A citation-based method for searching scientific literature

Montserrat Rojo de la Vega, Eli Chapman, Donna D Zhang. Cancer Cell 2018
Times Cited: 419







List of co-cited articles
937 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
Gina M DeNicola, Florian A Karreth, Timothy J Humpton, Aarthi Gopinathan, Cong Wei, Kristopher Frese, Dipti Mangal, Kenneth H Yu, Charles J Yeo, Eric S Calhoun,[...]. Nature 2011
21

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
19

Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1.
Luca Lignitto, Sarah E LeBoeuf, Harrison Homer, Shaowen Jiang, Manor Askenazi, Triantafyllia R Karakousi, Harvey I Pass, Arjun J Bhutkar, Aristotelis Tsirigos, Beatrix Ueberheide,[...]. Cell 2019
182
18

Ferroptosis: an iron-dependent form of nonapoptotic cell death.
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
18

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.
Brent R Stockwell, José Pedro Friedmann Angeli, Hülya Bayir, Ashley I Bush, Marcus Conrad, Scott J Dixon, Simone Fulda, Sergio Gascón, Stavroula K Hatzios, Valerian E Kagan,[...]. Cell 2017
16

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Masaaki Komatsu, Hirofumi Kurokawa, Satoshi Waguri, Keiko Taguchi, Akira Kobayashi, Yoshinobu Ichimura, Yu-Shin Sou, Izumi Ueno, Ayako Sakamoto, Kit I Tong,[...]. Nat Cell Biol 2010
14

Regulation of ferroptotic cancer cell death by GPX4.
Wan Seok Yang, Rohitha SriRamaratnam, Matthew E Welsch, Kenichi Shimada, Rachid Skouta, Vasanthi S Viswanathan, Jaime H Cheah, Paul A Clemons, Alykhan F Shamji, Clary B Clish,[...]. Cell 2014
13

The Dual Roles of NRF2 in Cancer.
Silvia Menegon, Amedeo Columbano, Silvia Giordano. Trends Mol Med 2016
313
13

The emerging role of the Nrf2-Keap1 signaling pathway in cancer.
Melba C Jaramillo, Donna D Zhang. Genes Dev 2013
717
11

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain.
K Itoh, N Wakabayashi, Y Katoh, T Ishii, K Igarashi, J D Engel, M Yamamoto. Genes Dev 1999
11

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism.
John D Hayes, Albena T Dinkova-Kostova. Trends Biochem Sci 2014
982
11

Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Yoichiro Mitsuishi, Keiko Taguchi, Yukie Kawatani, Tatsuhiro Shibata, Toshihiro Nukiwa, Hiroyuki Aburatani, Masayuki Yamamoto, Hozumi Motohashi. Cancer Cell 2012
771
11

Nrf2 in cancers: A double-edged sword.
Shijia Wu, Hong Lu, Yongheng Bai. Cancer Med 2019
115
11

NRF2 and cancer: the good, the bad and the importance of context.
Michael B Sporn, Karen T Liby. Nat Rev Cancer 2012
643
10

Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors.
Anju Singh, Sreedhar Venkannagari, Kyu H Oh, Ya-Qin Zhang, Jason M Rohde, Li Liu, Sridhar Nimmagadda, Kuladeep Sudini, Kyle R Brimacombe, Sachin Gajghate,[...]. ACS Chem Biol 2016
193
10


The KEAP1-NRF2 System in Cancer.
Keiko Taguchi, Masayuki Yamamoto. Front Oncol 2017
190
10

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases.
Antonio Cuadrado, Ana I Rojo, Geoffrey Wells, John D Hayes, Sharon P Cousin, William L Rumsey, Otis C Attucks, Stephen Franklin, Anna-Liisa Levonen, Thomas W Kensler,[...]. Nat Rev Drug Discov 2019
357
10

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis.
Scott J Dixon, Darpan N Patel, Matthew Welsch, Rachid Skouta, Eric D Lee, Miki Hayano, Ajit G Thomas, Caroline E Gleason, Nicholas P Tatonetti, Barbara S Slusher,[...]. Elife 2014
586
10

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham, Jerome Alexandre, Peng Huang. Nat Rev Drug Discov 2009
10

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
Sebastian Doll, Bettina Proneth, Yulia Y Tyurina, Elena Panzilius, Sho Kobayashi, Irina Ingold, Martin Irmler, Johannes Beckers, Michaela Aichler, Axel Walch,[...]. Nat Chem Biol 2017
683
10

Modulating NRF2 in Disease: Timing Is Everything.
Matthew Dodson, Montserrat Rojo de la Vega, Aram B Cholanians, Cody J Schmidlin, Eli Chapman, Donna D Zhang. Annu Rev Pharmacol Toxicol 2019
105
10

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.
Kirill Bersuker, Joseph M Hendricks, Zhipeng Li, Leslie Magtanong, Breanna Ford, Peter H Tang, Melissa A Roberts, Bingqi Tong, Thomas J Maimone, Roberto Zoncu,[...]. Nature 2019
462
9

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.
Vasanthi S Viswanathan, Matthew J Ryan, Harshil D Dhruv, Shubhroz Gill, Ossia M Eichhoff, Brinton Seashore-Ludlow, Samuel D Kaffenberger, John K Eaton, Kenichi Shimada, Andrew J Aguirre,[...]. Nature 2017
478
9

NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction.
Chao Zhang, Hui-Jie Wang, Qi-Chao Bao, Lei Wang, Tian-Kun Guo, Wei-Lin Chen, Li-Li Xu, Hai-Shan Zhou, Jin-Lei Bian, Ying-Rui Yang,[...]. Oncotarget 2016
68
13

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.
Valerian E Kagan, Gaowei Mao, Feng Qu, Jose Pedro Friedmann Angeli, Sebastian Doll, Claudette St Croix, Haider Hussain Dar, Bing Liu, Vladimir A Tyurin, Vladimir B Ritov,[...]. Nat Chem Biol 2017
583
9

FSP1 is a glutathione-independent ferroptosis suppressor.
Sebastian Doll, Florencio Porto Freitas, Ron Shah, Maceler Aldrovandi, Milene Costa da Silva, Irina Ingold, Andrea Goya Grocin, Thamara Nishida Xavier da Silva, Elena Panzilius, Christina H Scheel,[...]. Nature 2019
463
9

Oxidative Stress in Cancer.
John D Hayes, Albena T Dinkova-Kostova, Kenneth D Tew. Cancer Cell 2020
183
9

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.
Anju Singh, Vikas Misra, Rajesh K Thimmulappa, Hannah Lee, Stephen Ames, Mohammad O Hoque, James G Herman, Stephen B Baylin, David Sidransky, Edward Gabrielson,[...]. PLoS Med 2006
733
9

Transcriptional Regulation by Nrf2.
Claudia Tonelli, Iok In Christine Chio, David A Tuveson. Antioxid Redox Signal 2018
494
9

Oncogenic KRAS confers chemoresistance by upregulating NRF2.
Shasha Tao, Shue Wang, Seyed Javad Moghaddam, Aikseng Ooi, Eli Chapman, Pak K Wong, Donna D Zhang. Cancer Res 2014
173
8

Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis.
Z Fan, A-K Wirth, D Chen, C J Wruck, M Rauh, M Buchfelder, N Savaskan. Oncogenesis 2017
169
8

NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis.
Hui Wang, Xiufei Liu, Min Long, Yi Huang, Linlin Zhang, Rui Zhang, Yi Zheng, Xiaoyu Liao, Yuren Wang, Qian Liao,[...]. Sci Transl Med 2016
138
8

Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.
Tsutomu Ohta, Kumiko Iijima, Mamiko Miyamoto, Izumi Nakahara, Hiroshi Tanaka, Makiko Ohtsuji, Takafumi Suzuki, Akira Kobayashi, Jun Yokota, Tokuki Sakiyama,[...]. Cancer Res 2008
453
8

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants.
Albena T Dinkova-Kostova, W David Holtzclaw, Robert N Cole, Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh, Masayuki Yamamoto, Paul Talalay. Proc Natl Acad Sci U S A 2002
8

Molecular basis of the Keap1-Nrf2 system.
Takafumi Suzuki, Masayuki Yamamoto. Free Radic Biol Med 2015
471
8

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
K Itoh, T Chiba, S Takahashi, T Ishii, K Igarashi, Y Katoh, T Oyake, N Hayashi, K Satoh, I Hatayama,[...]. Biochem Biophys Res Commun 1997
8

SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.
Patricia Rada, Ana I Rojo, Sudhir Chowdhry, Michael McMahon, John D Hayes, Antonio Cuadrado. Mol Cell Biol 2011
443
8

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.
Jose Pedro Friedmann Angeli, Manuela Schneider, Bettina Proneth, Yulia Y Tyurina, Vladimir A Tyurin, Victoria J Hammond, Nadja Herbach, Michaela Aichler, Axel Walch, Elke Eggenhofer,[...]. Nat Cell Biol 2014
915
8

Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Michael A Badgley, Daniel M Kremer, H Carlo Maurer, Kathleen E DelGiorno, Ho-Joon Lee, Vinee Purohit, Irina R Sagalovskiy, Alice Ma, Jonathan Kapilian, Christina E M Firl,[...]. Science 2020
180
8

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy.
Weimin Wang, Michael Green, Jae Eun Choi, Miguel Gijón, Paul D Kennedy, Jeffrey K Johnson, Peng Liao, Xueting Lang, Ilona Kryczek, Amanda Sell,[...]. Nature 2019
417
8

Targeting Ferroptosis to Iron Out Cancer.
Behrouz Hassannia, Peter Vandenabeele, Tom Vanden Berghe. Cancer Cell 2019
354
8

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells.
Xiaofang Sun, Zhanhui Ou, Ruochan Chen, Xiaohua Niu, De Chen, Rui Kang, Daolin Tang. Hepatology 2016
518
8

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
Ashish Jain, Trond Lamark, Eva Sjøttem, Kenneth Bowitz Larsen, Jane Atesoh Awuh, Aud Øvervatn, Michael McMahon, John D Hayes, Terje Johansen. J Biol Chem 2010
848
8

Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response.
Weimin Chen, Zheng Sun, Xiao-Jun Wang, Tao Jiang, Zheping Huang, Deyu Fang, Donna D Zhang. Mol Cell 2009
405
8

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis.
Deepti Malhotra, Elodie Portales-Casamar, Anju Singh, Siddhartha Srivastava, David Arenillas, Christine Happel, Casper Shyr, Nobunao Wakabayashi, Thomas W Kensler, Wyeth W Wasserman,[...]. Nucleic Acids Res 2010
484
8

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis.
Masayuki Yamamoto, Thomas W Kensler, Hozumi Motohashi. Physiol Rev 2018
413
8

The Role of Nrf2 Activity in Cancer Development and Progression.
Alina-Andreea Zimta, Diana Cenariu, Alexandru Irimie, Lorand Magdo, Seyed Mohammad Nabavi, Atanas G Atanasov, Ioana Berindan-Neagoe. Cancers (Basel) 2019
65
12

A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.
Alexandria Lau, Xiao-Jun Wang, Fei Zhao, Nicole F Villeneuve, Tongde Wu, Tao Jiang, Zheng Sun, Eileen White, Donna D Zhang. Mol Cell Biol 2010
524
8

Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion.
José Pedro Friedmann Angeli, Dmitri V Krysko, Marcus Conrad. Nat Rev Cancer 2019
243
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.