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Times Cited: 365
Times Cited: 365
Times Cited
Times Co-cited
Similarity
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
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The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease.
Alicia M Pickrell, Richard J Youle. Neuron 2015
Alicia M Pickrell, Richard J Youle. Neuron 2015
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Mitochondrial DNA stress primes the antiviral innate immune response.
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A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
T Kitada, S Asakawa, N Hattori, H Matsumine, Y Yamamura, S Minoshima, M Yokochi, Y Mizuno, N Shimizu. Nature 1998
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Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.
Thomas G McWilliams, Alan R Prescott, Lambert Montava-Garriga, Graeme Ball, François Singh, Erica Barini, Miratul M K Muqit, Simon P Brooks, Ian G Ganley. Cell Metab 2018
Thomas G McWilliams, Alan R Prescott, Lambert Montava-Garriga, Graeme Ball, François Singh, Erica Barini, Miratul M K Muqit, Simon P Brooks, Ian G Ganley. Cell Metab 2018
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Parkinson's Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation.
Diana Matheoud, Ayumu Sugiura, Angélique Bellemare-Pelletier, Annie Laplante, Christiane Rondeau, Magali Chemali, Ali Fazel, John J Bergeron, Louis-Eric Trudeau, Yan Burelle,[...]. Cell 2016
Diana Matheoud, Ayumu Sugiura, Angélique Bellemare-Pelletier, Annie Laplante, Christiane Rondeau, Magali Chemali, Ali Fazel, John J Bergeron, Louis-Eric Trudeau, Yan Burelle,[...]. Cell 2016
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Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice.
Diana Matheoud, Tyler Cannon, Aurore Voisin, Anna-Maija Penttinen, Lauriane Ramet, Ahmed M Fahmy, Charles Ducrot, Annie Laplante, Marie-Josée Bourque, Lei Zhu,[...]. Nature 2019
Diana Matheoud, Tyler Cannon, Aurore Voisin, Anna-Maija Penttinen, Lauriane Ramet, Ahmed M Fahmy, Charles Ducrot, Annie Laplante, Marie-Josée Bourque, Lei Zhu,[...]. Nature 2019
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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.
Ira E Clark, Mark W Dodson, Changan Jiang, Joseph H Cao, Jun R Huh, Jae Hong Seol, Soon Ji Yoo, Bruce A Hay, Ming Guo. Nature 2006
Ira E Clark, Mark W Dodson, Changan Jiang, Joseph H Cao, Jun R Huh, Jae Hong Seol, Soon Ji Yoo, Bruce A Hay, Ming Guo. Nature 2006
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Hereditary early-onset Parkinson's disease caused by mutations in PINK1.
Enza Maria Valente, Patrick M Abou-Sleiman, Viviana Caputo, Miratul M K Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy,[...]. Science 2004
Enza Maria Valente, Patrick M Abou-Sleiman, Viviana Caputo, Miratul M K Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy,[...]. Science 2004
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Ubiquitin is phosphorylated by PINK1 to activate parkin.
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
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Mechanisms of mitophagy in cellular homeostasis, physiology and pathology.
Konstantinos Palikaras, Eirini Lionaki, Nektarios Tavernarakis. Nat Cell Biol 2018
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Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress.
Alicia M Pickrell, Chiu-Hui Huang, Scott R Kennedy, Alban Ordureau, Dionisia P Sideris, Jake G Hoekstra, J Wade Harper, Richard J Youle. Neuron 2015
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Measuring In Vivo Mitophagy.
Nuo Sun, Jeanho Yun, Jie Liu, Daniela Malide, Chengyu Liu, Ilsa I Rovira, Kira M Holmström, Maria M Fergusson, Young Hyun Yoo, Christian A Combs,[...]. Mol Cell 2015
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Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin.
Jeehye Park, Sung Bae Lee, Sungkyu Lee, Yongsung Kim, Saera Song, Sunhong Kim, Eunkyung Bae, Jaeseob Kim, Minho Shong, Jin-Man Kim,[...]. Nature 2006
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mito-QC illuminates mitophagy and mitochondrial architecture in vivo.
Thomas G McWilliams, Alan R Prescott, George F G Allen, Jevgenia Tamjar, Michael J Munson, Calum Thomson, Miratul M K Muqit, Ian G Ganley. J Cell Biol 2016
Thomas G McWilliams, Alan R Prescott, George F G Allen, Jevgenia Tamjar, Michael J Munson, Calum Thomson, Miratul M K Muqit, Ian G Ganley. J Cell Biol 2016
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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.
Sven Geisler, Kira M Holmström, Diana Skujat, Fabienne C Fiesel, Oliver C Rothfuss, Philipp J Kahle, Wolfdieter Springer. Nat Cell Biol 2010
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Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Anthony Rongvaux, Ruaidhrí Jackson, Christian C D Harman, Tuo Li, A Phillip West, Marcel R de Zoete, Youtong Wu, Brian Yordy, Saquib A Lakhani, Chia-Yi Kuan,[...]. Cell 2014
Anthony Rongvaux, Ruaidhrí Jackson, Christian C D Harman, Tuo Li, A Phillip West, Marcel R de Zoete, Youtong Wu, Brian Yordy, Saquib A Lakhani, Chia-Yi Kuan,[...]. Cell 2014
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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
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Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin.
Juliette J Lee, Alvaro Sanchez-Martinez, Aitor Martinez Zarate, Cristiane Benincá, Ugo Mayor, Michael J Clague, Alexander J Whitworth. J Cell Biol 2018
Juliette J Lee, Alvaro Sanchez-Martinez, Aitor Martinez Zarate, Cristiane Benincá, Ugo Mayor, Michael J Clague, Alexander J Whitworth. J Cell Biol 2018
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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
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PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Yun Chen, Gerald W Dorn. Science 2013
Yun Chen, Gerald W Dorn. Science 2013
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Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control.
Gian-Luca McLelland, Vincent Soubannier, Carol X Chen, Heidi M McBride, Edward A Fon. EMBO J 2014
Gian-Luca McLelland, Vincent Soubannier, Carol X Chen, Heidi M McBride, Edward A Fon. EMBO J 2014
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The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.
Baris Bingol, Joy S Tea, Lilian Phu, Mike Reichelt, Corey E Bakalarski, Qinghua Song, Oded Foreman, Donald S Kirkpatrick, Morgan Sheng. Nature 2014
Baris Bingol, Joy S Tea, Lilian Phu, Mike Reichelt, Corey E Bakalarski, Qinghua Song, Oded Foreman, Donald S Kirkpatrick, Morgan Sheng. Nature 2014
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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
M H Polymeropoulos, C Lavedan, E Leroy, S E Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer,[...]. Science 1997
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Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants.
Jessica C Greene, Alexander J Whitworth, Isabella Kuo, Laurie A Andrews, Mel B Feany, Leo J Pallanck. Proc Natl Acad Sci U S A 2003
Jessica C Greene, Alexander J Whitworth, Isabella Kuo, Laurie A Andrews, Mel B Feany, Leo J Pallanck. Proc Natl Acad Sci U S A 2003
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PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility.
Xinnan Wang, Dominic Winter, Ghazaleh Ashrafi, Julia Schlehe, Yao Liang Wong, Dennis Selkoe, Sarah Rice, Judith Steen, Matthew J LaVoie, Thomas L Schwarz. Cell 2011
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Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson's Disease.
Chung-Han Hsieh, Atossa Shaltouki, Ashley E Gonzalez, Alexandre Bettencourt da Cruz, Lena F Burbulla, Erica St Lawrence, Birgitt Schüle, Dimitri Krainc, Theo D Palmer, Xinnan Wang. Cell Stem Cell 2016
Chung-Han Hsieh, Atossa Shaltouki, Ashley E Gonzalez, Alexandre Bettencourt da Cruz, Lena F Burbulla, Erica St Lawrence, Birgitt Schüle, Dimitri Krainc, Theo D Palmer, Xinnan Wang. Cell Stem Cell 2016
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Mechanism of phospho-ubiquitin-induced PARKIN activation.
Tobias Wauer, Michal Simicek, Alexander Schubert, David Komander. Nature 2015
Tobias Wauer, Michal Simicek, Alexander Schubert, David Komander. Nature 2015
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Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
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Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons.
Matthew S Goldberg, Sheila M Fleming, James J Palacino, Carlos Cepeda, Hoa A Lam, Anushree Bhatnagar, Edward G Meloni, Nanping Wu, Larry C Ackerson, Gloria J Klapstein,[...]. J Biol Chem 2003
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Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.
Mike A Nalls, Cornelis Blauwendraat, Costanza L Vallerga, Karl Heilbron, Sara Bandres-Ciga, Diana Chang, Manuela Tan, Demis A Kia, Alastair J Noyce, Angli Xue,[...]. Lancet Neurol 2019
Mike A Nalls, Cornelis Blauwendraat, Costanza L Vallerga, Karl Heilbron, Sara Bandres-Ciga, Diana Chang, Manuela Tan, Demis A Kia, Alastair J Noyce, Angli Xue,[...]. Lancet Neurol 2019
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Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells.
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
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A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,[...]. Nat Immunol 2011
Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,[...]. Nat Immunol 2011
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Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
Alban Ordureau, Shireen A Sarraf, David M Duda, Jin-Mi Heo, Mark P Jedrychowski, Vladislav O Sviderskiy, Jennifer L Olszewski, James T Koerber, Tiao Xie, Sean A Beausoleil,[...]. Mol Cell 2014
Alban Ordureau, Shireen A Sarraf, David M Duda, Jin-Mi Heo, Mark P Jedrychowski, Vladislav O Sviderskiy, Jennifer L Olszewski, James T Koerber, Tiao Xie, Sean A Beausoleil,[...]. Mol Cell 2014
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PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease.
Joo-Ho Shin, Han Seok Ko, Hochul Kang, Yunjong Lee, Yun-Il Lee, Olga Pletinkova, Juan C Troconso, Valina L Dawson, Ted M Dawson. Cell 2011
Joo-Ho Shin, Han Seok Ko, Hochul Kang, Yunjong Lee, Yun-Il Lee, Olga Pletinkova, Juan C Troconso, Valina L Dawson, Ted M Dawson. Cell 2011
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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
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Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
Agne Kazlauskaite, Chandana Kondapalli, Robert Gourlay, David G Campbell, Maria Stella Ritorto, Kay Hofmann, Dario R Alessi, Axel Knebel, Matthias Trost, Miratul M K Muqit. Biochem J 2014
Agne Kazlauskaite, Chandana Kondapalli, Robert Gourlay, David G Campbell, Maria Stella Ritorto, Kay Hofmann, Dario R Alessi, Axel Knebel, Matthias Trost, Miratul M K Muqit. Biochem J 2014
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Loss of iron triggers PINK1/Parkin-independent mitophagy.
George F G Allen, Rachel Toth, John James, Ian G Ganley. EMBO Rep 2013
George F G Allen, Rachel Toth, John James, Ian G Ganley. EMBO Rep 2013
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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.
Hiroki Ishikawa, Glen N Barber. Nature 2008
Hiroki Ishikawa, Glen N Barber. Nature 2008
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Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
Shireen A Sarraf, Malavika Raman, Virginia Guarani-Pereira, Mathew E Sowa, Edward L Huttlin, Steven P Gygi, J Wade Harper. Nature 2013
Shireen A Sarraf, Malavika Raman, Virginia Guarani-Pereira, Mathew E Sowa, Edward L Huttlin, Steven P Gygi, J Wade Harper. Nature 2013
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Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
Michael J White, Kate McArthur, Donald Metcalf, Rachael M Lane, John C Cambier, Marco J Herold, Mark F van Delft, Sammy Bedoui, Guillaume Lessene, Matthew E Ritchie,[...]. Cell 2014
Michael J White, Kate McArthur, Donald Metcalf, Rachael M Lane, John C Cambier, Marco J Herold, Mark F van Delft, Sammy Bedoui, Guillaume Lessene, Matthew E Ritchie,[...]. Cell 2014
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Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.
Xiang Gui, Hui Yang, Tuo Li, Xiaojun Tan, Peiqing Shi, Minghao Li, Fenghe Du, Zhijian J Chen. Nature 2019
Xiang Gui, Hui Yang, Tuo Li, Xiaojun Tan, Peiqing Shi, Minghao Li, Fenghe Du, Zhijian J Chen. Nature 2019
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Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila.
Tom Cornelissen, Sven Vilain, Katlijn Vints, Natalia Gounko, Patrik Verstreken, Wim Vandenberghe. Elife 2018
Tom Cornelissen, Sven Vilain, Katlijn Vints, Natalia Gounko, Patrik Verstreken, Wim Vandenberghe. Elife 2018
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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.
Noriyuki Matsuda, Shigeto Sato, Kahori Shiba, Kei Okatsu, Keiko Saisho, Clement A Gautier, Yu-Shin Sou, Shinji Saiki, Sumihiro Kawajiri, Fumiaki Sato,[...]. J Cell Biol 2010
Noriyuki Matsuda, Shigeto Sato, Kahori Shiba, Kei Okatsu, Keiko Saisho, Clement A Gautier, Yu-Shin Sou, Shinji Saiki, Sumihiro Kawajiri, Fumiaki Sato,[...]. J Cell Biol 2010
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Mitochondrial DNA in innate immune responses and inflammatory pathology.
A Phillip West, Gerald S Shadel. Nat Rev Immunol 2017
A Phillip West, Gerald S Shadel. Nat Rev Immunol 2017
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.