Nicoletta Machin, Margaret V Ragni. J Blood Med 2018
Times Cited: 44
Times Cited: 44
Times Cited
Times Co-cited
Similarity
Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy.
K John Pasi, Savita Rangarajan, Pencho Georgiev, Tim Mant, Michael D Creagh, Toshko Lissitchkov, David Bevan, Steve Austin, Charles R Hay, Inga Hegemann,[...]. N Engl J Med 2017
K John Pasi, Savita Rangarajan, Pencho Georgiev, Tim Mant, Michael D Creagh, Toshko Lissitchkov, David Bevan, Steve Austin, Charles R Hay, Inga Hegemann,[...]. N Engl J Med 2017
56
An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.
Alfica Sehgal, Scott Barros, Lacramioara Ivanciu, Brian Cooley, June Qin, Tim Racie, Julia Hettinger, Mary Carioto, Yongfeng Jiang, Josh Brodsky,[...]. Nat Med 2015
Alfica Sehgal, Scott Barros, Lacramioara Ivanciu, Brian Cooley, June Qin, Tim Racie, Julia Hettinger, Mary Carioto, Yongfeng Jiang, Josh Brodsky,[...]. Nat Med 2015
36
Emicizumab Prophylaxis in Patients Who Have Hemophilia A without Inhibitors.
Johnny Mahlangu, Johannes Oldenburg, Ido Paz-Priel, Claude Negrier, Markus Niggli, M Elisa Mancuso, Christophe Schmitt, Victor Jiménez-Yuste, Christine Kempton, Christophe Dhalluin,[...]. N Engl J Med 2018
Johnny Mahlangu, Johannes Oldenburg, Ido Paz-Priel, Claude Negrier, Markus Niggli, M Elisa Mancuso, Christophe Schmitt, Victor Jiménez-Yuste, Christine Kempton, Christophe Dhalluin,[...]. N Engl J Med 2018
29
Emicizumab Prophylaxis in Hemophilia A with Inhibitors.
Johannes Oldenburg, Johnny N Mahlangu, Benjamin Kim, Christophe Schmitt, Michael U Callaghan, Guy Young, Elena Santagostino, Rebecca Kruse-Jarres, Claude Negrier, Craig Kessler,[...]. N Engl J Med 2017
Johannes Oldenburg, Johnny N Mahlangu, Benjamin Kim, Christophe Schmitt, Michael U Callaghan, Guy Young, Elena Santagostino, Rebecca Kruse-Jarres, Claude Negrier, Craig Kessler,[...]. N Engl J Med 2017
29
Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis.
David Adams, Alejandra Gonzalez-Duarte, William D O'Riordan, Chih-Chao Yang, Mitsuharu Ueda, Arnt V Kristen, Ivailo Tournev, Hartmut H Schmidt, Teresa Coelho, John L Berk,[...]. N Engl J Med 2018
David Adams, Alejandra Gonzalez-Duarte, William D O'Riordan, Chih-Chao Yang, Mitsuharu Ueda, Arnt V Kristen, Ivailo Tournev, Hartmut H Schmidt, Teresa Coelho, John L Berk,[...]. N Engl J Med 2018
27
Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits robust RNAi-mediated gene silencing.
Jayaprakash K Nair, Jennifer L S Willoughby, Amy Chan, Klaus Charisse, Md Rowshon Alam, Qianfan Wang, Menno Hoekstra, Pachamuthu Kandasamy, Alexander V Kel'in, Stuart Milstein,[...]. J Am Chem Soc 2014
Jayaprakash K Nair, Jennifer L S Willoughby, Amy Chan, Klaus Charisse, Md Rowshon Alam, Qianfan Wang, Menno Hoekstra, Pachamuthu Kandasamy, Alexander V Kel'in, Stuart Milstein,[...]. J Am Chem Soc 2014
25
Safety and pharmacokinetics of anti-TFPI antibody (concizumab) in healthy volunteers and patients with hemophilia: a randomized first human dose trial.
P Chowdary, S Lethagen, U Friedrich, B Brand, C Hay, F Abdul Karim, R Klamroth, P Knoebl, M Laffan, J Mahlangu,[...]. J Thromb Haemost 2015
P Chowdary, S Lethagen, U Friedrich, B Brand, C Hay, F Abdul Karim, R Klamroth, P Knoebl, M Laffan, J Mahlangu,[...]. J Thromb Haemost 2015
25
Subcutaneous concizumab prophylaxis in hemophilia A and hemophilia A/B with inhibitors: phase 2 trial results.
Amy D Shapiro, Pantep Angchaisuksiri, Jan Astermark, Gary Benson, Giancarlo Castaman, Pratima Chowdary, Hermann Eichler, Victor Jiménez-Yuste, Kaan Kavakli, Tadashi Matsushita,[...]. Blood 2019
Amy D Shapiro, Pantep Angchaisuksiri, Jan Astermark, Gary Benson, Giancarlo Castaman, Pratima Chowdary, Hermann Eichler, Victor Jiménez-Yuste, Kaan Kavakli, Tadashi Matsushita,[...]. Blood 2019
25
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans.
A Fire, S Xu, M K Montgomery, S A Kostas, S E Driver, C C Mello. Nature 1998
A Fire, S Xu, M K Montgomery, S A Kostas, S E Driver, C C Mello. Nature 1998
20
Multiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A.
K John Pasi, Savita Rangarajan, Nina Mitchell, Will Lester, Emily Symington, Bella Madan, Michael Laffan, Chris B Russell, Mingjin Li, Glenn F Pierce,[...]. N Engl J Med 2020
K John Pasi, Savita Rangarajan, Nina Mitchell, Will Lester, Emily Symington, Bella Madan, Michael Laffan, Chris B Russell, Mingjin Li, Glenn F Pierce,[...]. N Engl J Med 2020
20
Guidelines for the management of hemophilia.
A Srivastava, A K Brewer, E P Mauser-Bunschoten, N S Key, S Kitchen, A Llinas, C A Ludlam, J N Mahlangu, K Mulder, M C Poon,[...]. Haemophilia 2013
A Srivastava, A K Brewer, E P Mauser-Bunschoten, N S Key, S Kitchen, A Llinas, C A Ludlam, J N Mahlangu, K Mulder, M C Poon,[...]. Haemophilia 2013
18
AAV5-Factor VIII Gene Transfer in Severe Hemophilia A.
Savita Rangarajan, Liron Walsh, Will Lester, David Perry, Bella Madan, Michael Laffan, Hua Yu, Christian Vettermann, Glenn F Pierce, Wing Y Wong,[...]. N Engl J Med 2017
Savita Rangarajan, Liron Walsh, Will Lester, David Perry, Bella Madan, Michael Laffan, Hua Yu, Christian Vettermann, Glenn F Pierce, Wing Y Wong,[...]. N Engl J Med 2017
18
A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model.
Takehisa Kitazawa, Tomoyuki Igawa, Zenjiro Sampei, Atsushi Muto, Tetsuo Kojima, Tetsuhiro Soeda, Kazutaka Yoshihashi, Yukiko Okuyama-Nishida, Hiroyuki Saito, Hiroyuki Tsunoda,[...]. Nat Med 2012
Takehisa Kitazawa, Tomoyuki Igawa, Zenjiro Sampei, Atsushi Muto, Tetsuo Kojima, Tetsuhiro Soeda, Kazutaka Yoshihashi, Yukiko Okuyama-Nishida, Hiroyuki Saito, Hiroyuki Tsunoda,[...]. Nat Med 2012
18
Inhibition of Tissue Factor Pathway Inhibitor (TFPI) as a Treatment for Haemophilia: Rationale with Focus on Concizumab.
Pratima Chowdary. Drugs 2018
Pratima Chowdary. Drugs 2018
29
Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?
Peter J Lenting, Cécile V Denis, Olivier D Christophe. Blood 2017
Peter J Lenting, Cécile V Denis, Olivier D Christophe. Blood 2017
18
Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non-randomised phase 3 study.
Steven W Pipe, Midori Shima, Michaela Lehle, Amy Shapiro, Sammy Chebon, Katsuyuki Fukutake, Nigel S Key, Agnès Portron, Christophe Schmitt, Maria Podolak-Dawidziak,[...]. Lancet Haematol 2019
Steven W Pipe, Midori Shima, Michaela Lehle, Amy Shapiro, Sammy Chebon, Katsuyuki Fukutake, Nigel S Key, Agnès Portron, Christophe Schmitt, Maria Podolak-Dawidziak,[...]. Lancet Haematol 2019
18
Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia.
Marilyn J Manco-Johnson, Thomas C Abshire, Amy D Shapiro, Brenda Riske, Michele R Hacker, Ray Kilcoyne, J David Ingram, Michael L Manco-Johnson, Sharon Funk, Linda Jacobson,[...]. N Engl J Med 2007
Marilyn J Manco-Johnson, Thomas C Abshire, Amy D Shapiro, Brenda Riske, Michele R Hacker, Ray Kilcoyne, J David Ingram, Michael L Manco-Johnson, Sharon Funk, Linda Jacobson,[...]. N Engl J Med 2007
15
Factor VIII inhibitors in hemophilia A: rationale and latest evidence.
Char Witmer, Guy Young. Ther Adv Hematol 2013
Char Witmer, Guy Young. Ther Adv Hematol 2013
15
Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant.
Lindsey A George, Spencer K Sullivan, Adam Giermasz, John E J Rasko, Benjamin J Samelson-Jones, Jonathan Ducore, Adam Cuker, Lisa M Sullivan, Suvankar Majumdar, Jerome Teitel,[...]. N Engl J Med 2017
Lindsey A George, Spencer K Sullivan, Adam Giermasz, John E J Rasko, Benjamin J Samelson-Jones, Jonathan Ducore, Adam Cuker, Lisa M Sullivan, Suvankar Majumdar, Jerome Teitel,[...]. N Engl J Med 2017
15
Routine measurements of factor VIII activity and inhibitor titer in the presence of emicizumab utilizing anti-idiotype monoclonal antibodies.
K Nogami, T Soeda, T Matsumoto, Y Kawabe, T Kitazawa, M Shima. J Thromb Haemost 2018
K Nogami, T Soeda, T Matsumoto, Y Kawabe, T Kitazawa, M Shima. J Thromb Haemost 2018
15
Contribution of natural anticoagulant and fibrinolytic factors in modulating the clinical severity of haemophilia patients.
Shrimati Shetty, Sonal Vora, Bipin Kulkarni, Leenam Mota, Manasi Vijapurkar, Leera Quadros, Kanjaksha Ghosh. Br J Haematol 2007
Shrimati Shetty, Sonal Vora, Bipin Kulkarni, Leenam Mota, Manasi Vijapurkar, Leera Quadros, Kanjaksha Ghosh. Br J Haematol 2007
15
The current state and future directions of RNAi-based therapeutics.
Ryan L Setten, John J Rossi, Si-Ping Han. Nat Rev Drug Discov 2019
Ryan L Setten, John J Rossi, Si-Ping Han. Nat Rev Drug Discov 2019
15
RNA-Targeted Therapeutics.
Stanley T Crooke, Joseph L Witztum, C Frank Bennett, Brenda F Baker. Cell Metab 2018
Stanley T Crooke, Joseph L Witztum, C Frank Bennett, Brenda F Baker. Cell Metab 2018
13
Concizumab, an anti-tissue factor pathway inhibitor antibody, induces increased thrombin generation in plasma from haemophilia patients and healthy subjects measured by the thrombin generation assay.
E K Waters, J Sigh, U Friedrich, I Hilden, B B Sørensen. Haemophilia 2017
E K Waters, J Sigh, U Friedrich, I Hilden, B B Sørensen. Haemophilia 2017
13
A randomized trial of safety, pharmacokinetics and pharmacodynamics of concizumab in people with hemophilia A.
H Eichler, P Angchaisuksiri, K Kavakli, P Knoebl, J Windyga, V Jiménez-Yuste, A Hyseni, U Friedrich, P Chowdary. J Thromb Haemost 2018
H Eichler, P Angchaisuksiri, K Kavakli, P Knoebl, J Windyga, V Jiménez-Yuste, A Hyseni, U Friedrich, P Chowdary. J Thromb Haemost 2018
17
A first-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of PF-06741086, an anti-tissue factor pathway inhibitor mAb, in healthy volunteers.
M Cardinal, C Kantaridis, T Zhu, P Sun, D D Pittman, J E Murphy, S Arkin. J Thromb Haemost 2018
M Cardinal, C Kantaridis, T Zhu, P Sun, D D Pittman, J E Murphy, S Arkin. J Thromb Haemost 2018
18
Mechanistic Modeling of the Pharmacodynamic and Pharmacokinetic Relationship of Tissue Factor Pathway Inhibitor-Neutralizing Antibody (BAY 1093884) in Cynomolgus Monkeys.
Jian-Ming Gu, Xiao-Yan Zhao, Thomas Schwarz, Joachim Schuhmacher, Andreas Baumann, Elena Ho, Babu Subramanyan, Kathy Tran, Timothy Myles, Chandra Patel,[...]. AAPS J 2017
Jian-Ming Gu, Xiao-Yan Zhao, Thomas Schwarz, Joachim Schuhmacher, Andreas Baumann, Elena Ho, Babu Subramanyan, Kathy Tran, Timothy Myles, Chandra Patel,[...]. AAPS J 2017
17
Factor VIII-Mimetic Function of Humanized Bispecific Antibody in Hemophilia A.
Midori Shima, Hideji Hanabusa, Masashi Taki, Tadashi Matsushita, Tetsuji Sato, Katsuyuki Fukutake, Naoki Fukazawa, Koichiro Yoneyama, Hiroki Yoshida, Keiji Nogami. N Engl J Med 2016
Midori Shima, Hideji Hanabusa, Masashi Taki, Tadashi Matsushita, Tetsuji Sato, Katsuyuki Fukutake, Naoki Fukazawa, Koichiro Yoneyama, Hiroki Yoshida, Keiji Nogami. N Engl J Med 2016
13
New therapies using nonfactor products for patients with hemophilia and inhibitors.
Keiji Nogami, Midori Shima. Blood 2019
Keiji Nogami, Midori Shima. Blood 2019
18
Long-term safety and efficacy of factor IX gene therapy in hemophilia B.
Amit C Nathwani, Ulreke M Reiss, Edward G D Tuddenham, Cecilia Rosales, Pratima Chowdary, Jenny McIntosh, Marco Della Peruta, Elsa Lheriteau, Nishal Patel, Deepak Raj,[...]. N Engl J Med 2014
Amit C Nathwani, Ulreke M Reiss, Edward G D Tuddenham, Cecilia Rosales, Pratima Chowdary, Jenny McIntosh, Marco Della Peruta, Elsa Lheriteau, Nishal Patel, Deepak Raj,[...]. N Engl J Med 2014
13
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells.
S M Elbashir, J Harborth, W Lendeckel, A Yalcin, K Weber, T Tuschl. Nature 2001
S M Elbashir, J Harborth, W Lendeckel, A Yalcin, K Weber, T Tuschl. Nature 2001
13
Anti-tissue factor pathway inhibitor (TFPI) therapy: a novel approach to the treatment of haemophilia.
Pratima Chowdary. Int J Hematol 2020
Pratima Chowdary. Int J Hematol 2020
19
Design and characterization of an APC-specific serpin for the treatment of hemophilia.
Stéphanie G I Polderdijk, Ty E Adams, Lacramioara Ivanciu, Rodney M Camire, Trevor P Baglin, James A Huntington. Blood 2017
Stéphanie G I Polderdijk, Ty E Adams, Lacramioara Ivanciu, Rodney M Camire, Trevor P Baglin, James A Huntington. Blood 2017
13
Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice.
Thazha P Prakash, Mark J Graham, Jinghua Yu, Rick Carty, Audrey Low, Alfred Chappell, Karsten Schmidt, Chenguang Zhao, Mariam Aghajan, Heather F Murray,[...]. Nucleic Acids Res 2014
Thazha P Prakash, Mark J Graham, Jinghua Yu, Rick Carty, Audrey Low, Alfred Chappell, Karsten Schmidt, Chenguang Zhao, Mariam Aghajan, Heather F Murray,[...]. Nucleic Acids Res 2014
11
Optimal treatment strategies for hemophilia: achievements and limitations of current prophylactic regimens.
Johannes Oldenburg. Blood 2015
Johannes Oldenburg. Blood 2015
11
Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.
Jerry S Powell, K John Pasi, Margaret V Ragni, Margareth C Ozelo, Leonard A Valentino, Johnny N Mahlangu, Neil C Josephson, David Perry, Marilyn J Manco-Johnson, Shashikant Apte,[...]. N Engl J Med 2013
Jerry S Powell, K John Pasi, Margaret V Ragni, Margareth C Ozelo, Leonard A Valentino, Johnny N Mahlangu, Neil C Josephson, David Perry, Marilyn J Manco-Johnson, Shashikant Apte,[...]. N Engl J Med 2013
11
Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model.
Ida Hilden, Brian Lauritzen, Brit Binow Sørensen, Jes Thorn Clausen, Christina Jespersgaard, Berit Olsen Krogh, Andrew Neil Bowler, Jens Breinholt, Albrecht Gruhler, L Anders Svensson,[...]. Blood 2012
Ida Hilden, Brian Lauritzen, Brit Binow Sørensen, Jes Thorn Clausen, Christina Jespersgaard, Berit Olsen Krogh, Andrew Neil Bowler, Jens Breinholt, Albrecht Gruhler, L Anders Svensson,[...]. Blood 2012
11
Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors.
Sylvie Boutin, Virginie Monteilhet, Philippe Veron, Christian Leborgne, Olivier Benveniste, Marie Françoise Montus, Carole Masurier. Hum Gene Ther 2010
Sylvie Boutin, Virginie Monteilhet, Philippe Veron, Christian Leborgne, Olivier Benveniste, Marie Françoise Montus, Carole Masurier. Hum Gene Ther 2010
11
In vitro studies show synergistic effects of a procoagulant bispecific antibody and bypassing agents.
R Hartmann, T Feenstra, L Valentino, M Dockal, F Scheiflinger. J Thromb Haemost 2018
R Hartmann, T Feenstra, L Valentino, M Dockal, F Scheiflinger. J Thromb Haemost 2018
11
Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A.
Johnny Mahlangu, Jerry S Powell, Margaret V Ragni, Pratima Chowdary, Neil C Josephson, Ingrid Pabinger, Hideji Hanabusa, Naresh Gupta, Roshni Kulkarni, Patrick Fogarty,[...]. Blood 2014
Johnny Mahlangu, Jerry S Powell, Margaret V Ragni, Pratima Chowdary, Neil C Josephson, Ingrid Pabinger, Hideji Hanabusa, Naresh Gupta, Roshni Kulkarni, Patrick Fogarty,[...]. Blood 2014
11
Gene therapy with adeno-associated virus vector 5-human factor IX in adults with hemophilia B.
Wolfgang Miesbach, Karina Meijer, Michiel Coppens, Peter Kampmann, Robert Klamroth, Roger Schutgens, Marco Tangelder, Giancarlo Castaman, Joachim Schwäble, Halvard Bonig,[...]. Blood 2018
Wolfgang Miesbach, Karina Meijer, Michiel Coppens, Peter Kampmann, Robert Klamroth, Roger Schutgens, Marco Tangelder, Giancarlo Castaman, Joachim Schwäble, Halvard Bonig,[...]. Blood 2018
11
Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates.
Jayaprakash K Nair, Husain Attarwala, Alfica Sehgal, Qianfan Wang, Krishna Aluri, Xuemei Zhang, Minggeng Gao, Ju Liu, Ramesh Indrakanti, Sally Schofield,[...]. Nucleic Acids Res 2017
Jayaprakash K Nair, Husain Attarwala, Alfica Sehgal, Qianfan Wang, Krishna Aluri, Xuemei Zhang, Minggeng Gao, Ju Liu, Ramesh Indrakanti, Sally Schofield,[...]. Nucleic Acids Res 2017
11
Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria.
Eliane Sardh, Pauline Harper, Manisha Balwani, Penelope Stein, David Rees, D Montgomery Bissell, Robert Desnick, Charles Parker, John Phillips, Herbert L Bonkovsky,[...]. N Engl J Med 2019
Eliane Sardh, Pauline Harper, Manisha Balwani, Penelope Stein, David Rees, D Montgomery Bissell, Robert Desnick, Charles Parker, John Phillips, Herbert L Bonkovsky,[...]. N Engl J Med 2019
11
Targeting activated protein C to treat hemophilia.
Stéphanie G I Polderdijk, Trevor P Baglin, James A Huntington. Curr Opin Hematol 2017
Stéphanie G I Polderdijk, Trevor P Baglin, James A Huntington. Curr Opin Hematol 2017
20
Single-domain antibodies targeting antithrombin reduce bleeding in hemophilic mice with or without inhibitors.
Elena Barbon, Gabriel Ayme, Amel Mohamadi, Jean-François Ottavi, Charlotte Kawecki, Caterina Casari, Sebastien Verhenne, Solenne Marmier, Laetitia van Wittenberghe, Severine Charles,[...]. EMBO Mol Med 2020
Elena Barbon, Gabriel Ayme, Amel Mohamadi, Jean-François Ottavi, Charlotte Kawecki, Caterina Casari, Sebastien Verhenne, Solenne Marmier, Laetitia van Wittenberghe, Severine Charles,[...]. EMBO Mol Med 2020
38
A multicenter, open-label phase 3 study of emicizumab prophylaxis in children with hemophilia A with inhibitors.
Guy Young, Ri Liesner, Tiffany Chang, Robert Sidonio, Johannes Oldenburg, Victor Jiménez-Yuste, Johnny Mahlangu, Rebecca Kruse-Jarres, Michael Wang, Marianne Uguen,[...]. Blood 2019
Guy Young, Ri Liesner, Tiffany Chang, Robert Sidonio, Johannes Oldenburg, Victor Jiménez-Yuste, Johnny Mahlangu, Rebecca Kruse-Jarres, Michael Wang, Marianne Uguen,[...]. Blood 2019
11
Treatment of bleeding episodes in haemophilia A complicated by a factor VIII inhibitor in patients receiving Emicizumab. Interim guidance from UKHCDO Inhibitor Working Party and Executive Committee.
P W Collins, R Liesner, M Makris, K Talks, P Chowdary, E Chalmers, G Hall, A Riddell, C L Percy, C R Hay,[...]. Haemophilia 2018
P W Collins, R Liesner, M Makris, K Talks, P Chowdary, E Chalmers, G Hall, A Riddell, C L Percy, C R Hay,[...]. Haemophilia 2018
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.