Yihe Huang, Paige A Winkler, Weinan Sun, Wei Lü, Juan Du. Nature 2018
Times Cited: 93
Times Cited: 93
Times Cited
Times Co-cited
Similarity
Structures and gating mechanism of human TRPM2.
Longfei Wang, Tian-Min Fu, Yiming Zhou, Shiyu Xia, Anna Greka, Hao Wu. Science 2018
Longfei Wang, Tian-Min Fu, Yiming Zhou, Shiyu Xia, Anna Greka, Hao Wu. Science 2018
71
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation.
Zhe Zhang, Balázs Tóth, Andras Szollosi, Jue Chen, László Csanády. Elife 2018
Zhe Zhang, Balázs Tóth, Andras Szollosi, Jue Chen, László Csanády. Elife 2018
62
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.
A L Perraud, A Fleig, C A Dunn, L A Bagley, P Launay, C Schmitz, A J Stokes, Q Zhu, M J Bessman, R Penner,[...]. Nature 2001
A L Perraud, A Fleig, C A Dunn, L A Bagley, P Launay, C Schmitz, A J Stokes, Q Zhu, M J Bessman, R Penner,[...]. Nature 2001
43
Structure of the human TRPM4 ion channel in a lipid nanodisc.
Henriette E Autzen, Alexander G Myasnikov, Melody G Campbell, Daniel Asarnow, David Julius, Yifan Cheng. Science 2018
Henriette E Autzen, Alexander G Myasnikov, Melody G Campbell, Daniel Asarnow, David Julius, Yifan Cheng. Science 2018
38
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Ying Yin, Son C Le, Allen L Hsu, Mario J Borgnia, Huanghe Yang, Seok-Yong Lee. Science 2019
Ying Yin, Son C Le, Allen L Hsu, Mario J Borgnia, Huanghe Yang, Seok-Yong Lee. Science 2019
30
Structures of the calcium-activated, non-selective cation channel TRPM4.
Jiangtao Guo, Ji She, Weizhong Zeng, Qingfeng Chen, Xiao-Chen Bai, Youxing Jiang. Nature 2017
Jiangtao Guo, Ji She, Weizhong Zeng, Qingfeng Chen, Xiao-Chen Bai, Youxing Jiang. Nature 2017
29
Structure of the cold- and menthol-sensing ion channel TRPM8.
Ying Yin, Mengyu Wu, Lejla Zubcevic, William F Borschel, Gabriel C Lander, Seok-Yong Lee. Science 2018
Ying Yin, Mengyu Wu, Lejla Zubcevic, William F Borschel, Gabriel C Lander, Seok-Yong Lee. Science 2018
27
Electron cryo-microscopy structure of a human TRPM4 channel.
Paige A Winkler, Yihe Huang, Weinan Sun, Juan Du, Wei Lü. Nature 2017
Paige A Winkler, Yihe Huang, Weinan Sun, Juan Du, Wei Lü. Nature 2017
28
Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel.
Yihe Huang, Becca Roth, Wei Lü, Juan Du. Elife 2019
Yihe Huang, Becca Roth, Wei Lü, Juan Du. Elife 2019
69
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death.
Yuji Hara, Minoru Wakamori, Masakazu Ishii, Emi Maeno, Motohiro Nishida, Takashi Yoshida, Hisanobu Yamada, Shunichi Shimizu, Emiko Mori, Jun Kudoh,[...]. Mol Cell 2002
Yuji Hara, Minoru Wakamori, Masakazu Ishii, Emi Maeno, Motohiro Nishida, Takashi Yoshida, Hisanobu Yamada, Shunichi Shimizu, Emiko Mori, Jun Kudoh,[...]. Mol Cell 2002
25
TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration.
Shinichiro Yamamoto, Shunichi Shimizu, Shigeki Kiyonaka, Nobuaki Takahashi, Teruaki Wajima, Yuji Hara, Takaharu Negoro, Toshihito Hiroi, Yuji Kiuchi, Takaharu Okada,[...]. Nat Med 2008
Shinichiro Yamamoto, Shunichi Shimizu, Shigeki Kiyonaka, Nobuaki Takahashi, Teruaki Wajima, Yuji Hara, Takaharu Negoro, Toshihito Hiroi, Yuji Kiuchi, Takaharu Okada,[...]. Nat Med 2008
24
2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist.
Ralf Fliegert, Andreas Bauche, Adriana-Michelle Wolf Pérez, Joanna M Watt, Monika D Rozewitz, Riekje Winzer, Mareike Janus, Feng Gu, Annette Rosche, Angelika Harneit,[...]. Nat Chem Biol 2017
Ralf Fliegert, Andreas Bauche, Adriana-Michelle Wolf Pérez, Joanna M Watt, Monika D Rozewitz, Riekje Winzer, Mareike Janus, Feng Gu, Annette Rosche, Angelika Harneit,[...]. Nat Chem Biol 2017
42
The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity.
Iordan Iordanov, Csaba Mihályi, Balázs Tóth, László Csanády. Elife 2016
Iordan Iordanov, Csaba Mihályi, Balázs Tóth, László Csanády. Elife 2016
58
TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion.
Kazuya Togashi, Yuji Hara, Tomoko Tominaga, Tomohiro Higashi, Yasunobu Konishi, Yasuo Mori, Makoto Tominaga. EMBO J 2006
Kazuya Togashi, Yuji Hara, Tomoko Tominaga, Tomohiro Higashi, Yasunobu Konishi, Yasuo Mori, Makoto Tominaga. EMBO J 2006
21
Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels.
Anne-Laure Perraud, Christina L Takanishi, Betty Shen, Shin Kang, Megan K Smith, Carsten Schmitz, Heather M Knowles, Dana Ferraris, Weixing Li, Jie Zhang,[...]. J Biol Chem 2005
Anne-Laure Perraud, Christina L Takanishi, Betty Shen, Shin Kang, Megan K Smith, Carsten Schmitz, Heather M Knowles, Dana Ferraris, Weixing Li, Jie Zhang,[...]. J Biol Chem 2005
20
The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia.
Kun Song, Hong Wang, Gretel B Kamm, Jörg Pohle, Fernanda de Castro Reis, Paul Heppenstall, Hagen Wende, Jan Siemens. Science 2016
Kun Song, Hong Wang, Gretel B Kamm, Jörg Pohle, Fernanda de Castro Reis, Paul Heppenstall, Hagen Wende, Jan Siemens. Science 2016
19
Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
19
ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain.
Frank J P Kühn, Cornelia Kühn, Mathis Winking, Daniel C Hoffmann, Andreas Lückhoff. PLoS One 2016
Frank J P Kühn, Cornelia Kühn, Mathis Winking, Daniel C Hoffmann, Andreas Lückhoff. PLoS One 2016
77
Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Jingjing Duan, Zongli Li, Jian Li, Raymond E Hulse, Ana Santa-Cruz, William C Valinsky, Sunday A Abiria, Grigory Krapivinsky, Jin Zhang, David E Clapham. Proc Natl Acad Sci U S A 2018
Jingjing Duan, Zongli Li, Jian Li, Raymond E Hulse, Ana Santa-Cruz, William C Valinsky, Sunday A Abiria, Grigory Krapivinsky, Jin Zhang, David E Clapham. Proc Natl Acad Sci U S A 2018
28
Structure of full-length human TRPM4.
Jingjing Duan, Zongli Li, Jian Li, Ana Santa-Cruz, Silvia Sanchez-Martinez, Jin Zhang, David E Clapham. Proc Natl Acad Sci U S A 2018
Jingjing Duan, Zongli Li, Jian Li, Ana Santa-Cruz, Silvia Sanchez-Martinez, Jin Zhang, David E Clapham. Proc Natl Acad Sci U S A 2018
35
Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate.
László Csanády, Beáta Törocsik. J Gen Physiol 2009
László Csanády, Beáta Törocsik. J Gen Physiol 2009
23
Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate.
Balázs Tóth, Iordan Iordanov, László Csanády. J Gen Physiol 2015
Balázs Tóth, Iordan Iordanov, László Csanády. J Gen Physiol 2015
38
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Yuan Gao, Erhu Cao, David Julius, Yifan Cheng. Nature 2016
Yuan Gao, Erhu Cao, David Julius, Yifan Cheng. Nature 2016
18
TRPV1 structures in distinct conformations reveal activation mechanisms.
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
18
Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.
Frank J P Kühn, Andreas Lückhoff. J Biol Chem 2004
Frank J P Kühn, Andreas Lückhoff. J Biol Chem 2004
17
The TRPM2 ion channel is required for sensitivity to warmth.
Chun-Hsiang Tan, Peter A McNaughton. Nature 2016
Chun-Hsiang Tan, Peter A McNaughton. Nature 2016
17
Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2.
Peilin Yu, Xiwen Xue, Jianmin Zhang, Xupang Hu, Yan Wu, Lin-Hua Jiang, Hongwei Jin, Jianhong Luo, Liangren Zhang, Zhenming Liu,[...]. J Gen Physiol 2017
Peilin Yu, Xiwen Xue, Jianmin Zhang, Xupang Hu, Yan Wu, Lin-Hua Jiang, Hongwei Jin, Jianhong Luo, Liangren Zhang, Zhenming Liu,[...]. J Gen Physiol 2017
45
Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation.
Damian McHugh, Richard Flemming, Shang-Zhong Xu, Anne-Laure Perraud, David J Beech. J Biol Chem 2003
Damian McHugh, Richard Flemming, Shang-Zhong Xu, Anne-Laure Perraud, David J Beech. J Biol Chem 2003
16
Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
Ralf Fliegert, Joanna M Watt, Anja Schöbel, Monika D Rozewitz, Christelle Moreau, Tanja Kirchberger, Mark P Thomas, Wiebke Sick, Andrea C Araujo, Angelika Harneit,[...]. Biochem J 2017
Ralf Fliegert, Joanna M Watt, Anja Schöbel, Monika D Rozewitz, Christelle Moreau, Tanja Kirchberger, Mark P Thomas, Wiebke Sick, Andrea C Araujo, Angelika Harneit,[...]. Biochem J 2017
62
Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Ying Yin, Mengyu Wu, Allen L Hsu, William F Borschel, Mario J Borgnia, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2019
Ying Yin, Mengyu Wu, Allen L Hsu, William F Borschel, Mario J Borgnia, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2019
83
Structural insights into TRPM8 inhibition and desensitization.
Melinda M Diver, Yifan Cheng, David Julius. Science 2019
Melinda M Diver, Yifan Cheng, David Julius. Science 2019
26
Immunocyte Ca2+ influx system mediated by LTRPC2.
Y Sano, K Inamura, A Miyake, S Mochizuki, H Yokoi, H Matsushime, K Furuichi. Science 2001
Y Sano, K Inamura, A Miyake, S Mochizuki, H Yokoi, H Matsushime, K Furuichi. Science 2001
15
Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating.
Balázs Tóth, Iordan Iordanov, László Csanády. Proc Natl Acad Sci U S A 2014
Balázs Tóth, Iordan Iordanov, László Csanády. Proc Natl Acad Sci U S A 2014
45
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels.
Martin Kolisek, Andreas Beck, Andrea Fleig, Reinhold Penner. Mol Cell 2005
Martin Kolisek, Andreas Beck, Andrea Fleig, Reinhold Penner. Mol Cell 2005
15
Conformational ensemble of the human TRPV3 ion channel.
Lejla Zubcevic, Mark A Herzik, Mengyu Wu, William F Borschel, Marscha Hirschi, Albert S Song, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2018
Lejla Zubcevic, Mark A Herzik, Mengyu Wu, William F Borschel, Marscha Hirschi, Albert S Song, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2018
22
Structure of the mouse TRPC4 ion channel.
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
20
Cryo-electron microscopy structure of the TRPV2 ion channel.
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
15
Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents.
Balázs Tóth, László Csanády. Proc Natl Acad Sci U S A 2012
Balázs Tóth, László Csanády. Proc Natl Acad Sci U S A 2012
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UCSF Chimera--a visualization system for exploratory research and analysis.
Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin. J Comput Chem 2004
Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin. J Comput Chem 2004
13
Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction.
Santiago Partida-Sanchez, Andreas Gasser, Ralf Fliegert, Cornelia C Siebrands, Werner Dammermann, Guixiu Shi, Betty J Mousseau, Adriana Sumoza-Toledo, Harivadan Bhagat, Timothy F Walseth,[...]. J Immunol 2007
Santiago Partida-Sanchez, Andreas Gasser, Ralf Fliegert, Cornelia C Siebrands, Werner Dammermann, Guixiu Shi, Betty J Mousseau, Adriana Sumoza-Toledo, Harivadan Bhagat, Timothy F Walseth,[...]. J Immunol 2007
13
Structure and gating mechanism of the transient receptor potential channel TRPV3.
Appu K Singh, Luke L McGoldrick, Alexander I Sobolevsky. Nat Struct Mol Biol 2018
Appu K Singh, Luke L McGoldrick, Alexander I Sobolevsky. Nat Struct Mol Biol 2018
15
Opening of the human epithelial calcium channel TRPV6.
Luke L McGoldrick, Appu K Singh, Kei Saotome, Maria V Yelshanskaya, Edward C Twomey, Robert A Grassucci, Alexander I Sobolevsky. Nature 2018
Luke L McGoldrick, Appu K Singh, Kei Saotome, Maria V Yelshanskaya, Edward C Twomey, Robert A Grassucci, Alexander I Sobolevsky. Nature 2018
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The crystal structure and mutational analysis of human NUDT9.
Betty W Shen, Anne Laure Perraud, Andrew Scharenberg, Barry L Stoddard. J Mol Biol 2003
Betty W Shen, Anne Laure Perraud, Andrew Scharenberg, Barry L Stoddard. J Mol Biol 2003
17
NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase.
Anne-Laure Perraud, Betty Shen, Christopher A Dunn, Karsten Rippe, Megan K Smith, Maurice J Bessman, Barry L Stoddard, Andrew M Scharenberg. J Biol Chem 2003
Anne-Laure Perraud, Betty Shen, Christopher A Dunn, Karsten Rippe, Megan K Smith, Maurice J Bessman, Barry L Stoddard, Andrew M Scharenberg. J Biol Chem 2003
14
Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates.
Iordan Iordanov, Balázs Tóth, Andras Szollosi, László Csanády. Elife 2019
Iordan Iordanov, Balázs Tóth, Andras Szollosi, László Csanády. Elife 2019
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TRPM2: a multifunctional ion channel for calcium signalling.
Adriana Sumoza-Toledo, Reinhold Penner. J Physiol 2011
Adriana Sumoza-Toledo, Reinhold Penner. J Physiol 2011
12
A TRP channel that senses cold stimuli and menthol.
Andrea M Peier, Aziz Moqrich, Anne C Hergarden, Alison J Reeve, David A Andersson, Gina M Story, Taryn J Earley, Ilaria Dragoni, Peter McIntyre, Stuart Bevan,[...]. Cell 2002
Andrea M Peier, Aziz Moqrich, Anne C Hergarden, Alison J Reeve, David A Andersson, Gina M Story, Taryn J Earley, Ilaria Dragoni, Peter McIntyre, Stuart Bevan,[...]. Cell 2002
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Structural insights on TRPV5 gating by endogenous modulators.
Taylor E T Hughes, Ruth A Pumroy, Aysenur Torun Yazici, Marina A Kasimova, Edwin C Fluck, Kevin W Huynh, Amrita Samanta, Sudheer K Molugu, Z Hong Zhou, Vincenzo Carnevale,[...]. Nat Commun 2018
Taylor E T Hughes, Ruth A Pumroy, Aysenur Torun Yazici, Marina A Kasimova, Edwin C Fluck, Kevin W Huynh, Amrita Samanta, Sudheer K Molugu, Z Hong Zhou, Vincenzo Carnevale,[...]. Nat Commun 2018
17
Structure of the human lipid-gated cation channel TRPC3.
Chen Fan, Wooyoung Choi, Weinan Sun, Juan Du, Wei Lü. Elife 2018
Chen Fan, Wooyoung Choi, Weinan Sun, Juan Du, Wei Lü. Elife 2018
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.