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Times Cited: 1380
Times Cited: 1380
Times Cited
Times Co-cited
Similarity
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
77
Search-and-replace genome editing without double-strand breaks or donor DNA.
Andrew V Anzalone, Peyton B Randolph, Jessie R Davis, Alexander A Sousa, Luke W Koblan, Jonathan M Levy, Peter J Chen, Christopher Wilson, Gregory A Newby, Aditya Raguram,[...]. Nature 2019
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A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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Multiplex genome engineering using CRISPR/Cas systems.
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
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Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors.
Andrew V Anzalone, Luke W Koblan, David R Liu. Nat Biotechnol 2020
Andrew V Anzalone, Luke W Koblan, David R Liu. Nat Biotechnol 2020
26
Base editing: precision chemistry on the genome and transcriptome of living cells.
Holly A Rees, David R Liu. Nat Rev Genet 2018
Holly A Rees, David R Liu. Nat Rev Genet 2018
24
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems.
Keiji Nishida, Takayuki Arazoe, Nozomu Yachie, Satomi Banno, Mika Kakimoto, Mayura Tabata, Masao Mochizuki, Aya Miyabe, Michihiro Araki, Kiyotaka Y Hara,[...]. Science 2016
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Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity.
Michelle F Richter, Kevin T Zhao, Elliot Eton, Audrone Lapinaite, Gregory A Newby, Benjamin W Thuronyi, Christopher Wilson, Luke W Koblan, Jing Zeng, Daniel E Bauer,[...]. Nat Biotechnol 2020
Michelle F Richter, Kevin T Zhao, Elliot Eton, Audrone Lapinaite, Gregory A Newby, Benjamin W Thuronyi, Christopher Wilson, Luke W Koblan, Jing Zeng, Daniel E Bauer,[...]. Nat Biotechnol 2020
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RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
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Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.
Luke W Koblan, Jordan L Doman, Christopher Wilson, Jonathan M Levy, Tristan Tay, Gregory A Newby, Juan Pablo Maianti, Aditya Raguram, David R Liu. Nat Biotechnol 2018
Luke W Koblan, Jordan L Doman, Christopher Wilson, Jonathan M Levy, Tristan Tay, Gregory A Newby, Juan Pablo Maianti, Aditya Raguram, David R Liu. Nat Biotechnol 2018
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Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements.
Michael Kosicki, Kärt Tomberg, Allan Bradley. Nat Biotechnol 2018
Michael Kosicki, Kärt Tomberg, Allan Bradley. Nat Biotechnol 2018
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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
Johnny H Hu, Shannon M Miller, Maarten H Geurts, Weixin Tang, Liwei Chen, Ning Sun, Christina M Zeina, Xue Gao, Holly A Rees, Zhi Lin,[...]. Nature 2018
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In vivo genome editing using Staphylococcus aureus Cas9.
F Ann Ran, Le Cong, Winston X Yan, David A Scott, Jonathan S Gootenberg, Andrea J Kriz, Bernd Zetsche, Ophir Shalem, Xuebing Wu, Kira S Makarova,[...]. Nature 2015
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Directed evolution of adenine base editors with increased activity and therapeutic application.
Nicole M Gaudelli, Dieter K Lam, Holly A Rees, Noris M Solá-Esteves, Luis A Barrera, David A Born, Aaron Edwards, Jason M Gehrke, Seung-Joo Lee, Alexander J Liquori,[...]. Nat Biotechnol 2020
Nicole M Gaudelli, Dieter K Lam, Holly A Rees, Noris M Solá-Esteves, Luis A Barrera, David A Born, Aaron Edwards, Jason M Gehrke, Seung-Joo Lee, Alexander J Liquori,[...]. Nat Biotechnol 2020
17
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
Bernd Zetsche, Jonathan S Gootenberg, Omar O Abudayyeh, Ian M Slaymaker, Kira S Makarova, Patrick Essletzbichler, Sara E Volz, Julia Joung, John van der Oost, Aviv Regev,[...]. Cell 2015
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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
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Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos.
Erwei Zuo, Yidi Sun, Wu Wei, Tanglong Yuan, Wenqin Ying, Hao Sun, Liyun Yuan, Lars M Steinmetz, Yixue Li, Hui Yang. Science 2019
Erwei Zuo, Yidi Sun, Wu Wei, Tanglong Yuan, Wenqin Ying, Hao Sun, Liyun Yuan, Lars M Steinmetz, Yixue Li, Hui Yang. Science 2019
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CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells.
Ibrahim C Kurt, Ronghao Zhou, Sowmya Iyer, Sara P Garcia, Bret R Miller, Lukas M Langner, Julian Grünewald, J Keith Joung. Nat Biotechnol 2021
Ibrahim C Kurt, Ronghao Zhou, Sowmya Iyer, Sara P Garcia, Bret R Miller, Lukas M Langner, Julian Grünewald, J Keith Joung. Nat Biotechnol 2021
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Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions.
Y Bill Kim, Alexis C Komor, Jonathan M Levy, Michael S Packer, Kevin T Zhao, David R Liu. Nat Biotechnol 2017
Y Bill Kim, Alexis C Komor, Jonathan M Levy, Michael S Packer, Kevin T Zhao, David R Liu. Nat Biotechnol 2017
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Glycosylase base editors enable C-to-A and C-to-G base changes.
Dongdong Zhao, Ju Li, Siwei Li, Xiuqing Xin, Muzi Hu, Marcus A Price, Susan J Rosser, Changhao Bi, Xueli Zhang. Nat Biotechnol 2021
Dongdong Zhao, Ju Li, Siwei Li, Xiuqing Xin, Muzi Hu, Marcus A Price, Susan J Rosser, Changhao Bi, Xueli Zhang. Nat Biotechnol 2021
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Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.
Alexis C Komor, Kevin T Zhao, Michael S Packer, Nicole M Gaudelli, Amanda L Waterbury, Luke W Koblan, Y Bill Kim, Ahmed H Badran, David R Liu. Sci Adv 2017
Alexis C Komor, Kevin T Zhao, Michael S Packer, Nicole M Gaudelli, Amanda L Waterbury, Luke W Koblan, Y Bill Kim, Ahmed H Badran, David R Liu. Sci Adv 2017
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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.
Luke A Gilbert, Max A Horlbeck, Britt Adamson, Jacqueline E Villalta, Yuwen Chen, Evan H Whitehead, Carla Guimaraes, Barbara Panning, Hidde L Ploegh, Michael C Bassik,[...]. Cell 2014
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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.
Luke A Gilbert, Matthew H Larson, Leonardo Morsut, Zairan Liu, Gloria A Brar, Sandra E Torres, Noam Stern-Ginossar, Onn Brandman, Evan H Whitehead, Jennifer A Doudna,[...]. Cell 2013
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DNA targeting specificity of RNA-guided Cas9 nucleases.
Patrick D Hsu, David A Scott, Joshua A Weinstein, F Ann Ran, Silvana Konermann, Vineeta Agarwala, Yinqing Li, Eli J Fine, Xuebing Wu, Ophir Shalem,[...]. Nat Biotechnol 2013
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Rationally engineered Cas9 nucleases with improved specificity.
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
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CRISPR DNA base editors with reduced RNA off-target and self-editing activities.
Julian Grünewald, Ronghao Zhou, Sowmya Iyer, Caleb A Lareau, Sara P Garcia, Martin J Aryee, J Keith Joung. Nat Biotechnol 2019
Julian Grünewald, Ronghao Zhou, Sowmya Iyer, Caleb A Lareau, Sara P Garcia, Martin J Aryee, J Keith Joung. Nat Biotechnol 2019
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Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis.
Changyang Zhou, Yidi Sun, Rui Yan, Yajing Liu, Erwei Zuo, Chan Gu, Linxiao Han, Yu Wei, Xinde Hu, Rong Zeng,[...]. Nature 2019
Changyang Zhou, Yidi Sun, Rui Yan, Yajing Liu, Erwei Zuo, Chan Gu, Linxiao Han, Yu Wei, Xinde Hu, Rong Zeng,[...]. Nature 2019
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Engineered CRISPR-Cas9 nuclease with expanded targeting space.
Hiroshi Nishimasu, Xi Shi, Soh Ishiguro, Linyi Gao, Seiichi Hirano, Sae Okazaki, Taichi Noda, Omar O Abudayyeh, Jonathan S Gootenberg, Hideto Mori,[...]. Science 2018
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Enhanced prime editing systems by manipulating cellular determinants of editing outcomes.
Peter J Chen, Jeffrey A Hussmann, Jun Yan, Friederike Knipping, Purnima Ravisankar, Pin-Fang Chen, Cidi Chen, James W Nelson, Gregory A Newby, Mustafa Sahin,[...]. Cell 2021
Peter J Chen, Jeffrey A Hussmann, Jun Yan, Friederike Knipping, Purnima Ravisankar, Pin-Fang Chen, Cidi Chen, James W Nelson, Gregory A Newby, Mustafa Sahin,[...]. Cell 2021
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Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants.
Russell T Walton, Kathleen A Christie, Madelynn N Whittaker, Benjamin P Kleinstiver. Science 2020
Russell T Walton, Kathleen A Christie, Madelynn N Whittaker, Benjamin P Kleinstiver. Science 2020
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Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.
Janice S Chen, Yavuz S Dagdas, Benjamin P Kleinstiver, Moira M Welch, Alexander A Sousa, Lucas B Harrington, Samuel H Sternberg, J Keith Joung, Ahmet Yildiz, Jennifer A Doudna. Nature 2017
Janice S Chen, Yavuz S Dagdas, Benjamin P Kleinstiver, Moira M Welch, Alexander A Sousa, Lucas B Harrington, Samuel H Sternberg, J Keith Joung, Ahmet Yildiz, Jennifer A Doudna. Nature 2017
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Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Benjamin P Kleinstiver, Michelle S Prew, Shengdar Q Tsai, Ved V Topkar, Nhu T Nguyen, Zongli Zheng, Andrew P W Gonzales, Zhuyun Li, Randall T Peterson, Jing-Ruey Joanna Yeh,[...]. Nature 2015
Benjamin P Kleinstiver, Michelle S Prew, Shengdar Q Tsai, Ved V Topkar, Nhu T Nguyen, Zongli Zheng, Andrew P W Gonzales, Zhuyun Li, Randall T Peterson, Jing-Ruey Joanna Yeh,[...]. Nature 2015
11
Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion.
Zenpei Shimatani, Sachiko Kashojiya, Mariko Takayama, Rie Terada, Takayuki Arazoe, Hisaki Ishii, Hiroshi Teramura, Tsuyoshi Yamamoto, Hiroki Komatsu, Kenji Miura,[...]. Nat Biotechnol 2017
Zenpei Shimatani, Sachiko Kashojiya, Mariko Takayama, Rie Terada, Takayuki Arazoe, Hisaki Ishii, Hiroshi Teramura, Tsuyoshi Yamamoto, Hiroki Komatsu, Kenji Miura,[...]. Nat Biotechnol 2017
11
Prime genome editing in rice and wheat.
Qiupeng Lin, Yuan Zong, Chenxiao Xue, Shengxing Wang, Shuai Jin, Zixu Zhu, Yanpeng Wang, Andrew V Anzalone, Aditya Raguram, Jordan L Doman,[...]. Nat Biotechnol 2020
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11
In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.
Luke W Koblan, Michael R Erdos, Christopher Wilson, Wayne A Cabral, Jonathan M Levy, Zheng-Mei Xiong, Urraca L Tavarez, Lindsay M Davison, Yantenew G Gete, Xiaojing Mao,[...]. Nature 2021
Luke W Koblan, Michael R Erdos, Christopher Wilson, Wayne A Cabral, Jonathan M Levy, Zheng-Mei Xiong, Urraca L Tavarez, Lindsay M Davison, Yantenew G Gete, Xiaojing Mao,[...]. Nature 2021
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Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice.
Shuai Jin, Yuan Zong, Qiang Gao, Zixu Zhu, Yanpeng Wang, Peng Qin, Chengzhi Liang, Daowen Wang, Jin-Long Qiu, Feng Zhang,[...]. Science 2019
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CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis.
Julian D Gillmore, Ed Gane, Jorg Taubel, Justin Kao, Marianna Fontana, Michael L Maitland, Jessica Seitzer, Daniel O'Connell, Kathryn R Walsh, Kristy Wood,[...]. N Engl J Med 2021
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RNA editing with CRISPR-Cas13.
David B T Cox, Jonathan S Gootenberg, Omar O Abudayyeh, Brian Franklin, Max J Kellner, Julia Joung, Feng Zhang. Science 2017
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CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations.
Cem Kuscu, Mahmut Parlak, Turan Tufan, Jiekun Yang, Karol Szlachta, Xiaolong Wei, Rashad Mammadov, Mazhar Adli. Nat Methods 2017
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CRISPR-engineered T cells in patients with refractory cancer.
Edward A Stadtmauer, Joseph A Fraietta, Megan M Davis, Adam D Cohen, Kristy L Weber, Eric Lancaster, Patricia A Mangan, Irina Kulikovskaya, Minnal Gupta, Fang Chen,[...]. Science 2020
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Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases.
Sangsu Bae, Jeongbin Park, Jin-Soo Kim. Bioinformatics 2014
Sangsu Bae, Jeongbin Park, Jin-Soo Kim. Bioinformatics 2014
10
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors.
Julian Grünewald, Ronghao Zhou, Sara P Garcia, Sowmya Iyer, Caleb A Lareau, Martin J Aryee, J Keith Joung. Nature 2019
Julian Grünewald, Ronghao Zhou, Sara P Garcia, Sowmya Iyer, Caleb A Lareau, Martin J Aryee, J Keith Joung. Nature 2019
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Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells.
Yunqing Ma, Jiayuan Zhang, Weijie Yin, Zhenchao Zhang, Yan Song, Xing Chang. Nat Methods 2016
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Analysis and minimization of cellular RNA editing by DNA adenine base editors.
Holly A Rees, Christopher Wilson, Jordan L Doman, David R Liu. Sci Adv 2019
Holly A Rees, Christopher Wilson, Jordan L Doman, David R Liu. Sci Adv 2019
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An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities.
Jason M Gehrke, Oliver Cervantes, M Kendell Clement, Yuxuan Wu, Jing Zeng, Daniel E Bauer, Luca Pinello, J Keith Joung. Nat Biotechnol 2018
Jason M Gehrke, Oliver Cervantes, M Kendell Clement, Yuxuan Wu, Jing Zeng, Daniel E Bauer, Luca Pinello, J Keith Joung. Nat Biotechnol 2018
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CRISPResso2 provides accurate and rapid genome editing sequence analysis.
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A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing.
Julian Grünewald, Ronghao Zhou, Caleb A Lareau, Sara P Garcia, Sowmya Iyer, Bret R Miller, Lukas M Langner, Jonathan Y Hsu, Martin J Aryee, J Keith Joung. Nat Biotechnol 2020
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Efficient generation of mouse models with the prime editing system.
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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.
Giedrius Gasiunas, Rodolphe Barrangou, Philippe Horvath, Virginijus Siksnys. Proc Natl Acad Sci U S A 2012
Giedrius Gasiunas, Rodolphe Barrangou, Philippe Horvath, Virginijus Siksnys. Proc Natl Acad Sci U S A 2012
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.