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Times Cited: 52
Times Cited: 52
Times Cited
Times Co-cited
Similarity
The shieldin complex mediates 53BP1-dependent DNA repair.
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.
Harveer Dev, Ting-Wei Will Chiang, Chloe Lescale, Inge de Krijger, Alistair G Martin, Domenic Pilger, Julia Coates, Matylda Sczaniecka-Clift, Wenming Wei, Matthias Ostermaier,[...]. Nat Cell Biol 2018
Harveer Dev, Ting-Wei Will Chiang, Chloe Lescale, Inge de Krijger, Alistair G Martin, Domenic Pilger, Julia Coates, Matylda Sczaniecka-Clift, Wenming Wei, Matthias Ostermaier,[...]. Nat Cell Biol 2018
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DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig,[...]. Cell 2018
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig,[...]. Cell 2018
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53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in.
Zachary Mirman, Francisca Lottersberger, Hiroyuki Takai, Tatsuya Kibe, Yi Gong, Kaori Takai, Alessandro Bianchi, Michal Zimmermann, Daniel Durocher, Titia de Lange. Nature 2018
Zachary Mirman, Francisca Lottersberger, Hiroyuki Takai, Tatsuya Kibe, Yi Gong, Kaori Takai, Alessandro Bianchi, Michal Zimmermann, Daniel Durocher, Titia de Lange. Nature 2018
82
53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
Hind Ghezraoui, Catarina Oliveira, Jordan R Becker, Kirstin Bilham, Daniela Moralli, Consuelo Anzilotti, Roman Fischer, Mukta Deobagkar-Lele, Maria Sanchiz-Calvo, Elena Fueyo-Marcos,[...]. Nature 2018
Hind Ghezraoui, Catarina Oliveira, Jordan R Becker, Kirstin Bilham, Daniela Moralli, Consuelo Anzilotti, Roman Fischer, Mukta Deobagkar-Lele, Maria Sanchiz-Calvo, Elena Fueyo-Marcos,[...]. Nature 2018
80
REV7 counteracts DNA double-strand break resection and affects PARP inhibition.
Guotai Xu, J Ross Chapman, Inger Brandsma, Jingsong Yuan, Martin Mistrik, Peter Bouwman, Jirina Bartkova, Ewa Gogola, Daniël Warmerdam, Marco Barazas,[...]. Nature 2015
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MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.
Vera Boersma, Nathalie Moatti, Sandra Segura-Bayona, Marieke H Peuscher, Jaco van der Torre, Brigitte A Wevers, Alexandre Orthwein, Daniel Durocher, Jacqueline J L Jacobs. Nature 2015
Vera Boersma, Nathalie Moatti, Sandra Segura-Bayona, Marieke H Peuscher, Jaco van der Torre, Brigitte A Wevers, Alexandre Orthwein, Daniel Durocher, Jacqueline J L Jacobs. Nature 2015
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A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Cristina Escribano-Díaz, Alexandre Orthwein, Amélie Fradet-Turcotte, Mengtan Xing, Jordan T F Young, Ján Tkáč, Michael A Cook, Adam P Rosebrock, Meagan Munro, Marella D Canny,[...]. Mol Cell 2013
Cristina Escribano-Díaz, Alexandre Orthwein, Amélie Fradet-Turcotte, Mengtan Xing, Jordan T F Young, Ján Tkáč, Michael A Cook, Adam P Rosebrock, Meagan Munro, Marella D Canny,[...]. Mol Cell 2013
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RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.
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J Ross Chapman, Patricia Barral, Jean-Baptiste Vannier, Valérie Borel, Martin Steger, Antonia Tomas-Loba, Alessandro A Sartori, Ian R Adams, Facundo D Batista, Simon J Boulton. Mol Cell 2013
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53BP1 regulates DSB repair using Rif1 to control 5' end resection.
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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
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SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.
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Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
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An OB-fold complex controls the repair pathways for DNA double-strand breaks.
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The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.
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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
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53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
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53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.
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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
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BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.
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Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.
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DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.
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Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1.
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A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
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Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
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Non-homologous DNA end joining and alternative pathways to double-strand break repair.
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53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.
John P Manis, Julio C Morales, Zhenfang Xia, Jeffery L Kutok, Frederick W Alt, Phillip B Carpenter. Nat Immunol 2004
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53BP1 is required for class switch recombination.
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REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ.
Junya Tomida, Kei-ichi Takata, Sabine S Lange, Andria C Schibler, Matthew J Yousefzadeh, Sarita Bhetawal, Sharon Y R Dent, Richard D Wood. Nucleic Acids Res 2015
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Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex.
Alessandro A Rizzo, Faye-Marie Vassel, Nimrat Chatterjee, Sanjay D'Souza, Yunfeng Li, Bing Hao, Michael T Hemann, Graham C Walker, Dmitry M Korzhnev. Proc Natl Acad Sci U S A 2018
Alessandro A Rizzo, Faye-Marie Vassel, Nimrat Chatterjee, Sanjay D'Souza, Yunfeng Li, Bing Hao, Michael T Hemann, Graham C Walker, Dmitry M Korzhnev. Proc Natl Acad Sci U S A 2018
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TRIP13 regulates DNA repair pathway choice through REV7 conformational change.
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The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.
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53BP1 fosters fidelity of homology-directed DNA repair.
Fena Ochs, Kumar Somyajit, Matthias Altmeyer, Maj-Britt Rask, Jiri Lukas, Claudia Lukas. Nat Struct Mol Biol 2016
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The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity.
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Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP).
Kodai Hara, Shota Taharazako, Masanori Ikeda, Hiroki Fujita, Yoshiko Mikami, Sotaro Kikuchi, Asami Hishiki, Hideshi Yokoyama, Yoshinobu Ishikawa, Shin-Ichiro Kanno,[...]. J Biol Chem 2017
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Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase.
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RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.
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RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.
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TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.