A citation-based method for searching scientific literature

Weinan Du, Luchang Zhang, Adina Brett-Morris, Brittany Aguila, Janos Kerner, Charles L Hoppel, Michelle Puchowicz, Dolors Serra, Laura Herrero, Brian I Rini, Steven Campbell, Scott M Welford. Nat Commun 2017
Times Cited: 149







List of co-cited articles
1033 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma.
Bo Qiu, Daniel Ackerman, Danielle J Sanchez, Bo Li, Joshua D Ochocki, Alison Grazioli, Ekaterina Bobrovnikova-Marjon, J Alan Diehl, Brian Keith, M Celeste Simon. Cancer Discov 2015
177
25


An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma.
A Ari Hakimi, Ed Reznik, Chung-Han Lee, Chad J Creighton, A Rose Brannon, Augustin Luna, B Arman Aksoy, Eric Minwei Liu, Ronglai Shen, William Lee,[...]. Cancer Cell 2016
299
19

Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation.
Karim Bensaad, Elena Favaro, Caroline A Lewis, Barrie Peck, Simon Lord, Jennifer M Collins, Katherine E Pinnick, Simon Wigfield, Francesca M Buffa, Ji-Liang Li,[...]. Cell Rep 2014
303
18

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Christian M Metallo, Paulo A Gameiro, Eric L Bell, Katherine R Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M Jewell, Zachary R Johnson, Darrell J Irvine, Leonard Guarente,[...]. Nature 2011
18

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
18

Renal cell carcinoma.
James J Hsieh, Mark P Purdue, Sabina Signoretti, Charles Swanton, Laurence Albiges, Manuela Schmidinger, Daniel Y Heng, James Larkin, Vincenzo Ficarra. Nat Rev Dis Primers 2017
868
17


Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation.
Daniel Ackerman, Sergey Tumanov, Bo Qiu, Evdokia Michalopoulou, Michelle Spata, Andrew Azzam, Hong Xie, M Celeste Simon, Jurre J Kamphorst. Cell Rep 2018
97
15

HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
De Huang, Tingting Li, Xinghua Li, Long Zhang, Linchong Sun, Xiaoping He, Xiuying Zhong, Dongya Jia, Libing Song, Gregg L Semenza,[...]. Cell Rep 2014
190
14

Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis.
Hiromi I Wettersten, A Ari Hakimi, Dexter Morin, Cristina Bianchi, Megan E Johnstone, Dallas R Donohoe, Josephine F Trott, Omran Abu Aboud, Steven Stirdivant, Bruce Neri,[...]. Cancer Res 2015
153
14

Lipid metabolic reprogramming in cancer cells.
S Beloribi-Djefaflia, S Vasseur, F Guillaumond. Oncogenesis 2016
662
14

In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation.
Paulo A Gameiro, Juanjuan Yang, Ana M Metelo, Rocio Pérez-Carro, Rania Baker, Zongwei Wang, Alexandra Arreola, W Kimryn Rathmell, Aria Olumi, Pilar López-Larrubia,[...]. Cell Metab 2013
196
12

Lipidomic Signatures and Associated Transcriptomic Profiles of Clear Cell Renal Cell Carcinoma.
Kosuke Saito, Eri Arai, Keiko Maekawa, Masaki Ishikawa, Hiroyuki Fujimoto, Ryo Taguchi, Kenji Matsumoto, Yae Kanai, Yoshiro Saito. Sci Rep 2016
66
16

Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Andrew R Mullen, William W Wheaton, Eunsook S Jin, Pei-Hsuan Chen, Lucas B Sullivan, Tzuling Cheng, Youfeng Yang, W Marston Linehan, Navdeep S Chandel, Ralph J DeBerardinis. Nature 2011
810
10

Stearoyl-CoA desaturase 1 is a novel molecular therapeutic target for clear cell renal cell carcinoma.
Christina A von Roemeling, Laura A Marlow, Johnny J Wei, Simon J Cooper, Thomas R Caulfield, Kevin Wu, Winston W Tan, Han W Tun, John A Copland. Clin Cancer Res 2013
143
10

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
10

Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo.
Kevin D Courtney, Divya Bezwada, Tomoyuki Mashimo, Kumar Pichumani, Vamsidhara Vemireddy, Alexander M Funk, Jennifer Wimberly, Sarah S McNeil, Payal Kapur, Yair Lotan,[...]. Cell Metab 2018
116
9

Integrated molecular analysis of clear-cell renal cell carcinoma.
Yusuke Sato, Tetsuichi Yoshizato, Yuichi Shiraishi, Shigekatsu Maekawa, Yusuke Okuno, Takumi Kamura, Teppei Shimamura, Aiko Sato-Otsubo, Genta Nagae, Hiromichi Suzuki,[...]. Nat Genet 2013
674
9

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
9

The genetic basis of kidney cancer: a metabolic disease.
W Marston Linehan, Ramaprasad Srinivasan, Laura S Schmidt. Nat Rev Urol 2010
483
9

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption.
Ioanna Papandreou, Rob A Cairns, Lucrezia Fontana, Ai Lin Lim, Nicholas C Denko. Cell Metab 2006
9

Targeting renal cell carcinoma with a HIF-2 antagonist.
Wenfang Chen, Haley Hill, Alana Christie, Min Soo Kim, Eboni Holloman, Andrea Pavia-Jimenez, Farrah Homayoun, Yuanqing Ma, Nirav Patel, Paul Yell,[...]. Nature 2016
364
9

Reprogramming of fatty acid metabolism in cancer.
Nikos Koundouros, George Poulogiannis. Br J Cancer 2020
254
9


Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
P Jaakkola, D R Mole, Y M Tian, M I Wilson, J Gielbert, S J Gaskell, A von Kriegsheim, H F Hebestreit, M Mukherji, C J Schofield,[...]. Science 2001
8

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
G L Wang, B H Jiang, E A Rue, G L Semenza. Proc Natl Acad Sci U S A 1995
8

Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1.
Tina Gimm, Melanie Wiese, Barbara Teschemacher, Anke Deggerich, Johannes Schödel, Karl X Knaup, Thomas Hackenbeck, Claus Hellerbrand, Kerstin Amann, Michael S Wiesener,[...]. FASEB J 2010
94
8

The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma.
Heike Miess, Beatrice Dankworth, Arvin M Gouw, Mathias Rosenfeldt, Werner Schmitz, Ming Jiang, Becky Saunders, Michael Howell, Julian Downward, Dean W Felsher,[...]. Oncogene 2018
105
8

Targeting metastasis-initiating cells through the fatty acid receptor CD36.
Gloria Pascual, Alexandra Avgustinova, Stefania Mejetta, Mercè Martín, Andrés Castellanos, Camille Stephan-Otto Attolini, Antoni Berenguer, Neus Prats, Agustí Toll, Juan Antonio Hueto,[...]. Nature 2017
570
8

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.
Yilong Zou, Michael J Palte, Amy A Deik, Haoxin Li, John K Eaton, Wenyu Wang, Yuen-Yi Tseng, Rebecca Deasy, Maria Kost-Alimova, Vlado Dančík,[...]. Nat Commun 2019
181
8

Cancer metabolism: fatty acid oxidation in the limelight.
Arkaitz Carracedo, Lewis C Cantley, Pier Paolo Pandolfi. Nat Rev Cancer 2013
661
8

The multifaceted roles of fatty acid synthesis in cancer.
Florian Röhrig, Almut Schulze. Nat Rev Cancer 2016
537
8


The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
7

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids.
Jurre J Kamphorst, Justin R Cross, Jing Fan, Elisa de Stanchina, Robin Mathew, Eileen P White, Craig B Thompson, Joshua D Rabinowitz. Proc Natl Acad Sci U S A 2013
412
7

Fatty acid synthase over expression is an indicator of tumor aggressiveness and poor prognosis in renal cell carcinoma.
Akio Horiguchi, Tomohiko Asano, Takako Asano, Keiichi Ito, Makoto Sumitomo, Masamichi Hayakawa. J Urol 2008
81
8

Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers.
Arimichi Okazaki, Paulo A Gameiro, Danos Christodoulou, Laura Laviollette, Meike Schneider, Frances Chaves, Anat Stemmer-Rachamimov, Stephanie A Yazinski, Richard Lee, Gregory Stephanopoulos,[...]. J Clin Invest 2017
51
13


HIF-1α and HIF-2α are critically involved in hypoxia-induced lipid accumulation in hepatocytes through reducing PGC-1α-mediated fatty acid β-oxidation.
Yanlong Liu, Zhenhua Ma, Cuiqing Zhao, Yuhua Wang, Guicheng Wu, Jian Xiao, Craig J McClain, Xiaokun Li, Wenke Feng. Toxicol Lett 2014
70
10

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression.
Brian Keith, Randall S Johnson, M Celeste Simon. Nat Rev Cancer 2011
7

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
7


The mRNA Expression Signature and Prognostic Analysis of Multiple Fatty Acid Metabolic Enzymes in Clear Cell Renal Cell Carcinoma.
Zuohui Zhao, Yueran Liu, Qiang Liu, Fei Wu, Xiaoli Liu, Hongyi Qu, Yijiao Yuan, Juntao Ge, Yue Xu, Hao Wang. J Cancer 2019
17
41

Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.
David R Wise, Patrick S Ward, Jessica E S Shay, Justin R Cross, Joshua J Gruber, Uma M Sachdeva, Jesse M Platt, Raymond G DeMatteo, M Celeste Simon, Craig B Thompson. Proc Natl Acad Sci U S A 2011
656
7

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
6


Abnormal cholesterol metabolism in renal clear cell carcinoma.
R L Gebhard, R V Clayman, W F Prigge, R Figenshau, N A Staley, C Reesey, A Bear. J Lipid Res 1987
106
6

Metabolic reprogramming in clear cell renal cell carcinoma.
Hiromi I Wettersten, Omran Abu Aboud, Primo N Lara, Robert H Weiss. Nat Rev Nephrol 2017
136
6

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development.
Hyun Mi Kang, Seon Ho Ahn, Peter Choi, Yi-An Ko, Seung Hyeok Han, Frank Chinga, Ae Seo Deok Park, Jianling Tao, Kumar Sharma, James Pullman,[...]. Nat Med 2015
605
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.