Maja Sabol, Diana Trnski, Vesna Musani, Petar Ozretić, Sonja Levanat. Int J Mol Sci 2018
Times Cited: 32
Times Cited: 32
Times Cited
Times Co-cited
Similarity
Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.
Barbara Stecca, Christophe Mas, Virginie Clement, Marie Zbinden, Rafael Correa, Vincent Piguet, Friedrich Beermann, Ariel Ruiz i Altaba. Proc Natl Acad Sci U S A 2007
Barbara Stecca, Christophe Mas, Virginie Clement, Marie Zbinden, Rafael Correa, Vincent Piguet, Friedrich Beermann, Ariel Ruiz i Altaba. Proc Natl Acad Sci U S A 2007
25
Non-canonical Hedgehog Signaling Pathway in Cancer: Activation of GLI Transcription Factors Beyond Smoothened.
Silvia Pietrobono, Sinforosa Gagliardi, Barbara Stecca. Front Genet 2019
Silvia Pietrobono, Sinforosa Gagliardi, Barbara Stecca. Front Genet 2019
25
The GLI gene encodes a nuclear protein which binds specific sequences in the human genome.
K W Kinzler, B Vogelstein. Mol Cell Biol 1990
K W Kinzler, B Vogelstein. Mol Cell Biol 1990
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GSK3β and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3β downregulates the signaling pathway and reduces cell proliferation.
Diana Trnski, Maja Sabol, Ante Gojević, Marina Martinić, Petar Ozretić, Vesna Musani, Snježana Ramić, Sonja Levanat. Biochim Biophys Acta 2015
Diana Trnski, Maja Sabol, Ante Gojević, Marina Martinić, Petar Ozretić, Vesna Musani, Snježana Ramić, Sonja Levanat. Biochim Biophys Acta 2015
18
Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.
Matthias Lauth, Asa Bergström, Takashi Shimokawa, Rune Toftgård. Proc Natl Acad Sci U S A 2007
Matthias Lauth, Asa Bergström, Takashi Shimokawa, Rune Toftgård. Proc Natl Acad Sci U S A 2007
18
Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.
Pawel Niewiadomski, Jennifer H Kong, Robert Ahrends, Yan Ma, Eric W Humke, Sohini Khan, Mary N Teruel, Bennett G Novitch, Rajat Rohatgi. Cell Rep 2014
Pawel Niewiadomski, Jennifer H Kong, Robert Ahrends, Yan Ma, Eric W Humke, Sohini Khan, Mary N Teruel, Bennett G Novitch, Rajat Rohatgi. Cell Rep 2014
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A highlight on Sonic hedgehog pathway.
Gabriela Basile Carballo, Jéssica Ribeiro Honorato, Giselle Pinto Farias de Lopes, Tania Cristina Leite de Sampaio E Spohr. Cell Commun Signal 2018
Gabriela Basile Carballo, Jéssica Ribeiro Honorato, Giselle Pinto Farias de Lopes, Tania Cristina Leite de Sampaio E Spohr. Cell Commun Signal 2018
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Targeting GLI Transcription Factors in Cancer.
Miroslava Didiasova, Liliana Schaefer, Malgorzata Wygrecka. Molecules 2018
Miroslava Didiasova, Liliana Schaefer, Malgorzata Wygrecka. Molecules 2018
15
A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers.
Barbara Stecca, Ariel Ruiz i Altaba. EMBO J 2009
Barbara Stecca, Ariel Ruiz i Altaba. EMBO J 2009
15
The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
Ana Marija Skoda, Dora Simovic, Valentina Karin, Vedran Kardum, Semir Vranic, Ljiljana Serman. Bosn J Basic Med Sci 2018
Ana Marija Skoda, Dora Simovic, Valentina Karin, Vedran Kardum, Semir Vranic, Ljiljana Serman. Bosn J Basic Med Sci 2018
15
Hedgehog signaling in animal development: paradigms and principles.
P W Ingham, A P McMahon. Genes Dev 2001
P W Ingham, A P McMahon. Genes Dev 2001
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GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft.
Junsheng Fu, Mariana Rodova, Sanjit K Roy, Jay Sharma, Karan P Singh, Rakesh K Srivastava, Sharmila Shankar. Cancer Lett 2013
Junsheng Fu, Mariana Rodova, Sanjit K Roy, Jay Sharma, Karan P Singh, Rakesh K Srivastava, Sharmila Shankar. Cancer Lett 2013
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Gli Proteins: Regulation in Development and Cancer.
Paweł Niewiadomski, Sylwia M Niedziółka, Łukasz Markiewicz, Tomasz Uśpieński, Brygida Baran, Katarzyna Chojnowska. Cells 2019
Paweł Niewiadomski, Sylwia M Niedziółka, Łukasz Markiewicz, Tomasz Uśpieński, Brygida Baran, Katarzyna Chojnowska. Cells 2019
15
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
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Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
K J Livak, T D Schmittgen. Methods 2001
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Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.
Ziyu Zhang, Longyan Shen, Kelvin Law, Zengdi Zhang, Xiaotong Liu, Hu Hua, Sanen Li, Huijie Huang, Shen Yue, Chi-Chung Hui,[...]. Mol Cell Biol 2017
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12
FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer.
Bingchen Han, Ying Qu, Yanli Jin, Yi Yu, Nan Deng, Kolja Wawrowsky, Xiao Zhang, Na Li, Shikha Bose, Qiang Wang,[...]. Cell Rep 2015
Bingchen Han, Ying Qu, Yanli Jin, Yi Yu, Nan Deng, Kolja Wawrowsky, Xiao Zhang, Na Li, Shikha Bose, Qiang Wang,[...]. Cell Rep 2015
12
The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
12
Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway.
Sierra A Colavito, Mike R Zou, Qin Yan, Don X Nguyen, David F Stern. Breast Cancer Res 2014
Sierra A Colavito, Mike R Zou, Qin Yan, Don X Nguyen, David F Stern. Breast Cancer Res 2014
12
DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway.
Rajeev Singh, Pavan Kumar Dhanyamraju, Matthias Lauth. Oncotarget 2017
Rajeev Singh, Pavan Kumar Dhanyamraju, Matthias Lauth. Oncotarget 2017
12
GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.
Scott X Atwood, Mischa Li, Alex Lee, Jean Y Tang, Anthony E Oro. Nature 2013
Scott X Atwood, Mischa Li, Alex Lee, Jean Y Tang, Anthony E Oro. Nature 2013
12
Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.
Robert L Yauch, Gerrit J P Dijkgraaf, Bruno Alicke, Thomas Januario, Christina P Ahn, Thomas Holcomb, Kanan Pujara, Jeremy Stinson, Christopher A Callahan, Tracy Tang,[...]. Science 2009
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12
The crosstalk of mTOR/S6K1 and Hedgehog pathways.
Yan Wang, Qingqing Ding, Chia-Jui Yen, Weiya Xia, Julie G Izzo, Jing-Yu Lang, Chia-Wei Li, Jennifer L Hsu, Stephanie A Miller, Xuemei Wang,[...]. Cancer Cell 2012
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12
Roles for Hedgehog signaling in adult organ homeostasis and repair.
Ralitsa Petrova, Alexandra L Joyner. Development 2014
Ralitsa Petrova, Alexandra L Joyner. Development 2014
12
Targeting the Hedgehog pathway in cancer.
Sachin Gupta, Naoko Takebe, Patricia Lorusso. Ther Adv Med Oncol 2010
Sachin Gupta, Naoko Takebe, Patricia Lorusso. Ther Adv Med Oncol 2010
12
Hedgehog Signaling in the Maintenance of Cancer Stem Cells.
Catherine R Cochrane, Anette Szczepny, D Neil Watkins, Jason E Cain. Cancers (Basel) 2015
Catherine R Cochrane, Anette Szczepny, D Neil Watkins, Jason E Cain. Cancers (Basel) 2015
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Gli proteins in development and disease.
Chi-Chung Hui, Stephane Angers. Annu Rev Cell Dev Biol 2011
Chi-Chung Hui, Stephane Angers. Annu Rev Cell Dev Biol 2011
12
Hedgehog signaling pathway inhibitors: an updated patent review (2015-present).
Deborah Quaglio, Paola Infante, Lucia Di Marcotullio, Bruno Botta, Mattia Mori. Expert Opin Ther Pat 2020
Deborah Quaglio, Paola Infante, Lucia Di Marcotullio, Bruno Botta, Mattia Mori. Expert Opin Ther Pat 2020
22
Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system.
Yuhong Han, Yue Xiong, Xuanming Shi, Jiang Wu, Yun Zhao, Jin Jiang. PLoS Biol 2017
Yuhong Han, Yue Xiong, Xuanming Shi, Jiang Wu, Yun Zhao, Jin Jiang. PLoS Biol 2017
10
GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.
Olivier Nolan-Stevaux, Janet Lau, Morgan L Truitt, Gerald C Chu, Matthias Hebrok, Martin E Fernández-Zapico, Douglas Hanahan. Genes Dev 2009
Olivier Nolan-Stevaux, Janet Lau, Morgan L Truitt, Gerald C Chu, Matthias Hebrok, Martin E Fernández-Zapico, Douglas Hanahan. Genes Dev 2009
9
Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer.
Namrata Bora-Singhal, Deepak Perumal, Jonathan Nguyen, Srikumar Chellappan. Neoplasia 2015
Namrata Bora-Singhal, Deepak Perumal, Jonathan Nguyen, Srikumar Chellappan. Neoplasia 2015
9
Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions.
Dongsheng Gu, Jingwu Xie. Cancers (Basel) 2015
Dongsheng Gu, Jingwu Xie. Cancers (Basel) 2015
9
Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors.
Tadas K Rimkus, Richard L Carpenter, Shadi Qasem, Michael Chan, Hui-Wen Lo. Cancers (Basel) 2016
Tadas K Rimkus, Richard L Carpenter, Shadi Qasem, Michael Chan, Hui-Wen Lo. Cancers (Basel) 2016
9
A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome.
Yong Pan, Baolin Wang. J Biol Chem 2007
Yong Pan, Baolin Wang. J Biol Chem 2007
9
Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo.
Sylviane Dennler, Jocelyne André, Ismini Alexaki, Allen Li, Thierry Magnaldo, Peter ten Dijke, Xiao-Jing Wang, Franck Verrecchia, Alain Mauviel. Cancer Res 2007
Sylviane Dennler, Jocelyne André, Ismini Alexaki, Allen Li, Thierry Magnaldo, Peter ten Dijke, Xiao-Jing Wang, Franck Verrecchia, Alain Mauviel. Cancer Res 2007
9
SPOP suppresses tumorigenesis by regulating Hedgehog/Gli2 signaling pathway in gastric cancer.
Chunyan Zeng, Yao Wang, Quqin Lu, Jiang Chen, Junyan Zhang, Tao Liu, Nonghua Lv, Shiwen Luo. J Exp Clin Cancer Res 2014
Chunyan Zeng, Yao Wang, Quqin Lu, Jiang Chen, Junyan Zhang, Tao Liu, Nonghua Lv, Shiwen Luo. J Exp Clin Cancer Res 2014
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The Hedgehog signal transduction network.
David J Robbins, Dennis Liang Fei, Natalia A Riobo. Sci Signal 2012
David J Robbins, Dennis Liang Fei, Natalia A Riobo. Sci Signal 2012
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A paracrine requirement for hedgehog signalling in cancer.
Robert L Yauch, Stephen E Gould, Suzie J Scales, Tracy Tang, Hua Tian, Christina P Ahn, Derek Marshall, Ling Fu, Thomas Januario, Dara Kallop,[...]. Nature 2008
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9
Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1.
P Kogerman, T Grimm, L Kogerman, D Krause, A B Undén, B Sandstedt, R Toftgård, P G Zaphiropoulos. Nat Cell Biol 1999
P Kogerman, T Grimm, L Kogerman, D Krause, A B Undén, B Sandstedt, R Toftgård, P G Zaphiropoulos. Nat Cell Biol 1999
9
Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells.
Joseph L Regan, Dirk Schumacher, Stephanie Staudte, Andreas Steffen, Johannes Haybaeck, Ulrich Keilholz, Caroline Schweiger, Nicole Golob-Schwarzl, Dominik Mumberg, David Henderson,[...]. Cell Rep 2017
Joseph L Regan, Dirk Schumacher, Stephanie Staudte, Andreas Steffen, Johannes Haybaeck, Ulrich Keilholz, Caroline Schweiger, Nicole Golob-Schwarzl, Dominik Mumberg, David Henderson,[...]. Cell Rep 2017
9
Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.
Chengbing Wang, Yong Pan, Baolin Wang. Development 2010
Chengbing Wang, Yong Pan, Baolin Wang. Development 2010
9
Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.
Xiaohui Wen, Cary K Lai, Marie Evangelista, Jo-Anne Hongo, Frederic J de Sauvage, Suzie J Scales. Mol Cell Biol 2010
Xiaohui Wen, Cary K Lai, Marie Evangelista, Jo-Anne Hongo, Frederic J de Sauvage, Suzie J Scales. Mol Cell Biol 2010
9
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling.
H Sasaki, Y Nishizaki, C Hui, M Nakafuku, H Kondoh. Development 1999
H Sasaki, Y Nishizaki, C Hui, M Nakafuku, H Kondoh. Development 1999
9
In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
Monica Benvenuto, Laura Masuelli, Enrico De Smaele, Massimo Fantini, Rosanna Mattera, Danilo Cucchi, Elena Bonanno, Enrica Di Stefano, Giovanni Vanni Frajese, Augusto Orlandi,[...]. Oncotarget 2016
Monica Benvenuto, Laura Masuelli, Enrico De Smaele, Massimo Fantini, Rosanna Mattera, Danilo Cucchi, Elena Bonanno, Enrica Di Stefano, Giovanni Vanni Frajese, Augusto Orlandi,[...]. Oncotarget 2016
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Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells.
Zhenyu Ji, Fang C Mei, Jingwu Xie, Xiaodong Cheng. J Biol Chem 2007
Zhenyu Ji, Fang C Mei, Jingwu Xie, Xiaodong Cheng. J Biol Chem 2007
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GLI activates transcription through a herpes simplex viral protein 16-like activation domain.
J W Yoon, C Z Liu, J T Yang, R Swart, P Iannaccone, D Walterhouse. J Biol Chem 1998
J W Yoon, C Z Liu, J T Yang, R Swart, P Iannaccone, D Walterhouse. J Biol Chem 1998
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Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3.
P Dai, H Akimaru, Y Tanaka, T Maekawa, M Nakafuku, S Ishii. J Biol Chem 1999
P Dai, H Akimaru, Y Tanaka, T Maekawa, M Nakafuku, S Ishii. J Biol Chem 1999
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The Hedgehog's tale: developing strategies for targeting cancer.
Jessica M Y Ng, Tom Curran. Nat Rev Cancer 2011
Jessica M Y Ng, Tom Curran. Nat Rev Cancer 2011
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Hedgehog Signaling: From Basic Biology to Cancer Therapy.
Fujia Wu, Yu Zhang, Bo Sun, Andrew P McMahon, Yu Wang. Cell Chem Biol 2017
Fujia Wu, Yu Zhang, Bo Sun, Andrew P McMahon, Yu Wang. Cell Chem Biol 2017
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.