Mahip K Verma, Rajan Goel, Nandakumar Krishnadas, Kumar V S Nemmani. Expert Opin Ther Targets 2018
Times Cited: 15
Times Cited: 15
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Pharmacology, physiology, and mechanisms of incretin hormone action.
Jonathan E Campbell, Daniel J Drucker. Cell Metab 2013
Jonathan E Campbell, Daniel J Drucker. Cell Metab 2013
53
Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial.
Dilan Athauda, Kate Maclagan, Simon S Skene, Martha Bajwa-Joseph, Dawn Letchford, Kashfia Chowdhury, Steve Hibbert, Natalia Budnik, Luca Zampedri, John Dickson,[...]. Lancet 2017
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Novel dual GLP-1/GIP receptor agonists show neuroprotective effects in Alzheimer's and Parkinson's disease models.
Christian Hölscher. Neuropharmacology 2018
Christian Hölscher. Neuropharmacology 2018
40
GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.
Yazhou Li, Kara B Duffy, Mary Ann Ottinger, Balmiki Ray, Jason A Bailey, Harold W Holloway, David Tweedie, Tracyann Perry, Mark P Mattson, Dimitrios Kapogiannis,[...]. J Alzheimers Dis 2010
Yazhou Li, Kara B Duffy, Mary Ann Ottinger, Balmiki Ray, Jason A Bailey, Harold W Holloway, David Tweedie, Tracyann Perry, Mark P Mattson, Dimitrios Kapogiannis,[...]. J Alzheimers Dis 2010
40
Glucose-dependent insulinotropic polypeptide is expressed in adult hippocampus and induces progenitor cell proliferation.
Jenny Nyberg, Michelle F Anderson, Björn Meister, Ann-Marie Alborn, Anna-Karin Ström, Anke Brederlau, Ann-Christin Illerskog, Ola Nilsson, Timothy J Kieffer, Max Albert Hietala,[...]. J Neurosci 2005
Jenny Nyberg, Michelle F Anderson, Björn Meister, Ann-Marie Alborn, Anna-Karin Ström, Anke Brederlau, Ann-Christin Illerskog, Ola Nilsson, Timothy J Kieffer, Max Albert Hietala,[...]. J Neurosci 2005
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In Alzheimer's Disease, 6-Month Treatment with GLP-1 Analog Prevents Decline of Brain Glucose Metabolism: Randomized, Placebo-Controlled, Double-Blind Clinical Trial.
Michael Gejl, Albert Gjedde, Lærke Egefjord, Arne Møller, Søren B Hansen, Kim Vang, Anders Rodell, Hans Brændgaard, Hanne Gottrup, Anna Schacht,[...]. Front Aging Neurosci 2016
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GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism.
Yazhou Li, TracyAnn Perry, Mark S Kindy, Brandon K Harvey, David Tweedie, Harold W Holloway, Kathleen Powers, Hui Shen, Josephine M Egan, Kumar Sambamurti,[...]. Proc Natl Acad Sci U S A 2009
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Exenatide and the treatment of patients with Parkinson's disease.
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33
33
Neuroprotective effects of a GIP analogue in the MPTP Parkinson's disease mouse model.
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Yanwei Li, WeiZhen Liu, Lin Li, Christian Hölscher. Neuropharmacology 2016
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Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease.
Sehee Kim, Minho Moon, Seungjoon Park. J Endocrinol 2009
Sehee Kim, Minho Moon, Seungjoon Park. J Endocrinol 2009
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Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease.
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26
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
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The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.
Paula L McClean, Vadivel Parthsarathy, Emilie Faivre, Christian Hölscher. J Neurosci 2011
Paula L McClean, Vadivel Parthsarathy, Emilie Faivre, Christian Hölscher. J Neurosci 2011
26
Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases.
Christian Hölscher. Biochem Soc Trans 2014
Christian Hölscher. Biochem Soc Trans 2014
26
Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial.
Juan Pablo Frias, Michael A Nauck, Joanna Van, Mark E Kutner, Xuewei Cui, Charles Benson, Shweta Urva, Ruth E Gimeno, Zvonko Milicevic, Deborah Robins,[...]. Lancet 2018
Juan Pablo Frias, Michael A Nauck, Joanna Van, Mark E Kutner, Xuewei Cui, Charles Benson, Shweta Urva, Ruth E Gimeno, Zvonko Milicevic, Deborah Robins,[...]. Lancet 2018
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Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.
Brian Finan, Tao Ma, Nickki Ottaway, Timo D Müller, Kirk M Habegger, Kristy M Heppner, Henriette Kirchner, Jenna Holland, Jazzminn Hembree, Christine Raver,[...]. Sci Transl Med 2013
Brian Finan, Tao Ma, Nickki Ottaway, Timo D Müller, Kirk M Habegger, Kristy M Heppner, Henriette Kirchner, Jenna Holland, Jazzminn Hembree, Christine Raver,[...]. Sci Transl Med 2013
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The Sustained Effects of a Dual GIP/GLP-1 Receptor Agonist, NNC0090-2746, in Patients with Type 2 Diabetes.
Juan Pablo Frias, Edward J Bastyr, Louis Vignati, Matthias H Tschöp, Christophe Schmitt, Klara Owen, Rune Haubo Christensen, Richard D DiMarchi. Cell Metab 2017
Juan Pablo Frias, Edward J Bastyr, Louis Vignati, Matthias H Tschöp, Christophe Schmitt, Klara Owen, Rune Haubo Christensen, Richard D DiMarchi. Cell Metab 2017
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Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain.
T B Usdin, E Mezey, D C Button, M J Brownstein, T I Bonner. Endocrinology 1993
T B Usdin, E Mezey, D C Button, M J Brownstein, T I Bonner. Endocrinology 1993
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Glucagon-like peptide-1 receptor is involved in learning and neuroprotection.
Matthew J During, Lei Cao, David S Zuzga, Jeremy S Francis, Helen L Fitzsimons, Xiangyang Jiao, Ross J Bland, Matthias Klugmann, William A Banks, Daniel J Drucker,[...]. Nat Med 2003
Matthew J During, Lei Cao, David S Zuzga, Jeremy S Francis, Helen L Fitzsimons, Xiangyang Jiao, Ross J Bland, Matthias Klugmann, William A Banks, Daniel J Drucker,[...]. Nat Med 2003
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Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy.
TracyAnn Perry, Harold W Holloway, Ananda Weerasuriya, Peter R Mouton, Kara Duffy, Julie A Mattison, Nigel H Greig. Exp Neurol 2007
TracyAnn Perry, Harold W Holloway, Ananda Weerasuriya, Peter R Mouton, Kara Duffy, Julie A Mattison, Nigel H Greig. Exp Neurol 2007
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Novel GLP-1R/GIPR co-agonist "twincretin" is neuroprotective in cell and rodent models of mild traumatic brain injury.
Ian A Tamargo, Miaad Bader, Yazhou Li, Seong-Jin Yu, Yun Wang, Konrad Talbot, Richard D DiMarchi, Chaim G Pick, Nigel H Greig. Exp Neurol 2017
Ian A Tamargo, Miaad Bader, Yazhou Li, Seong-Jin Yu, Yun Wang, Konrad Talbot, Richard D DiMarchi, Chaim G Pick, Nigel H Greig. Exp Neurol 2017
20
Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice.
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Lital Rachmany, David Tweedie, Yazhou Li, Vardit Rubovitch, Harold W Holloway, Jonathan Miller, Barry J Hoffer, Nigel H Greig, Chaim G Pick. Age (Dordr) 2013
20
A New Treatment Strategy for Parkinson's Disease through the Gut-Brain Axis: The Glucagon-Like Peptide-1 Receptor Pathway.
Dong Seok Kim, Ho-Il Choi, Yun Wang, Yu Luo, Barry J Hoffer, Nigel H Greig. Cell Transplant 2017
Dong Seok Kim, Ho-Il Choi, Yun Wang, Yu Luo, Barry J Hoffer, Nigel H Greig. Cell Transplant 2017
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Both classic Gs-cAMP/PKA/CREB and alternative Gs-cAMP/PKA/p38β/CREB signal pathways mediate exenatide-stimulated expression of M2 microglial markers.
Hai-Yun Wu, Xue-Qi Tang, Hao Liu, Xiao-Fang Mao, Yong-Xiang Wang. J Neuroimmunol 2018
Hai-Yun Wu, Xue-Qi Tang, Hao Liu, Xiao-Fang Mao, Yong-Xiang Wang. J Neuroimmunol 2018
20
Motor and cognitive advantages persist 12 months after exenatide exposure in Parkinson's disease.
Iciar Aviles-Olmos, John Dickson, Zinovia Kefalopoulou, Atbin Djamshidian, Joshua Kahan, Peter Ell, Peter Whitton, Richard Wyse, Tom Isaacs, Andrew Lees,[...]. J Parkinsons Dis 2014
Iciar Aviles-Olmos, John Dickson, Zinovia Kefalopoulou, Atbin Djamshidian, Joshua Kahan, Peter Ell, Peter Whitton, Richard Wyse, Tom Isaacs, Andrew Lees,[...]. J Parkinsons Dis 2014
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GLP-1 secretion by microglial cells and decreased CNS expression in obesity.
Camilla Kappe, Linda M Tracy, Cesare Patrone, Kerstin Iverfeldt, Åke Sjöholm. J Neuroinflammation 2012
Camilla Kappe, Linda M Tracy, Cesare Patrone, Kerstin Iverfeldt, Åke Sjöholm. J Neuroinflammation 2012
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The glucagon-like peptide 1 receptor agonist exendin-4 improves reference memory performance and decreases immobility in the forced swim test.
Ruben Isacson, Elisabet Nielsen, Karin Dannaeus, Göran Bertilsson, Cesare Patrone, Olof Zachrisson, Lilian Wikström. Eur J Pharmacol 2011
Ruben Isacson, Elisabet Nielsen, Karin Dannaeus, Göran Bertilsson, Cesare Patrone, Olof Zachrisson, Lilian Wikström. Eur J Pharmacol 2011
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Liraglutide is neurotrophic and neuroprotective in neuronal cultures and mitigates mild traumatic brain injury in mice.
Yazhou Li, Miaad Bader, Ian Tamargo, Vardit Rubovitch, David Tweedie, Chaim G Pick, Nigel H Greig. J Neurochem 2015
Yazhou Li, Miaad Bader, Ian Tamargo, Vardit Rubovitch, David Tweedie, Chaim G Pick, Nigel H Greig. J Neurochem 2015
20
Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system.
Alison Hamilton, Christian Hölscher. Neuroreport 2009
Alison Hamilton, Christian Hölscher. Neuroreport 2009
20
Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4.
TracyAnn Perry, Norman J Haughey, Mark P Mattson, Josephine M Egan, Nigel H Greig. J Pharmacol Exp Ther 2002
TracyAnn Perry, Norman J Haughey, Mark P Mattson, Josephine M Egan, Nigel H Greig. J Pharmacol Exp Ther 2002
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Glucagon-like peptide-1 inhibits LPS-induced IL-1beta production in cultured rat astrocytes.
Takashi Iwai, Satoshi Ito, Kahori Tanimitsu, Shunichi Udagawa, Jun-Ichiro Oka. Neurosci Res 2006
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Protective effects of the GLP-1 mimetic exendin-4 in Parkinson's disease.
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Dilan Athauda, Thomas Foltynie. Neuropharmacology 2018
20
Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4.
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Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells.
Yazhou Li, David Tweedie, Mark P Mattson, Harold W Holloway, Nigel H Greig. J Neurochem 2010
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20
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease.
Seung Pil Yun, Tae-In Kam, Nikhil Panicker, SangMin Kim, Yumin Oh, Jong-Sung Park, Seung-Hwan Kwon, Yong Joo Park, Senthilkumar S Karuppagounder, Hyejin Park,[...]. Nat Med 2018
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20
Exendin-4, a glucagon-like peptide-1 receptor agonist, provides neuroprotection in mice transient focal cerebral ischemia.
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20
Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis.
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20
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Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease.
Paula L McClean, Christian Hölscher. Neuropharmacology 2014
Paula L McClean, Christian Hölscher. Neuropharmacology 2014
20
Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease.
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Paula L McClean, Christian Hölscher. Neuropharmacology 2014
20
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers.
Theresa R Bomfim, Leticia Forny-Germano, Luciana B Sathler, Jordano Brito-Moreira, Jean-Christophe Houzel, Helena Decker, Michael A Silverman, Hala Kazi, Helen M Melo, Paula L McClean,[...]. J Clin Invest 2012
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Effect of D-Ala2GIP, a stable GIP receptor agonist on MPTP-induced neuronal impairments in mice.
Mahip K Verma, Rajan Goel, Krishnadas Nandakumar, Kumar V S Nemmani. Eur J Pharmacol 2017
Mahip K Verma, Rajan Goel, Krishnadas Nandakumar, Kumar V S Nemmani. Eur J Pharmacol 2017
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Role of the glucose-dependent insulinotropic polypeptide and its receptor in the central nervous system: therapeutic potential in neurological diseases.
Cláudia P Figueiredo, Fabrício A Pamplona, Tânia L Mazzuco, Aderbal S Aguiar, Roger Walz, Rui Daniel Schröder Prediger. Behav Pharmacol 2010
Cláudia P Figueiredo, Fabrício A Pamplona, Tânia L Mazzuco, Aderbal S Aguiar, Roger Walz, Rui Daniel Schröder Prediger. Behav Pharmacol 2010
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A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model.
Lijuan Shi, Zhihua Zhang, Lin Li, Christian Hölscher. Behav Brain Res 2017
Lijuan Shi, Zhihua Zhang, Lin Li, Christian Hölscher. Behav Brain Res 2017
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TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.
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Mychael V Lourenco, Julia R Clarke, Rudimar L Frozza, Theresa R Bomfim, Letícia Forny-Germano, André F Batista, Luciana B Sathler, Jordano Brito-Moreira, Olavo B Amaral, Cesar A Silva,[...]. Cell Metab 2013
20
Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling.
Aileen M Moloney, Rebecca J Griffin, Suzanne Timmons, Rosemary O'Connor, Rivka Ravid, Cora O'Neill. Neurobiol Aging 2010
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The incretin analogue D-Ala2GIP reduces plaque load, astrogliosis and oxidative stress in an APP/PS1 mouse model of Alzheimer's disease.
A M Duffy, C Hölscher. Neuroscience 2013
A M Duffy, C Hölscher. Neuroscience 2013
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Neuroprotective effects of glucose-dependent insulinotropic polypeptide in Alzheimer's disease.
Chenhui Ji, Guo-Fang Xue, Guanglai Li, Dongfang Li, Christian Hölscher. Rev Neurosci 2016
Chenhui Ji, Guo-Fang Xue, Guanglai Li, Dongfang Li, Christian Hölscher. Rev Neurosci 2016
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Neuroprotective effects of D-Ala(2)GIP on Alzheimer's disease biomarkers in an APP/PS1 mouse model.
Emilie Faivre, Christian Hölscher. Alzheimers Res Ther 2013
Emilie Faivre, Christian Hölscher. Alzheimers Res Ther 2013
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.