Anders B Wulff, Børge G Nordestgaard, Anne Tybjærg-Hansen. Arterioscler Thromb Vasc Biol 2018
Times Cited: 46
Times Cited: 46
Times Cited
Times Co-cited
Similarity
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
Jacy Crosby, Gina M Peloso, Paul L Auer, David R Crosslin, Nathan O Stitziel, Leslie A Lange, Yingchang Lu, Zheng-zheng Tang, He Zhang, George Hindy,[...]. N Engl J Med 2014
Jacy Crosby, Gina M Peloso, Paul L Auer, David R Crosslin, Nathan O Stitziel, Leslie A Lange, Yingchang Lu, Zheng-zheng Tang, He Zhang, George Hindy,[...]. N Engl J Med 2014
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Loss-of-function mutations in APOC3 and risk of ischemic vascular disease.
Anders Berg Jørgensen, Ruth Frikke-Schmidt, Børge G Nordestgaard, Anne Tybjærg-Hansen. N Engl J Med 2014
Anders Berg Jørgensen, Ruth Frikke-Schmidt, Børge G Nordestgaard, Anne Tybjærg-Hansen. N Engl J Med 2014
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A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection.
Toni I Pollin, Coleen M Damcott, Haiqing Shen, Sandra H Ott, John Shelton, Richard B Horenstein, Wendy Post, John C McLenithan, Lawrence F Bielak, Patricia A Peyser,[...]. Science 2008
Toni I Pollin, Coleen M Damcott, Haiqing Shen, Sandra H Ott, John Shelton, Richard B Horenstein, Wendy Post, John C McLenithan, Lawrence F Bielak, Patricia A Peyser,[...]. Science 2008
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Targeting APOC3 in the familial chylomicronemia syndrome.
Daniel Gaudet, Diane Brisson, Karine Tremblay, Veronica J Alexander, Walter Singleton, Steven G Hughes, Richard S Geary, Brenda F Baker, Mark J Graham, Rosanne M Crooke,[...]. N Engl J Med 2014
Daniel Gaudet, Diane Brisson, Karine Tremblay, Veronica J Alexander, Walter Singleton, Steven G Hughes, Richard S Geary, Brenda F Baker, Mark J Graham, Rosanne M Crooke,[...]. N Engl J Med 2014
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Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia.
Daniel Gaudet, Veronica J Alexander, Brenda F Baker, Diane Brisson, Karine Tremblay, Walter Singleton, Richard S Geary, Steven G Hughes, Nicholas J Viney, Mark J Graham,[...]. N Engl J Med 2015
Daniel Gaudet, Veronica J Alexander, Brenda F Baker, Diane Brisson, Karine Tremblay, Walter Singleton, Richard S Geary, Steven G Hughes, Nicholas J Viney, Mark J Graham,[...]. N Engl J Med 2015
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Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome.
Joseph L Witztum, Daniel Gaudet, Steven D Freedman, Veronica J Alexander, Andres Digenio, Karren R Williams, Qingqing Yang, Steven G Hughes, Richard S Geary, Marcello Arca,[...]. N Engl J Med 2019
Joseph L Witztum, Daniel Gaudet, Steven D Freedman, Veronica J Alexander, Andres Digenio, Karren R Williams, Qingqing Yang, Steven G Hughes, Richard S Geary, Marcello Arca,[...]. N Engl J Med 2019
34
Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans.
Mark J Graham, Richard G Lee, Thomas A Bell, Wuxia Fu, Adam E Mullick, Veronica J Alexander, Walter Singleton, Nick Viney, Richard Geary, John Su,[...]. Circ Res 2013
Mark J Graham, Richard G Lee, Thomas A Bell, Wuxia Fu, Adam E Mullick, Veronica J Alexander, Walter Singleton, Nick Viney, Richard Geary, John Su,[...]. Circ Res 2013
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Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease.
Brian A Ference, John J P Kastelein, Kausik K Ray, Henry N Ginsberg, M John Chapman, Chris J Packard, Ulrich Laufs, Clare Oliver-Williams, Angela M Wood, Adam S Butterworth,[...]. JAMA 2019
Brian A Ference, John J P Kastelein, Kausik K Ray, Henry N Ginsberg, M John Chapman, Chris J Packard, Ulrich Laufs, Clare Oliver-Williams, Angela M Wood, Adam S Butterworth,[...]. JAMA 2019
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Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.
Frederick E Dewey, Viktoria Gusarova, Richard L Dunbar, Colm O'Dushlaine, Claudia Schurmann, Omri Gottesman, Shane McCarthy, Cristopher V Van Hout, Shannon Bruse, Hayes M Dansky,[...]. N Engl J Med 2017
Frederick E Dewey, Viktoria Gusarova, Richard L Dunbar, Colm O'Dushlaine, Claudia Schurmann, Omri Gottesman, Shane McCarthy, Cristopher V Van Hout, Shannon Bruse, Hayes M Dansky,[...]. N Engl J Med 2017
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N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levels.
Veronica J Alexander, Shuting Xia, Eunju Hurh, Steven G Hughes, Louis O'Dea, Richard S Geary, Joseph L Witztum, Sotirios Tsimikas. Eur Heart J 2019
Veronica J Alexander, Shuting Xia, Eunju Hurh, Steven G Hughes, Louis O'Dea, Richard S Geary, Joseph L Witztum, Sotirios Tsimikas. Eur Heart J 2019
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ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.
Philip L S M Gordts, Ryan Nock, Ni-Huiping Son, Bastian Ramms, Irene Lew, Jon C Gonzales, Bryan E Thacker, Debapriya Basu, Richard G Lee, Adam E Mullick,[...]. J Clin Invest 2016
Philip L S M Gordts, Ryan Nock, Ni-Huiping Son, Bastian Ramms, Irene Lew, Jon C Gonzales, Bryan E Thacker, Debapriya Basu, Richard G Lee, Adam E Mullick,[...]. J Clin Invest 2016
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Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides.
Mark J Graham, Richard G Lee, Teresa A Brandt, Li-Jung Tai, Wuxia Fu, Raechel Peralta, Rosie Yu, Eunju Hurh, Erika Paz, Bradley W McEvoy,[...]. N Engl J Med 2017
Mark J Graham, Richard G Lee, Teresa A Brandt, Li-Jung Tai, Wuxia Fu, Raechel Peralta, Rosie Yu, Eunju Hurh, Erika Paz, Bradley W McEvoy,[...]. N Engl J Med 2017
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Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study.
Julian C van Capelleveen, Sophie J Bernelot Moens, Xiaohong Yang, John J P Kastelein, Nicholas J Wareham, Aeilko H Zwinderman, Erik S G Stroes, Joseph L Witztum, G Kees Hovingh, Kay-Tee Khaw,[...]. Arterioscler Thromb Vasc Biol 2017
Julian C van Capelleveen, Sophie J Bernelot Moens, Xiaohong Yang, John J P Kastelein, Nicholas J Wareham, Aeilko H Zwinderman, Erik S G Stroes, Joseph L Witztum, G Kees Hovingh, Kay-Tee Khaw,[...]. Arterioscler Thromb Vasc Biol 2017
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Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity.
Danish Saleheen, Pradeep Natarajan, Irina M Armean, Wei Zhao, Asif Rasheed, Sumeet A Khetarpal, Hong-Hee Won, Konrad J Karczewski, Anne H O'Donnell-Luria, Kaitlin E Samocha,[...]. Nature 2017
Danish Saleheen, Pradeep Natarajan, Irina M Armean, Wei Zhao, Asif Rasheed, Sumeet A Khetarpal, Hong-Hee Won, Konrad J Karczewski, Anne H O'Donnell-Luria, Kaitlin E Samocha,[...]. Nature 2017
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Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia.
Deepak L Bhatt, P Gabriel Steg, Michael Miller, Eliot A Brinton, Terry A Jacobson, Steven B Ketchum, Ralph T Doyle, Rebecca A Juliano, Lixia Jiao, Craig Granowitz,[...]. N Engl J Med 2019
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Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia.
Sandrine Caron, An Verrijken, Ilse Mertens, Carolina Huaman Samanez, Gisèle Mautino, Joel T Haas, Daniel Duran-Sandoval, Janne Prawitt, Sven Francque, Emmanuelle Vallez,[...]. Arterioscler Thromb Vasc Biol 2011
Sandrine Caron, An Verrijken, Ilse Mertens, Carolina Huaman Samanez, Gisèle Mautino, Joel T Haas, Daniel Duran-Sandoval, Janne Prawitt, Sven Francque, Emmanuelle Vallez,[...]. Arterioscler Thromb Vasc Biol 2011
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Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel.
Brian A Ference, Henry N Ginsberg, Ian Graham, Kausik K Ray, Chris J Packard, Eric Bruckert, Robert A Hegele, Ronald M Krauss, Frederick J Raal, Heribert Schunkert,[...]. Eur Heart J 2017
Brian A Ference, Henry N Ginsberg, Ian Graham, Kausik K Ray, Chris J Packard, Eric Bruckert, Robert A Hegele, Ronald M Krauss, Frederick J Raal, Heribert Schunkert,[...]. Eur Heart J 2017
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Effects of APOC3 Heterozygous Deficiency on Plasma Lipid and Lipoprotein Metabolism.
Gissette Reyes-Soffer, Carol Sztalryd, Richard B Horenstein, Stephen Holleran, Anastasiya Matveyenko, Tiffany Thomas, Renu Nandakumar, Colleen Ngai, Wahida Karmally, Henry N Ginsberg,[...]. Arterioscler Thromb Vasc Biol 2019
Gissette Reyes-Soffer, Carol Sztalryd, Richard B Horenstein, Stephen Holleran, Anastasiya Matveyenko, Tiffany Thomas, Renu Nandakumar, Colleen Ngai, Wahida Karmally, Henry N Ginsberg,[...]. Arterioscler Thromb Vasc Biol 2019
22
ANGPTL3 Deficiency and Protection Against Coronary Artery Disease.
Nathan O Stitziel, Amit V Khera, Xiao Wang, Andrew J Bierhals, A Christina Vourakis, Alexandra E Sperry, Pradeep Natarajan, Derek Klarin, Connor A Emdin, Seyedeh M Zekavat,[...]. J Am Coll Cardiol 2017
Nathan O Stitziel, Amit V Khera, Xiao Wang, Andrew J Bierhals, A Christina Vourakis, Alexandra E Sperry, Pradeep Natarajan, Derek Klarin, Connor A Emdin, Seyedeh M Zekavat,[...]. J Am Coll Cardiol 2017
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Triglyceride-Rich Lipoproteins and Atherosclerotic Cardiovascular Disease: New Insights From Epidemiology, Genetics, and Biology.
Børge G Nordestgaard. Circ Res 2016
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Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III.
Raimund Pechlaner, Sotirios Tsimikas, Xiaoke Yin, Peter Willeit, Ferheen Baig, Peter Santer, Friedrich Oberhollenzer, Georg Egger, Joseph L Witztum, Veronica J Alexander,[...]. J Am Coll Cardiol 2017
Raimund Pechlaner, Sotirios Tsimikas, Xiaoke Yin, Peter Willeit, Ferheen Baig, Peter Santer, Friedrich Oberhollenzer, Georg Egger, Joseph L Witztum, Veronica J Alexander,[...]. J Am Coll Cardiol 2017
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Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes.
Andres Digenio, Richard L Dunbar, Veronica J Alexander, Marcus Hompesch, Linda Morrow, Richard G Lee, Mark J Graham, Steven G Hughes, Rosie Yu, Walter Singleton,[...]. Diabetes Care 2016
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Apolipoprotein C-III in triglyceride-rich lipoprotein metabolism.
Bastian Ramms, Philip L S M Gordts. Curr Opin Lipidol 2018
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Emerging Evidence that ApoC-III Inhibitors Provide Novel Options to Reduce the Residual CVD.
Marja-Riitta Taskinen, Chris J Packard, Jan Borén. Curr Atheroscler Rep 2019
Marja-Riitta Taskinen, Chris J Packard, Jan Borén. Curr Atheroscler Rep 2019
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The crucial roles of apolipoproteins E and C-III in apoB lipoprotein metabolism in normolipidemia and hypertriglyceridemia.
Frank M Sacks. Curr Opin Lipidol 2015
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Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice.
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Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.
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Remnant cholesterol as a causal risk factor for ischemic heart disease.
Anette Varbo, Marianne Benn, Anne Tybjærg-Hansen, Anders B Jørgensen, Ruth Frikke-Schmidt, Børge G Nordestgaard. J Am Coll Cardiol 2013
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Apolipoprotein C-III: From Pathophysiology to Pharmacology.
Giuseppe Danilo Norata, Sotirios Tsimikas, Angela Pirillo, Alberico L Catapano. Trends Pharmacol Sci 2015
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The risk of cardiovascular events with increased apolipoprotein CIII: A systematic review and meta-analysis.
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Evinacumab for Homozygous Familial Hypercholesterolemia.
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Missense mutation in APOC3 within the C-terminal lipid binding domain of human ApoC-III results in impaired assembly and secretion of triacylglycerol-rich very low density lipoproteins: evidence that ApoC-III plays a major role in the formation of lipid precursors within the microsomal lumen.
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Changes in low-density lipoprotein size phenotypes associate with changes in apolipoprotein C-III glycoforms after dietary interventions.
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Inhibition of lipoprotein lipase by an apoprotein of human very low density lipoprotein.
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Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo.
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Major lipids, apolipoproteins, and risk of vascular disease.
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Why Is Apolipoprotein CIII Emerging as a Novel Therapeutic Target to Reduce the Burden of Cardiovascular Disease?
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2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.
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Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.
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A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.