Marc S Rendell. Expert Opin Pharmacother 2018
Times Cited: 5
Times Cited: 5
Times Cited
Times Co-cited
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Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2.
Chiara Ghezzi, Donald D F Loo, Ernest M Wright. Diabetologia 2018
Chiara Ghezzi, Donald D F Loo, Ernest M Wright. Diabetologia 2018
40
Sotagliflozin: a dual sodium-glucose co-transporter-1 and -2 inhibitor for the management of Type 1 and Type 2 diabetes mellitus.
H Sims, K H Smith, P Bramlage, J Minguet. Diabet Med 2018
H Sims, K H Smith, P Bramlage, J Minguet. Diabet Med 2018
40
Sotagliflozin, the first dual SGLT inhibitor: current outlook and perspectives.
Chiara Maria Assunta Cefalo, Francesca Cinti, Simona Moffa, Flavia Impronta, Gian Pio Sorice, Teresa Mezza, Alfredo Pontecorvi, Andrea Giaccari. Cardiovasc Diabetol 2019
Chiara Maria Assunta Cefalo, Francesca Cinti, Simona Moffa, Flavia Impronta, Gian Pio Sorice, Teresa Mezza, Alfredo Pontecorvi, Andrea Giaccari. Cardiovasc Diabetol 2019
40
Comparative pharmacokinetics of three SGLT-2 inhibitors sergliflozin, remogliflozin and ertugliflozin: an overview.
Ranjeet Prasad Dash, R Jayachandra Babu, Nuggehally R Srinivas. Xenobiotica 2017
Ranjeet Prasad Dash, R Jayachandra Babu, Nuggehally R Srinivas. Xenobiotica 2017
40
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays.
Zhang, Chung, Oldenburg. J Biomol Screen 1999
Zhang, Chung, Oldenburg. J Biomol Screen 1999
20
Identification of Allosteric Modulators of Metabotropic Glutamate 7 Receptor Using Proteochemometric Modeling.
Gary Tresadern, Andres A Trabanco, Laura Pérez-Benito, John P Overington, Herman W T van Vlijmen, Gerard J P van Westen. J Chem Inf Model 2017
Gary Tresadern, Andres A Trabanco, Laura Pérez-Benito, John P Overington, Herman W T van Vlijmen, Gerard J P van Westen. J Chem Inf Model 2017
20
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings.
C A Lipinski, F Lombardo, B W Dominy, P J Feeney. Adv Drug Deliv Rev 2001
C A Lipinski, F Lombardo, B W Dominy, P J Feeney. Adv Drug Deliv Rev 2001
20
Identifying novel adenosine receptor ligands by simultaneous proteochemometric modeling of rat and human bioactivity data.
Gerard J P van Westen, Olaf O van den Hoven, Rianne van der Pijl, Thea Mulder-Krieger, Henk de Vries, Jörg K Wegner, Adriaan P Ijzerman, Herman W T van Vlijmen, Andreas Bender. J Med Chem 2012
Gerard J P van Westen, Olaf O van den Hoven, Rianne van der Pijl, Thea Mulder-Krieger, Henk de Vries, Jörg K Wegner, Adriaan P Ijzerman, Herman W T van Vlijmen, Andreas Bender. J Med Chem 2012
20
Phenylglucosides and the Na+/glucose cotransporter (SGLT1): analysis of interactions.
M P Lostao, B A Hirayama, D D Loo, E M Wright. J Membr Biol 1994
M P Lostao, B A Hirayama, D D Loo, E M Wright. J Membr Biol 1994
20
SGLT1 and SGLT1 Inhibitors: A Role to Be Assessed in the Current Clinical Practice.
Leonardo Spatola, Silvia Finazzi, Claudio Angelini, Marco Dauriz, Salvatore Badalamenti. Diabetes Ther 2018
Leonardo Spatola, Silvia Finazzi, Claudio Angelini, Marco Dauriz, Salvatore Badalamenti. Diabetes Ther 2018
20
LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice.
David R Powell, Melinda G Smith, Deon D Doree, Angela L Harris, Jennifer Greer, Christopher M DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G Carson,[...]. J Pharmacol Exp Ther 2017
David R Powell, Melinda G Smith, Deon D Doree, Angela L Harris, Jennifer Greer, Christopher M DaCosta, Andrea Thompson, Sabrina Jeter-Jones, Wendy Xiong, Kenneth G Carson,[...]. J Pharmacol Exp Ther 2017
20
Na(+)-glucose cotransporter (SGLT) inhibitors as antidiabetic agents. 4. Synthesis and pharmacological properties of 4'-dehydroxyphlorizin derivatives substituted on the B ring.
K Tsujihara, M Hongu, K Saito, H Kawanishi, K Kuriyama, M Matsumoto, A Oku, K Ueta, M Tsuda, A Saito. J Med Chem 1999
K Tsujihara, M Hongu, K Saito, H Kawanishi, K Kuriyama, M Matsumoto, A Oku, K Ueta, M Tsuda, A Saito. J Med Chem 1999
20
Benchmarking of protein descriptor sets in proteochemometric modeling (part 2): modeling performance of 13 amino acid descriptor sets.
Gerard Jp van Westen, Remco F Swier, Isidro Cortes-Ciriano, Jörg K Wegner, John P Overington, Adriaan P Ijzerman, Herman Wt van Vlijmen, Andreas Bender. J Cheminform 2013
Gerard Jp van Westen, Remco F Swier, Isidro Cortes-Ciriano, Jörg K Wegner, John P Overington, Adriaan P Ijzerman, Herman Wt van Vlijmen, Andreas Bender. J Cheminform 2013
20
New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids.
M Sandberg, L Eriksson, J Jonsson, M Sjöström, S Wold. J Med Chem 1998
M Sandberg, L Eriksson, J Jonsson, M Sjöström, S Wold. J Med Chem 1998
20
Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes.
Christine Clar, James Alexander Gill, Rachel Court, Norman Waugh. BMJ Open 2012
Christine Clar, James Alexander Gill, Rachel Court, Norman Waugh. BMJ Open 2012
20
Sodium-glucose cotransport.
Søren Brandt Poulsen, Robert A Fenton, Timo Rieg. Curr Opin Nephrol Hypertens 2015
Søren Brandt Poulsen, Robert A Fenton, Timo Rieg. Curr Opin Nephrol Hypertens 2015
20
The mechanism of sodium and substrate release from the binding pocket of vSGLT.
Akira Watanabe, Seungho Choe, Vincent Chaptal, John M Rosenberg, Ernest M Wright, Michael Grabe, Jeff Abramson. Nature 2010
Akira Watanabe, Seungho Choe, Vincent Chaptal, John M Rosenberg, Ernest M Wright, Michael Grabe, Jeff Abramson. Nature 2010
20
Biology of human sodium glucose transporters.
Ernest M Wright, Donald D F Loo, Bruce A Hirayama. Physiol Rev 2011
Ernest M Wright, Donald D F Loo, Bruce A Hirayama. Physiol Rev 2011
20
Intestinal SGLT1 in metabolic health and disease.
Anders Lehmann, Pamela J Hornby. Am J Physiol Gastrointest Liver Physiol 2016
Anders Lehmann, Pamela J Hornby. Am J Physiol Gastrointest Liver Physiol 2016
20
ChEMBL: a large-scale bioactivity database for drug discovery.
Anna Gaulton, Louisa J Bellis, A Patricia Bento, Jon Chambers, Mark Davies, Anne Hersey, Yvonne Light, Shaun McGlinchey, David Michalovich, Bissan Al-Lazikani,[...]. Nucleic Acids Res 2012
Anna Gaulton, Louisa J Bellis, A Patricia Bento, Jon Chambers, Mark Davies, Anne Hersey, Yvonne Light, Shaun McGlinchey, David Michalovich, Bissan Al-Lazikani,[...]. Nucleic Acids Res 2012
20
Dietary phloridzin reduces blood glucose levels and reverses Sglt1 expression in the small intestine in streptozotocin-induced diabetic mice.
Saeko Masumoto, Yukari Akimoto, Hideaki Oike, Masuko Kobori. J Agric Food Chem 2009
Saeko Masumoto, Yukari Akimoto, Hideaki Oike, Masuko Kobori. J Agric Food Chem 2009
20
Inhibitor binding mode and allosteric regulation of Na+-glucose symporters.
Paola Bisignano, Chiara Ghezzi, Hyunil Jo, Nicholas F Polizzi, Thorsten Althoff, Chakrapani Kalyanaraman, Rosmarie Friemann, Matthew P Jacobson, Ernest M Wright, Michael Grabe. Nat Commun 2018
Paola Bisignano, Chiara Ghezzi, Hyunil Jo, Nicholas F Polizzi, Thorsten Althoff, Chakrapani Kalyanaraman, Rosmarie Friemann, Matthew P Jacobson, Ernest M Wright, Michael Grabe. Nat Commun 2018
20
Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins.
I Stuart Wood, Paul Trayhurn. Br J Nutr 2003
I Stuart Wood, Paul Trayhurn. Br J Nutr 2003
20
The ChEMBL bioactivity database: an update.
A Patrícia Bento, Anna Gaulton, Anne Hersey, Louisa J Bellis, Jon Chambers, Mark Davies, Felix A Krüger, Yvonne Light, Lora Mak, Shaun McGlinchey,[...]. Nucleic Acids Res 2014
A Patrícia Bento, Anna Gaulton, Anne Hersey, Louisa J Bellis, Jon Chambers, Mark Davies, Felix A Krüger, Yvonne Light, Lora Mak, Shaun McGlinchey,[...]. Nucleic Acids Res 2014
20
The ChEMBL database in 2017.
Anna Gaulton, Anne Hersey, Michał Nowotka, A Patrícia Bento, Jon Chambers, David Mendez, Prudence Mutowo, Francis Atkinson, Louisa J Bellis, Elena Cibrián-Uhalte,[...]. Nucleic Acids Res 2017
Anna Gaulton, Anne Hersey, Michał Nowotka, A Patrícia Bento, Jon Chambers, David Mendez, Prudence Mutowo, Francis Atkinson, Louisa J Bellis, Elena Cibrián-Uhalte,[...]. Nucleic Acids Res 2017
20
Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus.
B Komoroski, N Vachharajani, Y Feng, L Li, D Kornhauser, M Pfister. Clin Pharmacol Ther 2009
B Komoroski, N Vachharajani, Y Feng, L Li, D Kornhauser, M Pfister. Clin Pharmacol Ther 2009
20
Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion.
Valentin Gorboulev, Annette Schürmann, Volker Vallon, Helmut Kipp, Alexander Jaschke, Dirk Klessen, Alexandra Friedrich, Stephan Scherneck, Timo Rieg, Robyn Cunard,[...]. Diabetes 2012
Valentin Gorboulev, Annette Schürmann, Volker Vallon, Helmut Kipp, Alexander Jaschke, Dirk Klessen, Alexandra Friedrich, Stephan Scherneck, Timo Rieg, Robyn Cunard,[...]. Diabetes 2012
20
Efficacy and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, as add-on to metformin in type 2 diabetes with mild hyperglycaemia.
J Rosenstock, L J Seman, A Jelaska, S Hantel, S Pinnetti, T Hach, H J Woerle. Diabetes Obes Metab 2013
J Rosenstock, L J Seman, A Jelaska, S Hantel, S Pinnetti, T Hach, H J Woerle. Diabetes Obes Metab 2013
20
Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect.
Philipp F Secker, Sascha Beneke, Nadja Schlichenmaier, Johannes Delp, Simon Gutbier, Marcel Leist, Daniel R Dietrich. Cell Death Dis 2018
Philipp F Secker, Sascha Beneke, Nadja Schlichenmaier, Johannes Delp, Simon Gutbier, Marcel Leist, Daniel R Dietrich. Cell Death Dis 2018
20
Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes.
Nicole C Goodwin, Zhi-Ming Ding, Bryce A Harrison, Eric D Strobel, Angela L Harris, Melinda Smith, Andrea Y Thompson, Wendy Xiong, Faika Mseeh, Debra J Bruce,[...]. J Med Chem 2017
Nicole C Goodwin, Zhi-Ming Ding, Bryce A Harrison, Eric D Strobel, Angela L Harris, Melinda Smith, Andrea Y Thompson, Wendy Xiong, Faika Mseeh, Debra J Bruce,[...]. J Med Chem 2017
20
SLC transporters as therapeutic targets: emerging opportunities.
Lawrence Lin, Sook Wah Yee, Richard B Kim, Kathleen M Giacomini. Nat Rev Drug Discov 2015
Lawrence Lin, Sook Wah Yee, Richard B Kim, Kathleen M Giacomini. Nat Rev Drug Discov 2015
20
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega.
Fabian Sievers, Andreas Wilm, David Dineen, Toby J Gibson, Kevin Karplus, Weizhong Li, Rodrigo Lopez, Hamish McWilliam, Michael Remmert, Johannes Söding,[...]. Mol Syst Biol 2011
Fabian Sievers, Andreas Wilm, David Dineen, Toby J Gibson, Kevin Karplus, Weizhong Li, Rodrigo Lopez, Hamish McWilliam, Michael Remmert, Johannes Söding,[...]. Mol Syst Biol 2011
20
Sotagliflozin, a Dual SGLT1 and SGLT2 Inhibitor, as Adjunct Therapy to Insulin in Type 1 Diabetes.
Arthur T Sands, Brian P Zambrowicz, Julio Rosenstock, Pablo Lapuerta, Bruce W Bode, Satish K Garg, John B Buse, Phillip Banks, Rubina Heptulla, Marc Rendell,[...]. Diabetes Care 2015
Arthur T Sands, Brian P Zambrowicz, Julio Rosenstock, Pablo Lapuerta, Bruce W Bode, Satish K Garg, John B Buse, Phillip Banks, Rubina Heptulla, Marc Rendell,[...]. Diabetes Care 2015
20
QSAR applicabilty domain estimation by projection of the training set descriptor space: a review.
Joanna Jaworska, Nina Nikolova-Jeliazkova, Tom Aldenberg. Altern Lab Anim 2005
Joanna Jaworska, Nina Nikolova-Jeliazkova, Tom Aldenberg. Altern Lab Anim 2005
20
Structure-based identification of OATP1B1/3 inhibitors.
Tom De Bruyn, Gerard J P van Westen, Adriaan P Ijzerman, Bruno Stieger, Peter de Witte, Patrick F Augustijns, Pieter P Annaert. Mol Pharmacol 2013
Tom De Bruyn, Gerard J P van Westen, Adriaan P Ijzerman, Bruno Stieger, Peter de Witte, Patrick F Augustijns, Pieter P Annaert. Mol Pharmacol 2013
20
Which compound to select in lead optimization? Prospectively validated proteochemometric models guide preclinical development.
Gerard J P van Westen, Jörg K Wegner, Peggy Geluykens, Leen Kwanten, Inge Vereycken, Anik Peeters, Adriaan P Ijzerman, Herman W T van Vlijmen, Andreas Bender. PLoS One 2011
Gerard J P van Westen, Jörg K Wegner, Peggy Geluykens, Leen Kwanten, Inge Vereycken, Anik Peeters, Adriaan P Ijzerman, Herman W T van Vlijmen, Andreas Bender. PLoS One 2011
20
Activity, assay and target data curation and quality in the ChEMBL database.
George Papadatos, Anna Gaulton, Anne Hersey, John P Overington. J Comput Aided Mol Des 2015
George Papadatos, Anna Gaulton, Anne Hersey, John P Overington. J Comput Aided Mol Des 2015
20
Discovery of potent α-glucosidase inhibitor flavonols: Insights into mechanism of action through inhibition kinetics and docking simulations.
Didem Şöhretoğlu, Suat Sari, Burak Barut, Arzu Özel. Bioorg Chem 2018
Didem Şöhretoğlu, Suat Sari, Burak Barut, Arzu Özel. Bioorg Chem 2018
20
Uric acid lowering in relation to HbA1c reductions with the SGLT2 inhibitor tofogliflozin.
Motoshi Ouchi, Kenzo Oba, Kohei Kaku, Hideki Suganami, Akihiro Yoshida, Yasunori Fukunaka, Promsuk Jutabha, Asuka Morita, Naoyuki Otani, Keitaro Hayashi,[...]. Diabetes Obes Metab 2018
Motoshi Ouchi, Kenzo Oba, Kohei Kaku, Hideki Suganami, Akihiro Yoshida, Yasunori Fukunaka, Promsuk Jutabha, Asuka Morita, Naoyuki Otani, Keitaro Hayashi,[...]. Diabetes Obes Metab 2018
20
Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS Program randomised clinical trials.
Vlado Perkovic, Dick de Zeeuw, Kenneth W Mahaffey, Greg Fulcher, Ngozi Erondu, Wayne Shaw, Terrance D Barrett, Michele Weidner-Wells, Hsiaowei Deng, David R Matthews,[...]. Lancet Diabetes Endocrinol 2018
Vlado Perkovic, Dick de Zeeuw, Kenneth W Mahaffey, Greg Fulcher, Ngozi Erondu, Wayne Shaw, Terrance D Barrett, Michele Weidner-Wells, Hsiaowei Deng, David R Matthews,[...]. Lancet Diabetes Endocrinol 2018
20
C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors.
Yuichi Koga, Shigeki Sakamaki, Mitsuya Hongu, Eiji Kawanishi, Toshiaki Sakamoto, Yasuo Yamamoto, Hirotaka Kimata, Keiko Nakayama, Chiaki Kuriyama, Yasuaki Matsushita,[...]. Bioorg Med Chem 2013
Yuichi Koga, Shigeki Sakamaki, Mitsuya Hongu, Eiji Kawanishi, Toshiaki Sakamoto, Yasuo Yamamoto, Hirotaka Kimata, Keiko Nakayama, Chiaki Kuriyama, Yasuaki Matsushita,[...]. Bioorg Med Chem 2013
20
Efficacy and safety of dual SGLT 1/2 inhibitor sotagliflozin in type 1 diabetes: meta-analysis of randomised controlled trials.
Giovanni Musso, Roberto Gambino, Maurizio Cassader, Elena Paschetta. BMJ 2019
Giovanni Musso, Roberto Gambino, Maurizio Cassader, Elena Paschetta. BMJ 2019
20
Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1.
Daniel J Drucker. Cell Metab 2018
Daniel J Drucker. Cell Metab 2018
20
SGLT2 inhibitors for the treatment of diabetes: a patent review (2013-2018).
Jyotsana Pandey, Akhilesh K Tamrakar. Expert Opin Ther Pat 2019
Jyotsana Pandey, Akhilesh K Tamrakar. Expert Opin Ther Pat 2019
20
HbA1c and Hypoglycemia Reductions at 24 and 52 Weeks With Sotagliflozin in Combination With Insulin in Adults With Type 1 Diabetes: The European inTandem2 Study.
Thomas Danne, Bertrand Cariou, Phillip Banks, Michael Brandle, Helmut Brath, Edward Franek, Jake A Kushner, Pablo Lapuerta, Darren K McGuire, Anne L Peters,[...]. Diabetes Care 2018
Thomas Danne, Bertrand Cariou, Phillip Banks, Michael Brandle, Helmut Brath, Edward Franek, Jake A Kushner, Pablo Lapuerta, Darren K McGuire, Anne L Peters,[...]. Diabetes Care 2018
20
Development of sotagliflozin, a dual sodium-dependent glucose transporter 1/2 inhibitor.
Pablo Lapuerta, Brian Zambrowicz, Paul Strumph, Arthur Sands. Diab Vasc Dis Res 2015
Pablo Lapuerta, Brian Zambrowicz, Paul Strumph, Arthur Sands. Diab Vasc Dis Res 2015
20
Sodium-glucose cotransporter 2 inhibitors and inflammation in chronic kidney disease: Possible molecular pathways.
Habib Yaribeygi, Alexandra E Butler, Stephen L Atkin, Niki Katsiki, Amirhossein Sahebkar. J Cell Physiol 2018
Habib Yaribeygi, Alexandra E Butler, Stephen L Atkin, Niki Katsiki, Amirhossein Sahebkar. J Cell Physiol 2018
20
Development of a Scalable Synthesis of Tofogliflozin.
Yoshihito Ohtake, Takashi Emura, Masahiro Nishimoto, Koji Takano, Keisuke Yamamoto, Satoshi Tsuchiya, Sang-Yong Yeu, Yasushi Kito, Nobuaki Kimura, Sunao Takeda,[...]. J Org Chem 2016
Yoshihito Ohtake, Takashi Emura, Masahiro Nishimoto, Koji Takano, Keisuke Yamamoto, Satoshi Tsuchiya, Sang-Yong Yeu, Yasushi Kito, Nobuaki Kimura, Sunao Takeda,[...]. J Org Chem 2016
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.