A citation-based method for searching scientific literature

Brandon Faubert, Kevin Y Li, Ling Cai, Christopher T Hensley, Jiyeon Kim, Lauren G Zacharias, Chendong Yang, Quyen N Do, Sarah Doucette, Daniel Burguete, Hong Li, Giselle Huet, Qing Yuan, Trevor Wigal, Yasmeen Butt, Min Ni, Jose Torrealba, Dwight Oliver, Robert E Lenkinski, Craig R Malloy, Jason W Wachsmann, Jamey D Young, Kemp Kernstine, Ralph J DeBerardinis. Cell 2017
Times Cited: 537







List of co-cited articles
1168 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo,[...]. Nature 2017
576
48

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
24

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
23

Metabolic Heterogeneity in Human Lung Tumors.
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
568
23

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
Pierre Sonveaux, Frédérique Végran, Thies Schroeder, Melanie C Wergin, Julien Verrax, Zahid N Rabbani, Christophe J De Saedeleer, Kelly M Kennedy, Caroline Diepart, Bénédicte F Jordan,[...]. J Clin Invest 2008
19

On the origin of cancer cells.
O WARBURG. Science 1956
19

Metabolic heterogeneity confers differences in melanoma metastatic potential.
Alpaslan Tasdogan, Brandon Faubert, Vijayashree Ramesh, Jessalyn M Ubellacker, Bo Shen, Ashley Solmonson, Malea M Murphy, Zhimin Gu, Wen Gu, Misty Martin,[...]. Nature 2020
140
16

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
286
16

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Almut Brand, Katrin Singer, Gudrun E Koehl, Marlene Kolitzus, Gabriele Schoenhammer, Annette Thiel, Carina Matos, Christina Bruss, Sebastian Klobuch, Katrin Peter,[...]. Cell Metab 2016
611
15

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
14

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Oscar R Colegio, Ngoc-Quynh Chu, Alison L Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E Brokowski, Stephanie C Eisenbarth, Gillian M Phillips,[...]. Nature 2014
14

Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
939
14

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
14

Metabolic regulation of gene expression by histone lactylation.
Di Zhang, Zhanyun Tang, He Huang, Guolin Zhou, Chang Cui, Yejing Weng, Wenchao Liu, Sunjoo Kim, Sangkyu Lee, Mathew Perez-Neut,[...]. Nature 2019
448
13

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
13

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.
Lucas B Sullivan, Dan Y Gui, Aaron M Hosios, Lauren N Bush, Elizaveta Freinkman, Matthew G Vander Heiden. Cell 2015
566
13

Metabolic reprogramming and cancer progression.
Brandon Faubert, Ashley Solmonson, Ralph J DeBerardinis. Science 2020
342
13

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
13

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Shawn M Davidson, Thales Papagiannakopoulos, Benjamin A Olenchock, Julia E Heyman, Mark A Keibler, Alba Luengo, Matthew R Bauer, Abhishek K Jha, James P O'Brien, Kerry A Pierce,[...]. Cell Metab 2016
436
12

Reductive carboxylation supports redox homeostasis during anchorage-independent growth.
Lei Jiang, Alexander A Shestov, Pamela Swain, Chendong Yang, Seth J Parker, Qiong A Wang, Lance S Terada, Nicholas D Adams, Michael T McCabe, Beth Pietrak,[...]. Nature 2016
311
11

Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass.
Jessica B Spinelli, Haejin Yoon, Alison E Ringel, Sarah Jeanfavre, Clary B Clish, Marcia C Haigis. Science 2017
169
11

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
11

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Kıvanç Birsoy, Tim Wang, Walter W Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M Sabatini. Cell 2015
642
11

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
11

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Ping-Chih Ho, Jessica Dauz Bihuniak, Andrew N Macintyre, Matthew Staron, Xiaojing Liu, Robert Amezquita, Yao-Chen Tsui, Guoliang Cui, Goran Micevic, Jose C Perales,[...]. Cell 2015
716
10

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
548
10

We need to talk about the Warburg effect.
Ralph J DeBerardinis, Navdeep S Chandel. Nat Metab 2020
177
10

Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
10

Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis.
Joanne R Doherty, Chunying Yang, Kristen E N Scott, Michael D Cameron, Mohammad Fallahi, Weimin Li, Mark A Hall, Antonio L Amelio, Jitendra K Mishra, Fangzheng Li,[...]. Cancer Res 2014
216
9

Lactate metabolism is associated with mammalian mitochondria.
Ying-Jr Chen, Nathaniel G Mahieu, Xiaojing Huang, Manmilan Singh, Peter A Crawford, Stephen L Johnson, Richard W Gross, Jacob Schaefer, Gary J Patti. Nat Chem Biol 2016
136
9

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma.
Stephanos Pavlides, Diana Whitaker-Menezes, Remedios Castello-Cros, Neal Flomenberg, Agnieszka K Witkiewicz, Philippe G Frank, Mathew C Casimiro, Chenguang Wang, Paolo Fortina, Sankar Addya,[...]. Cell Cycle 2009
816
9

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
9

Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Andrew R Mullen, William W Wheaton, Eunsook S Jin, Pei-Hsuan Chen, Lucas B Sullivan, Tzuling Cheng, Youfeng Yang, W Marston Linehan, Navdeep S Chandel, Ralph J DeBerardinis. Nature 2011
823
9

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.
Ruoning Wang, Christopher P Dillon, Lewis Zhichang Shi, Sandra Milasta, Robert Carter, David Finkelstein, Laura L McCormick, Patrick Fitzgerald, Hongbo Chi, Joshua Munger,[...]. Immunity 2011
8

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.
Jurre J Kamphorst, Michel Nofal, Cosimo Commisso, Sean R Hackett, Wenyun Lu, Elda Grabocka, Matthew G Vander Heiden, George Miller, Jeffrey A Drebin, Dafna Bar-Sagi,[...]. Cancer Res 2015
435
8

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Jared R Mayers, Margaret E Torrence, Laura V Danai, Thales Papagiannakopoulos, Shawn M Davidson, Matthew R Bauer, Allison N Lau, Brian W Ji, Purushottam D Dixit, Aaron M Hosios,[...]. Science 2016
305
8

Posttranscriptional control of T cell effector function by aerobic glycolysis.
Chih-Hao Chang, Jonathan D Curtis, Leonard B Maggi, Brandon Faubert, Alejandro V Villarino, David O'Sullivan, Stanley Ching-Cheng Huang, Gerritje J W van der Windt, Julianna Blagih, Jing Qiu,[...]. Cell 2013
8

Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.
Han Xie, Jun-Ichi Hanai, Jian-Guo Ren, Lev Kats, Kerri Burgess, Parul Bhargava, Sabina Signoretti, Julia Billiard, Kevin J Duffy, Aaron Grant,[...]. Cell Metab 2014
290
8

Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours.
Javier Garcia-Bermudez, Lou Baudrier, Konnor La, Xiphias Ge Zhu, Justine Fidelin, Vladislav O Sviderskiy, Thales Papagiannakopoulos, Henrik Molina, Matija Snuderl, Caroline A Lewis,[...]. Nat Cell Biol 2018
156
8

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.
Dan Y Gui, Lucas B Sullivan, Alba Luengo, Aaron M Hosios, Lauren N Bush, Nadege Gitego, Shawn M Davidson, Elizaveta Freinkman, Craig J Thomas, Matthew G Vander Heiden. Cell Metab 2016
178
8

Oxidative stress inhibits distant metastasis by human melanoma cells.
Elena Piskounova, Michalis Agathocleous, Malea M Murphy, Zeping Hu, Sara E Huddlestun, Zhiyu Zhao, A Marilyn Leitch, Timothy M Johnson, Ralph J DeBerardinis, Sean J Morrison. Nature 2015
633
8

Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis.
Stefan Christen, Doriane Lorendeau, Roberta Schmieder, Dorien Broekaert, Kristine Metzger, Koen Veys, Ilaria Elia, Joerg Martin Buescher, Martin Franz Orth, Shawn Michael Davidson,[...]. Cell Rep 2016
135
8


Acetate is a bioenergetic substrate for human glioblastoma and brain metastases.
Tomoyuki Mashimo, Kumar Pichumani, Vamsidhara Vemireddy, Kimmo J Hatanpaa, Dinesh Kumar Singh, Shyam Sirasanagandla, Suraj Nannepaga, Sara G Piccirillo, Zoltan Kovacs, Chan Foong,[...]. Cell 2014
420
8

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Cosimo Commisso, Shawn M Davidson, Rengin G Soydaner-Azeloglu, Seth J Parker, Jurre J Kamphorst, Sean Hackett, Elda Grabocka, Michel Nofal, Jeffrey A Drebin, Craig B Thompson,[...]. Nature 2013
918
8

Lactate: the ugly duckling of energy metabolism.
Joshua D Rabinowitz, Sven Enerbäck. Nat Metab 2020
90
8

Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches.
Karen G de la Cruz-López, Leonardo Josué Castro-Muñoz, Diego O Reyes-Hernández, Alejandro García-Carrancá, Joaquín Manzo-Merino. Front Oncol 2019
199
7

Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay.
Tania Fiaschi, Alberto Marini, Elisa Giannoni, Maria Letizia Taddei, Paolo Gandellini, Alina De Donatis, Michele Lanciotti, Sergio Serni, Paolo Cirri, Paola Chiarugi. Cancer Res 2012
346
7

Targeting lactate metabolism for cancer therapeutics.
Joanne R Doherty, John L Cleveland. J Clin Invest 2013
594
7

Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.
Kelly M Kennedy, Peter M Scarbrough, Anthony Ribeiro, Rachel Richardson, Hong Yuan, Pierre Sonveaux, Chelsea D Landon, Jen-Tsan Chi, Salvatore Pizzo, Thies Schroeder,[...]. PLoS One 2013
118
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.