A citation-based method for searching scientific literature

Magnus Ingelman-Sundberg, Volker M Lauschke. Pharmacogenomics 2018
Times Cited: 10







List of co-cited articles
253 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.
Catherine C Bell, Delilah F G Hendriks, Sabrina M L Moro, Ewa Ellis, Joanne Walsh, Anna Renblom, Lisa Fredriksson Puigvert, Anita C A Dankers, Frank Jacobs, Jan Snoeys,[...]. Sci Rep 2016
359
70

Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates.
Volker M Lauschke, Delilah F G Hendriks, Catherine C Bell, Tommy B Andersson, Magnus Ingelman-Sundberg. Chem Res Toxicol 2016
148
60

Microscale culture of human liver cells for drug development.
Salman R Khetani, Sangeeta N Bhatia. Nat Biotechnol 2008
777
60

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation.
Volker M Lauschke, Sabine U Vorrink, Sabrina M L Moro, Fatemah Rezayee, Åsa Nordling, Delilah F G Hendriks, Catherine C Bell, Rowena Sison-Young, B Kevin Park, Christopher E Goldring,[...]. Hepatology 2016
71
60

Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics.
Sabine U Vorrink, Shahid Ullah, Staffan Schmidt, Jatin Nandania, Vidya Velagapudi, Olof Beck, Magnus Ingelman-Sundberg, Volker M Lauschke. FASEB J 2017
92
60

Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study.
Catherine C Bell, Anita C A Dankers, Volker M Lauschke, Rowena Sison-Young, Roz Jenkins, Cliff Rowe, Chris E Goldring, Kevin Park, Sophie L Regan, Tracy Walker,[...]. Toxicol Sci 2018
160
60

Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.
Catherine C Bell, Volker M Lauschke, Sabine U Vorrink, Henrik Palmgren, Rodger Duffin, Tommy B Andersson, Magnus Ingelman-Sundberg. Drug Metab Dispos 2017
98
60

Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery.
Lorna Ewart, Eva-Maria Dehne, Kristin Fabre, Susan Gibbs, James Hickman, Ellinor Hornberg, Magnus Ingelman-Sundberg, Kyung-Jin Jang, David R Jones, Volker M Lauschke,[...]. Annu Rev Pharmacol Toxicol 2018
74
50

Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework.
David Cook, Dearg Brown, Robert Alexander, Ruth March, Paul Morgan, Gemma Satterthwaite, Menelas N Pangalos. Nat Rev Drug Discov 2014
716
50

Cellular imaging predictions of clinical drug-induced liver injury.
Jinghai J Xu, Peter V Henstock, Margaret C Dunn, Arthur R Smith, Jeffrey R Chabot, David de Graaf. Toxicol Sci 2008
340
50

Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions.
Sabine U Vorrink, Yitian Zhou, Magnus Ingelman-Sundberg, Volker M Lauschke. Toxicol Sci 2018
95
50

Multi-cell type human liver microtissues for hepatotoxicity testing.
S Messner, I Agarkova, W Moritz, J M Kelm. Arch Toxicol 2013
206
50

Microengineered cultures containing human hepatic stellate cells and hepatocytes for drug development.
Matthew D Davidson, David A Kukla, Salman R Khetani. Integr Biol (Camb) 2017
35
50

Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury.
William R Proctor, Alison J Foster, Jennifer Vogt, Claire Summers, Brian Middleton, Mark A Pilling, Daniel Shienson, Monika Kijanska, Simon Ströbel, Jens M Kelm,[...]. Arch Toxicol 2017
143
50

Establishment of a hepatocyte-kupffer cell coculture model for assessment of proinflammatory cytokine effects on metabolizing enzymes and drug transporters.
Theresa V Nguyen, Okechukwu Ukairo, Salman R Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu, Raymond Evers. Drug Metab Dispos 2015
84
50


Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolites.
Wendy WeiWei Wang, Salman R Khetani, Stacy Krzyzewski, David B Duignan, R Scott Obach. Drug Metab Dispos 2010
102
50

Use of micropatterned cocultures to detect compounds that cause drug-induced liver injury in humans.
Salman R Khetani, Chitra Kanchagar, Okechukwu Ukairo, Stacy Krzyzewski, Amanda Moore, Julianne Shi, Simon Aoyama, Michael Aleo, Yvonne Will. Toxicol Sci 2013
141
50

Human hepatic 3D spheroids as a model for steatosis and insulin resistance.
Mikael Kozyra, Inger Johansson, Åsa Nordling, Shahid Ullah, Volker M Lauschke, Magnus Ingelman-Sundberg. Sci Rep 2018
78
50

3D Primary Hepatocyte Culture Systems for Analyses of Liver Diseases, Drug Metabolism, and Toxicity: Emerging Culture Paradigms and Applications.
Volker M Lauschke, Reza Z Shafagh, Delilah F G Hendriks, Magnus Ingelman-Sundberg. Biotechnol J 2019
62
50

Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability.
Delilah F G Hendriks, Lisa Fredriksson Puigvert, Simon Messner, Wolfgang Mortiz, Magnus Ingelman-Sundberg. Sci Rep 2016
91
40

Predicting circulating human metabolites: how good are we?
Shelby Anderson, Debra Luffer-Atlas, Mary Pat Knadler. Chem Res Toxicol 2009
76
40

Assessment of three human in vitro systems in the generation of major human excretory and circulating metabolites.
Deepak Dalvie, R Scott Obach, Ping Kang, Chandra Prakash, Cho-Ming Loi, Susan Hurst, Angus Nedderman, Lance Goulet, Evan Smith, Hai-Zhi Bu,[...]. Chem Res Toxicol 2009
122
40

Transcriptomic, Proteomic, and Functional Long-Term Characterization of Multicellular Three-Dimensional Human Liver Microtissues.
Simon Messner, Lisa Fredriksson, Volker M Lauschke, Katrin Roessger, Claudia Escher, Magdalena Bober, Jens M Kelm, Magnus Ingelman-Sundberg, Wolfgang Moritz. Appl In Vitro Toxicol 2018
29
40

A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.
Rowena L Sison-Young, Volker M Lauschke, Esther Johann, Eliane Alexandre, Sébastien Antherieu, Hélène Aerts, Helga H J Gerets, Gilles Labbe, Delphine Hoët, Martina Dorau,[...]. Arch Toxicol 2017
62
40

Human liver cell spheroids in extended perfusion bioreactor culture for repeated-dose drug testing.
Rui M Tostões, Sofia B Leite, Margarida Serra, Janne Jensen, Petter Björquist, Manuel J T Carrondo, Catarina Brito, Paula M Alves. Hepatology 2012
139
40

A comparison of whole genome gene expression profiles of HepaRG cells and HepG2 cells to primary human hepatocytes and human liver tissues.
Steven N Hart, Ye Li, Kaori Nakamoto, Eva-anne Subileau, David Steen, Xiao-bo Zhong. Drug Metab Dispos 2010
178
40

Perfused multiwell plate for 3D liver tissue engineering.
Karel Domansky, Walker Inman, James Serdy, Ajit Dash, Matthew H M Lim, Linda G Griffith. Lab Chip 2010
289
40

3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing.
Kazuo Takayama, Kenji Kawabata, Yasuhito Nagamoto, Keisuke Kishimoto, Katsuhisa Tashiro, Fuminori Sakurai, Masashi Tachibana, Katsuhiro Kanda, Takao Hayakawa, Miho Kusuda Furue,[...]. Biomaterials 2013
182
40

Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro.
Deborah G Nguyen, Juergen Funk, Justin B Robbins, Candace Crogan-Grundy, Sharon C Presnell, Thomas Singer, Adrian B Roth. PLoS One 2016
196
40

Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems.
Felipe T Lee-Montiel, Subin M George, Albert H Gough, Anup D Sharma, Juanfang Wu, Richard DeBiasio, Lawrence A Vernetti, D Lansing Taylor. Exp Biol Med (Maywood) 2017
76
40

Prediction of Drug Clearance and Drug-Drug Interactions in Microscale Cultures of Human Hepatocytes.
Christine Lin, Julianne Shi, Amanda Moore, Salman R Khetani. Drug Metab Dispos 2016
58
40

Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction.
Marcella Martignoni, Geny M M Groothuis, Ruben de Kanter. Expert Opin Drug Metab Toxicol 2006
924
40

Evaluation of human hepatocytes cultured by three-dimensional spheroid systems for drug metabolism.
Takako Ohkura, Kunihiro Ohta, Takuya Nagao, Kumiko Kusumoto, Akiko Koeda, Tadayoshi Ueda, Tomoko Jomura, Takeshi Ikeya, Emiko Ozeki, Kazuki Wada,[...]. Drug Metab Pharmacokinet 2014
47
40

Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis.
Leah M Norona, Deborah G Nguyen, David A Gerber, Sharon C Presnell, Merrie Mosedale, Paul B Watkins. PLoS One 2019
32
40

Exploring Chronic Drug Effects on Microengineered Human Liver Cultures Using Global Gene Expression Profiling.
Brenton R Ware, Michael McVay, Wendy Y Sunada, Salman R Khetani. Toxicol Sci 2017
15
40

Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.
Alison J Foster, Bhavik Chouhan, Sophie L Regan, Helen Rollison, Sara Amberntsson, Linda C Andersson, Abhishek Srivastava, Malin Darnell, Jonathan Cairns, Stanley E Lazic,[...]. Arch Toxicol 2019
51
40

A microfluidic hepatic coculture platform for cell-based drug metabolism studies.
Eric Novik, Timothy J Maguire, Piyun Chao, K C Cheng, Martin L Yarmush. Biochem Pharmacol 2010
141
40



Functionally Enhanced Human Stem Cell Derived Hepatocytes in Galactosylated Cellulosic Sponges for Hepatotoxicity Testing.
Farah Tasnim, Yi-Chin Toh, Yinghua Qu, Huan Li, Derek Phan, Balakrishnan C Narmada, Abhishek Ananthanarayanan, Nikhil Mittal, Ryan Q Meng, Hanry Yu. Mol Pharm 2016
31
40


Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development.
Kacey Ronaldson-Bouchard, Gordana Vunjak-Novakovic. Cell Stem Cell 2018
305
30

Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip.
Yu Du, Ning Li, Hao Yang, Chunhua Luo, Yixin Gong, Chunfang Tong, Yuxin Gao, Shouqin Lü, Mian Long. Lab Chip 2017
102
30

Three-dimensional co-culture of human hepatocytes and mesenchymal stem cells: improved functionality in long-term bioreactor cultures.
Sofia P Rebelo, Rita Costa, Marta M Silva, Paulo Marcelino, Catarina Brito, Paula M Alves. J Tissue Eng Regen Med 2017
46
30

Perfused human hepatocyte microtissues identify reactive metabolite-forming and mitochondria-perturbing hepatotoxins.
Cliff Rowe, Mohsen Shaeri, Emma Large, Terri Cornforth, Angela Robinson, Tomasz Kostrzewski, Rowena Sison-Young, Christopher Goldring, Kevin Park, David Hughes. Toxicol In Vitro 2018
16
30

Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis.
Ryan E Feaver, Banumathi K Cole, Mark J Lawson, Stephen A Hoang, Svetlana Marukian, Brett R Blackman, Robert A Figler, Arun J Sanyal, Brian R Wamhoff, Ajit Dash. JCI Insight 2016
79
30


A human liver microphysiology platform for investigating physiology, drug safety, and disease models.
Lawrence A Vernetti, Nina Senutovitch, Robert Boltz, Richard DeBiasio, Tong Ying Shun, Albert Gough, D Lansing Taylor. Exp Biol Med (Maywood) 2016
134
30

Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes.
Melissa Baxter, Sarah Withey, Sean Harrison, Charis-Patricia Segeritz, Fang Zhang, Rebecca Atkinson-Dell, Cliff Rowe, Dave T Gerrard, Rowena Sison-Young, Roz Jenkins,[...]. J Hepatol 2015
209
30


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.