A citation-based method for searching scientific literature

David Ramírez, Rafael Zúñiga, Guierdy Concha, Leandro Zúñiga. Molecules 2018
Times Cited: 10







List of co-cited articles
43 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Hyperpolarization-activated cation channels: from genes to function.
Martin Biel, Christian Wahl-Schott, Stylianos Michalakis, Xiangang Zong. Physiol Rev 2009
626
60

Exploring HCN channels as novel drug targets.
Otilia Postea, Martin Biel. Nat Rev Drug Discov 2011
136
50

Inflammatory and neuropathic pain are rapidly suppressed by peripheral block of hyperpolarisation-activated cyclic nucleotide-gated ion channels.
Gareth T Young, Edward C Emery, Elizabeth R Mooney, Christoforos Tsantoulas, Peter A McNaughton. Pain 2014
66
40

HCN2 ion channels play a central role in inflammatory and neuropathic pain.
Edward C Emery, Gareth T Young, Esther M Berrocoso, Lubin Chen, Peter A McNaughton. Science 2011
212
40

HCN2 ion channels: an emerging role as the pacemakers of pain.
Edward C Emery, Gareth T Young, Peter A McNaughton. Trends Pharmacol Sci 2012
72
30

Dysfunctional HCN ion channels in neurological diseases.
Jacopo C DiFrancesco, Dario DiFrancesco. Front Cell Neurosci 2015
69
30

HCN channels: function and clinical implications.
Eduardo E Benarroch. Neurology 2013
117
30

The hyperpolarization-activated cyclic nucleotide-gated 4 channel as a potential anti-seizure drug target.
Qays Kharouf, A Marie Phillips, Lauren E Bleakley, Emma Morrisroe, Julia Oyrer, Linghan Jia, Andreas Ludwig, Liang Jin, Joseph A Nicolazzo, Elisabetta Cerbai,[...]. Br J Pharmacol 2020
6
50

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2.
Andreas Ludwig, Thomas Budde, Juliane Stieber, Sven Moosmang, Christian Wahl, Knut Holthoff, Anke Langebartels, Carsten Wotjak, Thomas Munsch, Xiangang Zong,[...]. EMBO J 2003
371
30

Gabapentin Modulates HCN4 Channel Voltage-Dependence.
Han-Shen Tae, Kelly M Smith, A Marie Phillips, Kieran A Boyle, Melody Li, Ian C Forster, Robert J Hatch, Robert Richardson, David I Hughes, Brett A Graham,[...]. Front Pharmacol 2017
16
30

Ih blockers have a potential of antiepileptic effects.
Masaomi Kitayama, Harue Miyata, Michiko Yano, Nobuko Saito, Yoshiki Matsuda, Toshio Yamauchi, Shinichi Kogure. Epilepsia 2003
25
30

HCN Channels Modulators: The Need for Selectivity.
Maria Novella Romanelli, Laura Sartiani, Alessio Masi, Guido Mannaioni, Dina Manetti, Alessandro Mugelli, Elisabetta Cerbai. Curr Top Med Chem 2016
35
30


Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain.
Sandra R Chaplan, Hong-Qing Guo, Doo Hyun Lee, Lin Luo, Changlu Liu, Chester Kuei, Alexander A Velumian, Matthew P Butler, Sean M Brown, Adrienne E Dubin. J Neurosci 2003
230
20

HCN3 ion channels: roles in sensory neuronal excitability and pain.
Sergio Lainez, Christoforos Tsantoulas, Martin Biel, Peter A McNaughton. J Physiol 2019
11
20

Flavonoid regulation of HCN2 channels.
Anne E Carlson, Joel C Rosenbaum, Tinatin I Brelidze, Rachel E Klevit, William N Zagotta. J Biol Chem 2013
10
20

Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) ion channels drive pain in mouse models of diabetic neuropathy.
Christoforos Tsantoulas, Sergio Laínez, Sara Wong, Ishita Mehta, Bruno Vilar, Peter A McNaughton. Sci Transl Med 2017
45
20

Neurophysiology of HCN channels: from cellular functions to multiple regulations.
Chao He, Fang Chen, Bo Li, Zhian Hu. Prog Neurobiol 2014
184
20

Ivabradine (a hyperpolarization activated cyclic nucleotide-gated channel blocker) elevates the threshold for maximal electroshock-induced tonic seizures in mice.
Jarogniew J Luszczki, Andrzej Prystupa, Marta Andres-Mach, Ewa Marzęda, Magdalena Florek-Łuszczki. Pharmacol Rep 2013
19
20

The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells.
Matthew F Nolan, Gaël Malleret, Ka Hung Lee, Emma Gibbs, Joshua T Dudman, Bina Santoro, Deqi Yin, Richard F Thompson, Steven A Siegelbaum, Eric R Kandel,[...]. Cell 2003
230
20


Ivabradine possesses anticonvulsant and neuroprotective action in mice.
Talita Matias Barbosa Cavalcante, José de Maria Albuquerque De Melo, Lia Bastos Lopes, Matheus Costa Bessa, Jéssica Gurgel Santos, Luna Costa Vasconcelos, Antônio Eufrásio Vieira Neto, Lucas Teixeira Nunes Borges, Marta Maria França Fonteles, Adriano José Maia Chaves Filho,[...]. Biomed Pharmacother 2019
10
20

Local anesthetic inhibits hyperpolarization-activated cationic currents.
Qing-Tao Meng, Zhong-Yuan Xia, Jin Liu, Douglas A Bayliss, Xiangdong Chen. Mol Pharmacol 2011
26
20

Selective Blockade of HCN1/HCN2 Channels as a Potential Pharmacological Strategy Against Pain.
Leonardo Dini, Martina Del Lungo, Francesco Resta, Michele Melchiorre, Valentina Spinelli, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Annunziatina Laurino, Laura Sartiani, Raffaele Coppini,[...]. Front Pharmacol 2018
23
20


The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System.
Mehrnoush Zobeiri, Rahul Chaudhary, Anne Blaich, Matthias Rottmann, Stefan Herrmann, Patrick Meuth, Pawan Bista, Tatyana Kanyshkova, Annika Lüttjohann, Venu Narayanan,[...]. Cereb Cortex 2019
22
20

Decreases in HCN mRNA expression in the hippocampus after kindling and status epilepticus in adult rats.
Kim L Powell, Caroline Ng, Terence J O'Brien, Sheng Hong Xu, David A Williams, Simon J Foote, Christopher A Reid. Epilepsia 2008
64
20

Augmented currents of an HCN2 variant in patients with febrile seizure syndromes.
Leanne M Dibbens, Christopher A Reid, Bree Hodgson, Evan A Thomas, Alison M Phillips, Elena Gazina, Brett A Cromer, Alison L Clarke, Tallie Z Baram, Ingrid E Scheffer,[...]. Ann Neurol 2010
73
20

Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures.
Verena Hammelmann, Marc Sebastian Stieglitz, Henrik Hülle, Karim Le Meur, Jennifer Kass, Manuela Brümmer, Christian Gruner, René Dominik Rötzer, Stefanie Fenske, Jana Hartmann,[...]. JCI Insight 2019
10
20

Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue.
Martina Del Lungo, Michele Melchiorre, Luca Guandalini, Laura Sartiani, Alessandro Mugelli, Istvan Koncz, Tamas Szel, Andras Varro, Maria Novella Romanelli, Elisabetta Cerbai. Br J Pharmacol 2012
31
20

EC18 as a Tool To Understand the Role of HCN4 Channels in Mediating Hyperpolarization-Activated Current in Tissues.
Maria Novella Romanelli, Martina Del Lungo, Luca Guandalini, Mehrnoush Zobeiri, András Gyökeres, Tamás Árpádffy-Lovas, Istvan Koncz, Laura Sartiani, Gianluca Bartolucci, Silvia Dei,[...]. ACS Med Chem Lett 2019
6
33


Design, synthesis, and preliminary biological evaluation of new isoform-selective f-current blockers.
Michele Melchiorre, Martina Del Lungo, Luca Guandalini, Elisabetta Martini, Silvia Dei, Dina Manetti, Serena Scapecchi, Elisabetta Teodori, Laura Sartiani, Alessandro Mugelli,[...]. J Med Chem 2010
25
20

HCN1 mutation spectrum: from neonatal epileptic encephalopathy to benign generalized epilepsy and beyond.
Carla Marini, Alessandro Porro, Agnès Rastetter, Carine Dalle, Ilaria Rivolta, Daniel Bauer, Renske Oegema, Caroline Nava, Elena Parrini, Davide Mei,[...]. Brain 2018
34
20

Cardiac and neuronal HCN channelopathies.
Ilaria Rivolta, Anna Binda, Alessio Masi, Jacopo C DiFrancesco. Pflugers Arch 2020
14
20

Identification of the molecular site of ivabradine binding to HCN4 channels.
Annalisa Bucchi, Mirko Baruscotti, Marco Nardini, Andrea Barbuti, Stefano Micheloni, Martino Bolognesi, Dario DiFrancesco. PLoS One 2013
37
20

Testing broad-spectrum and isoform-preferring HCN channel blockers for anticonvulsant properties in mice.
Qays Kharouf, Paulo Pinares-Garcia, M Novella Romanelli, Christopher A Reid. Epilepsy Res 2020
2
100

Increased HCN Channel Activity in the Gasserian Ganglion Contributes to Trigeminal Neuropathic Pain.
Weihua Ding, Zerong You, Shiqian Shen, Jinsheng Yang, Grewo Lim, Jason T Doheny, Shengmei Zhu, Yi Zhang, Lucy Chen, Jianren Mao. J Pain 2018
8
25

Characterization of the human HCN1 channel and its inhibition by capsazepine.
Catherine H Gill, Andrew Randall, Stewart A Bates, Kerstin Hill, Davina Owen, Phil M Larkman, William Cairns, Shahnaz P Yusaf, Paul R Murdock, Paul J L M Strijbos,[...]. Br J Pharmacol 2004
43
20

Molecular mapping of the binding site for a blocker of hyperpolarization-activated, cyclic nucleotide-modulated pacemaker channels.
Lan Cheng, Krista Kinard, Ramkumar Rajamani, Michael C Sanguinetti. J Pharmacol Exp Ther 2007
38
20

Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine.
Annalisa Bucchi, Mirko Baruscotti, Dario DiFrancesco. J Gen Physiol 2002
188
20

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain.
B Santoro, D T Liu, H Yao, D Bartsch, E R Kandel, S A Siegelbaum, G R Tibbs. Cell 1998
549
20

Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis.
Zhuo Huang, Matthew C Walker, Mala M Shah. J Neurosci 2009
114
20

Estrogen enhances neurogenesis and behavioral recovery after stroke.
Jun Li, Matt Siegel, Mike Yuan, Zhiyuan Zeng, Laura Finnucan, Rebecca Persky, Patricia D Hurn, Louise D McCullough. J Cereb Blood Flow Metab 2011
100
10

Thiamine triphosphatase and the CYTH superfamily of proteins.
Lucien Bettendorff, Pierre Wins. FEBS J 2013
19
10

Hypermethylated in cancer 1(HIC1) suppresses non-small cell lung cancer progression by targeting interleukin-6/Stat3 pathway.
Xiumin Wang, Yingying Wang, Gang Xiao, Jinglong Wang, Lidong Zu, Mingang Hao, Xueqing Sun, Yujie Fu, Guohong Hu, Jianhua Wang. Oncotarget 2016
15
10

Four and a half LIM domain protein signaling and cardiomyopathy.
Yan Liang, William H Bradford, Jing Zhang, Farah Sheikh. Biophys Rev 2018
19
10

Knockout mice and dirty drugs. Drug addiction.
G R Uhl, D J Vandenbergh, L L Miner. Curr Biol 1996
23
10

Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression.
D M Donovan, L L Miner, M P Perry, R S Revay, L G Sharpe, S Przedborski, V Kostic, R M Philpot, C L Kirstein, R B Rothman,[...]. Brain Res Mol Brain Res 1999
68
10



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.