Ying Yin, Mengyu Wu, Lejla Zubcevic, William F Borschel, Gabriel C Lander, Seok-Yong Lee. Science 2018
Times Cited: 146
Times Cited: 146
Times Cited
Times Co-cited
Similarity
Identification of a cold receptor reveals a general role for TRP channels in thermosensation.
David D McKemy, Werner M Neuhausser, David Julius. Nature 2002
David D McKemy, Werner M Neuhausser, David Julius. Nature 2002
40
A TRP channel that senses cold stimuli and menthol.
Andrea M Peier, Aziz Moqrich, Anne C Hergarden, Alison J Reeve, David A Andersson, Gina M Story, Taryn J Earley, Ilaria Dragoni, Peter McIntyre, Stuart Bevan,[...]. Cell 2002
Andrea M Peier, Aziz Moqrich, Anne C Hergarden, Alison J Reeve, David A Andersson, Gina M Story, Taryn J Earley, Ilaria Dragoni, Peter McIntyre, Stuart Bevan,[...]. Cell 2002
39
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Ying Yin, Son C Le, Allen L Hsu, Mario J Borgnia, Huanghe Yang, Seok-Yong Lee. Science 2019
Ying Yin, Son C Le, Allen L Hsu, Mario J Borgnia, Huanghe Yang, Seok-Yong Lee. Science 2019
38
Structure of the human TRPM4 ion channel in a lipid nanodisc.
Henriette E Autzen, Alexander G Myasnikov, Melody G Campbell, Daniel Asarnow, David Julius, Yifan Cheng. Science 2018
Henriette E Autzen, Alexander G Myasnikov, Melody G Campbell, Daniel Asarnow, David Julius, Yifan Cheng. Science 2018
33
TRPV1 structures in distinct conformations reveal activation mechanisms.
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
31
Structural insights into TRPM8 inhibition and desensitization.
Melinda M Diver, Yifan Cheng, David Julius. Science 2019
Melinda M Diver, Yifan Cheng, David Julius. Science 2019
50
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Yuan Gao, Erhu Cao, David Julius, Yifan Cheng. Nature 2016
Yuan Gao, Erhu Cao, David Julius, Yifan Cheng. Nature 2016
29
Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
29
Structures of the calcium-activated, non-selective cation channel TRPM4.
Jiangtao Guo, Ji She, Weizhong Zeng, Qingfeng Chen, Xiao-Chen Bai, Youxing Jiang. Nature 2017
Jiangtao Guo, Ji She, Weizhong Zeng, Qingfeng Chen, Xiao-Chen Bai, Youxing Jiang. Nature 2017
28
The menthol receptor TRPM8 is the principal detector of environmental cold.
Diana M Bautista, Jan Siemens, Joshua M Glazer, Pamela R Tsuruda, Allan I Basbaum, Cheryl L Stucky, Sven-Eric Jordt, David Julius. Nature 2007
Diana M Bautista, Jan Siemens, Joshua M Glazer, Pamela R Tsuruda, Allan I Basbaum, Cheryl L Stucky, Sven-Eric Jordt, David Julius. Nature 2007
25
Electron cryo-microscopy structure of a human TRPM4 channel.
Paige A Winkler, Yihe Huang, Weinan Sun, Juan Du, Wei Lü. Nature 2017
Paige A Winkler, Yihe Huang, Weinan Sun, Juan Du, Wei Lü. Nature 2017
25
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation.
Zhe Zhang, Balázs Tóth, Andras Szollosi, Jue Chen, László Csanády. Elife 2018
Zhe Zhang, Balázs Tóth, Andras Szollosi, Jue Chen, László Csanády. Elife 2018
27
TRPM8 is required for cold sensation in mice.
Ajay Dhaka, Amber N Murray, Jayanti Mathur, Taryn J Earley, Matt J Petrus, Ardem Patapoutian. Neuron 2007
Ajay Dhaka, Amber N Murray, Jayanti Mathur, Taryn J Earley, Matt J Petrus, Ardem Patapoutian. Neuron 2007
19
Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium.
Yihe Huang, Paige A Winkler, Weinan Sun, Wei Lü, Juan Du. Nature 2018
Yihe Huang, Paige A Winkler, Weinan Sun, Wei Lü, Juan Du. Nature 2018
19
The capsaicin receptor: a heat-activated ion channel in the pain pathway.
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
19
PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain.
Tibor Rohács, Coeli M B Lopes, Ioannis Michailidis, Diomedes E Logothetis. Nat Neurosci 2005
Tibor Rohács, Coeli M B Lopes, Ioannis Michailidis, Diomedes E Logothetis. Nat Neurosci 2005
18
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli.
Thomas Voets, Grzegorz Owsianik, Annelies Janssens, Karel Talavera, Bernd Nilius. Nat Chem Biol 2007
Thomas Voets, Grzegorz Owsianik, Annelies Janssens, Karel Talavera, Bernd Nilius. Nat Chem Biol 2007
18
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
18
Structure and gating mechanism of the transient receptor potential channel TRPV3.
Appu K Singh, Luke L McGoldrick, Alexander I Sobolevsky. Nat Struct Mol Biol 2018
Appu K Singh, Luke L McGoldrick, Alexander I Sobolevsky. Nat Struct Mol Biol 2018
20
Cryo-electron microscopy structure of the TRPV2 ion channel.
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
17
Structure of full-length human TRPM4.
Jingjing Duan, Zongli Li, Jian Li, Ana Santa-Cruz, Silvia Sanchez-Martinez, Jin Zhang, David E Clapham. Proc Natl Acad Sci U S A 2018
Jingjing Duan, Zongli Li, Jian Li, Ana Santa-Cruz, Silvia Sanchez-Martinez, Jin Zhang, David E Clapham. Proc Natl Acad Sci U S A 2018
34
Structures and gating mechanism of human TRPM2.
Longfei Wang, Tian-Min Fu, Yiming Zhou, Shiyu Xia, Anna Greka, Hao Wu. Science 2018
Longfei Wang, Tian-Min Fu, Yiming Zhou, Shiyu Xia, Anna Greka, Hao Wu. Science 2018
21
High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol.
Michael Bandell, Adrienne E Dubin, Matt J Petrus, Anthony Orth, Jayanti Mathur, Sun Wook Hwang, Ardem Patapoutian. Nat Neurosci 2006
Michael Bandell, Adrienne E Dubin, Matt J Petrus, Anthony Orth, Jayanti Mathur, Sun Wook Hwang, Ardem Patapoutian. Nat Neurosci 2006
16
Attenuated cold sensitivity in TRPM8 null mice.
Raymond W Colburn, Mary Lou Lubin, Dennis J Stone, Yan Wang, Danielle Lawrence, Michael R D'Andrea, Michael R Brandt, Yi Liu, Christopher M Flores, Ning Qin. Neuron 2007
Raymond W Colburn, Mary Lou Lubin, Dennis J Stone, Yan Wang, Danielle Lawrence, Michael R D'Andrea, Michael R Brandt, Yi Liu, Christopher M Flores, Ning Qin. Neuron 2007
16
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel.
Huai-hu Chuang, Werner M Neuhausser, David Julius. Neuron 2004
Huai-hu Chuang, Werner M Neuhausser, David Julius. Neuron 2004
15
Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Jingjing Duan, Zongli Li, Jian Li, Raymond E Hulse, Ana Santa-Cruz, William C Valinsky, Sunday A Abiria, Grigory Krapivinsky, Jin Zhang, David E Clapham. Proc Natl Acad Sci U S A 2018
Jingjing Duan, Zongli Li, Jian Li, Raymond E Hulse, Ana Santa-Cruz, William C Valinsky, Sunday A Abiria, Grigory Krapivinsky, Jin Zhang, David E Clapham. Proc Natl Acad Sci U S A 2018
24
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.
Thomas Voets, Guy Droogmans, Ulrich Wissenbach, Annelies Janssens, Veit Flockerzi, Bernd Nilius. Nature 2004
Thomas Voets, Guy Droogmans, Ulrich Wissenbach, Annelies Janssens, Veit Flockerzi, Bernd Nilius. Nature 2004
14
Conformational ensemble of the human TRPV3 ion channel.
Lejla Zubcevic, Mark A Herzik, Mengyu Wu, William F Borschel, Marscha Hirschi, Albert S Song, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2018
Lejla Zubcevic, Mark A Herzik, Mengyu Wu, William F Borschel, Marscha Hirschi, Albert S Song, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2018
22
Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Zengqin Deng, Navid Paknejad, Grigory Maksaev, Monica Sala-Rabanal, Colin G Nichols, Richard K Hite, Peng Yuan. Nat Struct Mol Biol 2018
Zengqin Deng, Navid Paknejad, Grigory Maksaev, Monica Sala-Rabanal, Colin G Nichols, Richard K Hite, Peng Yuan. Nat Struct Mol Biol 2018
14
Structure of the mouse TRPC4 ion channel.
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
20
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
14
Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate.
Beiying Liu, Feng Qin. J Neurosci 2005
Beiying Liu, Feng Qin. J Neurosci 2005
13
TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization.
Pierre Launay, Andrea Fleig, Anne Laure Perraud, Andrew M Scharenberg, Reinhold Penner, Jean Pierre Kinet. Cell 2002
Pierre Launay, Andrea Fleig, Anne Laure Perraud, Andrew M Scharenberg, Reinhold Penner, Jean Pierre Kinet. Cell 2002
13
Structure of the human lipid-gated cation channel TRPC3.
Chen Fan, Wooyoung Choi, Weinan Sun, Juan Du, Wei Lü. Elife 2018
Chen Fan, Wooyoung Choi, Weinan Sun, Juan Du, Wei Lü. Elife 2018
20
Temperature and voltage coupling to channel opening in transient receptor potential melastatin 8 (TRPM8).
Natalia Raddatz, Juan P Castillo, Carlos Gonzalez, Osvaldo Alvarez, Ramon Latorre. J Biol Chem 2014
Natalia Raddatz, Juan P Castillo, Carlos Gonzalez, Osvaldo Alvarez, Ramon Latorre. J Biol Chem 2014
35
Structure of the receptor-activated human TRPC6 and TRPC3 ion channels.
Qinglin Tang, Wenjun Guo, Li Zheng, Jing-Xiang Wu, Meng Liu, Xindi Zhou, Xiaolin Zhang, Lei Chen. Cell Res 2018
Qinglin Tang, Wenjun Guo, Li Zheng, Jing-Xiang Wu, Meng Liu, Xindi Zhou, Xiaolin Zhang, Lei Chen. Cell Res 2018
15
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Taylor E T Hughes, David T Lodowski, Kevin W Huynh, Aysenur Yazici, John Del Rosario, Abhijeet Kapoor, Sandip Basak, Amrita Samanta, Xu Han, Sudha Chakrapani,[...]. Nat Struct Mol Biol 2018
Taylor E T Hughes, David T Lodowski, Kevin W Huynh, Aysenur Yazici, John Del Rosario, Abhijeet Kapoor, Sandip Basak, Amrita Samanta, Xu Han, Sudha Chakrapani,[...]. Nat Struct Mol Biol 2018
19
Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer.
M Jesús Pérez de Vega, Isabel Gómez-Monterrey, Antonio Ferrer-Montiel, Rosario González-Muñiz. J Med Chem 2016
M Jesús Pérez de Vega, Isabel Gómez-Monterrey, Antonio Ferrer-Montiel, Rosario González-Muñiz. J Med Chem 2016
31
A structural overview of the ion channels of the TRPM family.
Yihe Huang, Ralf Fliegert, Andreas H Guse, Wei Lü, Juan Du. Cell Calcium 2020
Yihe Huang, Ralf Fliegert, Andreas H Guse, Wei Lü, Juan Du. Cell Calcium 2020
17
Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain.
Mark D Andrews, Kerry Af Forselles, Kevin Beaumont, Sébastien R G Galan, Paul A Glossop, Mathilde Grenie, Alan Jessiman, Amy S Kenyon, Graham Lunn, Graham Maw,[...]. ACS Med Chem Lett 2015
Mark D Andrews, Kerry Af Forselles, Kevin Beaumont, Sébastien R G Galan, Paul A Glossop, Mathilde Grenie, Alan Jessiman, Amy S Kenyon, Graham Lunn, Graham Maw,[...]. ACS Med Chem Lett 2015
22
Clues to understanding cold sensation: thermodynamics and electrophysiological analysis of the cold receptor TRPM8.
Sebastian Brauchi, Patricio Orio, Ramon Latorre. Proc Natl Acad Sci U S A 2004
Sebastian Brauchi, Patricio Orio, Ramon Latorre. Proc Natl Acad Sci U S A 2004
11
Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.
Marscha Hirschi, Mark A Herzik, Jinhong Wie, Yang Suo, William F Borschel, Dejian Ren, Gabriel C Lander, Seok-Yong Lee. Nature 2017
Marscha Hirschi, Mark A Herzik, Jinhong Wie, Yang Suo, William F Borschel, Dejian Ren, Gabriel C Lander, Seok-Yong Lee. Nature 2017
15
Crystal structure of the epithelial calcium channel TRPV6.
Kei Saotome, Appu K Singh, Maria V Yelshanskaya, Alexander I Sobolevsky. Nature 2016
Kei Saotome, Appu K Singh, Maria V Yelshanskaya, Alexander I Sobolevsky. Nature 2016
11
Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Appu K Singh, Kei Saotome, Luke L McGoldrick, Alexander I Sobolevsky. Nat Commun 2018
Appu K Singh, Kei Saotome, Luke L McGoldrick, Alexander I Sobolevsky. Nat Commun 2018
23
A TRP channel trio mediates acute noxious heat sensing.
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
11
Discovery of TRPM8 Antagonist ( S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine.
Daniel B Horne, Kaustav Biswas, James Brown, Michael D Bartberger, Jeffrey Clarine, Carl D Davis, Vijay K Gore, Scott Harried, Michelle Horner, Matthew R Kaller,[...]. J Med Chem 2018
Daniel B Horne, Kaustav Biswas, James Brown, Michael D Bartberger, Jeffrey Clarine, Carl D Davis, Vijay K Gore, Scott Harried, Michelle Horner, Matthew R Kaller,[...]. J Med Chem 2018
47
A thermodynamic framework for understanding temperature sensing by transient receptor potential (TRP) channels.
David E Clapham, Christopher Miller. Proc Natl Acad Sci U S A 2011
David E Clapham, Christopher Miller. Proc Natl Acad Sci U S A 2011
11
Electron cryo-microscopy structure of the canonical TRPC4 ion channel.
Deivanayagabarathy Vinayagam, Thomas Mager, Amir Apelbaum, Arne Bothe, Felipe Merino, Oliver Hofnagel, Christos Gatsogiannis, Stefan Raunser. Elife 2018
Deivanayagabarathy Vinayagam, Thomas Mager, Amir Apelbaum, Arne Bothe, Felipe Merino, Oliver Hofnagel, Christos Gatsogiannis, Stefan Raunser. Elife 2018
17
Structural basis of temperature sensation by the TRP channel TRPV3.
Appu K Singh, Luke L McGoldrick, Lusine Demirkhanyan, Merfilius Leslie, Eleonora Zakharian, Alexander I Sobolevsky. Nat Struct Mol Biol 2019
Appu K Singh, Luke L McGoldrick, Lusine Demirkhanyan, Merfilius Leslie, Eleonora Zakharian, Alexander I Sobolevsky. Nat Struct Mol Biol 2019
26
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.