A citation-based method for searching scientific literature

N J Haradhvala, J Kim, Y E Maruvka, P Polak, D Rosebrock, D Livitz, J M Hess, I Leshchiner, A Kamburov, K W Mouw, M S Lawrence, G Getz. Nat Commun 2018
Times Cited: 80







List of co-cited articles
677 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Signatures of mutational processes in human cancer.
Ludmil B Alexandrov, Serena Nik-Zainal, David C Wedge, Samuel A J R Aparicio, Sam Behjati, Andrew V Biankin, Graham R Bignell, Niccolò Bolli, Ake Borg, Anne-Lise Børresen-Dale,[...]. Nature 2013
61

The repertoire of mutational signatures in human cancer.
Ludmil B Alexandrov, Jaegil Kim, Nicholas J Haradhvala, Mi Ni Huang, Alvin Wei Tian Ng, Yang Wu, Arnoud Boot, Kyle R Covington, Dmitry A Gordenin, Erik N Bergstrom,[...]. Nature 2020
774
36

Comprehensive Analysis of Hypermutation in Human Cancer.
Brittany B Campbell, Nicholas Light, David Fabrizio, Matthew Zatzman, Fabio Fuligni, Richard de Borja, Scott Davidson, Melissa Edwards, Julia A Elvin, Karl P Hodel,[...]. Cell 2017
397
31

Deciphering signatures of mutational processes operative in human cancer.
Ludmil B Alexandrov, Serena Nik-Zainal, David C Wedge, Peter J Campbell, Michael R Stratton. Cell Rep 2013
654
27

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.
Claire Palles, Jean-Baptiste Cazier, Kimberley M Howarth, Enric Domingo, Angela M Jones, Peter Broderick, Zoe Kemp, Sarah L Spain, Estrella Guarino, Israel Salguero,[...]. Nat Genet 2013
619
25

Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication.
Eve Shinbrot, Erin E Henninger, Nils Weinhold, Kyle R Covington, A Yasemin Göksenin, Nikolaus Schultz, Hsu Chao, HarshaVardhan Doddapaneni, Donna M Muzny, Richard A Gibbs,[...]. Genome Res 2014
173
23

Integrated genomic characterization of endometrial carcinoma.
Cyriac Kandoth, Nikolaus Schultz, Andrew D Cherniack, Rehan Akbani, Yuexin Liu, Hui Shen, A Gordon Robertson, Itai Pashtan, Ronglai Shen, Christopher C Benz,[...]. Nature 2013
23

Validating the concept of mutational signatures with isogenic cell models.
Xueqing Zou, Michel Owusu, Rebecca Harris, Stephen P Jackson, Joanna I Loizou, Serena Nik-Zainal. Nat Commun 2018
71
26

DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution.
Rachel Rosenthal, Nicholas McGranahan, Javier Herrero, Barry S Taylor, Charles Swanton. Genome Biol 2016
538
18

Mutational processes molding the genomes of 21 breast cancers.
Serena Nik-Zainal, Ludmil B Alexandrov, David C Wedge, Peter Van Loo, Christopher D Greenman, Keiran Raine, David Jones, Jonathan Hinton, John Marshall, Lucy A Stebbings,[...]. Cell 2012
18

Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer.
Jarno Drost, Ruben van Boxtel, Francis Blokzijl, Tomohiro Mizutani, Nobuo Sasaki, Valentina Sasselli, Joep de Ligt, Sam Behjati, Judith E Grolleman, Tom van Wezel,[...]. Science 2017
220
18

Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors.
Jaegil Kim, Kent W Mouw, Paz Polak, Lior Z Braunstein, Atanas Kamburov, David J Kwiatkowski, Jonathan E Rosenberg, Eliezer M Van Allen, Alan D'Andrea, Gad Getz. Nat Genet 2016
204
18

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.
Serena Nik-Zainal, Helen Davies, Johan Staaf, Manasa Ramakrishna, Dominik Glodzik, Xueqing Zou, Inigo Martincorena, Ludmil B Alexandrov, Sancha Martin, David C Wedge,[...]. Nature 2016
17

A panoply of errors: polymerase proofreading domain mutations in cancer.
Emily Rayner, Inge C van Gool, Claire Palles, Stephen E Kearsey, Tjalling Bosse, Ian Tomlinson, David N Church. Nat Rev Cancer 2016
196
16

The topography of mutational processes in breast cancer genomes.
Sandro Morganella, Ludmil B Alexandrov, Dominik Glodzik, Xueqing Zou, Helen Davies, Johan Staaf, Anieta M Sieuwerts, Arie B Brinkman, Sancha Martin, Manasa Ramakrishna,[...]. Nat Commun 2016
149
16


DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer.
David N Church, Sarah E W Briggs, Claire Palles, Enric Domingo, Stephen J Kearsey, Jonathon M Grimes, Maggie Gorman, Lynn Martin, Kimberley M Howarth, Shirley V Hodgson,[...]. Hum Mol Genet 2013
220
16

Clock-like mutational processes in human somatic cells.
Ludmil B Alexandrov, Philip H Jones, David C Wedge, Julian E Sale, Peter J Campbell, Serena Nik-Zainal, Michael R Stratton. Nat Genet 2015
470
15

Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.
Camilla Pilati, Jayendra Shinde, Ludmil B Alexandrov, Guillaume Assié, Thierry André, Zofia Hélias-Rodzewicz, Romain Ducoudray, Delphine Le Corre, Jessica Zucman-Rossi, Jean-François Emile,[...]. J Pathol 2017
75
16

A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme.
Xuanxuan Xing, Daniel P Kane, Chelsea R Bulock, Elizabeth A Moore, Sushma Sharma, Andrei Chabes, Polina V Shcherbakova. Nat Commun 2019
30
40

Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers.
Bettina Meier, Nadezda V Volkova, Ye Hong, Pieta Schofield, Peter J Campbell, Moritz Gerstung, Anton Gartner. Genome Res 2018
49
24

Mutational signatures associated with tobacco smoking in human cancer.
Ludmil B Alexandrov, Young Seok Ju, Kerstin Haase, Peter Van Loo, Iñigo Martincorena, Serena Nik-Zainal, Yasushi Totoki, Akihiro Fujimoto, Hidewaki Nakagawa, Tatsuhiro Shibata,[...]. Science 2016
498
13

A Compendium of Mutational Signatures of Environmental Agents.
Jill E Kucab, Xueqing Zou, Sandro Morganella, Madeleine Joel, A Scott Nanda, Eszter Nagy, Celine Gomez, Andrea Degasperi, Rebecca Harris, Stephen P Jackson,[...]. Cell 2019
203
13

COSMIC: the Catalogue Of Somatic Mutations In Cancer.
John G Tate, Sally Bamford, Harry C Jubb, Zbyslaw Sondka, David M Beare, Nidhi Bindal, Harry Boutselakis, Charlotte G Cole, Celestino Creatore, Elisabeth Dawson,[...]. Nucleic Acids Res 2019
13


A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer.
Paz Polak, Jaegil Kim, Lior Z Braunstein, Rosa Karlic, Nicholas J Haradhavala, Grace Tiao, Daniel Rosebrock, Dimitri Livitz, Kirsten Kübler, Kent W Mouw,[...]. Nat Genet 2017
255
12

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.
Nicholas J Haradhvala, Paz Polak, Petar Stojanov, Kyle R Covington, Eve Shinbrot, Julian M Hess, Esther Rheinbay, Jaegil Kim, Yosef E Maruvka, Lior Z Braunstein,[...]. Cell 2016
209
12

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.
Ethan Cerami, Jianjiong Gao, Ugur Dogrusoz, Benjamin E Gross, Selcuk Onur Sumer, Bülent Arman Aksoy, Anders Jacobsen, Caitlin J Byrne, Michael L Heuer, Erik Larsson,[...]. Cancer Discov 2012
12

A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.
Alessandra Viel, Alessandro Bruselles, Ettore Meccia, Mara Fornasarig, Michele Quaia, Vincenzo Canzonieri, Eleonora Policicchio, Emanuele Damiano Urso, Marco Agostini, Maurizio Genuardi,[...]. EBioMedicine 2017
98
12


DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.
Tina M Albertson, Masanori Ogawa, James M Bugni, Laura E Hays, Yang Chen, Yanping Wang, Piper M Treuting, John A Heddle, Robert E Goldsby, Bradley D Preston. Proc Natl Acad Sci U S A 2009
154
11

Mutational heterogeneity in cancer and the search for new cancer-associated genes.
Michael S Lawrence, Petar Stojanov, Paz Polak, Gregory V Kryukov, Kristian Cibulskis, Andrey Sivachenko, Scott L Carter, Chip Stewart, Craig H Mermel, Steven A Roberts,[...]. Nature 2013
11

Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers.
Anne Ml Jansen, Tom van Wezel, Brendy Ewm van den Akker, Marina Ventayol Garcia, Dina Ruano, Carli Mj Tops, Anja Wagner, Tom Gw Letteboer, Encarna B Gómez-García, Peter Devilee,[...]. Eur J Hum Genet 2016
84
11

POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance.
Fernando Bellido, Marta Pineda, Gemma Aiza, Rafael Valdés-Mas, Matilde Navarro, Diana A Puente, Tirso Pons, Sara González, Silvia Iglesias, Esther Darder,[...]. Genet Med 2016
145
11

Mechanisms underlying mutational signatures in human cancers.
Thomas Helleday, Saeed Eshtad, Serena Nik-Zainal. Nat Rev Genet 2014
475
11

Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution.
S Kasar, J Kim, R Improgo, G Tiao, P Polak, N Haradhvala, M S Lawrence, A Kiezun, S M Fernandes, S Bahl,[...]. Nat Commun 2015
125
11

Mutational signatures: the patterns of somatic mutations hidden in cancer genomes.
Ludmil B Alexandrov, Michael R Stratton. Curr Opin Genet Dev 2014
271
11

Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer.
Janice M Mehnert, Anshuman Panda, Hua Zhong, Kim Hirshfield, Sherri Damare, Katherine Lane, Levi Sokol, Mark N Stein, Lorna Rodriguez-Rodriquez, Howard L Kaufman,[...]. J Clin Invest 2016
236
11

In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors.
Arnoud Boot, Mi Ni Huang, Alvin W T Ng, Szu-Chi Ho, Jing Quan Lim, Yoshiiku Kawakami, Kazuaki Chayama, Bin Tean Teh, Hidewaki Nakagawa, Steven G Rozen. Genome Res 2018
71
12

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.
Helen Davies, Dominik Glodzik, Sandro Morganella, Lucy R Yates, Johan Staaf, Xueqing Zou, Manasa Ramakrishna, Sancha Martin, Sandrine Boyault, Anieta M Sieuwerts,[...]. Nat Med 2017
408
11

Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis.
Mia Petljak, Ludmil B Alexandrov, Jonathan S Brammeld, Stacey Price, David C Wedge, Sebastian Grossmann, Kevin J Dawson, Young Seok Ju, Francesco Iorio, Jose M C Tubio,[...]. Cell 2019
146
11

EMu: probabilistic inference of mutational processes and their localization in the cancer genome.
Andrej Fischer, Christopher J R Illingworth, Peter J Campbell, Ville Mustonen. Genome Biol 2013
64
14

signeR: an empirical Bayesian approach to mutational signature discovery.
Rafael A Rosales, Rodrigo D Drummond, Renan Valieris, Emmanuel Dias-Neto, Israel T da Silva. Bioinformatics 2017
50
18

A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures.
Yuichi Shiraishi, Georg Tremmel, Satoru Miyano, Matthew Stephens. PLoS Genet 2015
71
12


PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.
Dung T Le, Jennifer N Uram, Hao Wang, Bjarne R Bartlett, Holly Kemberling, Aleksandra D Eyring, Andrew D Skora, Brandon S Luber, Nilofer S Azad, Dan Laheru,[...]. N Engl J Med 2015
11


Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae.
Stephanie R Barbari, Daniel P Kane, Elizabeth A Moore, Polina V Shcherbakova. G3 (Bethesda) 2018
27
29

Eukaryotic Mismatch Repair in Relation to DNA Replication.
Thomas A Kunkel, Dorothy A Erie. Annu Rev Genet 2015
207
10

Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load.
Hao-Dong Li, Ileana Cuevas, Musi Zhang, Changzheng Lu, Md Maksudul Alam, Yang-Xin Fu, M James You, Esra A Akbay, He Zhang, Diego H Castrillon. J Clin Invest 2018
35
22


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.