Weixing Zhao, Justin B Steinfeld, Fengshan Liang, Xiaoyong Chen, David G Maranon, Chu Jian Ma, Youngho Kwon, Timsi Rao, Weibin Wang, Chen Sheng, Xuemei Song, Yanhong Deng, Judit Jimenez-Sainz, Lucy Lu, Ryan B Jensen, Yong Xiong, Gary M Kupfer, Claudia Wiese, Eric C Greene, Patrick Sung. Nature 2017
Times Cited: 160
Times Cited: 160
Times Cited
Times Co-cited
Similarity
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
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PALB2 is an integral component of the BRCA complex required for homologous recombination repair.
Shirley M H Sy, Michael S Y Huen, Junjie Chen. Proc Natl Acad Sci U S A 2009
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DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
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Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection.
Ruth M Densham, Alexander J Garvin, Helen R Stone, Joanna Strachan, Robert A Baldock, Manuel Daza-Martin, Alice Fletcher, Sarah Blair-Reid, James Beesley, Balraj Johal,[...]. Nat Struct Mol Biol 2016
Ruth M Densham, Alexander J Garvin, Helen R Stone, Joanna Strachan, Robert A Baldock, Manuel Daza-Martin, Alice Fletcher, Sarah Blair-Reid, James Beesley, Balraj Johal,[...]. Nat Struct Mol Biol 2016
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Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
P S Brzovic, P Rajagopal, D W Hoyt, M C King, R E Klevit. Nat Struct Biol 2001
P S Brzovic, P Rajagopal, D W Hoyt, M C King, R E Klevit. Nat Struct Biol 2001
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The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication.
Madalena Tarsounas, Patrick Sung. Nat Rev Mol Cell Biol 2020
Madalena Tarsounas, Patrick Sung. Nat Rev Mol Cell Biol 2020
18
Purified human BRCA2 stimulates RAD51-mediated recombination.
Ryan B Jensen, Aura Carreira, Stephen C Kowalczykowski. Nature 2010
Ryan B Jensen, Aura Carreira, Stephen C Kowalczykowski. Nature 2010
15
Identification of a RING protein that can interact in vivo with the BRCA1 gene product.
L C Wu, Z W Wang, J T Tsan, M A Spillman, A Phung, X L Xu, M C Yang, L Y Hwang, A M Bowcock, R Baer. Nat Genet 1996
L C Wu, Z W Wang, J T Tsan, M A Spillman, A Phung, X L Xu, M C Yang, L Y Hwang, A M Bowcock, R Baer. Nat Genet 1996
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PALB2 links BRCA1 and BRCA2 in the DNA-damage response.
Feng Zhang, Jianglin Ma, Jiaxue Wu, Lin Ye, Hong Cai, Bing Xia, Xiaochun Yu. Curr Biol 2009
Feng Zhang, Jianglin Ma, Jiaxue Wu, Lin Ye, Hong Cai, Bing Xia, Xiaochun Yu. Curr Biol 2009
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Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
Peter Bouwman, Amal Aly, Jose M Escandell, Mark Pieterse, Jirina Bartkova, Hanneke van der Gulden, Sanne Hiddingh, Maria Thanasoula, Atul Kulkarni, Qifeng Yang,[...]. Nat Struct Mol Biol 2010
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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
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14
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Cristina Escribano-Díaz, Alexandre Orthwein, Amélie Fradet-Turcotte, Mengtan Xing, Jordan T F Young, Ján Tkáč, Michael A Cook, Adam P Rosebrock, Meagan Munro, Marella D Canny,[...]. Mol Cell 2013
Cristina Escribano-Díaz, Alexandre Orthwein, Amélie Fradet-Turcotte, Mengtan Xing, Jordan T F Young, Ján Tkáč, Michael A Cook, Adam P Rosebrock, Meagan Munro, Marella D Canny,[...]. Mol Cell 2013
14
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation.
R Hashizume, M Fukuda, I Maeda, H Nishikawa, D Oyake, Y Yabuki, H Ogata, T Ohta. J Biol Chem 2001
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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
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14
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
Bing Xia, Qing Sheng, Koji Nakanishi, Akihiro Ohashi, Jianmin Wu, Nicole Christ, Xinggang Liu, Maria Jasin, Fergus J Couch, David M Livingston. Mol Cell 2006
Bing Xia, Qing Sheng, Koji Nakanishi, Akihiro Ohashi, Jianmin Wu, Nicole Christ, Xinggang Liu, Maria Jasin, Fergus J Couch, David M Livingston. Mol Cell 2006
13
BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair.
Amitabh V Nimonkar, Jochen Genschel, Eri Kinoshita, Piotr Polaczek, Judith L Campbell, Claire Wyman, Paul Modrich, Stephen C Kowalczykowski. Genes Dev 2011
Amitabh V Nimonkar, Jochen Genschel, Eri Kinoshita, Piotr Polaczek, Judith L Campbell, Claire Wyman, Paul Modrich, Stephen C Kowalczykowski. Genes Dev 2011
13
Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation.
Mo Li, Xiaochun Yu. Cancer Cell 2013
Mo Li, Xiaochun Yu. Cancer Cell 2013
13
Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins.
Rohit Prakash, Yu Zhang, Weiran Feng, Maria Jasin. Cold Spring Harb Perspect Biol 2015
Rohit Prakash, Yu Zhang, Weiran Feng, Maria Jasin. Cold Spring Harb Perspect Biol 2015
13
BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.
Rinske Drost, Peter Bouwman, Sven Rottenberg, Ute Boon, Eva Schut, Sjoerd Klarenbeek, Christiaan Klijn, Ingrid van der Heijden, Hanneke van der Gulden, Ellen Wientjens,[...]. Cancer Cell 2011
Rinske Drost, Peter Bouwman, Sven Rottenberg, Ute Boon, Eva Schut, Sjoerd Klarenbeek, Christiaan Klijn, Ingrid van der Heijden, Hanneke van der Gulden, Ellen Wientjens,[...]. Cancer Cell 2011
12
Human CtIP promotes DNA end resection.
Alessandro A Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas, Stephen P Jackson. Nature 2007
Alessandro A Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas, Stephen P Jackson. Nature 2007
12
Mechanism of eukaryotic homologous recombination.
Joseph San Filippo, Patrick Sung, Hannah Klein. Annu Rev Biochem 2008
Joseph San Filippo, Patrick Sung, Hannah Klein. Annu Rev Biochem 2008
12
Homologous recombination and the repair of DNA double-strand breaks.
William Douglass Wright, Shanaya Shital Shah, Wolf-Dietrich Heyer. J Biol Chem 2018
William Douglass Wright, Shanaya Shital Shah, Wolf-Dietrich Heyer. J Biol Chem 2018
12
The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
Stephen P Jackson, Jiri Bartek. Nature 2009
12
The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
12
The shieldin complex mediates 53BP1-dependent DNA repair.
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
12
Association of BRCA1 with Rad51 in mitotic and meiotic cells.
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12
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
11
BRCA1 and BRCA2: different roles in a common pathway of genome protection.
Rohini Roy, Jarin Chun, Simon N Powell. Nat Rev Cancer 2011
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11
ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
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11
BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
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11
BRCA1 accelerates CtIP-mediated DNA-end resection.
Andrés Cruz-García, Ana López-Saavedra, Pablo Huertas. Cell Rep 2014
Andrés Cruz-García, Ana López-Saavedra, Pablo Huertas. Cell Rep 2014
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New concepts on BARD1: Regulator of BRCA pathways and beyond.
Irmgard Irminger-Finger, Magda Ratajska, Maxim Pilyugin. Int J Biochem Cell Biol 2016
Irmgard Irminger-Finger, Magda Ratajska, Maxim Pilyugin. Int J Biochem Cell Biol 2016
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Linkage of early-onset familial breast cancer to chromosome 17q21.
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11
H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.
Kyosuke Nakamura, Giulia Saredi, Jordan R Becker, Benjamin M Foster, Nhuong V Nguyen, Tracey E Beyer, Laura C Cesa, Peter A Faull, Saulius Lukauskas, Thomas Frimurer,[...]. Nat Cell Biol 2019
Kyosuke Nakamura, Giulia Saredi, Jordan R Becker, Benjamin M Foster, Nhuong V Nguyen, Tracey E Beyer, Laura C Cesa, Peter A Faull, Saulius Lukauskas, Thomas Frimurer,[...]. Nat Cell Biol 2019
14
Replication fork stability confers chemoresistance in BRCA-deficient cells.
Arnab Ray Chaudhuri, Elsa Callen, Xia Ding, Ewa Gogola, Alexandra A Duarte, Ji-Eun Lee, Nancy Wong, Vanessa Lafarga, Jennifer A Calvo, Nicholas J Panzarino,[...]. Nature 2016
Arnab Ray Chaudhuri, Elsa Callen, Xia Ding, Ewa Gogola, Alexandra A Duarte, Ji-Eun Lee, Nancy Wong, Vanessa Lafarga, Jennifer A Calvo, Nicholas J Panzarino,[...]. Nature 2016
11
BRCA1, a 'complex' protein involved in the maintenance of genomic stability.
Kienan I Savage, D Paul Harkin. FEBS J 2015
Kienan I Savage, D Paul Harkin. FEBS J 2015
10
Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.
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10
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.
Bijan Sobhian, Genze Shao, Dana R Lilli, Aedín C Culhane, Lisa A Moreau, Bing Xia, David M Livingston, Roger A Greenberg. Science 2007
Bijan Sobhian, Genze Shao, Dana R Lilli, Aedín C Culhane, Lisa A Moreau, Bing Xia, David M Livingston, Roger A Greenberg. Science 2007
10
The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination.
Weixing Zhao, Claudia Wiese, Youngho Kwon, Robert Hromas, Patrick Sung. Annu Rev Biochem 2019
Weixing Zhao, Claudia Wiese, Youngho Kwon, Robert Hromas, Patrick Sung. Annu Rev Biochem 2019
17
Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.
Katharina Schlacher, Nicole Christ, Nicolas Siaud, Akinori Egashira, Hong Wu, Maria Jasin. Cell 2011
Katharina Schlacher, Nicole Christ, Nicolas Siaud, Akinori Egashira, Hong Wu, Maria Jasin. Cell 2011
9
A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.
Katharina Schlacher, Hong Wu, Maria Jasin. Cancer Cell 2012
Katharina Schlacher, Hong Wu, Maria Jasin. Cancer Cell 2012
9
BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.
Elodie Hatchi, Konstantina Skourti-Stathaki, Steffen Ventz, Luca Pinello, Angela Yen, Kinga Kamieniarz-Gdula, Stoil Dimitrov, Shailja Pathania, Kristine M McKinney, Matthew L Eaton,[...]. Mol Cell 2015
Elodie Hatchi, Konstantina Skourti-Stathaki, Steffen Ventz, Luca Pinello, Angela Yen, Kinga Kamieniarz-Gdula, Stoil Dimitrov, Shailja Pathania, Kristine M McKinney, Matthew L Eaton,[...]. Mol Cell 2015
9
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.
Maximina H Yun, Kevin Hiom. Nature 2009
Maximina H Yun, Kevin Hiom. Nature 2009
9
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.
Bin Wang, Shuhei Matsuoka, Bryan A Ballif, Dong Zhang, Agata Smogorzewska, Steven P Gygi, Stephen J Elledge. Science 2007
Bin Wang, Shuhei Matsuoka, Bryan A Ballif, Dong Zhang, Agata Smogorzewska, Steven P Gygi, Stephen J Elledge. Science 2007
9
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.
J Ross Chapman, Alex J Sossick, Simon J Boulton, Stephen P Jackson. J Cell Sci 2012
J Ross Chapman, Alex J Sossick, Simon J Boulton, Stephen P Jackson. J Cell Sci 2012
9
BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes.
Mikaela D Stewart, Elena Zelin, Abhinav Dhall, Tom Walsh, Esha Upadhyay, Jacob E Corn, Champak Chatterjee, Mary-Claire King, Rachel E Klevit. Proc Natl Acad Sci U S A 2018
Mikaela D Stewart, Elena Zelin, Abhinav Dhall, Tom Walsh, Esha Upadhyay, Jacob E Corn, Champak Chatterjee, Mary-Claire King, Rachel E Klevit. Proc Natl Acad Sci U S A 2018
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BRCA1 is a histone-H2A-specific ubiquitin ligase.
Reinhard Kalb, Donna L Mallery, Conor Larkin, Jeffrey T J Huang, Kevin Hiom. Cell Rep 2014
Reinhard Kalb, Donna L Mallery, Conor Larkin, Jeffrey T J Huang, Kevin Hiom. Cell Rep 2014
10
Brca1 controls homology-directed DNA repair.
M E Moynahan, J W Chiu, B H Koller, M Jasin. Mol Cell 1999
M E Moynahan, J W Chiu, B H Koller, M Jasin. Mol Cell 1999
9
Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability.
Ellen E McCarthy, Julide T Celebi, Richard Baer, Thomas Ludwig. Mol Cell Biol 2003
Ellen E McCarthy, Julide T Celebi, Richard Baer, Thomas Ludwig. Mol Cell Biol 2003
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.