Pontus Orning, Dan Weng, Kristian Starheim, Dmitry Ratner, Zachary Best, Bettina Lee, Alexandria Brooks, Shiyu Xia, Hao Wu, Michelle A Kelliher, Scott B Berger, Peter J Gough, John Bertin, Megan M Proulx, Jon D Goguen, Nobuhiko Kayagaki, Katherine A Fitzgerald, Egil Lien. Science 2018
Times Cited: 327
Times Cited: 327
Times Cited
Times Co-cited
Similarity
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
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Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection.
Joseph Sarhan, Beiyun C Liu, Hayley I Muendlein, Peng Li, Rachael Nilson, Amy Y Tang, Anthony Rongvaux, Stephen C Bunnell, Feng Shao, Douglas R Green,[...]. Proc Natl Acad Sci U S A 2018
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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
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Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin.
Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Shao. Nature 2017
Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Shao. Nature 2017
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Pore-forming activity and structural autoinhibition of the gasdermin family.
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
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Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells.
Zhiwei Zhou, Huabin He, Kun Wang, Xuyan Shi, Yupeng Wang, Ya Su, Yao Wang, Da Li, Wang Liu, Yongliang Zhang,[...]. Science 2020
Zhiwei Zhou, Huabin He, Kun Wang, Xuyan Shi, Yupeng Wang, Ya Su, Yao Wang, Da Li, Wang Liu, Yongliang Zhang,[...]. Science 2020
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Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.
Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S Alnemri. Nat Commun 2017
Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S Alnemri. Nat Commun 2017
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Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
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Inflammatory caspases are innate immune receptors for intracellular LPS.
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
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Non-canonical inflammasome activation targets caspase-11.
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
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GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death.
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GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes.
Robin A Aglietti, Alberto Estevez, Aaron Gupta, Monica Gonzalez Ramirez, Peter S Liu, Nobuhiko Kayagaki, Claudio Ciferri, Vishva M Dixit, Erin C Dueber. Proc Natl Acad Sci U S A 2016
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Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly.
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Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death.
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The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
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Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation.
Corey Rogers, Dan A Erkes, Alexandria Nardone, Andrew E Aplin, Teresa Fernandes-Alnemri, Emad S Alnemri. Nat Commun 2019
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Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.
Jianjin Shi, Wenqing Gao, Feng Shao. Trends Biochem Sci 2017
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Gasdermin D plays a vital role in the generation of neutrophil extracellular traps.
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Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages.
Cornelius Y Taabazuing, Marian C Okondo, Daniel A Bachovchin. Cell Chem Biol 2017
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PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
Junwei Hou, Rongce Zhao, Weiya Xia, Chiung-Wen Chang, Yun You, Jung-Mao Hsu, Lei Nie, Yeh Chen, Yu-Chuan Wang, Chunxiao Liu,[...]. Nat Cell Biol 2020
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The gasdermins, a protein family executing cell death and inflammation.
Petr Broz, Pablo Pelegrín, Feng Shao. Nat Rev Immunol 2020
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ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation.
Sebastian Rühl, Kateryna Shkarina, Benjamin Demarco, Rosalie Heilig, José Carlos Santos, Petr Broz. Science 2018
Sebastian Rühl, Kateryna Shkarina, Benjamin Demarco, Rosalie Heilig, José Carlos Santos, Petr Broz. Science 2018
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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
Jun Jacob Hu, Xing Liu, Shiyu Xia, Zhibin Zhang, Ying Zhang, Jingxia Zhao, Jianbin Ruan, Xuemei Luo, Xiwen Lou, Yang Bai,[...]. Nat Immunol 2020
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Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
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Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis.
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Pyroptosis: host cell death and inflammation.
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Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation.
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Inflammasomes: mechanism of assembly, regulation and signalling.
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Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
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Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps.
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Shigella flexneri induces apoptosis in infected macrophages.
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Cryo-EM structure of the gasdermin A3 membrane pore.
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Succination inactivates gasdermin D and blocks pyroptosis.
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Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.