Patricia L Brubaker. Compr Physiol 2018
Times Cited: 55
Times Cited: 55
Times Cited
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Induction of intestinal epithelial proliferation by glucagon-like peptide 2.
D J Drucker, P Erlich, S L Asa, P L Brubaker. Proc Natl Acad Sci U S A 1996
D J Drucker, P Erlich, S L Asa, P L Brubaker. Proc Natl Acad Sci U S A 1996
32
The intestinal epithelial insulin-like growth factor-1 receptor links glucagon-like peptide-2 action to gut barrier function.
Charlotte X Dong, Wen Zhao, Chloe Solomon, Katherine J Rowland, Cameron Ackerley, Sylvie Robine, Martin Holzenberger, Tanja Gonska, Patricia L Brubaker. Endocrinology 2014
Charlotte X Dong, Wen Zhao, Chloe Solomon, Katherine J Rowland, Cameron Ackerley, Sylvie Robine, Martin Holzenberger, Tanja Gonska, Patricia L Brubaker. Endocrinology 2014
23
Physiology and pharmacology of the enteroendocrine hormone glucagon-like peptide-2.
Daniel J Drucker, Bernardo Yusta. Annu Rev Physiol 2014
Daniel J Drucker, Bernardo Yusta. Annu Rev Physiol 2014
18
Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability.
P D Cani, S Possemiers, T Van de Wiele, Y Guiot, A Everard, O Rottier, L Geurts, D Naslain, A Neyrinck, D M Lambert,[...]. Gut 2009
P D Cani, S Possemiers, T Van de Wiele, Y Guiot, A Everard, O Rottier, L Geurts, D Naslain, A Neyrinck, D M Lambert,[...]. Gut 2009
18
The essential role of insulin-like growth factor-1 in the intestinal tropic effects of glucagon-like peptide-2 in mice.
Philip E Dubé, Catherine L Forse, Jasmine Bahrami, Patricia L Brubaker. Gastroenterology 2006
Philip E Dubé, Catherine L Forse, Jasmine Bahrami, Patricia L Brubaker. Gastroenterology 2006
16
Enteroendocrine localization of GLP-2 receptor expression in humans and rodents.
B Yusta, L Huang, D Munroe, G Wolff, R Fantaske, S Sharma, L Demchyshyn, S L Asa, D J Drucker. Gastroenterology 2000
B Yusta, L Huang, D Munroe, G Wolff, R Fantaske, S Sharma, L Demchyshyn, S L Asa, D J Drucker. Gastroenterology 2000
16
Loss of glucagon-like peptide-2-induced proliferation following intestinal epithelial insulin-like growth factor-1-receptor deletion.
Katherine J Rowland, Shivangi Trivedi, Daiyoon Lee, Ken Wan, Rohit N Kulkarni, Martin Holzenberger, Patricia L Brubaker. Gastroenterology 2011
Katherine J Rowland, Shivangi Trivedi, Daiyoon Lee, Ken Wan, Rohit N Kulkarni, Martin Holzenberger, Patricia L Brubaker. Gastroenterology 2011
16
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
K J Livak, T D Schmittgen. Methods 2001
K J Livak, T D Schmittgen. Methods 2001
14
Regulation of the biological activity of glucagon-like peptide 2 in vivo by dipeptidyl peptidase IV.
D J Drucker, Q Shi, A Crivici, M Sumner-Smith, W Tavares, M Hill, L DeForest, S Cooper, P L Brubaker. Nat Biotechnol 1997
D J Drucker, Q Shi, A Crivici, M Sumner-Smith, W Tavares, M Hill, L DeForest, S Cooper, P L Brubaker. Nat Biotechnol 1997
14
Modulation of specific intestinal epithelial progenitors by enteric neurons.
M Bjerknes, H Cheng. Proc Natl Acad Sci U S A 2001
M Bjerknes, H Cheng. Proc Natl Acad Sci U S A 2001
14
Discovery, characterization, and clinical development of the glucagon-like peptides.
Daniel J Drucker, Joel F Habener, Jens Juul Holst. J Clin Invest 2017
Daniel J Drucker, Joel F Habener, Jens Juul Holst. J Clin Invest 2017
14
GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody.
Charles Pyke, R Scott Heller, Rikke K Kirk, Cathrine Ørskov, Steffen Reedtz-Runge, Peter Kaastrup, Anders Hvelplund, Linda Bardram, Dan Calatayud, Lotte Bjerre Knudsen. Endocrinology 2014
Charles Pyke, R Scott Heller, Rikke K Kirk, Cathrine Ørskov, Steffen Reedtz-Runge, Peter Kaastrup, Anders Hvelplund, Linda Bardram, Dan Calatayud, Lotte Bjerre Knudsen. Endocrinology 2014
14
GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors.
Cathrine Ørskov, Bolette Hartmann, Steen Seier Poulsen, Jesper Thulesen, Kristine Juul Hare, Jens Juul Holst. Regul Pept 2005
Cathrine Ørskov, Bolette Hartmann, Steen Seier Poulsen, Jesper Thulesen, Kristine Juul Hare, Jens Juul Holst. Regul Pept 2005
14
Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2.
D G Munroe, A K Gupta, F Kooshesh, T B Vyas, G Rizkalla, H Wang, L Demchyshyn, Z J Yang, R K Kamboj, H Chen,[...]. Proc Natl Acad Sci U S A 1999
D G Munroe, A K Gupta, F Kooshesh, T B Vyas, G Rizkalla, H Wang, L Demchyshyn, Z J Yang, R K Kamboj, H Chen,[...]. Proc Natl Acad Sci U S A 1999
14
Glucagon-like peptide 1 (GLP-1).
T D Müller, B Finan, S R Bloom, D D'Alessio, D J Drucker, P R Flatt, A Fritsche, F Gribble, H J Grill, J F Habener,[...]. Mol Metab 2019
T D Müller, B Finan, S R Bloom, D D'Alessio, D J Drucker, P R Flatt, A Fritsche, F Gribble, H J Grill, J F Habener,[...]. Mol Metab 2019
14
Glucagon-like peptide-2 enhances intestinal epithelial barrier function of both transcellular and paracellular pathways in the mouse.
M A Benjamin, D M McKay, P C Yang, H Cameron, M H Perdue. Gut 2000
M A Benjamin, D M McKay, P C Yang, H Cameron, M H Perdue. Gut 2000
12
GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow.
Xinfu Guan, Heidi E Karpen, John Stephens, John T Bukowski, Sanyong Niu, Guangcheng Zhang, Barbara Stoll, Milton J Finegold, Jens J Holst, Darryl Hadsell,[...]. Gastroenterology 2006
Xinfu Guan, Heidi E Karpen, John Stephens, John T Bukowski, Sanyong Niu, Guangcheng Zhang, Barbara Stoll, Milton J Finegold, Jens J Holst, Darryl Hadsell,[...]. Gastroenterology 2006
12
GLP-1R Agonists Modulate Enteric Immune Responses Through the Intestinal Intraepithelial Lymphocyte GLP-1R.
Bernardo Yusta, Laurie L Baggio, Jacqueline Koehler, Dianne Holland, Xiemin Cao, Lee J Pinnell, Kathene C Johnson-Henry, William Yeung, Michael G Surette, K W Annie Bang,[...]. Diabetes 2015
Bernardo Yusta, Laurie L Baggio, Jacqueline Koehler, Dianne Holland, Xiemin Cao, Lee J Pinnell, Kathene C Johnson-Henry, William Yeung, Michael G Surette, K W Annie Bang,[...]. Diabetes 2015
12
Identification and characterization of GLP-1 receptor-expressing cells using a new transgenic mouse model.
Paul Richards, Helen E Parker, Alice E Adriaenssens, Joshua M Hodgson, Simon C Cork, Stefan Trapp, Fiona M Gribble, Frank Reimann. Diabetes 2014
Paul Richards, Helen E Parker, Alice E Adriaenssens, Joshua M Hodgson, Simon C Cork, Stefan Trapp, Fiona M Gribble, Frank Reimann. Diabetes 2014
12
Intestinal function in mice with small bowel growth induced by glucagon-like peptide-2.
P L Brubaker, A Izzo, M Hill, D J Drucker. Am J Physiol 1997
P L Brubaker, A Izzo, M Hill, D J Drucker. Am J Physiol 1997
12
Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohn's disease.
Alan L Buchman, Seymour Katz, John C Fang, Charles N Bernstein, Souheil G Abou-Assi. Inflamm Bowel Dis 2010
Alan L Buchman, Seymour Katz, John C Fang, Charles N Bernstein, Souheil G Abou-Assi. Inflamm Bowel Dis 2010
12
Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man.
R Eissele, R Göke, S Willemer, H P Harthus, H Vermeer, R Arnold, B Göke. Eur J Clin Invest 1992
R Eissele, R Göke, S Willemer, H P Harthus, H Vermeer, R Arnold, B Göke. Eur J Clin Invest 1992
12
Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome.
P B Jeppesen, R Gilroy, M Pertkiewicz, J P Allard, B Messing, S J O'Keefe. Gut 2011
P B Jeppesen, R Gilroy, M Pertkiewicz, J P Allard, B Messing, S J O'Keefe. Gut 2011
12
Glucagon-like peptide-2 increases intestinal lipid absorption and chylomicron production via CD36.
Joanne Hsieh, Christine Longuet, Adriano Maida, Jasmine Bahrami, Elaine Xu, Christopher L Baker, Patricia L Brubaker, Daniel J Drucker, Khosrow Adeli. Gastroenterology 2009
Joanne Hsieh, Christine Longuet, Adriano Maida, Jasmine Bahrami, Elaine Xu, Christopher L Baker, Patricia L Brubaker, Daniel J Drucker, Khosrow Adeli. Gastroenterology 2009
10
Intestinal growth-promoting properties of glucagon-like peptide-2 in mice.
C H Tsai, M Hill, S L Asa, P L Brubaker, D J Drucker. Am J Physiol 1997
C H Tsai, M Hill, S L Asa, P L Brubaker, D J Drucker. Am J Physiol 1997
10
Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1.
Daniel J Drucker. Cell Metab 2018
Daniel J Drucker. Cell Metab 2018
10
Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas.
C Orskov, J J Holst, S Knuhtsen, F G Baldissera, S S Poulsen, O V Nielsen. Endocrinology 1986
C Orskov, J J Holst, S Knuhtsen, F G Baldissera, S S Poulsen, O V Nielsen. Endocrinology 1986
10
Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide.
Y Rouillé, S Martin, D F Steiner. J Biol Chem 1995
Y Rouillé, S Martin, D F Steiner. J Biol Chem 1995
10
Pharmacological Characterization of Apraglutide, a Novel Long-Acting Peptidic Glucagon-Like Peptide-2 Agonist, for the Treatment of Short Bowel Syndrome.
Diane M Hargrove, Sudarkodi Alagarsamy, Glenn Croston, Régent Laporte, Steve Qi, Karthik Srinivasan, Javier Sueiras-Diaz, Kazimierz Wiśniewski, Jennifer Hartwig, Mark Lu,[...]. J Pharmacol Exp Ther 2020
Diane M Hargrove, Sudarkodi Alagarsamy, Glenn Croston, Régent Laporte, Steve Qi, Karthik Srinivasan, Javier Sueiras-Diaz, Kazimierz Wiśniewski, Jennifer Hartwig, Mark Lu,[...]. J Pharmacol Exp Ther 2020
33
Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients.
P B Jeppesen, E L Sanguinetti, A Buchman, L Howard, J S Scolapio, T R Ziegler, J Gregory, K A Tappenden, J Holst, P B Mortensen. Gut 2005
P B Jeppesen, E L Sanguinetti, A Buchman, L Howard, J S Scolapio, T R Ziegler, J Gregory, K A Tappenden, J Holst, P B Mortensen. Gut 2005
10
Localization of Glucagon-Like Peptide-2 Receptor Expression in the Mouse.
Bernardo Yusta, Dianne Matthews, Jacqueline A Koehler, Gemma Pujadas, Kiran Deep Kaur, Daniel J Drucker. Endocrinology 2019
Bernardo Yusta, Dianne Matthews, Jacqueline A Koehler, Gemma Pujadas, Kiran Deep Kaur, Daniel J Drucker. Endocrinology 2019
23
Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.
Gwen Tolhurst, Helen Heffron, Yu Shan Lam, Helen E Parker, Abdella M Habib, Eleftheria Diakogiannaki, Jennifer Cameron, Johannes Grosse, Frank Reimann, Fiona M Gribble. Diabetes 2012
Gwen Tolhurst, Helen Heffron, Yu Shan Lam, Helen E Parker, Abdella M Habib, Eleftheria Diakogiannaki, Jennifer Cameron, Johannes Grosse, Frank Reimann, Fiona M Gribble. Diabetes 2012
10
Pharmacology, physiology, and mechanisms of incretin hormone action.
Jonathan E Campbell, Daniel J Drucker. Cell Metab 2013
Jonathan E Campbell, Daniel J Drucker. Cell Metab 2013
9
Glucagon-like peptide 2 is a potent growth factor for small intestine and colon.
D A Litvak, M R Hellmich, B M Evers, N A Banker, C M Townsend. J Gastrointest Surg 1998
D A Litvak, M R Hellmich, B M Evers, N A Banker, C M Townsend. J Gastrointest Surg 1998
9
GLP-1 Receptor Expression Within the Human Heart.
Laurie L Baggio, Bernardo Yusta, Erin E Mulvihill, Xiemin Cao, Catherine J Streutker, Jagdish Butany, Thomas P Cappola, Kenneth B Margulies, Daniel J Drucker. Endocrinology 2018
Laurie L Baggio, Bernardo Yusta, Erin E Mulvihill, Xiemin Cao, Catherine J Streutker, Jagdish Butany, Thomas P Cappola, Kenneth B Margulies, Daniel J Drucker. Endocrinology 2018
9
Upregulation of SGLT-1 transport activity in rat jejunum induced by GLP-2 infusion in vivo.
C I Cheeseman. Am J Physiol 1997
C I Cheeseman. Am J Physiol 1997
9
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.
Akira Hirasawa, Keiko Tsumaya, Takeo Awaji, Susumu Katsuma, Tetsuya Adachi, Masateru Yamada, Yukihiko Sugimoto, Shunichi Miyazaki, Gozoh Tsujimoto. Nat Med 2005
Akira Hirasawa, Keiko Tsumaya, Takeo Awaji, Susumu Katsuma, Tetsuya Adachi, Masateru Yamada, Yukihiko Sugimoto, Shunichi Miyazaki, Gozoh Tsujimoto. Nat Med 2005
9
Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion.
A S Rocca, P L Brubaker. Endocrinology 1999
A S Rocca, P L Brubaker. Endocrinology 1999
9
Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem.
P J Larsen, M Tang-Christensen, J J Holst, C Orskov. Neuroscience 1997
P J Larsen, M Tang-Christensen, J J Holst, C Orskov. Neuroscience 1997
9
Glucose sensing in L cells: a primary cell study.
Frank Reimann, Abdella M Habib, Gwen Tolhurst, Helen E Parker, Gareth J Rogers, Fiona M Gribble. Cell Metab 2008
Frank Reimann, Abdella M Habib, Gwen Tolhurst, Helen E Parker, Gareth J Rogers, Fiona M Gribble. Cell Metab 2008
9
Exon duplication and divergence in the human preproglucagon gene.
G I Bell, R Sanchez-Pescador, P J Laybourn, R C Najarian. Nature 1983
G I Bell, R Sanchez-Pescador, P J Laybourn, R C Najarian. Nature 1983
9
Protein kinase Czeta is required for oleic acid-induced secretion of glucagon-like peptide-1 by intestinal endocrine L cells.
Roman Iakoubov, Angelo Izzo, Andrea Yeung, Catharine I Whiteside, Patricia L Brubaker. Endocrinology 2007
Roman Iakoubov, Angelo Izzo, Andrea Yeung, Catharine I Whiteside, Patricia L Brubaker. Endocrinology 2007
9
GLP-1R agonists promote normal and neoplastic intestinal growth through mechanisms requiring Fgf7.
Jacqueline A Koehler, Laurie L Baggio, Bernardo Yusta, Christine Longuet, Katherine J Rowland, Xiemin Cao, Dianne Holland, Patricia L Brubaker, Daniel J Drucker. Cell Metab 2015
Jacqueline A Koehler, Laurie L Baggio, Bernardo Yusta, Christine Longuet, Katherine J Rowland, Xiemin Cao, Dianne Holland, Patricia L Brubaker, Daniel J Drucker. Cell Metab 2015
9
Mucosal adaptation to enteral nutrients is dependent on the physiologic actions of glucagon-like peptide-2 in mice.
Eric D Shin, Jennifer L Estall, Angelo Izzo, Daniel J Drucker, Patricia L Brubaker. Gastroenterology 2005
Eric D Shin, Jennifer L Estall, Angelo Izzo, Daniel J Drucker, Patricia L Brubaker. Gastroenterology 2005
9
Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.
Yongjia Feng, Farok R Demehri, Weidong Xiao, Yu-Hwai Tsai, Jennifer C Jones, Constance D Brindley, David W Threadgill, Jens J Holst, Bolette Hartmann, Terrence A Barrett,[...]. Cell Mol Gastroenterol Hepatol 2017
Yongjia Feng, Farok R Demehri, Weidong Xiao, Yu-Hwai Tsai, Jennifer C Jones, Constance D Brindley, David W Threadgill, Jens J Holst, Bolette Hartmann, Terrence A Barrett,[...]. Cell Mol Gastroenterol Hepatol 2017
19
Emerging treatments for short bowel syndrome in adult patients.
Lore Billiauws, Francisca Joly. Expert Rev Gastroenterol Hepatol 2019
Lore Billiauws, Francisca Joly. Expert Rev Gastroenterol Hepatol 2019
29
Circadian GLP-1 Secretion in Mice Is Dependent on the Intestinal Microbiome for Maintenance of Diurnal Metabolic Homeostasis.
Sarah E Martchenko, Alexandre Martchenko, Brian J Cox, Kendra Naismith, Alison Waller, Patrick Gurges, Maegan E Sweeney, Dana J Philpott, Patricia L Brubaker. Diabetes 2020
Sarah E Martchenko, Alexandre Martchenko, Brian J Cox, Kendra Naismith, Alison Waller, Patrick Gurges, Maegan E Sweeney, Dana J Philpott, Patricia L Brubaker. Diabetes 2020
20
Glucagon-like peptide-2 increases dysplasia in rodent models of colon cancer.
Shivangi Trivedi, Stuart C Wiber, Hala M El-Zimaity, Patricia L Brubaker. Am J Physiol Gastrointest Liver Physiol 2012
Shivangi Trivedi, Stuart C Wiber, Hala M El-Zimaity, Patricia L Brubaker. Am J Physiol Gastrointest Liver Physiol 2012
10
Outcomes from a 12-Week, Open-Label, Multicenter Clinical Trial of Teduglutide in Pediatric Short Bowel Syndrome.
Beth A Carter, Valeria C Cohran, Conrad R Cole, Mark R Corkins, Reed A Dimmitt, Christopher Duggan, Susan Hill, Simon Horslen, Joel D Lim, David F Mercer,[...]. J Pediatr 2017
Beth A Carter, Valeria C Cohran, Conrad R Cole, Mark R Corkins, Reed A Dimmitt, Christopher Duggan, Susan Hill, Simon Horslen, Joel D Lim, David F Mercer,[...]. J Pediatr 2017
7
Sustained glucagon-like peptide-2 infusion is required for intestinal adaptation, and cessation reverses increased cellularity in rats with intestinal failure.
Matthew C Koopmann, Xueyan Chen, Jens J Holst, Denise M Ney. Am J Physiol Gastrointest Liver Physiol 2010
Matthew C Koopmann, Xueyan Chen, Jens J Holst, Denise M Ney. Am J Physiol Gastrointest Liver Physiol 2010
19
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.