Jang-Hyun Oh, Shun-Jia Chen, Alexander Varshavsky. J Biol Chem 2017
Times Cited: 12
Times Cited: 12
Times Cited
Times Co-cited
Similarity
An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes.
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
100
Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Cheng Dong, Heng Zhang, Li Li, Wolfram Tempel, Peter Loppnau, Jinrong Min. Nat Chem Biol 2018
Cheng Dong, Heng Zhang, Li Li, Wolfram Tempel, Peter Loppnau, Jinrong Min. Nat Chem Biol 2018
83
Gid10 as an alternative N-recognin of the Pro/N-degron pathway.
Artem Melnykov, Shun-Jia Chen, Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
Artem Melnykov, Shun-Jia Chen, Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
83
75
Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways.
Jochen Regelmann, Thomas Schüle, Frank S Josupeit, Jaroslav Horak, Matthias Rose, Karl-Dieter Entian, Michael Thumm, Dieter H Wolf. Mol Biol Cell 2003
Jochen Regelmann, Thomas Schüle, Frank S Josupeit, Jaroslav Horak, Matthias Rose, Karl-Dieter Entian, Michael Thumm, Dieter H Wolf. Mol Biol Cell 2003
66
Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway.
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
Anna Shemorry, Cheol-Sang Hwang, Alexander Varshavsky. Mol Cell 2013
66
The yeast GID complex, a novel ubiquitin ligase (E3) involved in the regulation of carbohydrate metabolism.
Olivier Santt, Thorsten Pfirrmann, Bernhard Braun, Jeannette Juretschke, Philipp Kimmig, Hartmut Scheel, Kay Hofmann, Michael Thumm, Dieter H Wolf. Mol Biol Cell 2008
Olivier Santt, Thorsten Pfirrmann, Bernhard Braun, Jeannette Juretschke, Philipp Kimmig, Hartmut Scheel, Kay Hofmann, Michael Thumm, Dieter H Wolf. Mol Biol Cell 2008
66
N-degron and C-degron pathways of protein degradation.
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
66
In vivo half-life of a protein is a function of its amino-terminal residue.
A Bachmair, D Finley, A Varshavsky. Science 1986
A Bachmair, D Finley, A Varshavsky. Science 1986
58
The Gid-complex: an emerging player in the ubiquitin ligase league.
Huaize Liu, Thorsten Pfirrmann. Biol Chem 2019
Huaize Liu, Thorsten Pfirrmann. Biol Chem 2019
58
The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.
Fabienne Lampert, Diana Stafa, Algera Goga, Martin Varis Soste, Samuel Gilberto, Natacha Olieric, Paola Picotti, Markus Stoffel, Matthias Peter. Elife 2018
Fabienne Lampert, Diana Stafa, Algera Goga, Martin Varis Soste, Samuel Gilberto, Natacha Olieric, Paola Picotti, Markus Stoffel, Matthias Peter. Elife 2018
58
Exploring the topology of the Gid complex, the E3 ubiquitin ligase involved in catabolite-induced degradation of gluconeogenic enzymes.
Ruth Menssen, Jörg Schweiggert, Jens Schreiner, Denis Kusevic, Julia Reuther, Bernhard Braun, Dieter H Wolf. J Biol Chem 2012
Ruth Menssen, Jörg Schweiggert, Jens Schreiner, Denis Kusevic, Julia Reuther, Bernhard Braun, Dieter H Wolf. J Biol Chem 2012
58
The N-end rule pathway.
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
58
Regulation of the Gid ubiquitin ligase recognition subunit Gid4.
Ruth Menssen, Kim Bui, Dieter H Wolf. FEBS Lett 2018
Ruth Menssen, Kim Bui, Dieter H Wolf. FEBS Lett 2018
58
Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly.
Shuai Qiao, Christine R Langlois, Jakub Chrustowicz, Dawafuti Sherpa, Ozge Karayel, Fynn M Hansen, Viola Beier, Susanne von Gronau, Daniel Bollschweiler, Tillman Schäfer,[...]. Mol Cell 2020
Shuai Qiao, Christine R Langlois, Jakub Chrustowicz, Dawafuti Sherpa, Ozge Karayel, Fynn M Hansen, Viola Beier, Susanne von Gronau, Daniel Bollschweiler, Tillman Schäfer,[...]. Mol Cell 2020
58
Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway.
Konstantin I Piatkov, Jang-Hyun Oh, Yuan Liu, Alexander Varshavsky. Proc Natl Acad Sci U S A 2014
Konstantin I Piatkov, Jang-Hyun Oh, Yuan Liu, Alexander Varshavsky. Proc Natl Acad Sci U S A 2014
50
Gid9, a second RING finger protein contributes to the ubiquitin ligase activity of the Gid complex required for catabolite degradation.
Bernhard Braun, Thorsten Pfirrmann, Ruth Menssen, Kay Hofmann, Hartmut Scheel, Dieter H Wolf. FEBS Lett 2011
Bernhard Braun, Thorsten Pfirrmann, Ruth Menssen, Kay Hofmann, Hartmut Scheel, Dieter H Wolf. FEBS Lett 2011
50
Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
50
Ubiquitin Ligases: Structure, Function, and Regulation.
Ning Zheng, Nitzan Shabek. Annu Rev Biochem 2017
Ning Zheng, Nitzan Shabek. Annu Rev Biochem 2017
50
The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments.
Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Proc Natl Acad Sci U S A 2012
Konstantin I Piatkov, Christopher S Brower, Alexander Varshavsky. Proc Natl Acad Sci U S A 2012
50
N-terminal acetylation of cellular proteins creates specific degradation signals.
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
50
Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases.
Vinayak Vittal, Mikaela D Stewart, Peter S Brzovic, Rachel E Klevit. J Biol Chem 2015
Vinayak Vittal, Mikaela D Stewart, Peter S Brzovic, Rachel E Klevit. J Biol Chem 2015
50
Proteins of newly isolated mutants and the amino-terminal proline are essential for ubiquitin-proteasome-catalyzed catabolite degradation of fructose-1,6-bisphosphatase of Saccharomyces cerevisiae.
M Hämmerle, J Bauer, M Rose, A Szallies, M Thumm, S Düsterhus, D Mecke, K D Entian, D H Wolf. J Biol Chem 1998
M Hämmerle, J Bauer, M Rose, A Szallies, M Thumm, S Düsterhus, D Mecke, K D Entian, D H Wolf. J Biol Chem 1998
50
Crosstalk and Interplay between the Ubiquitin-Proteasome System and Autophagy.
Chang Hoon Ji, Yong Tae Kwon. Mol Cells 2017
Chang Hoon Ji, Yong Tae Kwon. Mol Cells 2017
41
The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.
Konstantin I Piatkov, Luca Colnaghi, Miklos Békés, Alexander Varshavsky, Tony T Huang. Mol Cell 2012
Konstantin I Piatkov, Luca Colnaghi, Miklos Békés, Alexander Varshavsky, Tony T Huang. Mol Cell 2012
41
The N-end rule pathway: from recognition by N-recognins, to destruction by AAA+proteases.
D A Dougan, D Micevski, K N Truscott. Biochim Biophys Acta 2012
D A Dougan, D Micevski, K N Truscott. Biochim Biophys Acta 2012
41
Basic Medical Research Award. The ubiquitin system.
A Hershko, A Ciechanover, A Varshavsky. Nat Med 2000
A Hershko, A Ciechanover, A Varshavsky. Nat Med 2000
41
RMND5 from Xenopus laevis is an E3 ubiquitin-ligase and functions in early embryonic forebrain development.
Thorsten Pfirrmann, Pablo Villavicencio-Lorini, Abinash K Subudhi, Ruth Menssen, Dieter H Wolf, Thomas Hollemann. PLoS One 2015
Thorsten Pfirrmann, Pablo Villavicencio-Lorini, Abinash K Subudhi, Ruth Menssen, Dieter H Wolf, Thomas Hollemann. PLoS One 2015
41
Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability.
H Rao, F Uhlmann, K Nasmyth, A Varshavsky. Nature 2001
H Rao, F Uhlmann, K Nasmyth, A Varshavsky. Nature 2001
41
Molecular phylogeny of a RING E3 ubiquitin ligase, conserved in eukaryotic cells and dominated by homologous components, the muskelin/RanBPM/CTLH complex.
Ore Francis, Fujun Han, Josephine C Adams. PLoS One 2013
Ore Francis, Fujun Han, Josephine C Adams. PLoS One 2013
41
First Things First: Vital Protein Marks by N-Terminal Acetyltransferases.
Henriette Aksnes, Adrian Drazic, Michaël Marie, Thomas Arnesen. Trends Biochem Sci 2016
Henriette Aksnes, Adrian Drazic, Michaël Marie, Thomas Arnesen. Trends Biochem Sci 2016
41
Defining the geometry of the two-component proteasome degron.
Tomonao Inobe, Susan Fishbain, Sumit Prakash, Andreas Matouschek. Nat Chem Biol 2011
Tomonao Inobe, Susan Fishbain, Sumit Prakash, Andreas Matouschek. Nat Chem Biol 2011
41
Formyl-methionine as an N-degron of a eukaryotic N-end rule pathway.
Jeong-Mok Kim, Ok-Hee Seok, Shinyeong Ju, Ji-Eun Heo, Jeonghun Yeom, Da-Som Kim, Joo-Yeon Yoo, Alexander Varshavsky, Cheolju Lee, Cheol-Sang Hwang. Science 2018
Jeong-Mok Kim, Ok-Hee Seok, Shinyeong Ju, Ji-Eun Heo, Jeonghun Yeom, Da-Som Kim, Joo-Yeon Yoo, Alexander Varshavsky, Cheolju Lee, Cheol-Sang Hwang. Science 2018
41
Control of Hsp90 chaperone and its clients by N-terminal acetylation and the N-end rule pathway.
Jang-Hyun Oh, Ju-Yeon Hyun, Alexander Varshavsky. Proc Natl Acad Sci U S A 2017
Jang-Hyun Oh, Ju-Yeon Hyun, Alexander Varshavsky. Proc Natl Acad Sci U S A 2017
41
RanBPM, Muskelin, p48EMLP, p44CTLH, and the armadillo-repeat proteins ARMC8alpha and ARMC8beta are components of the CTLH complex.
Nobuaki Kobayashi, Jun Yang, Atsuhisa Ueda, Takeyuki Suzuki, Kouji Tomaru, Mitsuhiro Takeno, Kenji Okuda, Yoshiaki Ishigatsubo. Gene 2007
Nobuaki Kobayashi, Jun Yang, Atsuhisa Ueda, Takeyuki Suzuki, Kouji Tomaru, Mitsuhiro Takeno, Kenji Okuda, Yoshiaki Ishigatsubo. Gene 2007
41
The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions.
Daniel J Gibbs, Jaume Bacardit, Andreas Bachmair, Michael J Holdsworth. Trends Cell Biol 2014
Daniel J Gibbs, Jaume Bacardit, Andreas Bachmair, Michael J Holdsworth. Trends Cell Biol 2014
41
In vivo aspects of protein folding and quality control.
David Balchin, Manajit Hayer-Hartl, F Ulrich Hartl. Science 2016
David Balchin, Manajit Hayer-Hartl, F Ulrich Hartl. Science 2016
41
Structure and Function of the 26S Proteasome.
Jared A M Bard, Ellen A Goodall, Eric R Greene, Erik Jonsson, Ken C Dong, Andreas Martin. Annu Rev Biochem 2018
Jared A M Bard, Ellen A Goodall, Eric R Greene, Erik Jonsson, Ken C Dong, Andreas Martin. Annu Rev Biochem 2018
41
Structure of the human 26S proteasome at a resolution of 3.9 Å.
Andreas Schweitzer, Antje Aufderheide, Till Rudack, Florian Beck, Günter Pfeifer, Jürgen M Plitzko, Eri Sakata, Klaus Schulten, Friedrich Förster, Wolfgang Baumeister. Proc Natl Acad Sci U S A 2016
Andreas Schweitzer, Antje Aufderheide, Till Rudack, Florian Beck, Günter Pfeifer, Jürgen M Plitzko, Eri Sakata, Klaus Schulten, Friedrich Förster, Wolfgang Baumeister. Proc Natl Acad Sci U S A 2016
41
The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Daniel Finley, Helle D Ulrich, Thomas Sommer, Peter Kaiser. Genetics 2012
Daniel Finley, Helle D Ulrich, Thomas Sommer, Peter Kaiser. Genetics 2012
41
Understanding the Pro/N-end rule pathway.
David A Dougan, Alexander Varshavsky. Nat Chem Biol 2018
David A Dougan, Alexander Varshavsky. Nat Chem Biol 2018
41
Recognition of Client Proteins by the Proteasome.
Houqing Yu, Andreas Matouschek. Annu Rev Biophys 2017
Houqing Yu, Andreas Matouschek. Annu Rev Biophys 2017
41
Proteasome Structure and Assembly.
Lauren Budenholzer, Chin Leng Cheng, Yanjie Li, Mark Hochstrasser. J Mol Biol 2017
Lauren Budenholzer, Chin Leng Cheng, Yanjie Li, Mark Hochstrasser. J Mol Biol 2017
41
Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division.
Edmond R Watson, Nicholas G Brown, Jan-Michael Peters, Holger Stark, Brenda A Schulman. Trends Cell Biol 2019
Edmond R Watson, Nicholas G Brown, Jan-Michael Peters, Holger Stark, Brenda A Schulman. Trends Cell Biol 2019
41
Features and development of Coot.
P Emsley, B Lohkamp, W G Scott, K Cowtan. Acta Crystallogr D Biol Crystallogr 2010
P Emsley, B Lohkamp, W G Scott, K Cowtan. Acta Crystallogr D Biol Crystallogr 2010
41
The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators.
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T Takahashi, Alexander Varshavsky. Nature 2005
Rong-Gui Hu, Jun Sheng, Xin Qi, Zhenming Xu, Terry T Takahashi, Alexander Varshavsky. Nature 2005
33
33
The N-terminal methionine of cellular proteins as a degradation signal.
Heon-Ki Kim, Ryu-Ryun Kim, Jang-Hyun Oh, Hanna Cho, Alexander Varshavsky, Cheol-Sang Hwang. Cell 2014
Heon-Ki Kim, Ryu-Ryun Kim, Jang-Hyun Oh, Hanna Cho, Alexander Varshavsky, Cheol-Sang Hwang. Cell 2014
33
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.