A citation-based method for searching scientific literature

Ricardo Leão, Joana Dias Apolónio, Donghyun Lee, Arnaldo Figueiredo, Uri Tabori, Pedro Castelo-Branco. J Biomed Sci 2018
Times Cited: 74







List of co-cited articles
646 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
21

Highly recurrent TERT promoter mutations in human melanoma.
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
20

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
20

TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
18


Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies.
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
212
17

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
848
14

Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
201
14

Frequency of TERT promoter mutations in human cancers.
João Vinagre, Ana Almeida, Helena Pópulo, Rui Batista, Joana Lyra, Vasco Pinto, Ricardo Coelho, Ricardo Celestino, Hugo Prazeres, Luis Lima,[...]. Nat Commun 2013
512
14

Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.
Pedro Castelo-Branco, Sanaa Choufani, Stephen Mack, Denis Gallagher, Cindy Zhang, Tatiana Lipman, Nataliya Zhukova, Erin J Walker, Dianna Martin, Diana Merino,[...]. Lancet Oncol 2013
148
12

Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene.
Muhammad Khairul Ramlee, Jing Wang, Wei Xun Toh, Shang Li. Genes (Basel) 2016
70
12

Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism.
Kunitoshi Chiba, Franziska K Lorbeer, A Hunter Shain, David T McSwiggen, Eva Schruf, Areum Oh, Jekwan Ryu, Xavier Darzacq, Boris C Bastian, Dirk Hockemeyer. Science 2017
121
10

Reactivation of telomerase in cancer.
Semih Can Akincilar, Bilal Unal, Vinay Tergaonkar. Cell Mol Life Sci 2016
80
10

Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate.
Emanuelle Pascolo, Christian Wenz, Joachim Lingner, Norbert Hauel, Henning Priepke, Iris Kauffmann, Pilar Garin-Chesa, Wolfgang J Rettig, Klaus Damm, Andreas Schnapp. J Biol Chem 2002
187
10


Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity.
Isabelle Guilleret, Pu Yan, Fabienne Grange, Richard Braunschweig, Fred T Bosman, Jean Benhattar. Int J Cancer 2002
173
10

Therapeutic Targeting of Telomerase.
Kathrin Jäger, Michael Walter. Genes (Basel) 2016
61
11



DNA hypermethylation within TERT promoter upregulates TERT expression in cancer.
Donghyun D Lee, Ricardo Leão, Martin Komosa, Marco Gallo, Cindy H Zhang, Tatiana Lipman, Marc Remke, Abolfazl Heidari, Nuno Miguel Nunes, Joana D Apolónio,[...]. J Clin Invest 2019
43
16

Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.
Robert J A Bell, H Tomas Rube, Alex Kreig, Andrew Mancini, Shaun D Fouse, Raman P Nagarajan, Serah Choi, Chibo Hong, Daniel He, Melike Pekmezci,[...]. Science 2015
287
8

A randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced non-small-cell lung cancer.
A A Chiappori, T Kolevska, D R Spigel, S Hager, M Rarick, S Gadgeel, N Blais, J Von Pawel, L Hart, M Reck,[...]. Ann Oncol 2015
85
8


A survey of telomerase activity in human cancer.
J W Shay, S Bacchetti. Eur J Cancer 1997
8

Treating Cancer by Targeting Telomeres and Telomerase.
Marko Ivancich, Zachary Schrank, Luke Wojdyla, Brandon Leviskas, Adijan Kuckovic, Ankita Sanjali, Neelu Puri. Antioxidants (Basel) 2017
48
12

Human telomerase and its regulation.
Yu-Sheng Cong, Woodring E Wright, Jerry W Shay. Microbiol Mol Biol Rev 2002
586
8

Novel anticancer therapeutics targeting telomerase.
Maria Ruden, Neelu Puri. Cancer Treat Rev 2013
188
8



Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers.
Satoru Kyo, Masahiro Takakura, Toshiyoshi Fujiwara, Masaki Inoue. Cancer Sci 2008
243
8

TERT promoter mutations in telomere biology.
Barbara Heidenreich, Rajiv Kumar. Mutat Res Rev Mutat Res 2017
76
8

Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers.
Josh Lewis Stern, Dan Theodorescu, Bert Vogelstein, Nickolas Papadopoulos, Thomas R Cech. Genes Dev 2015
97
8

A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study.
Pedro Castelo-Branco, Ricardo Leão, Tatiana Lipman, Brittany Campbell, Donghyun Lee, Aryeh Price, Cindy Zhang, Abolfazl Heidari, Derek Stephens, Stefan Boerno,[...]. Oncotarget 2016
37
16

Telomerase directly regulates NF-κB-dependent transcription.
Arkasubhra Ghosh, Gaye Saginc, Shi Chi Leow, Ekta Khattar, Eun Myong Shin, Ting Dong Yan, Marc Wong, Zhizhuo Zhang, Guoliang Li, Wing-Kin Sung,[...]. Nat Cell Biol 2012
208
8


Alternative Splicing of hTERT Pre-mRNA: A Potential Strategy for the Regulation of Telomerase Activity.
Xuewen Liu, Yuchuan Wang, Guangming Chang, Feng Wang, Fei Wang, Xin Geng. Int J Mol Sci 2017
19
26

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
6

The RNA component of human telomerase.
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
6

Telomere Maintenance Mechanisms in Cancer.
Tiago Bordeira Gaspar, Ana Sá, José Manuel Lopes, Manuel Sobrinho-Simões, Paula Soares, João Vinagre. Genes (Basel) 2018
43
11


How shelterin protects mammalian telomeres.
Wilhelm Palm, Titia de Lange. Annu Rev Genet 2008
6


Induction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2'-deoxyguanosine.
Ilgen Mender, Sergei Gryaznov, Z Gunnur Dikmen, Woodring E Wright, Jerry W Shay. Cancer Discov 2015
58
8

Telomerase activity in human germline and embryonic tissues and cells.
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
951
6


The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis.
Imke Listerman, Jie Sun, Francesca S Gazzaniga, Jason L Lukas, Elizabeth H Blackburn. Cancer Res 2013
98
6

TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism.
P Sivaramakrishna Rachakonda, Ismail Hosen, Petra J de Verdier, Mahdi Fallah, Barbara Heidenreich, Charlotta Ryk, N Peter Wiklund, Gunnar Steineck, Dirk Schadendorf, Kari Hemminki,[...]. Proc Natl Acad Sci U S A 2013
209
6



Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging.
Elizabeth H Blackburn, Carol W Greider, Jack W Szostak. Nat Med 2006
562
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.