Seychelle M Vos, Lucas Farnung, Marc Boehning, Christoph Wigge, Andreas Linden, Henning Urlaub, Patrick Cramer. Nature 2018
Times Cited: 185
Times Cited: 185
Times Cited
Times Co-cited
Similarity
Structure of paused transcription complex Pol II-DSIF-NELF.
Seychelle M Vos, Lucas Farnung, Henning Urlaub, Patrick Cramer. Nature 2018
Seychelle M Vos, Lucas Farnung, Henning Urlaub, Patrick Cramer. Nature 2018
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Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation.
Leighton Core, Karen Adelman. Genes Dev 2019
Leighton Core, Karen Adelman. Genes Dev 2019
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Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
Seychelle M Vos, Lucas Farnung, Andreas Linden, Henning Urlaub, Patrick Cramer. Nat Struct Mol Biol 2020
Seychelle M Vos, Lucas Farnung, Andreas Linden, Henning Urlaub, Patrick Cramer. Nat Struct Mol Biol 2020
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Born to run: control of transcription elongation by RNA polymerase II.
Fei Xavier Chen, Edwin R Smith, Ali Shilatifard. Nat Rev Mol Cell Biol 2018
Fei Xavier Chen, Edwin R Smith, Ali Shilatifard. Nat Rev Mol Cell Biol 2018
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Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp.
Carrie Bernecky, Jürgen M Plitzko, Patrick Cramer. Nat Struct Mol Biol 2017
Carrie Bernecky, Jürgen M Plitzko, Patrick Cramer. Nat Struct Mol Biol 2017
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RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II.
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NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release.
Yuki Aoi, Edwin R Smith, Avani P Shah, Emily J Rendleman, Stacy A Marshall, Ashley R Woodfin, Fei X Chen, Ramin Shiekhattar, Ali Shilatifard. Mol Cell 2020
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Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons.
Iris Jonkers, Hojoong Kwak, John T Lis. Elife 2014
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CDK9-dependent RNA polymerase II pausing controls transcription initiation.
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PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II.
Fei Xavier Chen, Ashley R Woodfin, Alessandro Gardini, Ryan A Rickels, Stacy A Marshall, Edwin R Smith, Ramin Shiekhattar, Ali Shilatifard. Cell 2015
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P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation.
Tomoko Yamada, Yuki Yamaguchi, Naoto Inukai, Sachiko Okamoto, Takashi Mura, Hiroshi Handa. Mol Cell 2006
Tomoko Yamada, Yuki Yamaguchi, Naoto Inukai, Sachiko Okamoto, Takashi Mura, Hiroshi Handa. Mol Cell 2006
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Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans.
Karen Adelman, John T Lis. Nat Rev Genet 2012
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Paf1C regulates RNA polymerase II progression by modulating elongation rate.
Liming Hou, Yating Wang, Yu Liu, Nan Zhang, Ilya Shamovsky, Evgeny Nudler, Bin Tian, Brian David Dynlacht. Proc Natl Acad Sci U S A 2019
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c-Myc regulates transcriptional pause release.
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DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs.
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Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a "Sitting Duck Torpedo" Mechanism.
Michael A Cortazar, Ryan M Sheridan, Benjamin Erickson, Nova Fong, Kira Glover-Cutter, Kristopher Brannan, David L Bentley. Mol Cell 2019
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Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence.
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A Cdk9-PP1 switch regulates the elongation-termination transition of RNA polymerase II.
Pabitra K Parua, Gregory T Booth, Miriam Sansó, Bradley Benjamin, Jason C Tanny, John T Lis, Robert P Fisher. Nature 2018
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The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain.
Kevin M Harlen, L Stirling Churchman. Nat Rev Mol Cell Biol 2017
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Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing.
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Getting up to speed with transcription elongation by RNA polymerase II.
Iris Jonkers, John T Lis. Nat Rev Mol Cell Biol 2015
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TT-seq maps the human transient transcriptome.
Björn Schwalb, Margaux Michel, Benedikt Zacher, Katja Frühauf, Carina Demel, Achim Tresch, Julien Gagneur, Patrick Cramer. Science 2016
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NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation.
Y Yamaguchi, T Takagi, T Wada, K Yano, A Furuya, S Sugimoto, J Hasegawa, H Handa. Cell 1999
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Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination.
Kai-Lieh Huang, David Jee, Chad B Stein, Nathan D Elrod, Telmo Henriques, Lauren G Mascibroda, David Baillat, William K Russell, Karen Adelman, Eric J Wagner. Mol Cell 2020
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Distinct Cdk9-phosphatase switches act at the beginning and end of elongation by RNA polymerase II.
Pabitra K Parua, Sampada Kalan, Bradley Benjamin, Miriam Sansó, Robert P Fisher. Nat Commun 2020
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Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
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Paused RNA polymerase II inhibits new transcriptional initiation.
Wanqing Shao, Julia Zeitlinger. Nat Genet 2017
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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
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PAF1 regulation of promoter-proximal pause release via enhancer activation.
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The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.
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Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals.
Telmo Henriques, Daniel A Gilchrist, Sergei Nechaev, Michael Bern, Ginger W Muse, Adam Burkholder, David C Fargo, Karen Adelman. Mol Cell 2013
Telmo Henriques, Daniel A Gilchrist, Sergei Nechaev, Michael Bern, Ginger W Muse, Adam Burkholder, David C Fargo, Karen Adelman. Mol Cell 2013
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Precise maps of RNA polymerase reveal how promoters direct initiation and pausing.
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The Sequence Alignment/Map format and SAMtools.
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Structure of transcribing RNA polymerase II-nucleosome complex.
Lucas Farnung, Seychelle M Vos, Patrick Cramer. Nat Commun 2018
Lucas Farnung, Seychelle M Vos, Patrick Cramer. Nat Commun 2018
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Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Haruhiko Ehara, Tomoya Kujirai, Yuka Fujino, Mikako Shirouzu, Hitoshi Kurumizaka, Shun-Ichi Sekine. Science 2019
Haruhiko Ehara, Tomoya Kujirai, Yuka Fujino, Mikako Shirouzu, Hitoshi Kurumizaka, Shun-Ichi Sekine. Science 2019
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P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates.
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Genome-wide Single-Molecule Footprinting Reveals High RNA Polymerase II Turnover at Paused Promoters.
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Structure and mechanism of the RNA polymerase II transcription machinery.
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The Integrator Complex Attenuates Promoter-Proximal Transcription at Protein-Coding Genes.
Nathan D Elrod, Telmo Henriques, Kai-Lieh Huang, Deirdre C Tatomer, Jeremy E Wilusz, Eric J Wagner, Karen Adelman. Mol Cell 2019
Nathan D Elrod, Telmo Henriques, Kai-Lieh Huang, Deirdre C Tatomer, Jeremy E Wilusz, Eric J Wagner, Karen Adelman. Mol Cell 2019
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Evidence that Spt6p controls chromatin structure by a direct interaction with histones.
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The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Stephin J Vervoort, Sarah A Welsh, Jennifer R Devlin, Elisa Barbieri, Deborah A Knight, Sarah Offley, Stefan Bjelosevic, Matteo Costacurta, Izabela Todorovski, Conor J Kearney,[...]. Cell 2021
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Structure of the complete elongation complex of RNA polymerase II with basal factors.
Haruhiko Ehara, Takeshi Yokoyama, Hideki Shigematsu, Shigeyuki Yokoyama, Mikako Shirouzu, Shun-Ichi Sekine. Science 2017
Haruhiko Ehara, Takeshi Yokoyama, Hideki Shigematsu, Shigeyuki Yokoyama, Mikako Shirouzu, Shun-Ichi Sekine. Science 2017
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Widespread transcriptional pausing and elongation control at enhancers.
Telmo Henriques, Benjamin S Scruggs, Michiko O Inouye, Ginger W Muse, Lucy H Williams, Adam B Burkholder, Christopher A Lavender, David C Fargo, Karen Adelman. Genes Dev 2018
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.