Kaiwen W Chen, Mercedes Monteleone, Dave Boucher, Gabriel Sollberger, Divya Ramnath, Nicholas D Condon, Jessica B von Pein, Petr Broz, Matthew J Sweet, Kate Schroder. Sci Immunol 2018
Times Cited: 217
Times Cited: 217
Times Cited
Times Co-cited
Similarity
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps.
Gabriel Sollberger, Axel Choidas, Garth Lawrence Burn, Peter Habenberger, Raffaella Di Lucrezia, Susanne Kordes, Sascha Menninger, Jan Eickhoff, Peter Nussbaumer, Bert Klebl,[...]. Sci Immunol 2018
Gabriel Sollberger, Axel Choidas, Garth Lawrence Burn, Peter Habenberger, Raffaella Di Lucrezia, Susanne Kordes, Sascha Menninger, Jan Eickhoff, Peter Nussbaumer, Bert Klebl,[...]. Sci Immunol 2018
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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
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Neutrophil extracellular traps kill bacteria.
Volker Brinkmann, Ulrike Reichard, Christian Goosmann, Beatrix Fauler, Yvonne Uhlemann, David S Weiss, Yvette Weinrauch, Arturo Zychlinsky. Science 2004
Volker Brinkmann, Ulrike Reichard, Christian Goosmann, Beatrix Fauler, Yvonne Uhlemann, David S Weiss, Yvette Weinrauch, Arturo Zychlinsky. Science 2004
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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
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Pore-forming activity and structural autoinhibition of the gasdermin family.
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
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Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.
Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Shao. Nature 2017
Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Shao. Nature 2017
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Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death.
Hiroto Kambara, Fei Liu, Xiaoyu Zhang, Peng Liu, Besnik Bajrami, Yan Teng, Li Zhao, Shiyi Zhou, Hongbo Yu, Weidong Zhou,[...]. Cell Rep 2018
Hiroto Kambara, Fei Liu, Xiaoyu Zhang, Peng Liu, Besnik Bajrami, Yan Teng, Li Zhao, Shiyi Zhou, Hongbo Yu, Weidong Zhou,[...]. Cell Rep 2018
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The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
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Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
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Inflammatory caspases are innate immune receptors for intracellular LPS.
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Pontus Orning, Dan Weng, Kristian Starheim, Dmitry Ratner, Zachary Best, Bettina Lee, Alexandria Brooks, Shiyu Xia, Hao Wu, Michelle A Kelliher,[...]. Science 2018
Pontus Orning, Dan Weng, Kristian Starheim, Dmitry Ratner, Zachary Best, Bettina Lee, Alexandria Brooks, Shiyu Xia, Hao Wu, Michelle A Kelliher,[...]. Science 2018
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N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis.
Mausita Karmakar, Martin Minns, Elyse N Greenberg, Jose Diaz-Aponte, Kersi Pestonjamasp, Jennifer L Johnson, Joseph K Rathkey, Derek W Abbott, Kun Wang, Feng Shao,[...]. Nat Commun 2020
Mausita Karmakar, Martin Minns, Elyse N Greenberg, Jose Diaz-Aponte, Kersi Pestonjamasp, Jennifer L Johnson, Joseph K Rathkey, Derek W Abbott, Kun Wang, Feng Shao,[...]. Nat Commun 2020
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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
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ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation.
Sebastian Rühl, Kateryna Shkarina, Benjamin Demarco, Rosalie Heilig, José Carlos Santos, Petr Broz. Science 2018
Sebastian Rühl, Kateryna Shkarina, Benjamin Demarco, Rosalie Heilig, José Carlos Santos, Petr Broz. Science 2018
25
Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation.
Corey Rogers, Dan A Erkes, Alexandria Nardone, Andrew E Aplin, Teresa Fernandes-Alnemri, Emad S Alnemri. Nat Commun 2019
Corey Rogers, Dan A Erkes, Alexandria Nardone, Andrew E Aplin, Teresa Fernandes-Alnemri, Emad S Alnemri. Nat Commun 2019
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Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection.
Joseph Sarhan, Beiyun C Liu, Hayley I Muendlein, Peng Li, Rachael Nilson, Amy Y Tang, Anthony Rongvaux, Stephen C Bunnell, Feng Shao, Douglas R Green,[...]. Proc Natl Acad Sci U S A 2018
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Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.
Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S Alnemri. Nat Commun 2017
Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S Alnemri. Nat Commun 2017
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Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps.
Venizelos Papayannopoulos, Kathleen D Metzler, Abdul Hakkim, Arturo Zychlinsky. J Cell Biol 2010
Venizelos Papayannopoulos, Kathleen D Metzler, Abdul Hakkim, Arturo Zychlinsky. J Cell Biol 2010
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GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death.
Lorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill, Joka Pipercevic, Rosalie Heilig, Henning Stahlberg, Christopher J Farady, Daniel J Müller, Petr Broz, Sebastian Hiller. EMBO J 2016
Lorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill, Joka Pipercevic, Rosalie Heilig, Henning Stahlberg, Christopher J Farady, Daniel J Müller, Petr Broz, Sebastian Hiller. EMBO J 2016
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Novel cell death program leads to neutrophil extracellular traps.
Tobias A Fuchs, Ulrike Abed, Christian Goosmann, Robert Hurwitz, Ilka Schulze, Volker Wahn, Yvette Weinrauch, Volker Brinkmann, Arturo Zychlinsky. J Cell Biol 2007
Tobias A Fuchs, Ulrike Abed, Christian Goosmann, Robert Hurwitz, Ilka Schulze, Volker Wahn, Yvette Weinrauch, Volker Brinkmann, Arturo Zychlinsky. J Cell Biol 2007
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Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells.
Zhiwei Zhou, Huabin He, Kun Wang, Xuyan Shi, Yupeng Wang, Ya Su, Yao Wang, Da Li, Wang Liu, Yongliang Zhang,[...]. Science 2020
Zhiwei Zhou, Huabin He, Kun Wang, Xuyan Shi, Yupeng Wang, Ya Su, Yao Wang, Da Li, Wang Liu, Yongliang Zhang,[...]. Science 2020
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Neutrophil extracellular traps in immunity and disease.
Venizelos Papayannopoulos. Nat Rev Immunol 2018
Venizelos Papayannopoulos. Nat Rev Immunol 2018
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The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge.
Kaiwen W Chen, Christina J Groß, Flor Vásquez Sotomayor, Katryn J Stacey, Jurg Tschopp, Matthew J Sweet, Kate Schroder. Cell Rep 2014
Kaiwen W Chen, Christina J Groß, Flor Vásquez Sotomayor, Katryn J Stacey, Jurg Tschopp, Matthew J Sweet, Kate Schroder. Cell Rep 2014
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Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
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The gasdermins, a protein family executing cell death and inflammation.
Petr Broz, Pablo Pelegrín, Feng Shao. Nat Rev Immunol 2020
Petr Broz, Pablo Pelegrín, Feng Shao. Nat Rev Immunol 2020
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Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation.
Sabrina Sofia Burgener, Nathan Georges François Leborgne, Scott J Snipas, Guy S Salvesen, Phillip Ian Bird, Charaf Benarafa. Cell Rep 2019
Sabrina Sofia Burgener, Nathan Georges François Leborgne, Scott J Snipas, Guy S Salvesen, Phillip Ian Bird, Charaf Benarafa. Cell Rep 2019
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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
Jun Jacob Hu, Xing Liu, Shiyu Xia, Zhibin Zhang, Ying Zhang, Jingxia Zhao, Jianbin Ruan, Xuemei Luo, Xiwen Lou, Yang Bai,[...]. Nat Immunol 2020
Jun Jacob Hu, Xing Liu, Shiyu Xia, Zhibin Zhang, Ying Zhang, Jingxia Zhao, Jianbin Ruan, Xuemei Luo, Xiwen Lou, Yang Bai,[...]. Nat Immunol 2020
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PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps.
Pingxin Li, Ming Li, Michael R Lindberg, Mary J Kennett, Na Xiong, Yanming Wang. J Exp Med 2010
Pingxin Li, Ming Li, Michael R Lindberg, Mary J Kennett, Na Xiong, Yanming Wang. J Exp Med 2010
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Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
Zhibin Zhang, Ying Zhang, Shiyu Xia, Qing Kong, Shunying Li, Xing Liu, Caroline Junqueira, Karla F Meza-Sosa, Temy Mo Yin Mok, James Ansara,[...]. Nature 2020
Zhibin Zhang, Ying Zhang, Shiyu Xia, Qing Kong, Shunying Li, Xing Liu, Caroline Junqueira, Karla F Meza-Sosa, Temy Mo Yin Mok, James Ansara,[...]. Nature 2020
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GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes.
Robin A Aglietti, Alberto Estevez, Aaron Gupta, Monica Gonzalez Ramirez, Peter S Liu, Nobuhiko Kayagaki, Claudio Ciferri, Vishva M Dixit, Erin C Dueber. Proc Natl Acad Sci U S A 2016
Robin A Aglietti, Alberto Estevez, Aaron Gupta, Monica Gonzalez Ramirez, Peter S Liu, Nobuhiko Kayagaki, Claudio Ciferri, Vishva M Dixit, Erin C Dueber. Proc Natl Acad Sci U S A 2016
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Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
Nobuhiko Kayagaki, Michael T Wong, Irma B Stowe, Sree Ranjani Ramani, Lino C Gonzalez, Sachiko Akashi-Takamura, Kensuke Miyake, Juan Zhang, Wyne P Lee, Artur Muszyński,[...]. Science 2013
Nobuhiko Kayagaki, Michael T Wong, Irma B Stowe, Sree Ranjani Ramani, Lino C Gonzalez, Sachiko Akashi-Takamura, Kensuke Miyake, Juan Zhang, Wyne P Lee, Artur Muszyński,[...]. Science 2013
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Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Kun Wang, Qi Sun, Xiu Zhong, Mengxue Zeng, Huan Zeng, Xuyan Shi, Zilin Li, Yupeng Wang, Qiang Zhao, Feng Shao,[...]. Cell 2020
Kun Wang, Qi Sun, Xiu Zhong, Mengxue Zeng, Huan Zeng, Xuyan Shi, Zilin Li, Yupeng Wang, Qiang Zhao, Feng Shao,[...]. Cell 2020
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NINJ1 mediates plasma membrane rupture during lytic cell death.
Nobuhiko Kayagaki, Opher S Kornfeld, Bettina L Lee, Irma B Stowe, Karen O'Rourke, Qingling Li, Wendy Sandoval, Donghong Yan, Jing Kang, Min Xu,[...]. Nature 2021
Nobuhiko Kayagaki, Opher S Kornfeld, Bettina L Lee, Irma B Stowe, Karen O'Rourke, Qingling Li, Wendy Sandoval, Donghong Yan, Jing Kang, Min Xu,[...]. Nature 2021
19
SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology.
Flavio Protasio Veras, Marjorie Cornejo Pontelli, Camila Meirelles Silva, Juliana E Toller-Kawahisa, Mikhael de Lima, Daniele Carvalho Nascimento, Ayda Henriques Schneider, Diego Caetité, Lucas Alves Tavares, Isadora M Paiva,[...]. J Exp Med 2020
Flavio Protasio Veras, Marjorie Cornejo Pontelli, Camila Meirelles Silva, Juliana E Toller-Kawahisa, Mikhael de Lima, Daniele Carvalho Nascimento, Ayda Henriques Schneider, Diego Caetité, Lucas Alves Tavares, Isadora M Paiva,[...]. J Exp Med 2020
18
Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly.
Kaiwen W Chen, Benjamin Demarco, Rosalie Heilig, Kateryna Shkarina, Andreas Boettcher, Christopher J Farady, Pawel Pelczar, Petr Broz. EMBO J 2019
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Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages.
Cornelius Y Taabazuing, Marian C Okondo, Daniel A Bachovchin. Cell Chem Biol 2017
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SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx.
David Nobuhiro Douda, Meraj A Khan, Hartmut Grasemann, Nades Palaniyar. Proc Natl Acad Sci U S A 2015
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A myeloperoxidase-containing complex regulates neutrophil elastase release and actin dynamics during NETosis.
Kathleen D Metzler, Christian Goosmann, Aleksandra Lubojemska, Arturo Zychlinsky, Venizelos Papayannopoulos. Cell Rep 2014
Kathleen D Metzler, Christian Goosmann, Aleksandra Lubojemska, Arturo Zychlinsky, Venizelos Papayannopoulos. Cell Rep 2014
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A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus.
Florian H Pilsczek, Davide Salina, Karen K H Poon, Candace Fahey, Bryan G Yipp, Christopher D Sibley, Stephen M Robbins, Francis H Y Green, Mike G Surette, Motoyuki Sugai,[...]. J Immunol 2010
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17
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
Junwei Hou, Rongce Zhao, Weiya Xia, Chiung-Wen Chang, Yun You, Jung-Mao Hsu, Lei Nie, Yeh Chen, Yu-Chuan Wang, Chunxiao Liu,[...]. Nat Cell Biol 2020
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
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Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo.
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Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria.
José Carlos Santos, Dave Boucher, Larisa Kapinos Schneider, Benjamin Demarco, Marisa Dilucca, Kateryna Shkarina, Rosalie Heilig, Kaiwen W Chen, Roderick Y H Lim, Petr Broz. Nat Commun 2020
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Cryo-EM structure of the gasdermin A3 membrane pore.
Jianbin Ruan, Shiyu Xia, Xing Liu, Judy Lieberman, Hao Wu. Nature 2018
Jianbin Ruan, Shiyu Xia, Xing Liu, Judy Lieberman, Hao Wu. Nature 2018
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Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.
Christian Lood, Luz P Blanco, Monica M Purmalek, Carmelo Carmona-Rivera, Suk S De Ravin, Carolyne K Smith, Harry L Malech, Jeffrey A Ledbetter, Keith B Elkon, Mariana J Kaplan. Nat Med 2016
Christian Lood, Luz P Blanco, Monica M Purmalek, Carmelo Carmona-Rivera, Suk S De Ravin, Carolyne K Smith, Harry L Malech, Jeffrey A Ledbetter, Keith B Elkon, Mariana J Kaplan. Nat Med 2016
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Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps.
S Yousefi, C Mihalache, E Kozlowski, I Schmid, H U Simon. Cell Death Differ 2009
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Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation.
Yanming Wang, Ming Li, Sonja Stadler, Sarah Correll, Pingxin Li, Danchen Wang, Ryo Hayama, Lauriebeth Leonelli, Hyunsil Han, Sergei A Grigoryev,[...]. J Cell Biol 2009
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Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.
Jon A Hagar, Daniel A Powell, Youssef Aachoui, Robert K Ernst, Edward A Miao. Science 2013
Jon A Hagar, Daniel A Powell, Youssef Aachoui, Robert K Ernst, Edward A Miao. Science 2013
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Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Dave Boucher, Mercedes Monteleone, Rebecca C Coll, Kaiwen W Chen, Connie M Ross, Jessica L Teo, Guillermo A Gomez, Caroline L Holley, Damien Bierschenk, Katryn J Stacey,[...]. J Exp Med 2018
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14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.