Martha Wium, Juliano D Paccez, Luiz F Zerbini. Cells 2018
Times Cited: 30
Times Cited: 30
Times Cited
Times Co-cited
Similarity
TAM receptors are pleiotropic inhibitors of the innate immune response.
Carla V Rothlin, Sourav Ghosh, Elina I Zuniga, Michael B A Oldstone, Greg Lemke. Cell 2007
Carla V Rothlin, Sourav Ghosh, Elina I Zuniga, Michael B A Oldstone, Greg Lemke. Cell 2007
53
TAM receptor signaling in immune homeostasis.
Carla V Rothlin, Eugenio A Carrera-Silva, Lidia Bosurgi, Sourav Ghosh. Annu Rev Immunol 2015
Carla V Rothlin, Eugenio A Carrera-Silva, Lidia Bosurgi, Sourav Ghosh. Annu Rev Immunol 2015
43
TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.
Rachel M A Linger, Amy K Keating, H Shelton Earp, Douglas K Graham. Adv Cancer Res 2008
Rachel M A Linger, Amy K Keating, H Shelton Earp, Douglas K Graham. Adv Cancer Res 2008
40
TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis.
Jonathan H M van der Meer, Tom van der Poll, Cornelis van 't Veer. Blood 2014
Jonathan H M van der Meer, Tom van der Poll, Cornelis van 't Veer. Blood 2014
40
Diversification of TAM receptor tyrosine kinase function.
Anna Zagórska, Paqui G Través, Erin D Lew, Ian Dransfield, Greg Lemke. Nat Immunol 2014
Anna Zagórska, Paqui G Través, Erin D Lew, Ian Dransfield, Greg Lemke. Nat Immunol 2014
36
The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer.
Douglas K Graham, Deborah DeRyckere, Kurtis D Davies, H Shelton Earp. Nat Rev Cancer 2014
Douglas K Graham, Deborah DeRyckere, Kurtis D Davies, H Shelton Earp. Nat Rev Cancer 2014
36
The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases.
T N Stitt, G Conn, M Gore, C Lai, J Bruno, C Radziejewski, K Mattsson, J Fisher, D R Gies, P F Jones. Cell 1995
T N Stitt, G Conn, M Gore, C Lai, J Bruno, C Radziejewski, K Mattsson, J Fisher, D R Gies, P F Jones. Cell 1995
33
Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions.
Jason G Weinger, Kakuri M Omari, Kurt Marsden, Cedric S Raine, Bridget Shafit-Zagardo. Am J Pathol 2009
Jason G Weinger, Kakuri M Omari, Kurt Marsden, Cedric S Raine, Bridget Shafit-Zagardo. Am J Pathol 2009
33
Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily.
Sassan Hafizi, Björn Dahlbäck. FEBS J 2006
Sassan Hafizi, Björn Dahlbäck. FEBS J 2006
30
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family.
Q Lu, G Lemke. Science 2001
Q Lu, G Lemke. Science 2001
30
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.
Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke. Elife 2014
Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke. Elife 2014
26
23
Tyro-3 family receptors are essential regulators of mammalian spermatogenesis.
Q Lu, M Gore, Q Zhang, T Camenisch, S Boast, F Casagranda, C Lai, M K Skinner, R Klein, G K Matsushima,[...]. Nature 1999
Q Lu, M Gore, Q Zhang, T Camenisch, S Boast, F Casagranda, C Lai, M K Skinner, R Klein, G K Matsushima,[...]. Nature 1999
23
TAM receptors and the clearance of apoptotic cells.
Greg Lemke, Tal Burstyn-Cohen. Ann N Y Acad Sci 2010
Greg Lemke, Tal Burstyn-Cohen. Ann N Y Acad Sci 2010
23
TAM receptors regulate multiple features of microglial physiology.
Lawrence Fourgeaud, Paqui G Través, Yusuf Tufail, Humberto Leal-Bailey, Erin D Lew, Patrick G Burrola, Perri Callaway, Anna Zagórska, Carla V Rothlin, Axel Nimmerjahn,[...]. Nature 2016
Lawrence Fourgeaud, Paqui G Través, Yusuf Tufail, Humberto Leal-Bailey, Erin D Lew, Patrick G Burrola, Perri Callaway, Anna Zagórska, Carla V Rothlin, Axel Nimmerjahn,[...]. Nature 2016
23
Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination.
Michele D Binder, Holly S Cate, Anne L Prieto, Dennis Kemper, Helmut Butzkueven, Melissa M Gresle, Tania Cipriani, Vilija G Jokubaitis, Peter Carmeliet, Trevor J Kilpatrick. J Neurosci 2008
Michele D Binder, Holly S Cate, Anne L Prieto, Dennis Kemper, Helmut Butzkueven, Melissa M Gresle, Tania Cipriani, Vilija G Jokubaitis, Peter Carmeliet, Trevor J Kilpatrick. J Neurosci 2008
23
Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment.
Kayla V Myers, Sarah R Amend, Kenneth J Pienta. Mol Cancer 2019
Kayla V Myers, Sarah R Amend, Kenneth J Pienta. Mol Cancer 2019
23
Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells.
Heather M Seitz, Todd D Camenisch, Greg Lemke, H Shelton Earp, Glenn K Matsushima. J Immunol 2007
Heather M Seitz, Todd D Camenisch, Greg Lemke, H Shelton Earp, Glenn K Matsushima. J Immunol 2007
20
A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation.
Susan Sather, Karla D Kenyon, Jerry B Lefkowitz, Xiayuan Liang, Brian C Varnum, Peter M Henson, Douglas K Graham. Blood 2007
Susan Sather, Karla D Kenyon, Jerry B Lefkowitz, Xiayuan Liang, Brian C Varnum, Peter M Henson, Douglas K Graham. Blood 2007
20
Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood.
C Ekman, J Stenhoff, B Dahlbäck. J Thromb Haemost 2010
C Ekman, J Stenhoff, B Dahlbäck. J Thromb Haemost 2010
20
T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response.
Eugenio A Carrera Silva, Pamela Y Chan, Leonel Joannas, Andrea E Errasti, Nicola Gagliani, Lidia Bosurgi, Maurice Jabbour, Anthony Perry, Faye Smith-Chakmakova, Daniel Mucida,[...]. Immunity 2013
Eugenio A Carrera Silva, Pamela Y Chan, Leonel Joannas, Andrea E Errasti, Nicola Gagliani, Lidia Bosurgi, Maurice Jabbour, Anthony Perry, Faye Smith-Chakmakova, Daniel Mucida,[...]. Immunity 2013
20
Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.
Wen-I Tsou, Khanh-Quynh N Nguyen, Daniel A Calarese, Scott J Garforth, Anita L Antes, Sergey V Smirnov, Steve C Almo, Raymond B Birge, Sergei V Kotenko. J Biol Chem 2014
Wen-I Tsou, Khanh-Quynh N Nguyen, Daniel A Calarese, Scott J Garforth, Anita L Antes, Sergey V Smirnov, Steve C Almo, Raymond B Birge, Sergei V Kotenko. J Biol Chem 2014
20
Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE.
Jacob J Orme, Yong Du, Kamala Vanarsa, Jessica Mayeux, Li Li, Azza Mutwally, Cristina Arriens, Soyoun Min, Jack Hutcheson, Laurie S Davis,[...]. Clin Immunol 2016
Jacob J Orme, Yong Du, Kamala Vanarsa, Jessica Mayeux, Li Li, Azza Mutwally, Cristina Arriens, Soyoun Min, Jack Hutcheson, Laurie S Davis,[...]. Clin Immunol 2016
20
Growth arrest specific gene 6 protein concentration in cerebrospinal fluid correlates with relapse severity in multiple sclerosis.
P P Sainaghi, L Collimedaglia, F Alciato, R Molinari, D Sola, E Ranza, P Naldi, F Monaco, M Leone, M Pirisi,[...]. Mediators Inflamm 2013
P P Sainaghi, L Collimedaglia, F Alciato, R Molinari, D Sola, E Ranza, P Naldi, F Monaco, M Leone, M Pirisi,[...]. Mediators Inflamm 2013
22
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
Magdalena Paolino, Axel Choidas, Stephanie Wallner, Blanka Pranjic, Iris Uribesalgo, Stefanie Loeser, Amanda M Jamieson, Wallace Y Langdon, Fumiyo Ikeda, Juan Pablo Fededa,[...]. Nature 2014
Magdalena Paolino, Axel Choidas, Stephanie Wallner, Blanka Pranjic, Iris Uribesalgo, Stefanie Loeser, Amanda M Jamieson, Wallace Y Langdon, Fumiyo Ikeda, Juan Pablo Fededa,[...]. Nature 2014
20
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases.
K Nagata, K Ohashi, T Nakano, H Arita, C Zong, H Hanafusa, K Mizuno. J Biol Chem 1996
K Nagata, K Ohashi, T Nakano, H Arita, C Zong, H Hanafusa, K Mizuno. J Biol Chem 1996
20
TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy.
Yemsratch T Akalu, Carla V Rothlin, Sourav Ghosh. Immunol Rev 2017
Yemsratch T Akalu, Carla V Rothlin, Sourav Ghosh. Immunol Rev 2017
20
Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6.
B C Varnum, C Young, G Elliott, A Garcia, T D Bartley, Y W Fridell, R W Hunt, G Trail, C Clogston, R J Toso. Nature 1995
B C Varnum, C Young, G Elliott, A Garcia, T D Bartley, Y W Fridell, R W Hunt, G Trail, C Clogston, R J Toso. Nature 1995
20
TAM receptor function in the retinal pigment epithelium.
Dipti Prasad, Carla Vanina Rothlin, Patrick Burrola, Tal Burstyn-Cohen, Qingxian Lu, Pablo Garcia de Frutos, Greg Lemke. Mol Cell Neurosci 2006
Dipti Prasad, Carla Vanina Rothlin, Patrick Burrola, Tal Burstyn-Cohen, Qingxian Lu, Pablo Garcia de Frutos, Greg Lemke. Mol Cell Neurosci 2006
16
Structural basis for Gas6-Axl signalling.
Takako Sasaki, Pjotr G Knyazev, Naomi J Clout, Yuri Cheburkin, Walter Göhring, Axel Ullrich, Rupert Timpl, Erhard Hohenester. EMBO J 2006
Takako Sasaki, Pjotr G Knyazev, Naomi J Clout, Yuri Cheburkin, Walter Göhring, Axel Ullrich, Rupert Timpl, Erhard Hohenester. EMBO J 2006
16
Cloning and mRNA expression analysis of a novel human protooncogene, c-mer.
D K Graham, T L Dawson, D L Mullaney, H R Snodgrass, H S Earp. Cell Growth Differ 1994
D K Graham, T L Dawson, D L Mullaney, H R Snodgrass, H S Earp. Cell Growth Differ 1994
16
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.
J P O'Bryan, R A Frye, P C Cogswell, A Neubauer, B Kitch, C Prokop, R Espinosa, M M Le Beau, H S Earp, E T Liu. Mol Cell Biol 1991
J P O'Bryan, R A Frye, P C Cogswell, A Neubauer, B Kitch, C Prokop, R Espinosa, M M Le Beau, H S Earp, E T Liu. Mol Cell Biol 1991
16
R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.
Sacha J Holland, Alison Pan, Christian Franci, Yuanming Hu, Betty Chang, Weiqun Li, Matt Duan, Allan Torneros, Jiaxin Yu, Thilo J Heckrodt,[...]. Cancer Res 2010
Sacha J Holland, Alison Pan, Christian Franci, Yuanming Hu, Betty Chang, Weiqun Li, Matt Duan, Allan Torneros, Jiaxin Yu, Thilo J Heckrodt,[...]. Cancer Res 2010
16
16
Soluble TAM receptor tyrosine kinases in rheumatoid arthritis: correlation with disease activity and bone destruction.
L Xu, F Hu, H Zhu, X Liu, L Shi, Y Li, H Zhong, Y Su. Clin Exp Immunol 2018
L Xu, F Hu, H Zhu, X Liu, L Shi, Y Li, H Zhong, Y Su. Clin Exp Immunol 2018
33
Growth Arrest Specific 6 Concentration is Increased in the Cerebrospinal Fluid of Patients with Alzheimer's Disease.
Pier Paolo Sainaghi, Mattia Bellan, Franco Lombino, Federica Alciato, Miryam Carecchio, Daniela Galimberti, Chiara Fenoglio, Elio Scarpini, Roberto Cantello, Mario Pirisi,[...]. J Alzheimers Dis 2017
Pier Paolo Sainaghi, Mattia Bellan, Franco Lombino, Federica Alciato, Miryam Carecchio, Daniela Galimberti, Chiara Fenoglio, Elio Scarpini, Roberto Cantello, Mario Pirisi,[...]. J Alzheimers Dis 2017
16
The non-invasive serum biomarker soluble Axl accurately detects advanced liver fibrosis and cirrhosis.
Katharina Staufer, Mirko Dengler, Heidemarie Huber, Rodrig Marculescu, Rudolf Stauber, Carolin Lackner, Hans-Peter Dienes, Danijel Kivaranovic, Christian Schachner, Markus Zeitlinger,[...]. Cell Death Dis 2017
Katharina Staufer, Mirko Dengler, Heidemarie Huber, Rodrig Marculescu, Rudolf Stauber, Carolin Lackner, Hans-Peter Dienes, Danijel Kivaranovic, Christian Schachner, Markus Zeitlinger,[...]. Cell Death Dis 2017
17
TAM receptor tyrosine kinases: expression, disease and oncogenesis in the central nervous system.
Angela M Pierce, Amy K Keating. Brain Res 2014
Angela M Pierce, Amy K Keating. Brain Res 2014
16
Phagocytosis and clearance of apoptotic cells is mediated by MER.
R S Scott, E J McMahon, S M Pop, E A Reap, R Caricchio, P L Cohen, H S Earp, G K Matsushima. Nature 2001
R S Scott, E J McMahon, S M Pop, E A Reap, R Caricchio, P L Cohen, H S Earp, G K Matsushima. Nature 2001
16
The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade.
G Manfioletti, C Brancolini, G Avanzi, C Schneider. Mol Cell Biol 1993
G Manfioletti, C Brancolini, G Avanzi, C Schneider. Mol Cell Biol 1993
16
Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury.
Laura Llacuna, Cristina Bárcena, Lola Bellido-Martín, Laura Fernández, Milica Stefanovic, Montserrat Marí, Carmen García-Ruiz, José C Fernández-Checa, Pablo García de Frutos, Albert Morales. Hepatology 2010
Laura Llacuna, Cristina Bárcena, Lola Bellido-Martín, Laura Fernández, Milica Stefanovic, Montserrat Marí, Carmen García-Ruiz, José C Fernández-Checa, Pablo García de Frutos, Albert Morales. Hepatology 2010
16
Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggers.
Aleksander M Grabiec, Anu Goenka, Mark E Fife, Toshifumi Fujimori, Tracy Hussell. Eur J Immunol 2018
Aleksander M Grabiec, Anu Goenka, Mark E Fife, Toshifumi Fujimori, Tracy Hussell. Eur J Immunol 2018
17
An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system.
C Lai, G Lemke. Neuron 1991
C Lai, G Lemke. Neuron 1991
16
A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock.
T D Camenisch, B H Koller, H S Earp, G K Matsushima. J Immunol 1999
T D Camenisch, B H Koller, H S Earp, G K Matsushima. J Immunol 1999
16
Molecular insights of Gas6/TAM in cancer development and therapy.
Guiling Wu, Zhiqiang Ma, Wei Hu, Dongjin Wang, Bing Gong, Chongxi Fan, Shuai Jiang, Tian Li, Jianyuan Gao, Yang Yang. Cell Death Dis 2017
Guiling Wu, Zhiqiang Ma, Wei Hu, Dongjin Wang, Bing Gong, Chongxi Fan, Shuai Jiang, Tian Li, Jianyuan Gao, Yang Yang. Cell Death Dis 2017
16
Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor.
Yumi Yokoyama, Erin D Lew, Ruth Seelige, Elizabeth A Tindall, Colin Walsh, Patrick C Fagan, Jack Y Lee, Robin Nevarez, Joanne Oh, Kathleen D Tucker,[...]. Cancer Res 2019
Yumi Yokoyama, Erin D Lew, Ruth Seelige, Elizabeth A Tindall, Colin Walsh, Patrick C Fagan, Jack Y Lee, Robin Nevarez, Joanne Oh, Kathleen D Tucker,[...]. Cancer Res 2019
16
Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity.
Pedro Recarte-Pelz, Dolors Tàssies, Gerard Espinosa, Begoña Hurtado, Núria Sala, Ricard Cervera, Joan Carles Reverter, Pablo García de Frutos. Arthritis Res Ther 2013
Pedro Recarte-Pelz, Dolors Tàssies, Gerard Espinosa, Begoña Hurtado, Núria Sala, Ricard Cervera, Joan Carles Reverter, Pablo García de Frutos. Arthritis Res Ther 2013
13
Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors.
Suchita Bhattacharyya, Anna Zagórska, Erin D Lew, Bimmi Shrestha, Carla V Rothlin, John Naughton, Michael S Diamond, Greg Lemke, John A T Young. Cell Host Microbe 2013
Suchita Bhattacharyya, Anna Zagórska, Erin D Lew, Bimmi Shrestha, Carla V Rothlin, John Naughton, Michael S Diamond, Greg Lemke, John A T Young. Cell Host Microbe 2013
13
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