A citation-based method for searching scientific literature

Sung Hee Choi, Eric Severson, Warren S Pear, Xiaole S Liu, Jon C Aster, Stephen C Blacklow. PLoS One 2017
Times Cited: 18







List of co-cited articles
199 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
P Bernasconi-Elias, T Hu, D Jenkins, B Firestone, S Gans, E Kurth, P Capodieci, J Deplazes-Lauber, K Petropoulos, P Thiel,[...]. Oncogene 2016
49
55

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
55

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
67
33

Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
V Agnusdei, S Minuzzo, C Frasson, A Grassi, F Axelrod, S Satyal, A Gurney, T Hoey, E Seganfreddo, G Basso,[...]. Leukemia 2014
80
33

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Birgit Knoechel, Justine E Roderick, Kaylyn E Williamson, Jiang Zhu, Jens G Lohr, Matthew J Cotton, Shawn M Gillespie, Daniel Fernandez, Manching Ku, Hongfang Wang,[...]. Nat Genet 2014
232
33

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.
Diana Bellavia, Antonio F Campese, Saula Checquolo, Anna Balestri, Andrea Biondi, Giovanni Cazzaniga, Urban Lendahl, Hans J Fehling, Adrian C Hayday, Luigi Frati,[...]. Proc Natl Acad Sci U S A 2002
159
33

Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
555
27

Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
508
27

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
484
27

The Varied Roles of Notch in Cancer.
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
253
27

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.
Alessandra Vacca, Maria Pia Felli, Rocco Palermo, Giuseppina Di Mario, Angelica Calce, Monica Di Giovine, Luigi Frati, Alberto Gulino, Isabella Screpanti. EMBO J 2006
113
27

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
648
27

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
581
27

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
27

Evaluation of selective gamma-secretase inhibitor PF-03084014 for its antitumor efficacy and gastrointestinal safety to guide optimal clinical trial design.
Ping Wei, Marlena Walls, Ming Qiu, Richard Ding, Robert H Denlinger, Anthony Wong, Kosta Tsaparikos, Jitesh P Jani, Natilie Hosea, Michelle Sands,[...]. Mol Cancer Ther 2010
139
27


Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia.
Jeremy B Samon, Mireia Castillo-Martin, Michael Hadler, Alberto Ambesi-Impiobato, Elisabeth Paietta, Janis Racevskis, Peter H Wiernik, Jacob M Rowe, John Jakubczak, Sophia Randolph,[...]. Mol Cancer Ther 2012
80
22

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.
Nicholas J Wang, Zachary Sanborn, Kelly L Arnett, Laura J Bayston, Wilson Liao, Charlotte M Proby, Irene M Leigh, Eric A Collisson, Patricia B Gordon, Lakshmi Jakkula,[...]. Proc Natl Acad Sci U S A 2011
305
22

Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.
Yumi Yashiro-Ohtani, Hongfang Wang, Chongzhi Zang, Kelly L Arnett, Will Bailis, Yugong Ho, Birgit Knoechel, Claudia Lanauze, Lumena Louis, Katherine S Forsyth,[...]. Proc Natl Acad Sci U S A 2014
110
22

Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Belinda Cancilla, William R Henner, Rene Meisner, Aaron Sato, Jalpa Shah,[...]. Clin Cancer Res 2015
158
22

Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.
Giovanni Roti, Anne Carlton, Kenneth N Ross, Michele Markstein, Kostandin Pajcini, Angela H Su, Norbert Perrimon, Warren S Pear, Andrew L Kung, Stephen C Blacklow,[...]. Cancer Cell 2013
91
22

Synergistic antileukemic therapies in NOTCH1-induced T-ALL.
Marta Sanchez-Martin, Alberto Ambesi-Impiombato, Yue Qin, Daniel Herranz, Mukesh Bansal, Tiziana Girardi, Elisabeth Paietta, Martin S Tallman, Jacob M Rowe, Kim De Keersmaecker,[...]. Proc Natl Acad Sci U S A 2017
37
22

Acetylation controls Notch3 stability and function in T-cell leukemia.
R Palermo, S Checquolo, A Giovenco, P Grazioli, V Kumar, A F Campese, A Giorgi, M Napolitano, G Canettieri, G Ferrara,[...]. Oncogene 2012
41
22

γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.
Yong Ran, Fokhrul Hossain, Antonio Pannuti, Christian B Lessard, Gabriela Z Ladd, Joo In Jung, Lisa M Minter, Barbara A Osborne, Lucio Miele, Todd E Golde. EMBO Mol Med 2017
72
22

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice.
D Bellavia, A F Campese, E Alesse, A Vacca, M P Felli, A Balestri, A Stoppacciaro, C Tiveron, L Tatangelo, M Giovarelli,[...]. EMBO J 2000
297
22

Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia.
V Kumar, R Palermo, C Talora, A F Campese, S Checquolo, D Bellavia, L Tottone, G Testa, E Miele, S Indraccolo,[...]. Leukemia 2014
118
22


NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.
Hongfang Wang, Chongzhi Zang, Len Taing, Kelly L Arnett, Yinling Joey Wong, Warren S Pear, Stephen C Blacklow, X Shirley Liu, Jon C Aster. Proc Natl Acad Sci U S A 2014
143
22

Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.
G Franciosa, G Diluvio, F Del Gaudio, M V Giuli, R Palermo, P Grazioli, A F Campese, C Talora, D Bellavia, G D'Amati,[...]. Oncogene 2016
37
22

Targeting the Notch1 and mTOR pathways in a mouse T-ALL model.
Kathleen Cullion, Kyle M Draheim, Nicole Hermance, Jennifer Tammam, Vishva M Sharma, Christopher Ware, George Nikov, Veena Krishnamoorthy, Pradip K Majumder, Michelle A Kelliher. Blood 2009
105
22

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
316
22

Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
Tomas Vilimas, Joaquina Mascarenhas, Teresa Palomero, Malay Mandal, Silvia Buonamici, Fanyong Meng, Benjamín Thompson, Christina Spaulding, Sami Macaroun, Maria-Luisa Alegre,[...]. Nat Med 2007
247
22

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
Miguel Aste-Amézaga, Ningyan Zhang, Janet E Lineberger, Beth A Arnold, Timothy J Toner, Mingcheng Gu, Lingyi Huang, Salvatore Vitelli, Kim T Vo, Peter Haytko,[...]. PLoS One 2010
128
22

Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
Sudhir S Rao, Jennifer O'Neil, Cole D Liberator, James S Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E Kohl, Victoria M Richon,[...]. Cancer Res 2009
107
22



Notch signaling as a therapeutic target for acute lymphoblastic leukemia.
Diana Bellavia, Rocco Palermo, Maria Pia Felli, Isabella Screpanti, Saula Checquolo. Expert Opin Ther Targets 2018
23
22

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.
Joseph Milano, Jenny McKay, Claude Dagenais, Linda Foster-Brown, Francois Pognan, Reto Gadient, Robert T Jacobs, Anna Zacco, Barry Greenberg, Paul J Ciaccio. Toxicol Sci 2004
408
22

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke, David Nittner, Rajeshwar Narlawar, Sofie Demeyer, James Dooley, Adrian Liston,[...]. Sci Transl Med 2019
42
22

Constitutive NOTCH3 Signaling Promotes the Growth of Basal Breast Cancers.
Lisa Choy, Thijs J Hagenbeek, Margaret Solon, Dorothy French, David Finkle, Amy Shelton, Rayna Venook, Matthew J Brauer, Christian W Siebel. Cancer Res 2017
50
16

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
612
16

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
16

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.
Panagiotis Ntziachristos, Aristotelis Tsirigos, Pieter Van Vlierberghe, Jelena Nedjic, Thomas Trimarchi, Maria Sol Flaherty, Dolors Ferres-Marco, Vanina da Ros, Zuojian Tang, Jasmin Siegle,[...]. Nat Med 2012
335
16

Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia.
Mattia Mori, Luca Tottone, Deborah Quaglio, Nadezda Zhdanovskaya, Cinzia Ingallina, Marisa Fusto, Francesca Ghirga, Giovanna Peruzzi, Maria Elisa Crestoni, Fabrizio Simeoni,[...]. Sci Rep 2017
28
16

Notch3 and canonical NF-kappaB signaling pathways cooperatively regulate Foxp3 transcription.
Alessandro Barbarulo, Paola Grazioli, Antonio F Campese, Diana Bellavia, Giuseppina Di Mario, Maria Pelullo, Ambra Ciuffetta, Sara Colantoni, Alessandra Vacca, Luigi Frati,[...]. J Immunol 2011
55
16

Epigenetic inactivation of Notch-Hes pathway in human B-cell acute lymphoblastic leukemia.
Shao-Qing Kuang, Zhihong Fang, Patrick A Zweidler-McKay, Hui Yang, Yue Wei, Emilio A Gonzalez-Cervantes, Yanis Boumber, Guillermo Garcia-Manero. PLoS One 2013
36
16

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes.
Michael J Malecki, Cheryll Sanchez-Irizarry, Jennifer L Mitchell, Gavin Histen, Mina L Xu, Jon C Aster, Stephen C Blacklow. Mol Cell Biol 2006
183
16

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.
Panagiotis Ntziachristos, Aristotelis Tsirigos, G Grant Welstead, Thomas Trimarchi, Sofia Bakogianni, Luyao Xu, Evangelia Loizou, Linda Holmfeldt, Alexandros Strikoudis, Bryan King,[...]. Nature 2014
242
16

The epigenetic factor BORIS/CTCFL regulates the NOTCH3 gene expression in cancer cells.
Michele Zampieri, Fabio Ciccarone, Rocco Palermo, Samantha Cialfi, Claudio Passananti, Sabina Chiaretti, Daniela Nocchia, Claudio Talora, Isabella Screpanti, Paola Caiafa. Biochim Biophys Acta 2014
20
16

Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL.
Maria Pelullo, Roberta Quaranta, Claudio Talora, Saula Checquolo, Samantha Cialfi, Maria Pia Felli, Geertruy te Kronnie, Chiara Borga, Zein Mersini Besharat, Rocco Palermo,[...]. Neoplasia 2014
33
16


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.