S M Carroll, M L DeRose, P Gaudray, C M Moore, D R Needham-Vandevanter, D D Von Hoff, G M Wahl. Mol Cell Biol 1988
Times Cited: 181
Times Cited: 181
Times Cited
Times Co-cited
Similarity
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure.
Clelia Tiziana Storlazzi, Angelo Lonoce, Maria C Guastadisegni, Domenico Trombetta, Pietro D'Addabbo, Giulia Daniele, Alberto L'Abbate, Gemma Macchia, Cecilia Surace, Klaas Kok,[...]. Genome Res 2010
Clelia Tiziana Storlazzi, Angelo Lonoce, Maria C Guastadisegni, Domenico Trombetta, Pietro D'Addabbo, Giulia Daniele, Alberto L'Abbate, Gemma Macchia, Cecilia Surace, Klaas Kok,[...]. Genome Res 2010
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Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity.
Kristen M Turner, Viraj Deshpande, Doruk Beyter, Tomoyuki Koga, Jessica Rusert, Catherine Lee, Bin Li, Karen Arden, Bing Ren, David A Nathanson,[...]. Nature 2017
Kristen M Turner, Viraj Deshpande, Doruk Beyter, Tomoyuki Koga, Jessica Rusert, Catherine Lee, Bin Li, Karen Arden, Bing Ren, David A Nathanson,[...]. Nature 2017
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Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.
David A Nathanson, Beatrice Gini, Jack Mottahedeh, Koppany Visnyei, Tomoyuki Koga, German Gomez, Ascia Eskin, Kiwook Hwang, Jun Wang, Kenta Masui,[...]. Science 2014
David A Nathanson, Beatrice Gini, Jack Mottahedeh, Koppany Visnyei, Tomoyuki Koga, German Gomez, Ascia Eskin, Kiwook Hwang, Jun Wang, Kenta Masui,[...]. Science 2014
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Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas.
Nicolas Vogt, Sandrine-Hélène Lefèvre, Françoise Apiou, Anne-Marie Dutrillaux, Andrej Cör, Pascal Leuraud, Marie-France Poupon, Bernard Dutrillaux, Michelle Debatisse, Bernard Malfoy. Proc Natl Acad Sci U S A 2004
Nicolas Vogt, Sandrine-Hélène Lefèvre, Françoise Apiou, Anne-Marie Dutrillaux, Andrej Cör, Pascal Leuraud, Marie-France Poupon, Bernard Dutrillaux, Michelle Debatisse, Bernard Malfoy. Proc Natl Acad Sci U S A 2004
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MINUTE CHROMATIN BODIES IN MALIGNANT TUMOURS OF CHILDHOOD.
D COX, C YUNCKEN, A I SPRIGGS. Lancet 1965
D COX, C YUNCKEN, A I SPRIGGS. Lancet 1965
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Circular ecDNA promotes accessible chromatin and high oncogene expression.
Sihan Wu, Kristen M Turner, Nam Nguyen, Ramya Raviram, Marcella Erb, Jennifer Santini, Jens Luebeck, Utkrisht Rajkumar, Yarui Diao, Bin Li,[...]. Nature 2019
Sihan Wu, Kristen M Turner, Nam Nguyen, Ramya Raviram, Marcella Erb, Jennifer Santini, Jens Luebeck, Utkrisht Rajkumar, Yarui Diao, Bin Li,[...]. Nature 2019
25
24
MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene.
Clelia Tiziana Storlazzi, Thoas Fioretos, Cecilia Surace, Angelo Lonoce, Angela Mastrorilli, Bodil Strömbeck, Pietro D'Addabbo, Francesco Iacovelli, Crescenzio Minervini, Anna Aventin,[...]. Hum Mol Genet 2006
Clelia Tiziana Storlazzi, Thoas Fioretos, Cecilia Surace, Angelo Lonoce, Angela Mastrorilli, Bodil Strömbeck, Pietro D'Addabbo, Francesco Iacovelli, Crescenzio Minervini, Anna Aventin,[...]. Hum Mol Genet 2006
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Massive genomic rearrangement acquired in a single catastrophic event during cancer development.
Philip J Stephens, Chris D Greenman, Beiyuan Fu, Fengtang Yang, Graham R Bignell, Laura J Mudie, Erin D Pleasance, King Wai Lau, David Beare, Lucy A Stebbings,[...]. Cell 2011
Philip J Stephens, Chris D Greenman, Beiyuan Fu, Fengtang Yang, Graham R Bignell, Laura J Mudie, Erin D Pleasance, King Wai Lau, David Beare, Lucy A Stebbings,[...]. Cell 2011
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Extrachromosomal oncogene amplification in tumour pathogenesis and evolution.
Roel G W Verhaak, Vineet Bafna, Paul S Mischel. Nat Rev Cancer 2019
Roel G W Verhaak, Vineet Bafna, Paul S Mischel. Nat Rev Cancer 2019
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Elimination of extrachromosomally amplified MYC genes from human tumor cells reduces their tumorigenicity.
D D Von Hoff, J R McGill, B J Forseth, K K Davidson, T P Bradley, D R Van Devanter, G M Wahl. Proc Natl Acad Sci U S A 1992
D D Von Hoff, J R McGill, B J Forseth, K K Davidson, T P Bradley, D R Van Devanter, G M Wahl. Proc Natl Acad Sci U S A 1992
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Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma.
Ana C deCarvalho, Hoon Kim, Laila M Poisson, Mary E Winn, Claudius Mueller, David Cherba, Julie Koeman, Sahil Seth, Alexei Protopopov, Michelle Felicella,[...]. Nat Genet 2018
Ana C deCarvalho, Hoon Kim, Laila M Poisson, Mary E Winn, Claudius Mueller, David Cherba, Julie Koeman, Sahil Seth, Alexei Protopopov, Michelle Felicella,[...]. Nat Genet 2018
23
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Richard P Koche, Elias Rodriguez-Fos, Konstantin Helmsauer, Martin Burkert, Ian C MacArthur, Jesper Maag, Rocio Chamorro, Natalia Munoz-Perez, Montserrat Puiggròs, Heathcliff Dorado Garcia,[...]. Nat Genet 2020
Richard P Koche, Elias Rodriguez-Fos, Konstantin Helmsauer, Martin Burkert, Ian C MacArthur, Jesper Maag, Rocio Chamorro, Natalia Munoz-Perez, Montserrat Puiggròs, Heathcliff Dorado Garcia,[...]. Nat Genet 2020
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Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.
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Andrew R Morton, Nergiz Dogan-Artun, Zachary J Faber, Graham MacLeod, Cynthia F Bartels, Megan S Piazza, Kevin C Allan, Stephen C Mack, Xiuxing Wang, Ryan C Gimple,[...]. Cell 2019
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Characterization of an episome produced in hamster cells that amplify a transfected CAD gene at high frequency: functional evidence for a mammalian replication origin.
S M Carroll, P Gaudray, M L De Rose, J F Emery, J L Meinkoth, E Nakkim, M Subler, D D Von Hoff, G M Wahl. Mol Cell Biol 1987
S M Carroll, P Gaudray, M L De Rose, J F Emery, J L Meinkoth, E Nakkim, M Subler, D D Von Hoff, G M Wahl. Mol Cell Biol 1987
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Extrachromosomal microDNAs and chromosomal microdeletions in normal tissues.
Yoshiyuki Shibata, Pankaj Kumar, Ryan Layer, Smaranda Willcox, Jeffrey R Gagan, Jack D Griffith, Anindya Dutta. Science 2012
Yoshiyuki Shibata, Pankaj Kumar, Ryan Layer, Smaranda Willcox, Jeffrey R Gagan, Jack D Griffith, Anindya Dutta. Science 2012
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Amplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules.
D D Von Hoff, D R Needham-VanDevanter, J Yucel, B E Windle, G M Wahl. Proc Natl Acad Sci U S A 1988
D D Von Hoff, D R Needham-VanDevanter, J Yucel, B E Windle, G M Wahl. Proc Natl Acad Sci U S A 1988
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Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer.
Alberto L'Abbate, Gemma Macchia, Pietro D'Addabbo, Angelo Lonoce, Doron Tolomeo, Domenico Trombetta, Klaas Kok, Christoph Bartenhagen, Christopher W Whelan, Orazio Palumbo,[...]. Nucleic Acids Res 2014
Alberto L'Abbate, Gemma Macchia, Pietro D'Addabbo, Angelo Lonoce, Doron Tolomeo, Domenico Trombetta, Klaas Kok, Christoph Bartenhagen, Christopher W Whelan, Orazio Palumbo,[...]. Nucleic Acids Res 2014
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Extrachromosomal circular DNA is common in yeast.
Henrik D Møller, Lance Parsons, Tue S Jørgensen, David Botstein, Birgitte Regenberg. Proc Natl Acad Sci U S A 2015
Henrik D Møller, Lance Parsons, Tue S Jørgensen, David Botstein, Birgitte Regenberg. Proc Natl Acad Sci U S A 2015
20
Circular DNA elements of chromosomal origin are common in healthy human somatic tissue.
Henrik Devitt Møller, Marghoob Mohiyuddin, Iñigo Prada-Luengo, M Reza Sailani, Jens Frey Halling, Peter Plomgaard, Lasse Maretty, Anders Johannes Hansen, Michael P Snyder, Henriette Pilegaard,[...]. Nat Commun 2018
Henrik Devitt Møller, Marghoob Mohiyuddin, Iñigo Prada-Luengo, M Reza Sailani, Jens Frey Halling, Peter Plomgaard, Lasse Maretty, Anders Johannes Hansen, Michael P Snyder, Henriette Pilegaard,[...]. Nat Commun 2018
20
A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration.
B Windle, B W Draper, Y X Yin, S O'Gorman, G M Wahl. Genes Dev 1991
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Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations.
Tobias Rausch, David T W Jones, Marc Zapatka, Adrian M Stütz, Thomas Zichner, Joachim Weischenfeldt, Natalie Jäger, Marc Remke, David Shih, Paul A Northcott,[...]. Cell 2012
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Chromothripsis from DNA damage in micronuclei.
Cheng-Zhong Zhang, Alexander Spektor, Hauke Cornils, Joshua M Francis, Emily K Jackson, Shiwei Liu, Matthew Meyerson, David Pellman. Nature 2015
Cheng-Zhong Zhang, Alexander Spektor, Hauke Cornils, Joshua M Francis, Emily K Jackson, Shiwei Liu, Matthew Meyerson, David Pellman. Nature 2015
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Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation.
Pankaj Kumar, Laura W Dillon, Yoshiyuki Shibata, Amir A Jazaeri, David R Jones, Anindya Dutta. Mol Cancer Res 2017
Pankaj Kumar, Laura W Dillon, Yoshiyuki Shibata, Amir A Jazaeri, David R Jones, Anindya Dutta. Mol Cancer Res 2017
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Exploring the landscape of focal amplifications in cancer using AmpliconArchitect.
Viraj Deshpande, Jens Luebeck, Nam-Phuong D Nguyen, Mehrdad Bakhtiari, Kristen M Turner, Richard Schwab, Hannah Carter, Paul S Mischel, Vineet Bafna. Nat Commun 2019
Viraj Deshpande, Jens Luebeck, Nam-Phuong D Nguyen, Mehrdad Bakhtiari, Kristen M Turner, Richard Schwab, Hannah Carter, Paul S Mischel, Vineet Bafna. Nat Commun 2019
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Double minutes arise from circular extrachromosomal DNA intermediates which integrate into chromosomal sites in human HL-60 leukemia cells.
D D Von Hoff, B Forseth, C N Clare, K L Hansen, D VanDevanter. J Clin Invest 1990
D D Von Hoff, B Forseth, C N Clare, K L Hansen, D VanDevanter. J Clin Invest 1990
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Autonomously replicating episomes contain mdr1 genes in a multidrug-resistant human cell line.
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J C Ruiz, K H Choi, D D von Hoff, I B Roninson, G M Wahl. Mol Cell Biol 1989
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Criteria for inference of chromothripsis in cancer genomes.
Jan O Korbel, Peter J Campbell. Cell 2013
Jan O Korbel, Peter J Campbell. Cell 2013
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Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity.
Laura W Dillon, Pankaj Kumar, Yoshiyuki Shibata, Yuh-Hwa Wang, Smaranda Willcox, Jack D Griffith, Yves Pommier, Shunichi Takeda, Anindya Dutta. Cell Rep 2015
Laura W Dillon, Pankaj Kumar, Yoshiyuki Shibata, Yuh-Hwa Wang, Smaranda Willcox, Jack D Griffith, Yves Pommier, Shunichi Takeda, Anindya Dutta. Cell Rep 2015
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Discoveries of Extrachromosomal Circles of DNA in Normal and Tumor Cells.
Teressa Paulsen, Pankaj Kumar, M Murat Koseoglu, Anindya Dutta. Trends Genet 2018
Teressa Paulsen, Pankaj Kumar, M Murat Koseoglu, Anindya Dutta. Trends Genet 2018
25
Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma.
Nicolas Vogt, Anne Gibaud, Frédéric Lemoine, Pierre de la Grange, Michelle Debatisse, Bernard Malfoy. Nucleic Acids Res 2014
Nicolas Vogt, Anne Gibaud, Frédéric Lemoine, Pierre de la Grange, Michelle Debatisse, Bernard Malfoy. Nucleic Acids Res 2014
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Inhibiting homologous recombination decreases extrachromosomal amplification but has no effect on intrachromosomal amplification in methotrexate-resistant colon cancer cells.
Mengdi Cai, Huishu Zhang, Liqing Hou, Wei Gao, Ying Song, Xiaobo Cui, Chunxiang Li, Rongwei Guan, Jinfa Ma, Xu Wang,[...]. Int J Cancer 2019
Mengdi Cai, Huishu Zhang, Liqing Hou, Wei Gao, Ying Song, Xiaobo Cui, Chunxiang Li, Rongwei Guan, Jinfa Ma, Xu Wang,[...]. Int J Cancer 2019
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Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers.
Hoon Kim, Nam-Phuong Nguyen, Kristen Turner, Sihan Wu, Amit D Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi,[...]. Nat Genet 2020
Hoon Kim, Nam-Phuong Nguyen, Kristen Turner, Sihan Wu, Amit D Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi,[...]. Nat Genet 2020
21
Double minute chromosomes and homogeneously staining regions in tumors taken directly from patients versus in human tumor cell lines.
S E Benner, G M Wahl, D D Von Hoff. Anticancer Drugs 1991
S E Benner, G M Wahl, D D Von Hoff. Anticancer Drugs 1991
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Novel submicroscopic extrachromosomal elements containing amplified genes in human cells.
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Mitotic segregation of viral and cellular acentric extrachromosomal molecules by chromosome tethering.
T Kanda, M Otter, G M Wahl. J Cell Sci 2001
T Kanda, M Otter, G M Wahl. J Cell Sci 2001
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Translocation-excision-deletion-amplification mechanism leading to nonsyntenic coamplification of MYC and ATBF1.
Nadine Van Roy, Jo Vandesompele, Björn Menten, Helén Nilsson, Els De Smet, Mariano Rocchi, Anne De Paepe, Sven Påhlman, Frank Speleman. Genes Chromosomes Cancer 2006
Nadine Van Roy, Jo Vandesompele, Björn Menten, Helén Nilsson, Els De Smet, Mariano Rocchi, Anne De Paepe, Sven Påhlman, Frank Speleman. Genes Chromosomes Cancer 2006
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Extrachromosomal circular DNAs and genomic sequence plasticity in eukaryotic cells.
J W Gaubatz. Mutat Res 1990
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Small polydispersed circular DNA (spcDNA) in human cells: association with genomic instability.
S Cohen, A Regev, S Lavi. Oncogene 1997
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Frequency of double minute chromosomes and combined cytogenetic abnormalities and their characteristics.
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Yihui Fan, Renfang Mao, Hongpei Lv, Jie Xu, Lei Yan, Yanhong Liu, Meng Shi, Guohua Ji, Yang Yu, Jing Bai,[...]. J Appl Genet 2011
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Transposition and amplification of oncogene-related sequences in human neuroblastomas.
N E Kohl, N Kanda, R R Schreck, G Bruns, S A Latt, F Gilbert, F W Alt. Cell 1983
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Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks.
M J Singer, L D Mesner, C L Friedman, B J Trask, J L Hamlin. Proc Natl Acad Sci U S A 2000
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14
Extrachromosomal amplification mechanisms in a glioma with amplified sequences from multiple chromosome loci.
Anne Gibaud, Nicolas Vogt, Nabila-Sandra Hadj-Hamou, Jean-Philippe Meyniel, Philippe Hupé, Michelle Debatisse, Bernard Malfoy. Hum Mol Genet 2010
Anne Gibaud, Nicolas Vogt, Nabila-Sandra Hadj-Hamou, Jean-Philippe Meyniel, Philippe Hupé, Michelle Debatisse, Bernard Malfoy. Hum Mol Genet 2010
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The architecture and evolution of cancer neochromosomes.
Dale W Garsed, Owen J Marshall, Vincent D A Corbin, Arthur Hsu, Leon Di Stefano, Jan Schröder, Jason Li, Zhi-Ping Feng, Bo W Kim, Mark Kowarsky,[...]. Cancer Cell 2014
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13
Extrachromosomal driver mutations in glioblastoma and low-grade glioma.
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Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells.
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MOLECULAR SIZE AND CIRCULARITY OF DNA IN CELLS OF MAMMALS AND HIGHER PLANTS.
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Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
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Konstantin Helmsauer, Maria E Valieva, Salaheddine Ali, Rocío Chamorro González, Robert Schöpflin, Claudia Röefzaad, Yi Bei, Heathcliff Dorado Garcia, Elias Rodriguez-Fos, Montserrat Puiggròs,[...]. Nat Commun 2020
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A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs.
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Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomes.
D A Haber, R T Schimke. Cell 1981
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13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.