi Liu, Pankaj Acharya, Kristy R Stengel, Quanhu Sheng, Xiaofan Zhou, Hojoong Kwak, Melissa A Fischer, James E Bradner, Stephen A Strickland,[...]. Cell Rep 2016

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition.
A Dey, J Ellenberg, A Farina, A E Coleman, T Maruyama, S Sciortino, J Lippincott-Schwartz, K Ozato. Mol Cell Biol 2000

Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.
Denis Houzelstein, Simon L Bullock, Denise E Lynch, Elena F Grigorieva, Valerie A Wilson, Rosa S P Beddington. Mol Cell Biol 2002

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Johannes Zuber, Junwei Shi, Eric Wang, Amy R Rappaport, Harald Herrmann, Edward A Sison, Daniel Magoon, Jun Qi, Katharina Blatt, Mark Wunderlich,[...]. Nature 2011

A three-state model for the regulation of telomerase by TERRA and hnRNPA1.
Sophie Redon, Ivo Zemp, Joachim Lingner. Nucleic Acids Res 2013

Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins.
William W Lockwood, Kreshnik Zejnullahu, James E Bradner, Harold Varmus. Proc Natl Acad Sci U S A 2012

CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer.
Mark L McCleland, Kathryn Mesh, Edward Lorenzana, Vivek S Chopra, Ehud Segal, Colin Watanabe, Benjamin Haley, Oleg Mayba, Murat Yaylaoglu, Florian Gnad,[...]. J Clin Invest 2016

BET inhibition silences expression of MYCN and BCL2 and induces cytotoxicity in neuroblastoma tumor models.
Anastasia Wyce, Gopinath Ganji, Kimberly N Smitheman, Chun-Wa Chung, Susan Korenchuk, Yuchen Bai, Olena Barbash, BaoChau Le, Peter D Craggs, Michael T McCabe,[...]. PLoS One 2013

The BET Bromodomain Inhibitor OTX015 Affects Pathogenetic Pathways in Preclinical B-cell Tumor Models and Synergizes with Targeted Drugs.
Michela Boi, Eugenio Gaudio, Paola Bonetti, Ivo Kwee, Elena Bernasconi, Chiara Tarantelli, Andrea Rinaldi, Monica Testoni, Luciano Cascione, Maurilio Ponzoni,[...]. Clin Cancer Res 2015

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.
Simon J Hogg, Stephin J Vervoort, Sumit Deswal, Christopher J Ott, Jason Li, Leonie A Cluse, Paul A Beavis, Phillip K Darcy, Benjamin P Martin, Andrew Spencer,[...]. Cell Rep 2017

BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail.
Zhong-Yi Qin, Tao Wang, Siyuan Su, Li-Ting Shen, Guang-Xi Zhu, Qin Liu, Liang Zhang, Ke-Wei Liu, Yue Zhang, Zhi-Hua Zhou,[...]. Cancer Res 2019

Frequency of TERT promoter mutations in human cancers.
João Vinagre, Ana Almeida, Helena Pópulo, Rui Batista, Joana Lyra, Vasco Pinto, Ricardo Coelho, Ricardo Celestino, Hugo Prazeres, Luis Lima,[...]. Nat Commun 2013

Genome-wide profiling identifies the THYT1 signature as a distinctive feature of widely metastatic Papillary Thyroid Carcinomas.
Greta Gandolfi, Moira Ragazzi, Dario de Biase, Michela Visani, Eleonora Zanetti, Federica Torricelli, Valentina Sancisi, Mila Gugnoni, Gloria Manzotti, Luca Braglia,[...]. Oncotarget 2017

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency.
Chaoyang Sun, Jun Yin, Yong Fang, Jian Chen, Kang Jin Jeong, Xiaohua Chen, Christopher P Vellano, Zhenlin Ju, Wei Zhao, Dong Zhang,[...]. Cancer Cell 2018

Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells.
Zhanhui Du, Xiuxiang Song, Fangfang Yan, Jingjing Wang, Yuxia Zhao, Shangming Liu. Int J Oncol 2018

Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release.
Wen Liu, Qi Ma, Kaki Wong, Wenbo Li, Kenny Ohgi, Jie Zhang, Aneel Aggarwal, Michael G Rosenfeld. Cell 2013

CDK8 is a positive regulator of transcriptional elongation within the serum response network.
Aaron J Donner, Christopher C Ebmeier, Dylan J Taatjes, Joaquín M Espinosa. Nat Struct Mol Biol 2010

Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.
Sebastian Schröder, Sungyoo Cho, Lei Zeng, Qiang Zhang, Katrin Kaehlcke, Lily Mak, Joann Lau, Dwayne Bisgrove, Martina Schnölzer, Eric Verdin,[...]. J Biol Chem 2012

TERT promoter mutations are associated with distant metastases in papillary thyroid carcinoma.
Greta Gandolfi, Moira Ragazzi, Andrea Frasoldati, Simonetta Piana, Alessia Ciarrocchi, Valentina Sancisi. Eur J Endocrinol 2015

TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013

BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia.
Jae-Seok Roe, Fatih Mercan, Keith Rivera, Darryl J Pappin, Christopher R Vakoc. Mol Cell 2015

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4.
Zhiyuan Yang, Jasper H N Yik, Ruichuan Chen, Nanhai He, Moon Kyoo Jang, Keiko Ozato, Qiang Zhou. Mol Cell 2005

Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer.
Jian Shi, Yifan Wang, Lei Zeng, Yadi Wu, Jiong Deng, Qiang Zhang, Yiwei Lin, Junlin Li, Tiebang Kang, Min Tao,[...]. Cancer Cell 2014

A randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced non-small-cell lung cancer.
A A Chiappori, T Kolevska, D R Spigel, S Hager, M Rarick, S Gadgeel, N Blais, J Von Pawel, L Hart, M Reck,[...]. Ann Oncol 2015

Imetelstat (a telomerase antagonist) exerts off‑target effects on the cytoskeleton.
Ilgen Mender, Serif Senturk, Nuriman Ozgunes, K Can Akcali, Dimitris Kletsas, Sergei Gryaznov, Alp Can, Jerry W Shay, Z Gunnur Dikmen. Int J Oncol 2013

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones.
Tomohiko Kanno, Yuka Kanno, Gary LeRoy, Eric Campos, Hong-Wei Sun, Stephen R Brooks, Golnaz Vahedi, Tom D Heightman, Benjamin A Garcia, Danny Reinberg,[...]. Nat Struct Mol Biol 2014

BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain.
Ballachanda N Devaiah, Brian A Lewis, Natasha Cherman, Michael C Hewitt, Brian K Albrecht, Pamela G Robey, Keiko Ozato, Robert J Sims, Dinah S Singer. Proc Natl Acad Sci U S A 2012

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain.
Jeanne Morinière, Sophie Rousseaux, Ulrich Steuerwald, Montserrat Soler-López, Sandrine Curtet, Anne-Laure Vitte, Jérôme Govin, Jonathan Gaucher, Karin Sadoul, Darren J Hart,[...]. Nature 2009

Structure and ligand of a histone acetyltransferase bromodomain.
C Dhalluin, J E Carlson, L Zeng, C He, A K Aggarwal, M M Zhou. Nature 1999

Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.