A citation-based method for searching scientific literature

Thomas M Ashton, W Gillies McKenna, Leoni A Kunz-Schughart, Geoff S Higgins. Clin Cancer Res 2018
Times Cited: 304







List of co-cited articles
924 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


An inhibitor of oxidative phosphorylation exploits cancer vulnerability.
Jennifer R Molina, Yuting Sun, Marina Protopopova, Sonal Gera, Madhavi Bandi, Christopher Bristow, Timothy McAfoos, Pietro Morlacchi, Jeffrey Ackroyd, Ahmed-Noor A Agip,[...]. Nat Med 2018
321
20

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
15

On the origin of cancer cells.
O WARBURG. Science 1956
14

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
13

Mitochondrial metabolism and cancer.
Paolo Ettore Porporato, Nicoletta Filigheddu, José Manuel Bravo-San Pedro, Guido Kroemer, Lorenzo Galluzzi. Cell Res 2018
409
12

Targeting mitochondria metabolism for cancer therapy.
Samuel E Weinberg, Navdeep S Chandel. Nat Chem Biol 2015
747
11

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis.
Valerie S LeBleu, Joyce T O'Connell, Karina N Gonzalez Herrera, Harriet Wikman, Klaus Pantel, Marcia C Haigis, Fernanda Machado de Carvalho, Aline Damascena, Ludmilla Thome Domingos Chinen, Rafael M Rocha,[...]. Nat Cell Biol 2014
728
10

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis.
William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, Gr Scott Budigner,[...]. Elife 2014
607
10

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells.
Michalina Janiszewska, Mario L Suvà, Nicolo Riggi, Riekelt H Houtkooper, Johan Auwerx, Virginie Clément-Schatlo, Ivan Radovanovic, Esther Rheinbay, Paolo Provero, Ivan Stamenkovic. Genes Dev 2012
271
10

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
10

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia.
Thomas M Ashton, Emmanouil Fokas, Leoni A Kunz-Schughart, Lisa K Folkes, Selvakumar Anbalagan, Melanie Huether, Catherine J Kelly, Giacomo Pirovano, Francesca M Buffa, Ester M Hammond,[...]. Nat Commun 2016
103
9

The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
9

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
8

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.
Marko Skrtić, Shrivani Sriskanthadevan, Bozhena Jhas, Marinella Gebbia, Xiaoming Wang, Zezhou Wang, Rose Hurren, Yulia Jitkova, Marcela Gronda, Neil Maclean,[...]. Cancer Cell 2011
396
8

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
8

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Andrea Viale, Piergiorgio Pettazzoni, Costas A Lyssiotis, Haoqiang Ying, Nora Sánchez, Matteo Marchesini, Alessandro Carugo, Tessa Green, Sahil Seth, Virginia Giuliani,[...]. Nature 2014
706
8

Cancer metabolism: facts, fantasy, and fiction.
Xin Lin Zu, Michael Guppy. Biochem Biophys Res Commun 2004
414
8

Mitochondrial DNA copy number variation across human cancers.
Ed Reznik, Martin L Miller, Yasin Şenbabaoğlu, Nadeem Riaz, Judy Sarungbam, Satish K Tickoo, Hikmat A Al-Ahmadie, William Lee, Venkatraman E Seshan, A Ari Hakimi,[...]. Elife 2016
240
7

Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.
Rizwan Haq, Jonathan Shoag, Pedro Andreu-Perez, Satoru Yokoyama, Hannah Edelman, Glenn C Rowe, Dennie T Frederick, Aeron D Hurley, Abhinav Nellore, Andrew L Kung,[...]. Cancer Cell 2013
538
7

PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.
Francisca Vazquez, Ji-Hong Lim, Helen Chim, Kavita Bhalla, Geoff Girnun, Kerry Pierce, Clary B Clish, Scott R Granter, Hans R Widlund, Bruce M Spiegelman,[...]. Cancer Cell 2013
456
7

Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization.
Lisha Xiang, Jun Mou, Bin Shao, Yuquan Wei, Houjie Liang, Naoharu Takano, Gregg L Semenza, Ganfeng Xie. Cell Death Dis 2019
60
11

Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Matt I Gross, Susan D Demo, Jennifer B Dennison, Lijing Chen, Tania Chernov-Rogan, Bindu Goyal, Julie R Janes, Guy J Laidig, Evan R Lewis, Jim Li,[...]. Mol Cancer Ther 2014
525
7

BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.
Eleni D Lagadinou, Alexander Sach, Kevin Callahan, Randall M Rossi, Sarah J Neering, Mohammad Minhajuddin, John M Ashton, Shanshan Pei, Valerie Grose, Kristen M O'Dwyer,[...]. Cell Stem Cell 2013
706
7

Metabolic reprogramming and cancer progression.
Brandon Faubert, Ashley Solmonson, Ralph J DeBerardinis. Science 2020
309
7

Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
908
7

Reprogramming of fatty acid metabolism in cancer.
Nikos Koundouros, George Poulogiannis. Br J Cancer 2020
254
7

Repurposing atovaquone: targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells.
Marco Fiorillo, Rebecca Lamb, Herbert B Tanowitz, Luciano Mutti, Marija Krstic-Demonacos, Anna Rita Cappello, Ubaldo E Martinez-Outschoorn, Federica Sotgia, Michael P Lisanti. Oncotarget 2016
117
7

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
6



Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA.
An S Tan, James W Baty, Lan-Feng Dong, Ayenachew Bezawork-Geleta, Berwini Endaya, Jacob Goodwin, Martina Bajzikova, Jaromira Kovarova, Martin Peterka, Bing Yan,[...]. Cell Metab 2015
408
6


Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
David R Wise, Ralph J DeBerardinis, Anthony Mancuso, Nabil Sayed, Xiao-Yong Zhang, Harla K Pfeiffer, Ilana Nissim, Evgueni Daikhin, Marc Yudkoff, Steven B McMahon,[...]. Proc Natl Acad Sci U S A 2008
6

Metabolic Heterogeneity in Human Lung Tumors.
Christopher T Hensley, Brandon Faubert, Qing Yuan, Naama Lev-Cohain, Eunsook Jin, Jiyeon Kim, Lei Jiang, Bookyung Ko, Rachael Skelton, Laurin Loudat,[...]. Cell 2016
555
6

TIGAR, a p53-inducible regulator of glycolysis and apoptosis.
Karim Bensaad, Atsushi Tsuruta, Mary A Selak, M Nieves Calvo Vidal, Katsunori Nakano, Ramon Bartrons, Eyal Gottlieb, Karen H Vousden. Cell 2006
6

Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
6

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
6

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel. Proc Natl Acad Sci U S A 2010
6

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria.
Hannah R Bridges, Andrew J Y Jones, Michael N Pollak, Judy Hirst. Biochem J 2014
384
6

From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
732
6

Why All the Fuss about Oxidative Phosphorylation (OXPHOS)?
Yibin Xu, Ding Xue, Armand Bankhead, Nouri Neamati. J Med Chem 2020
13
46

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.
Patricia Sancho, Emma Burgos-Ramos, Alejandra Tavera, Tony Bou Kheir, Petra Jagust, Matthieu Schoenhals, David Barneda, Katherine Sellers, Ramon Campos-Olivas, Osvaldo Graña,[...]. Cell Metab 2015
398
6

Mitochondria and Cancer.
Wei-Xing Zong, Joshua D Rabinowitz, Eileen White. Mol Cell 2016
451
6

The multifaceted roles of fatty acid synthesis in cancer.
Florian Röhrig, Almut Schulze. Nat Rev Cancer 2016
537
6

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
5

The Mitochondrial Complex(I)ty of Cancer.
Félix A Urra, Felipe Muñoz, Alenka Lovy, César Cárdenas. Front Oncol 2017
72
6

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.
Lucas B Sullivan, Dan Y Gui, Aaron M Hosios, Lauren N Bush, Elizaveta Freinkman, Matthew G Vander Heiden. Cell 2015
551
5

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
994
5

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Jason W Locasale, Alexandra R Grassian, Tamar Melman, Costas A Lyssiotis, Katherine R Mattaini, Adam J Bass, Gregory Heffron, Christian M Metallo, Taru Muranen, Hadar Sharfi,[...]. Nat Genet 2011
714
5

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.