A citation-based method for searching scientific literature

Hua Jiang, Hongbin He, Yun Chen, Wei Huang, Jinbo Cheng, Jin Ye, Aoli Wang, Jinhui Tao, Chao Wang, Qingsong Liu, Tengchuan Jin, Wei Jiang, Xianming Deng, Rongbin Zhou. J Exp Med 2017
Times Cited: 265







List of co-cited articles
966 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
65

Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
Hongbin He, Hua Jiang, Yun Chen, Jin Ye, Aoli Wang, Chao Wang, Qingsong Liu, Gaolin Liang, Xianming Deng, Wei Jiang,[...]. Nat Commun 2018
219
45

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.
Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang,[...]. EMBO Mol Med 2018
170
44

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
265
42

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Carlo Marchetti, Benjamin Swartzwelter, Fabia Gamboni, Charles P Neff, Katrin Richter, Tania Azam, Sonia Carta, Isak Tengesdal, Travis Nemkov, Angelo D'Alessandro,[...]. Proc Natl Acad Sci U S A 2018
172
39

The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
37

Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome.
Christine Juliana, Teresa Fernandes-Alnemri, Jianghong Wu, Pinaki Datta, Leobaldo Solorzano, Je-Wook Yu, Rong Meng, Andrew A Quong, Eicke Latz, Charles P Scott,[...]. J Biol Chem 2010
346
30

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
Yuan He, Melody Y Zeng, Dahai Yang, Benny Motro, Gabriel Núñez. Nature 2016
510
28

Targeting the NLRP3 inflammasome in inflammatory diseases.
Matthew S J Mangan, Edward J Olhava, William R Roush, H Martin Seidel, Gary D Glick, Eicke Latz. Nat Rev Drug Discov 2018
486
27

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.
Mohamed Lamkanfi, James L Mueller, Alberto C Vitari, Shahram Misaghi, Anna Fedorova, Kurt Deshayes, Wyne P Lee, Hal M Hoffman, Vishva M Dixit. J Cell Biol 2009
529
26

A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
26

Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
25

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
25

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Peter Duewell, Hajime Kono, Katey J Rayner, Cherilyn M Sirois, Gregory Vladimer, Franz G Bauernfeind, George S Abela, Luigi Franchi, Gabriel Nuñez, Max Schnurr,[...]. Nature 2010
24

3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.
Yuan He, Saranyaraajan Varadarajan, Raúl Muñoz-Planillo, Aaron Burberry, Yuumi Nakamura, Gabriel Núñez. J Biol Chem 2014
143
24

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
24

Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
22

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
21

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Michael T Heneka, Markus P Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira-Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te-Chen Tzeng,[...]. Nature 2013
20

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Yun-Hee Youm, Kim Y Nguyen, Ryan W Grant, Emily L Goldberg, Monica Bodogai, Dongin Kim, Dominic D'Agostino, Noah Planavsky, Christopher Lupfer, Thirumala D Kanneganti,[...]. Nat Med 2015
814
20

The inflammasomes.
Kate Schroder, Jurg Tschopp. Cell 2010
19

MCC950 closes the active conformation of NLRP3 to an inactive state.
Ana Tapia-Abellán, Diego Angosto-Bazarra, Helios Martínez-Banaclocha, Carlos de Torre-Minguela, Jose P Cerón-Carrasco, Horacio Pérez-Sánchez, Juan I Arostegui, Pablo Pelegrin. Nat Chem Biol 2019
129
19

Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
18


Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors.
Yang Yang, Huanan Wang, Mohammed Kouadir, Houhui Song, Fushan Shi. Cell Death Dis 2019
430
17

Pharmacological Inhibitors of the NLRP3 Inflammasome.
Ayesha Zahid, Bofeng Li, Arnaud John Kombe Kombe, Tengchuan Jin, Jinhui Tao. Front Immunol 2019
203
17

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
Alvin Lu, Venkat Giri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K Atianand, Matthijn R Vos, Gunnar F Schröder, Katherine A Fitzgerald, Hao Wu, Edward H Egelman. Cell 2014
689
16

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
16

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease.
Mattia Cocco, Carolina Pellegrini, Helios Martínez-Banaclocha, Marta Giorgis, Elisabetta Marini, Annalisa Costale, Gianluca Miglio, Matteo Fornai, Luca Antonioli, Gloria López-Castejón,[...]. J Med Chem 2017
84
19

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
639
16

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling.
Joseph A Duncan, Daniel T Bergstralh, Yanhong Wang, Stephen B Willingham, Zhengmao Ye, Albert G Zimmermann, Jenny Pan-Yun Ting. Proc Natl Acad Sci U S A 2007
300
15

Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.
Humayun Sharif, Li Wang, Wei Li Wang, Venkat Giri Magupalli, Liudmila Andreeva, Qi Qiao, Arthur V Hauenstein, Zhaolong Wu, Gabriel Núñez, Youdong Mao,[...]. Nature 2019
200
15

The inflammasome NLRs in immunity, inflammation, and associated diseases.
Beckley K Davis, Haitao Wen, Jenny P-Y Ting. Annu Rev Immunol 2011
14

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.
Michael J D Daniels, Jack Rivers-Auty, Tom Schilling, Nicholas G Spencer, William Watremez, Victoria Fasolino, Sophie J Booth, Claire S White, Alex G Baldwin, Sally Freeman,[...]. Nat Commun 2016
208
14

Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
Bénédicte F Py, Mi-Sung Kim, Helin Vakifahmetoglu-Norberg, Junying Yuan. Mol Cell 2013
395
14

CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation.
Tiantian Tang, Xueting Lang, Congfei Xu, Xiaqiong Wang, Tao Gong, Yanqing Yang, Jun Cui, Li Bai, Jun Wang, Wei Jiang,[...]. Nat Commun 2017
129
14

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Hexin Shi, Ying Wang, Xiaohong Li, Xiaoming Zhan, Miao Tang, Maggy Fina, Lijing Su, David Pratt, Chun Hui Bu, Sara Hildebrand,[...]. Nat Immunol 2016
338
14

MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice.
Agampodi Promoda Perera, Ruchira Fernando, Tanvi Shinde, Rohit Gundamaraju, Benjamin Southam, Sukhwinder Singh Sohal, Avril A B Robertson, Kate Schroder, Dale Kunde, Rajaraman Eri. Sci Rep 2018
128
14

Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial.
Viola Klück, Tim L Th A Jansen, Matthijs Janssen, Antoaneta Comarniceanu, Monique Efdé, Isak W Tengesdal, Kiki Schraa, Maartje C P Cleophas, Curtis L Scribner, Damaris B Skouras,[...]. Lancet Rheumatol 2020
52
26

Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
14

Critical role for calcium mobilization in activation of the NLRP3 inflammasome.
Tomohiko Murakami, Johan Ockinger, Jiujiu Yu, Vanessa Byles, Aisleen McColl, Aldebaran M Hofer, Tiffany Horng. Proc Natl Acad Sci U S A 2012
474
14

Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
13

Molecular mechanisms regulating NLRP3 inflammasome activation.
Eun-Kyeong Jo, Jin Kyung Kim, Dong-Min Shin, Chihiro Sasakawa. Cell Mol Immunol 2016
619
13

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Christian Bauer, Peter Duewell, Christine Mayer, Hans Anton Lehr, Katherine A Fitzgerald, Marc Dauer, Jurg Tschopp, Stefan Endres, Eicke Latz, Max Schnurr. Gut 2010
468
13

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance.
Bolormaa Vandanmagsar, Yun-Hee Youm, Anthony Ravussin, Jose E Galgani, Krisztian Stadler, Randall L Mynatt, Eric Ravussin, Jacqueline M Stephens, Vishwa Deep Dixit. Nat Med 2011
13

NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation.
Nan Song, Zhao-Shan Liu, Wen Xue, Zhao-Fang Bai, Qian-Yi Wang, Jiang Dai, Xin Liu, Yi-Jiao Huang, Hong Cai, Xiao-Yan Zhan,[...]. Mol Cell 2017
202
13

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
13

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.
Auvro R Mridha, Alexander Wree, Avril A B Robertson, Matthew M Yeh, Casey D Johnson, Derrick M Van Rooyen, Fahrettin Haczeyni, Narci C-H Teoh, Christopher Savard, George N Ioannou,[...]. J Hepatol 2017
407
12

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.
Haitao Wen, Denis Gris, Yu Lei, Sushmita Jha, Lu Zhang, Max Tze-Han Huang, Willie June Brickey, Jenny P-Y Ting. Nat Immunol 2011
12



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.