Se Hoon Choi, Enjana Bylykbashi, Zena K Chatila, Star W Lee, Benjamin Pulli, Gregory D Clemenson, Eunhee Kim, Alexander Rompala, Mary K Oram, Caroline Asselin, Jenna Aronson, Can Zhang, Sean J Miller, Andrea Lesinski, John W Chen, Doo Yeon Kim, Henriette van Praag, Bruce M Spiegelman, Fred H Gage, Rudolph E Tanzi. Science 2018
Times Cited: 273
Times Cited: 273
Times Cited
Times Co-cited
Similarity
Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease.
Elena P Moreno-Jiménez, Miguel Flor-García, Julia Terreros-Roncal, Alberto Rábano, Fabio Cafini, Noemí Pallas-Bazarra, Jesús Ávila, María Llorens-Martín. Nat Med 2019
Elena P Moreno-Jiménez, Miguel Flor-García, Julia Terreros-Roncal, Alberto Rábano, Fabio Cafini, Noemí Pallas-Bazarra, Jesús Ávila, María Llorens-Martín. Nat Med 2019
31
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.
Mychael V Lourenco, Rudimar L Frozza, Guilherme B de Freitas, Hong Zhang, Grasielle C Kincheski, Felipe C Ribeiro, Rafaella A Gonçalves, Julia R Clarke, Danielle Beckman, Agnieszka Staniszewski,[...]. Nat Med 2019
Mychael V Lourenco, Rudimar L Frozza, Guilherme B de Freitas, Hong Zhang, Grasielle C Kincheski, Felipe C Ribeiro, Rafaella A Gonçalves, Julia R Clarke, Danielle Beckman, Agnieszka Staniszewski,[...]. Nat Med 2019
22
Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway.
Christiane D Wrann, James P White, John Salogiannnis, Dina Laznik-Bogoslavski, Jun Wu, Di Ma, Jiandie D Lin, Michael E Greenberg, Bruce M Spiegelman. Cell Metab 2013
Christiane D Wrann, James P White, John Salogiannnis, Dina Laznik-Bogoslavski, Jun Wu, Di Ma, Jiandie D Lin, Michael E Greenberg, Bruce M Spiegelman. Cell Metab 2013
20
Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients.
Matthew K Tobin, Kianna Musaraca, Ahmed Disouky, Aashutosh Shetti, Abdullah Bheri, William G Honer, Namhee Kim, Robert J Dawe, David A Bennett, Konstantinos Arfanakis,[...]. Cell Stem Cell 2019
Matthew K Tobin, Kianna Musaraca, Ahmed Disouky, Aashutosh Shetti, Abdullah Bheri, William G Honer, Namhee Kim, Robert J Dawe, David A Bennett, Konstantinos Arfanakis,[...]. Cell Stem Cell 2019
19
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus.
H van Praag, G Kempermann, F H Gage. Nat Neurosci 1999
H van Praag, G Kempermann, F H Gage. Nat Neurosci 1999
16
Neurogenesis in the adult human hippocampus.
P S Eriksson, E Perfilieva, T Björk-Eriksson, A M Alborn, C Nordborg, D A Peterson, F H Gage. Nat Med 1998
P S Eriksson, E Perfilieva, T Björk-Eriksson, A M Alborn, C Nordborg, D A Peterson, F H Gage. Nat Med 1998
15
Human Hippocampal Neurogenesis Persists throughout Aging.
Maura Boldrini, Camille A Fulmore, Alexandria N Tartt, Laika R Simeon, Ina Pavlova, Verica Poposka, Gorazd B Rosoklija, Aleksandar Stankov, Victoria Arango, Andrew J Dwork,[...]. Cell Stem Cell 2018
Maura Boldrini, Camille A Fulmore, Alexandria N Tartt, Laika R Simeon, Ina Pavlova, Verica Poposka, Gorazd B Rosoklija, Aleksandar Stankov, Victoria Arango, Andrew J Dwork,[...]. Cell Stem Cell 2018
14
Exercise enhances learning and hippocampal neurogenesis in aged mice.
Henriette van Praag, Tiffany Shubert, Chunmei Zhao, Fred H Gage. J Neurosci 2005
Henriette van Praag, Tiffany Shubert, Chunmei Zhao, Fred H Gage. J Neurosci 2005
13
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Pontus Boström, Jun Wu, Mark P Jedrychowski, Anisha Korde, Li Ye, James C Lo, Kyle A Rasbach, Elisabeth Almer Boström, Jang Hyun Choi, Jonathan Z Long,[...]. Nature 2012
Pontus Boström, Jun Wu, Mark P Jedrychowski, Anisha Korde, Li Ye, James C Lo, Kyle A Rasbach, Elisabeth Almer Boström, Jang Hyun Choi, Jonathan Z Long,[...]. Nature 2012
13
Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition.
Shoshanna Vaynman, Zhe Ying, Fernando Gomez-Pinilla. Eur J Neurosci 2004
Shoshanna Vaynman, Zhe Ying, Fernando Gomez-Pinilla. Eur J Neurosci 2004
13
Dynamics of hippocampal neurogenesis in adult humans.
Kirsty L Spalding, Olaf Bergmann, Kanar Alkass, Samuel Bernard, Mehran Salehpour, Hagen B Huttner, Emil Boström, Isabelle Westerlund, Celine Vial, Bruce A Buchholz,[...]. Cell 2013
Kirsty L Spalding, Olaf Bergmann, Kanar Alkass, Samuel Bernard, Mehran Salehpour, Hagen B Huttner, Emil Boström, Isabelle Westerlund, Celine Vial, Bruce A Buchholz,[...]. Cell 2013
12
Human Adult Neurogenesis: Evidence and Remaining Questions.
Gerd Kempermann, Fred H Gage, Ludwig Aigner, Hongjun Song, Maurice A Curtis, Sandrine Thuret, H Georg Kuhn, Sebastian Jessberger, Paul W Frankland, Heather A Cameron,[...]. Cell Stem Cell 2018
Gerd Kempermann, Fred H Gage, Ludwig Aigner, Hongjun Song, Maurice A Curtis, Sandrine Thuret, H Georg Kuhn, Sebastian Jessberger, Paul W Frankland, Heather A Cameron,[...]. Cell Stem Cell 2018
12
Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-Dependent Activation of Hippocampal Brain-Derived Neurotrophic Factor (BDNF).
Lauretta El Hayek, Mohamad Khalifeh, Victor Zibara, Rawad Abi Assaad, Nancy Emmanuel, Nabil Karnib, Rim El-Ghandour, Patrick Nasrallah, Maria Bilen, Pascale Ibrahim,[...]. J Neurosci 2019
Lauretta El Hayek, Mohamad Khalifeh, Victor Zibara, Rawad Abi Assaad, Nancy Emmanuel, Nabil Karnib, Rim El-Ghandour, Patrick Nasrallah, Maria Bilen, Pascale Ibrahim,[...]. J Neurosci 2019
11
Exercise training increases size of hippocampus and improves memory.
Kirk I Erickson, Michelle W Voss, Ruchika Shaurya Prakash, Chandramallika Basak, Amanda Szabo, Laura Chaddock, Jennifer S Kim, Susie Heo, Heloisa Alves, Siobhan M White,[...]. Proc Natl Acad Sci U S A 2011
Kirk I Erickson, Michelle W Voss, Ruchika Shaurya Prakash, Chandramallika Basak, Amanda Szabo, Laura Chaddock, Jennifer S Kim, Susie Heo, Heloisa Alves, Siobhan M White,[...]. Proc Natl Acad Sci U S A 2011
10
Adult hippocampal neurogenesis and cognitive flexibility - linking memory and mood.
Christoph Anacker, René Hen. Nat Rev Neurosci 2017
Christoph Anacker, René Hen. Nat Rev Neurosci 2017
10
Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function.
Hyo Youl Moon, Andreas Becke, David Berron, Benjamin Becker, Nirnath Sah, Galit Benoni, Emma Janke, Susan T Lubejko, Nigel H Greig, Julie A Mattison,[...]. Cell Metab 2016
Hyo Youl Moon, Andreas Becke, David Berron, Benjamin Becker, Nirnath Sah, Galit Benoni, Emma Janke, Susan T Lubejko, Nigel H Greig, Julie A Mattison,[...]. Cell Metab 2016
10
Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation.
Amar Sahay, Kimberly N Scobie, Alexis S Hill, Colin M O'Carroll, Mazen A Kheirbek, Nesha S Burghardt, André A Fenton, Alex Dranovsky, René Hen. Nature 2011
Amar Sahay, Kimberly N Scobie, Alexis S Hill, Colin M O'Carroll, Mazen A Kheirbek, Nesha S Burghardt, André A Fenton, Alex Dranovsky, René Hen. Nature 2011
10
Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain.
Alana M Horowitz, Xuelai Fan, Gregor Bieri, Lucas K Smith, Cesar I Sanchez-Diaz, Adam B Schroer, Geraldine Gontier, Kaitlin B Casaletto, Joel H Kramer, Katherine E Williams,[...]. Science 2020
Alana M Horowitz, Xuelai Fan, Gregor Bieri, Lucas K Smith, Cesar I Sanchez-Diaz, Adam B Schroer, Geraldine Gontier, Kaitlin B Casaletto, Joel H Kramer, Katherine E Williams,[...]. Science 2020
13
Neuroinflammation in Alzheimer's disease.
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
9
A functional role for adult hippocampal neurogenesis in spatial pattern separation.
C D Clelland, M Choi, C Romberg, G D Clemenson, A Fragniere, P Tyers, S Jessberger, L M Saksida, R A Barker, F H Gage,[...]. Science 2009
C D Clelland, M Choi, C Romberg, G D Clemenson, A Fragniere, P Tyers, S Jessberger, L M Saksida, R A Barker, F H Gage,[...]. Science 2009
9
Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults.
Shawn F Sorrells, Mercedes F Paredes, Arantxa Cebrian-Silla, Kadellyn Sandoval, Dashi Qi, Kevin W Kelley, David James, Simone Mayer, Julia Chang, Kurtis I Auguste,[...]. Nature 2018
Shawn F Sorrells, Mercedes F Paredes, Arantxa Cebrian-Silla, Kadellyn Sandoval, Dashi Qi, Kevin W Kelley, David James, Simone Mayer, Julia Chang, Kurtis I Auguste,[...]. Nature 2018
9
Neurotrophin regulation of neural circuit development and function.
Hyungju Park, Mu-ming Poo. Nat Rev Neurosci 2013
Hyungju Park, Mu-ming Poo. Nat Rev Neurosci 2013
8
Exercise-Mediated Neurogenesis in the Hippocampus via BDNF.
Patrick Z Liu, Robin Nusslock. Front Neurosci 2018
Patrick Z Liu, Robin Nusslock. Front Neurosci 2018
8
8
Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging.
J Eric Ahlskog, Yonas E Geda, Neill R Graff-Radford, Ronald C Petersen. Mayo Clin Proc 2011
J Eric Ahlskog, Yonas E Geda, Neill R Graff-Radford, Ronald C Petersen. Mayo Clin Proc 2011
8
Functional neurogenesis in the adult hippocampus.
Henriette van Praag, Alejandro F Schinder, Brian R Christie, Nicolas Toni, Theo D Palmer, Fred H Gage. Nature 2002
Henriette van Praag, Alejandro F Schinder, Brian R Christie, Nicolas Toni, Theo D Palmer, Fred H Gage. Nature 2002
7
More hippocampal neurons in adult mice living in an enriched environment.
G Kempermann, H G Kuhn, F H Gage. Nature 1997
G Kempermann, H G Kuhn, F H Gage. Nature 1997
7
Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.
Shiyong Peng, Joanne Wuu, Elliott J Mufson, Margaret Fahnestock. J Neurochem 2005
Shiyong Peng, Joanne Wuu, Elliott J Mufson, Margaret Fahnestock. J Neurochem 2005
7
Decreased Serum Brain-Derived Neurotrophic Factor (BDNF) Levels in Patients with Alzheimer's Disease (AD): A Systematic Review and Meta-Analysis.
Ted Kheng Siang Ng, Cyrus Su Hui Ho, Wilson Wai San Tam, Ee Heok Kua, Roger Chun-Man Ho. Int J Mol Sci 2019
Ted Kheng Siang Ng, Cyrus Su Hui Ho, Wilson Wai San Tam, Ee Heok Kua, Roger Chun-Man Ho. Int J Mol Sci 2019
7
The ageing systemic milieu negatively regulates neurogenesis and cognitive function.
Saul A Villeda, Jian Luo, Kira I Mosher, Bende Zou, Markus Britschgi, Gregor Bieri, Trisha M Stan, Nina Fainberg, Zhaoqing Ding, Alexander Eggel,[...]. Nature 2011
Saul A Villeda, Jian Luo, Kira I Mosher, Bende Zou, Markus Britschgi, Gregor Bieri, Trisha M Stan, Nina Fainberg, Zhaoqing Ding, Alexander Eggel,[...]. Nature 2011
7
Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer's disease by compromising hippocampal inhibition.
Carolyn Hollands, Matthew Kyle Tobin, Michael Hsu, Kianna Musaraca, Tzong-Shiue Yu, Rachana Mishra, Steven G Kernie, Orly Lazarov. Mol Neurodegener 2017
Carolyn Hollands, Matthew Kyle Tobin, Michael Hsu, Kianna Musaraca, Tzong-Shiue Yu, Rachana Mishra, Steven G Kernie, Orly Lazarov. Mol Neurodegener 2017
11
The role of adult hippocampal neurogenesis in brain health and disease.
Tomohisa Toda, Sarah L Parylak, Sara B Linker, Fred H Gage. Mol Psychiatry 2019
Tomohisa Toda, Sarah L Parylak, Sara B Linker, Fred H Gage. Mol Psychiatry 2019
7
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.
Holly Oakley, Sarah L Cole, Sreemathi Logan, Erika Maus, Pei Shao, Jeffery Craft, Angela Guillozet-Bongaarts, Masuo Ohno, John Disterhoft, Linda Van Eldik,[...]. J Neurosci 2006
Holly Oakley, Sarah L Cole, Sreemathi Logan, Erika Maus, Pei Shao, Jeffery Craft, Angela Guillozet-Bongaarts, Masuo Ohno, John Disterhoft, Linda Van Eldik,[...]. J Neurosci 2006
7
Adult hippocampal neurogenesis and its role in Alzheimer's disease.
Yangling Mu, Fred H Gage. Mol Neurodegener 2011
Yangling Mu, Fred H Gage. Mol Neurodegener 2011
7
Running enhances neurogenesis, learning, and long-term potentiation in mice.
H van Praag, B R Christie, T J Sejnowski, F H Gage. Proc Natl Acad Sci U S A 1999
H van Praag, B R Christie, T J Sejnowski, F H Gage. Proc Natl Acad Sci U S A 1999
7
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.
Saul A Villeda, Kristopher E Plambeck, Jinte Middeldorp, Joseph M Castellano, Kira I Mosher, Jian Luo, Lucas K Smith, Gregor Bieri, Karin Lin, Daniela Berdnik,[...]. Nat Med 2014
Saul A Villeda, Kristopher E Plambeck, Jinte Middeldorp, Joseph M Castellano, Kira I Mosher, Jian Luo, Lucas K Smith, Gregor Bieri, Karin Lin, Daniela Berdnik,[...]. Nat Med 2014
7
An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus.
Ana C Pereira, Dan E Huddleston, Adam M Brickman, Alexander A Sosunov, Rene Hen, Guy M McKhann, Richard Sloan, Fred H Gage, Truman R Brown, Scott A Small. Proc Natl Acad Sci U S A 2007
Ana C Pereira, Dan E Huddleston, Adam M Brickman, Alexander A Sosunov, Rene Hen, Guy M McKhann, Richard Sloan, Fred H Gage, Truman R Brown, Scott A Small. Proc Natl Acad Sci U S A 2007
7
Lactate infusion at rest increases BDNF blood concentration in humans.
Thorsten Schiffer, Stefanie Schulte, Billy Sperlich, Silvia Achtzehn, Hannes Fricke, Heiko K Strüder. Neurosci Lett 2011
Thorsten Schiffer, Stefanie Schulte, Billy Sperlich, Silvia Achtzehn, Hannes Fricke, Heiko K Strüder. Neurosci Lett 2011
10
Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus.
Chunmei Zhao, E Matthew Teng, Robert G Summers, Guo-Li Ming, Fred H Gage. J Neurosci 2006
Chunmei Zhao, E Matthew Teng, Robert G Summers, Guo-Li Ming, Fred H Gage. J Neurosci 2006
6
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease.
Alan H Nagahara, David A Merrill, Giovanni Coppola, Shingo Tsukada, Brock E Schroeder, Gideon M Shaked, Ling Wang, Armin Blesch, Albert Kim, James M Conner,[...]. Nat Med 2009
Alan H Nagahara, David A Merrill, Giovanni Coppola, Shingo Tsukada, Brock E Schroeder, Gideon M Shaked, Ling Wang, Armin Blesch, Albert Kim, James M Conner,[...]. Nat Med 2009
6
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.
Mathew Blurton-Jones, Masashi Kitazawa, Hilda Martinez-Coria, Nicholas A Castello, Franz-Josef Müller, Jeanne F Loring, Tritia R Yamasaki, Wayne W Poon, Kim N Green, Frank M LaFerla. Proc Natl Acad Sci U S A 2009
Mathew Blurton-Jones, Masashi Kitazawa, Hilda Martinez-Coria, Nicholas A Castello, Franz-Josef Müller, Jeanne F Loring, Tritia R Yamasaki, Wayne W Poon, Kim N Green, Frank M LaFerla. Proc Natl Acad Sci U S A 2009
6
Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats.
S Arancibia, M Silhol, F Moulière, J Meffre, I Höllinger, T Maurice, L Tapia-Arancibia. Neurobiol Dis 2008
S Arancibia, M Silhol, F Moulière, J Meffre, I Höllinger, T Maurice, L Tapia-Arancibia. Neurobiol Dis 2008
6
Exercise and BDNF reduce Aβ production by enhancing α-secretase processing of APP.
Saket M Nigam, Shaohua Xu, Joanna S Kritikou, Krisztina Marosi, Lennart Brodin, Mark P Mattson. J Neurochem 2017
Saket M Nigam, Shaohua Xu, Joanna S Kritikou, Krisztina Marosi, Lennart Brodin, Mark P Mattson. J Neurochem 2017
8
The yin and yang of neurotrophin action.
Bai Lu, Petti T Pang, Newton H Woo. Nat Rev Neurosci 2005
Bai Lu, Petti T Pang, Newton H Woo. Nat Rev Neurosci 2005
6
The amyloid hypothesis of Alzheimer's disease at 25 years.
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
6
Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate.
Sama F Sleiman, Jeffrey Henry, Rami Al-Haddad, Lauretta El Hayek, Edwina Abou Haidar, Thomas Stringer, Devyani Ulja, Saravanan S Karuppagounder, Edward B Holson, Rajiv R Ratan,[...]. Elife 2016
Sama F Sleiman, Jeffrey Henry, Rami Al-Haddad, Lauretta El Hayek, Edwina Abou Haidar, Thomas Stringer, Devyani Ulja, Saravanan S Karuppagounder, Edward B Holson, Rajiv R Ratan,[...]. Elife 2016
6
Adult neurogenesis, human after all (again): Classic, optimized, and future approaches.
Paul J Lucassen, Carlos P Fitzsimons, Evgenia Salta, Mirjana Maletic-Savatic. Behav Brain Res 2020
Paul J Lucassen, Carlos P Fitzsimons, Evgenia Salta, Mirjana Maletic-Savatic. Behav Brain Res 2020
15
Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease.
Binggui Sun, Brian Halabisky, Yungui Zhou, Jorge J Palop, Guiqiu Yu, Lennart Mucke, Li Gan. Cell Stem Cell 2009
Binggui Sun, Brian Halabisky, Yungui Zhou, Jorge J Palop, Guiqiu Yu, Lennart Mucke, Li Gan. Cell Stem Cell 2009
6
Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.
Yujiao Lu, Yan Dong, Donovan Tucker, Ruimin Wang, Mohammad Ejaz Ahmed, Darrell Brann, Quanguang Zhang. J Alzheimers Dis 2017
Yujiao Lu, Yan Dong, Donovan Tucker, Ruimin Wang, Mohammad Ejaz Ahmed, Darrell Brann, Quanguang Zhang. J Alzheimers Dis 2017
6
Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease.
Benoit de Pins, Carmen Cifuentes-Díaz, Amel Thamila Farah, Laura López-Molina, Enrica Montalban, Anna Sancho-Balsells, Ana López, Silvia Ginés, José María Delgado-García, Jordi Alberch,[...]. J Neurosci 2019
Benoit de Pins, Carmen Cifuentes-Díaz, Amel Thamila Farah, Laura López-Molina, Enrica Montalban, Anna Sancho-Balsells, Ana López, Silvia Ginés, José María Delgado-García, Jordi Alberch,[...]. J Neurosci 2019
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.