Sunil R Hingorani, Lei Zheng, Andrea J Bullock, Tara E Seery, William P Harris, Darren S Sigal, Fadi Braiteh, Paul S Ritch, Mark M Zalupski, Nathan Bahary, Paul E Oberstein, Andrea Wang-Gillam, Wilson Wu, Dimitrios Chondros, Ping Jiang, Sihem Khelifa, Jie Pu, Carrie Aldrich, Andrew E Hendifar. J Clin Oncol 2018
Times Cited: 226
Times Cited: 226
Times Cited
Times Co-cited
Similarity
Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma.
Paolo P Provenzano, Carlos Cuevas, Amy E Chang, Vikas K Goel, Daniel D Von Hoff, Sunil R Hingorani. Cancer Cell 2012
Paolo P Provenzano, Carlos Cuevas, Amy E Chang, Vikas K Goel, Daniel D Von Hoff, Sunil R Hingorani. Cancer Cell 2012
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Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.
Andrew D Rhim, Paul E Oberstein, Dafydd H Thomas, Emily T Mirek, Carmine F Palermo, Stephen A Sastra, Erin N Dekleva, Tyler Saunders, Claudia P Becerra, Ian W Tattersall,[...]. Cancer Cell 2014
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Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.
Michael A Jacobetz, Derek S Chan, Albrecht Neesse, Tashinga E Bapiro, Natalie Cook, Kristopher K Frese, Christine Feig, Tomoaki Nakagawa, Meredith E Caldwell, Heather I Zecchini,[...]. Gut 2013
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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Kenneth P Olive, Michael A Jacobetz, Christian J Davidson, Aarthi Gopinathan, Dominick McIntyre, Davina Honess, Basetti Madhu, Mae A Goldgraben, Meredith E Caldwell, David Allard,[...]. Science 2009
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Phase IB/II Randomized Study of FOLFIRINOX Plus Pegylated Recombinant Human Hyaluronidase Versus FOLFIRINOX Alone in Patients With Metastatic Pancreatic Adenocarcinoma: SWOG S1313.
Ramesh K Ramanathan, Shannon L McDonough, Philip A Philip, Sunil R Hingorani, Jill Lacy, Jeremy S Kortmansky, Jaykumar Thumar, E Gabriela Chiorean, Anthony F Shields, Deepti Behl,[...]. J Clin Oncol 2019
Ramesh K Ramanathan, Shannon L McDonough, Philip A Philip, Sunil R Hingorani, Jill Lacy, Jeremy S Kortmansky, Jaykumar Thumar, E Gabriela Chiorean, Anthony F Shields, Deepti Behl,[...]. J Clin Oncol 2019
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Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine.
Daniel D Von Hoff, Thomas Ervin, Francis P Arena, E Gabriela Chiorean, Jeffrey Infante, Malcolm Moore, Thomas Seay, Sergei A Tjulandin, Wen Wee Ma, Mansoor N Saleh,[...]. N Engl J Med 2013
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Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
Daniel Öhlund, Abram Handly-Santana, Giulia Biffi, Ela Elyada, Ana S Almeida, Mariano Ponz-Sarvise, Vincenzo Corbo, Tobiloba E Oni, Stephen A Hearn, Eun Jung Lee,[...]. J Exp Med 2017
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FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer.
Thierry Conroy, Françoise Desseigne, Marc Ychou, Olivier Bouché, Rosine Guimbaud, Yves Bécouarn, Antoine Adenis, Jean-Luc Raoul, Sophie Gourgou-Bourgade, Christelle de la Fouchardière,[...]. N Engl J Med 2011
Thierry Conroy, Françoise Desseigne, Marc Ychou, Olivier Bouché, Rosine Guimbaud, Yves Bécouarn, Antoine Adenis, Jean-Luc Raoul, Sophie Gourgou-Bourgade, Christelle de la Fouchardière,[...]. N Engl J Med 2011
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Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.
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Randomized Phase III Trial of Pegvorhyaluronidase Alfa With Nab-Paclitaxel Plus Gemcitabine for Patients With Hyaluronan-High Metastatic Pancreatic Adenocarcinoma.
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Genomic analyses identify molecular subtypes of pancreatic cancer.
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Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.
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Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.
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Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer.
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Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.
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Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma.
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Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer.
Sunil R Hingorani, William P Harris, J Thaddeus Beck, Boris A Berdov, Stephanie A Wagner, Eduard M Pshevlotsky, Sergei A Tjulandin, Oleg A Gladkov, Randall F Holcombe, Ronald Korn,[...]. Clin Cancer Res 2016
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Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.
Mara H Sherman, Ruth T Yu, Dannielle D Engle, Ning Ding, Annette R Atkins, Herve Tiriac, Eric A Collisson, Frances Connor, Terry Van Dyke, Serguei Kozlov,[...]. Cell 2014
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Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer.
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Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.
Richard A Moffitt, Raoud Marayati, Elizabeth L Flate, Keith E Volmar, S Gabriela Herrera Loeza, Katherine A Hoadley, Naim U Rashid, Lindsay A Williams, Samuel C Eaton, Alexander H Chung,[...]. Nat Genet 2015
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IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma.
Giulia Biffi, Tobiloba E Oni, Benjamin Spielman, Yuan Hao, Ela Elyada, Youngkyu Park, Jonathan Preall, David A Tuveson. Cancer Discov 2019
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Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer.
Daniel V T Catenacci, Melissa R Junttila, Theodore Karrison, Nathan Bahary, Margit N Horiba, Sreenivasa R Nattam, Robert Marsh, James Wallace, Mark Kozloff, Lakshmi Rajdev,[...]. J Clin Oncol 2015
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A framework for advancing our understanding of cancer-associated fibroblasts.
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FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer.
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Safety and activity of anti-PD-L1 antibody in patients with advanced cancer.
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Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.
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Why HALO 301 Failed and Implications for Treatment of Pancreatic Cancer.
Nausheen Hakim, Rajvi Patel, Craig Devoe, Muhammad W Saif. Pancreas (Fairfax) 2019
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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.
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Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial.
Janet E Murphy, Jennifer Y Wo, David P Ryan, Jeffrey W Clark, Wenqing Jiang, Beow Y Yeap, Lorraine C Drapek, Leilana Ly, Christian V Baglini, Lawrence S Blaszkowsky,[...]. JAMA Oncol 2019
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Activity of Mesothelin-Specific Chimeric Antigen Receptor T Cells Against Pancreatic Carcinoma Metastases in a Phase 1 Trial.
Gregory L Beatty, Mark H O'Hara, Simon F Lacey, Drew A Torigian, Farzana Nazimuddin, Fang Chen, Irina M Kulikovskaya, Michael C Soulen, Maureen McGarvey, Anne Marie Nelson,[...]. Gastroenterology 2018
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Sonic hedgehog promotes desmoplasia in pancreatic cancer.
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Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels.
Vikash P Chauhan, John D Martin, Hao Liu, Delphine A Lacorre, Saloni R Jain, Sergey V Kozin, Triantafyllos Stylianopoulos, Ahmed S Mousa, Xiaoxing Han, Pichet Adstamongkonkul,[...]. Nat Commun 2013
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CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans.
Gregory L Beatty, Elena G Chiorean, Matthew P Fishman, Babak Saboury, Ursina R Teitelbaum, Weijing Sun, Richard D Huhn, Wenru Song, Dongguang Li, Leslie L Sharp,[...]. Science 2011
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HALO-109-301: a Phase III trial of PEGPH20 (with gemcitabine and nab-paclitaxel) in hyaluronic acid-high stage IV pancreatic cancer.
Gary J Doherty, Margaret Tempero, Pippa G Corrie. Future Oncol 2018
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CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer.
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A Phase I Study of FOLFIRINOX Plus IPI-926, a Hedgehog Pathway Inhibitor, for Advanced Pancreatic Adenocarcinoma.
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Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma.
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Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.
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Safety and survival with GVAX pancreas prime and Listeria Monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer.
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The tumour microenvironment in pancreatic cancer - clinical challenges and opportunities.
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Enzymatic depletion of tumor hyaluronan induces antitumor responses in preclinical animal models.
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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.