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Times Cited
Times Co-cited
Similarity
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The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.
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Maximiliano A D'Angelo, Marcela Raices, Siler H Panowski, Martin W Hetzer. Cell 2009
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Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport.
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Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.
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GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.
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TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
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Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia.
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Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.
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Stress Granule Assembly Disrupts Nucleocytoplasmic Transport.
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The nuclear pore complex: understanding its function through structural insight.
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Simple rules for passive diffusion through the nuclear pore complex.
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Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
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Nuclear pore complex proteins in Alzheimer disease.
Lynette G Sheffield, Hayley B Miskiewicz, Lindsey B Tannenbaum, Suzanne S Mirra. J Neuropathol Exp Neurol 2006
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Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD.
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C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins.
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Tau-induced nuclear envelope invagination causes a toxic accumulation of mRNA in Drosophila.
Garrett L Cornelison, Simon A Levy, Tyler Jenson, Bess Frost. Aging Cell 2019
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A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes.
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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
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12
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.
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Nucleocytoplasmic transport defects in neurodegeneration - Cause or consequence?
Saskia Hutten, Dorothee Dormann. Semin Cell Dev Biol 2020
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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
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12
Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export.
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11
Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells.
Brandon H Toyama, Rafael Arrojo E Drigo, Varda Lev-Ram, Ranjan Ramachandra, Thomas J Deerinck, Claude Lechene, Mark H Ellisman, Martin W Hetzer. J Cell Biol 2019
Brandon H Toyama, Rafael Arrojo E Drigo, Varda Lev-Ram, Ranjan Ramachandra, Thomas J Deerinck, Claude Lechene, Mark H Ellisman, Martin W Hetzer. J Cell Biol 2019
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Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death.
Fatima Gasset-Rosa, Shan Lu, Haiyang Yu, Cong Chen, Ze'ev Melamed, Lin Guo, James Shorter, Sandrine Da Cruz, Don W Cleveland. Neuron 2019
Fatima Gasset-Rosa, Shan Lu, Haiyang Yu, Cong Chen, Ze'ev Melamed, Lin Guo, James Shorter, Sandrine Da Cruz, Don W Cleveland. Neuron 2019
11
Tau protein liquid-liquid phase separation can initiate tau aggregation.
Susanne Wegmann, Bahareh Eftekharzadeh, Katharina Tepper, Katarzyna M Zoltowska, Rachel E Bennett, Simon Dujardin, Pawel R Laskowski, Danny MacKenzie, Tarun Kamath, Caitlin Commins,[...]. EMBO J 2018
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11
Extremely long-lived nuclear pore proteins in the rat brain.
Jeffrey N Savas, Brandon H Toyama, Tao Xu, John R Yates, Martin W Hetzer. Science 2012
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10
Post-translational O-GlcNAcylation is essential for nuclear pore integrity and maintenance of the pore selectivity filter.
Yanping Zhu, Ta-Wei Liu, Zarina Madden, Scott A Yuzwa, Kelsey Murray, Samy Cecioni, Natasha Zachara, David J Vocadlo. J Mol Cell Biol 2016
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Integrative structure and functional anatomy of a nuclear pore complex.
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FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties.
Steffen Frey, Ralf P Richter, Dirk Görlich. Science 2006
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Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles.
H Broder Schmidt, Dirk Görlich. Trends Biochem Sci 2016
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Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
Bahram Khosravi, Hannelore Hartmann, Stephanie May, Christoph Möhl, Helena Ederle, Meike Michaelsen, Martin H Schludi, Dorothee Dormann, Dieter Edbauer. Hum Mol Genet 2017
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Structure and Assembly of the Nuclear Pore Complex.
Bernhard Hampoelz, Amparo Andres-Pons, Panagiotis Kastritis, Martin Beck. Annu Rev Biophys 2019
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RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
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The Structure of the Nuclear Pore Complex (An Update).
Daniel H Lin, André Hoelz. Annu Rev Biochem 2019
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Nuclear tau, a key player in neuronal DNA protection.
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Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.
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The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
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The nuclear pore complex and nuclear transport.
Susan R Wente, Michael P Rout. Cold Spring Harb Perspect Biol 2010
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TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia.
Hilary C Archbold, Kasey L Jackson, Ayush Arora, Kaitlin Weskamp, Elizabeth M-H Tank, Xingli Li, Roberto Miguez, Robert D Dayton, Sharon Tamir, Ronald L Klein,[...]. Sci Rep 2018
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Nuclear contour irregularity and abnormal transporter protein distribution in anterior horn cells in amyotrophic lateral sclerosis.
Yoshimi Kinoshita, Hidefumi Ito, Asao Hirano, Kengo Fujita, Reika Wate, Masataka Nakamura, Satoshi Kaneko, Satoshi Nakano, Hirofumi Kusaka. J Neuropathol Exp Neurol 2009
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Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1.
Helena Ederle, Christina Funk, Claudia Abou-Ajram, Saskia Hutten, Eva B E Funk, Ralph H Kehlenbach, Susanne M Bailer, Dorothee Dormann. Sci Rep 2018
Helena Ederle, Christina Funk, Claudia Abou-Ajram, Saskia Hutten, Eva B E Funk, Ralph H Kehlenbach, Susanne M Bailer, Dorothee Dormann. Sci Rep 2018
13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.