Yasar Arfat T Kasu, Samrawit Alemu, Angela Lamari, Nicole Loew, Christopher S Brower. Mol Cell Biol 2018
Times Cited: 11
Times Cited: 11
Times Cited
Times Co-cited
Similarity
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
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Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
Christopher S Brower, Konstantin I Piatkov, Alexander Varshavsky. Mol Cell 2013
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Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo.
Sílvia Porta, Yan Xu, Clark R Restrepo, Linda K Kwong, Bin Zhang, Hannah J Brown, Edward B Lee, John Q Trojanowski, Virginia M-Y Lee. Nat Commun 2018
Sílvia Porta, Yan Xu, Clark R Restrepo, Linda K Kwong, Bin Zhang, Hannah J Brown, Edward B Lee, John Q Trojanowski, Virginia M-Y Lee. Nat Commun 2018
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Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity.
Yong-Jie Zhang, Ya-Fei Xu, Casey Cook, Tania F Gendron, Paul Roettges, Christopher D Link, Wen-Lang Lin, Jimei Tong, Monica Castanedes-Casey, Peter Ash,[...]. Proc Natl Acad Sci U S A 2009
Yong-Jie Zhang, Ya-Fei Xu, Casey Cook, Tania F Gendron, Paul Roettges, Christopher D Link, Wen-Lang Lin, Jimei Tong, Monica Castanedes-Casey, Peter Ash,[...]. Proc Natl Acad Sci U S A 2009
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An acetylation switch controls TDP-43 function and aggregation propensity.
Todd J Cohen, Andrew W Hwang, Clark R Restrepo, Chao-Xing Yuan, John Q Trojanowski, Virginia M Y Lee. Nat Commun 2015
Todd J Cohen, Andrew W Hwang, Clark R Restrepo, Chao-Xing Yuan, John Q Trojanowski, Virginia M Y Lee. Nat Commun 2015
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TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates.
Florent Laferrière, Zuzanna Maniecka, Manuela Pérez-Berlanga, Marian Hruska-Plochan, Larissa Gilhespy, Eva-Maria Hock, Ulrich Wagner, Tariq Afroz, Paul J Boersema, Gery Barmettler,[...]. Nat Neurosci 2019
Florent Laferrière, Zuzanna Maniecka, Manuela Pérez-Berlanga, Marian Hruska-Plochan, Larissa Gilhespy, Eva-Maria Hock, Ulrich Wagner, Tariq Afroz, Paul J Boersema, Gery Barmettler,[...]. Nat Neurosci 2019
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Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation.
Matthew J Winton, Lionel M Igaz, Margaret M Wong, Linda K Kwong, John Q Trojanowski, Virginia M-Y Lee. J Biol Chem 2008
Matthew J Winton, Lionel M Igaz, Margaret M Wong, Linda K Kwong, John Q Trojanowski, Virginia M-Y Lee. J Biol Chem 2008
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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama, Kenji Ikeda, Takashi Nonaka, Hiroshi Mori, David Mann, Kuniaki Tsuchiya, Mari Yoshida, Yoshio Hashizume,[...]. Biochem Biophys Res Commun 2006
Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama, Kenji Ikeda, Takashi Nonaka, Hiroshi Mori, David Mann, Kuniaki Tsuchiya, Mari Yoshida, Yoshio Hashizume,[...]. Biochem Biophys Res Commun 2006
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Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils.
Shotaro Shimonaka, Takashi Nonaka, Genjiro Suzuki, Shin-Ichi Hisanaga, Masato Hasegawa. J Biol Chem 2016
Shotaro Shimonaka, Takashi Nonaka, Genjiro Suzuki, Shin-Ichi Hisanaga, Masato Hasegawa. J Biol Chem 2016
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Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43.
Takashi Nonaka, Fuyuki Kametani, Tetsuaki Arai, Haruhiko Akiyama, Masato Hasegawa. Hum Mol Genet 2009
Takashi Nonaka, Fuyuki Kametani, Tetsuaki Arai, Haruhiko Akiyama, Masato Hasegawa. Hum Mol Genet 2009
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An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice.
Adam K Walker, Kalyan Tripathy, Clark R Restrepo, Guanghui Ge, Yan Xu, Linda K Kwong, John Q Trojanowski, Virginia M-Y Lee. Hum Mol Genet 2015
Adam K Walker, Kalyan Tripathy, Clark R Restrepo, Guanghui Ge, Yan Xu, Linda K Kwong, John Q Trojanowski, Virginia M-Y Lee. Hum Mol Genet 2015
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Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice.
Lionel M Igaz, Linda K Kwong, Edward B Lee, Alice Chen-Plotkin, Eric Swanson, Travis Unger, Joe Malunda, Yan Xu, Matthew J Winton, John Q Trojanowski,[...]. J Clin Invest 2011
Lionel M Igaz, Linda K Kwong, Edward B Lee, Alice Chen-Plotkin, Eric Swanson, Travis Unger, Joe Malunda, Yan Xu, Matthew J Winton, John Q Trojanowski,[...]. J Clin Invest 2011
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Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies.
Lionel M Igaz, Linda K Kwong, Alice Chen-Plotkin, Matthew J Winton, Travis L Unger, Yan Xu, Manuela Neumann, John Q Trojanowski, Virginia M-Y Lee. J Biol Chem 2009
Lionel M Igaz, Linda K Kwong, Alice Chen-Plotkin, Matthew J Winton, Travis L Unger, Yan Xu, Manuela Neumann, John Q Trojanowski, Virginia M-Y Lee. J Biol Chem 2009
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Prion-like properties of pathological TDP-43 aggregates from diseased brains.
Takashi Nonaka, Masami Masuda-Suzukake, Tetsuaki Arai, Yoko Hasegawa, Hiroyasu Akatsu, Tomokazu Obi, Mari Yoshida, Shigeo Murayama, David M A Mann, Haruhiko Akiyama,[...]. Cell Rep 2013
Takashi Nonaka, Masami Masuda-Suzukake, Tetsuaki Arai, Yoko Hasegawa, Hiroyasu Akatsu, Tomokazu Obi, Mari Yoshida, Shigeo Murayama, David M A Mann, Haruhiko Akiyama,[...]. Cell Rep 2013
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An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes.
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
Shun-Jia Chen, Xia Wu, Brandon Wadas, Jang-Hyun Oh, Alexander Varshavsky. Science 2017
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N-terminal acetylation of cellular proteins creates specific degradation signals.
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
Cheol-Sang Hwang, Anna Shemorry, Alexander Varshavsky. Science 2010
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The N-end rule pathway.
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
Takafumi Tasaki, Shashikanth M Sriram, Kyong Soo Park, Yong Tae Kwon. Annu Rev Biochem 2012
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The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD.
Britt A Berning, Adam K Walker. Front Neurosci 2019
Britt A Berning, Adam K Walker. Front Neurosci 2019
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N-degron and C-degron pathways of protein degradation.
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
Alexander Varshavsky. Proc Natl Acad Sci U S A 2019
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Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species.
Emma L Scotter, Caroline Vance, Agnes L Nishimura, Youn-Bok Lee, Han-Jou Chen, Hazel Urwin, Valentina Sardone, Jacqueline C Mitchell, Boris Rogelj, David C Rubinsztein,[...]. J Cell Sci 2014
Emma L Scotter, Caroline Vance, Agnes L Nishimura, Youn-Bok Lee, Han-Jou Chen, Hazel Urwin, Valentina Sardone, Jacqueline C Mitchell, Boris Rogelj, David C Rubinsztein,[...]. J Cell Sci 2014
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Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Masato Hasegawa, Tetsuaki Arai, Takashi Nonaka, Fuyuki Kametani, Mari Yoshida, Yoshio Hashizume, Thomas G Beach, Emanuele Buratti, Francisco Baralle, Mitsuya Morita,[...]. Ann Neurol 2008
Masato Hasegawa, Tetsuaki Arai, Takashi Nonaka, Fuyuki Kametani, Mari Yoshida, Yoshio Hashizume, Thomas G Beach, Emanuele Buratti, Francisco Baralle, Mitsuya Morita,[...]. Ann Neurol 2008
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Molecular analysis and biochemical classification of TDP-43 proteinopathy.
Hiroshi Tsuji, Tetsuaki Arai, Fuyuki Kametani, Takashi Nonaka, Makiko Yamashita, Masami Suzukake, Masato Hosokawa, Mari Yoshida, Hiroyuki Hatsuta, Masaki Takao,[...]. Brain 2012
Hiroshi Tsuji, Tetsuaki Arai, Fuyuki Kametani, Takashi Nonaka, Makiko Yamashita, Masami Suzukake, Masato Hosokawa, Mari Yoshida, Hiroyuki Hatsuta, Masaki Takao,[...]. Brain 2012
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TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Ian R Mackenzie, Alexandra M Nicholson, Mohona Sarkar, James Messing, Maria D Purice, Cyril Pottier, Kavya Annu, Matt Baker, Ralph B Perkerson, Aishe Kurti,[...]. Neuron 2017
Ian R Mackenzie, Alexandra M Nicholson, Mohona Sarkar, James Messing, Maria D Purice, Cyril Pottier, Kavya Annu, Matt Baker, Ralph B Perkerson, Aishe Kurti,[...]. Neuron 2017
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Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.
Yong-Jie Zhang, Ya-fei Xu, Chad A Dickey, Emanuele Buratti, Francisco Baralle, Rachel Bailey, Stuart Pickering-Brown, Dennis Dickson, Leonard Petrucelli. J Neurosci 2007
Yong-Jie Zhang, Ya-fei Xu, Chad A Dickey, Emanuele Buratti, Francisco Baralle, Rachel Bailey, Stuart Pickering-Brown, Dennis Dickson, Leonard Petrucelli. J Neurosci 2007
27
A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.
Ailin Wang, Alexander E Conicella, Hermann Broder Schmidt, Erik W Martin, Shannon N Rhoads, Ashley N Reeb, Amanda Nourse, Daniel Ramirez Montero, Veronica H Ryan, Rajat Rohatgi,[...]. EMBO J 2018
Ailin Wang, Alexander E Conicella, Hermann Broder Schmidt, Erik W Martin, Shannon N Rhoads, Ashley N Reeb, Amanda Nourse, Daniel Ramirez Montero, Veronica H Ryan, Rajat Rohatgi,[...]. EMBO J 2018
27
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
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Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis.
Shuo-Chien Ling, Magdalini Polymenidou, Don W Cleveland. Neuron 2013
Shuo-Chien Ling, Magdalini Polymenidou, Don W Cleveland. Neuron 2013
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Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization.
Emile S Pinarbasi, Tolga Cağatay, Ho Yee Joyce Fung, Ying C Li, Yuh Min Chook, Philip J Thomas. Sci Rep 2018
Emile S Pinarbasi, Tolga Cağatay, Ho Yee Joyce Fung, Ying C Li, Yuh Min Chook, Philip J Thomas. Sci Rep 2018
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Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
Ian R A Mackenzie, Eileen H Bigio, Paul G Ince, Felix Geser, Manuela Neumann, Nigel J Cairns, Linda K Kwong, Mark S Forman, John Ravits, Heather Stewart,[...]. Ann Neurol 2007
Ian R A Mackenzie, Eileen H Bigio, Paul G Ince, Felix Geser, Manuela Neumann, Nigel J Cairns, Linda K Kwong, Mark S Forman, John Ravits, Heather Stewart,[...]. Ann Neurol 2007
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A role for calpain-dependent cleavage of TDP-43 in amyotrophic lateral sclerosis pathology.
Takenari Yamashita, Takuto Hideyama, Kosuke Hachiga, Sayaka Teramoto, Jiro Takano, Nobuhisa Iwata, Takaomi C Saido, Shin Kwak. Nat Commun 2012
Takenari Yamashita, Takuto Hideyama, Kosuke Hachiga, Sayaka Teramoto, Jiro Takano, Nobuhisa Iwata, Takaomi C Saido, Shin Kwak. Nat Commun 2012
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Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
Adam K Walker, Krista J Spiller, Guanghui Ge, Allen Zheng, Yan Xu, Melissa Zhou, Kalyan Tripathy, Linda K Kwong, John Q Trojanowski, Virginia M-Y Lee. Acta Neuropathol 2015
Adam K Walker, Krista J Spiller, Guanghui Ge, Allen Zheng, Yan Xu, Melissa Zhou, Kalyan Tripathy, Linda K Kwong, John Q Trojanowski, Virginia M-Y Lee. Acta Neuropathol 2015
27
Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene.
Pablo Arrisi Mercado, Youhna M Ayala, Maurizio Romano, Emanuele Buratti, Francisco E Baralle. Nucleic Acids Res 2005
Pablo Arrisi Mercado, Youhna M Ayala, Maurizio Romano, Emanuele Buratti, Francisco E Baralle. Nucleic Acids Res 2005
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Hyperphosphorylation as a defense mechanism to reduce TDP-43 aggregation.
Huei-Ying Li, Po-An Yeh, Hsiu-Chiang Chiu, Chiou-Yang Tang, Benjamin Pang-hsien Tu. PLoS One 2011
Huei-Ying Li, Po-An Yeh, Hsiu-Chiang Chiu, Chiou-Yang Tang, Benjamin Pang-hsien Tu. PLoS One 2011
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Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization.
Amandine Molliex, Jamshid Temirov, Jihun Lee, Maura Coughlin, Anderson P Kanagaraj, Hong Joo Kim, Tanja Mittag, J Paul Taylor. Cell 2015
Amandine Molliex, Jamshid Temirov, Jihun Lee, Maura Coughlin, Anderson P Kanagaraj, Hong Joo Kim, Tanja Mittag, J Paul Taylor. Cell 2015
27
Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases.
Hanae Nakashima-Yasuda, Kunihiro Uryu, John Robinson, Sharon X Xie, Howard Hurtig, John E Duda, Steven E Arnold, Andrew Siderowf, Murray Grossman, James B Leverenz,[...]. Acta Neuropathol 2007
Hanae Nakashima-Yasuda, Kunihiro Uryu, John Robinson, Sharon X Xie, Howard Hurtig, John E Duda, Steven E Arnold, Andrew Siderowf, Murray Grossman, James B Leverenz,[...]. Acta Neuropathol 2007
27
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
27
In vitro prion-like behaviour of TDP-43 in ALS.
Phillip Smethurst, Jia Newcombe, Claire Troakes, Roberto Simone, Yun-Ru Chen, Rickie Patani, Katie Sidle. Neurobiol Dis 2016
Phillip Smethurst, Jia Newcombe, Claire Troakes, Roberto Simone, Yun-Ru Chen, Rickie Patani, Katie Sidle. Neurobiol Dis 2016
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Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice.
Ya-Fei Xu, Tania F Gendron, Yong-Jie Zhang, Wen-Lang Lin, Simon D'Alton, Hong Sheng, Monica Castanedes Casey, Jimei Tong, Joshua Knight, Xin Yu,[...]. J Neurosci 2010
Ya-Fei Xu, Tania F Gendron, Yong-Jie Zhang, Wen-Lang Lin, Simon D'Alton, Hong Sheng, Monica Castanedes Casey, Jimei Tong, Joshua Knight, Xin Yu,[...]. J Neurosci 2010
27
Structural determinants of the cellular localization and shuttling of TDP-43.
Youhna M Ayala, Paola Zago, Andrea D'Ambrogio, Ya-Fei Xu, Leonard Petrucelli, Emanuele Buratti, Francisco E Baralle. J Cell Sci 2008
Youhna M Ayala, Paola Zago, Andrea D'Ambrogio, Ya-Fei Xu, Leonard Petrucelli, Emanuele Buratti, Francisco E Baralle. J Cell Sci 2008
27
Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease.
Claudia Schwab, Tetsuaki Arai, Masato Hasegawa, Sheng Yu, Patrick L McGeer. J Neuropathol Exp Neurol 2008
Claudia Schwab, Tetsuaki Arai, Masato Hasegawa, Sheng Yu, Patrick L McGeer. J Neuropathol Exp Neurol 2008
27
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.
Magdalini Polymenidou, Clotilde Lagier-Tourenne, Kasey R Hutt, Stephanie C Huelga, Jacqueline Moran, Tiffany Y Liang, Shuo-Chien Ling, Eveline Sun, Edward Wancewicz, Curt Mazur,[...]. Nat Neurosci 2011
Magdalini Polymenidou, Clotilde Lagier-Tourenne, Kasey R Hutt, Stephanie C Huelga, Jacqueline Moran, Tiffany Y Liang, Shuo-Chien Ling, Eveline Sun, Edward Wancewicz, Curt Mazur,[...]. Nat Neurosci 2011
27
Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43).
Eva Bentmann, Manuela Neumann, Sabina Tahirovic, Ramona Rodde, Dorothee Dormann, Christian Haass. J Biol Chem 2012
Eva Bentmann, Manuela Neumann, Sabina Tahirovic, Ramona Rodde, Dorothee Dormann, Christian Haass. J Biol Chem 2012
27
TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues.
Hao-Ru Li, Wan-Chin Chiang, Po-Chun Chou, Won-Jing Wang, Jie-Rong Huang. J Biol Chem 2018
Hao-Ru Li, Wan-Chin Chiang, Po-Chun Chou, Won-Jing Wang, Jie-Rong Huang. J Biol Chem 2018
27
TDP-43 post-translational modifications in health and disease.
Emanuele Buratti. Expert Opin Ther Targets 2018
Emanuele Buratti. Expert Opin Ther Targets 2018
27
The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity.
Quan Li, Moe Yokoshi, Hitomi Okada, Yukio Kawahara. Nat Commun 2015
Quan Li, Moe Yokoshi, Hitomi Okada, Yukio Kawahara. Nat Commun 2015
27
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing.
Emanuele Buratti, Antonia Brindisi, Maurizio Giombi, Sergio Tisminetzky, Youhna M Ayala, Francisco E Baralle. J Biol Chem 2005
Emanuele Buratti, Antonia Brindisi, Maurizio Giombi, Sergio Tisminetzky, Youhna M Ayala, Francisco E Baralle. J Biol Chem 2005
27
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease.
Emanuele Buratti, Francisco E Baralle. Front Biosci 2008
Emanuele Buratti, Francisco E Baralle. Front Biosci 2008
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Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration.
Edward B Lee, Virginia M-Y Lee, John Q Trojanowski. Nat Rev Neurosci 2011
Edward B Lee, Virginia M-Y Lee, John Q Trojanowski. Nat Rev Neurosci 2011
27
ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
Alexander E Conicella, Gül H Zerze, Jeetain Mittal, Nicolas L Fawzi. Structure 2016
Alexander E Conicella, Gül H Zerze, Jeetain Mittal, Nicolas L Fawzi. Structure 2016
27
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.